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Erschienen in: Acta Neurochirurgica 12/2011

01.12.2011 | Clinical Article

Hardware-related infections after deep brain stimulation surgery: review of incidence, severity and management in 212 single-center procedures in the first year after implantation

verfasst von: Massimo Piacentino, Manuela Pilleri, Luigi Bartolomei

Erschienen in: Acta Neurochirurgica | Ausgabe 12/2011

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Abstract

Background

Device-related infection is a common occurrence after deep brain stimulation (DBS) surgery, and may result in additional interventions and a loss of efficacy of therapy. This retrospective review aimed to evaluate the incidence, severity and management of device-related infections in 212 DBS procedures performed in our institute.

Methods

Data on 106 patients, in whom 212 DBS procedures were performed between 2001 and 2011 at our institute by a single neurosurgeon (M.P.), were reviewed to assess the incidence, severity, management and clinical characteristics of infections in the first year after the implantation of a DBS system.

Results

Infections occurred in 8.5% of patients and 4.2% of procedures. Of the nine infections, eight involved the neurostimulator and extensions, and one the whole system. The infections occurred 30.7 days after implantation: 7 within 30 days and 2 within 6 months. Infected and uninfected patients were comparable in terms of age, sex, indication for DBS implantation and neurostimulator location. In eight cases, the system components involved were removed and re-implanted after 3 months, while in one case the complete hardware was removed and not re-implanted.

Conclusion

The overall incidence of postoperative infections after DBS system implantation was 4.2%; this rate decreased over time. All infections required further surgery. Correct and timely management of partial infections may result in successful salvage of part of the system.
Literatur
1.
Zurück zum Zitat Bhatia S, Zhang K, Oh M, Angle C, Whiting D (2010) Infections and hardware salvage after deep brain stimulation surgery: a single-center study and review of literature. Stereotact Funct Neurosurgery 88:147–155CrossRef Bhatia S, Zhang K, Oh M, Angle C, Whiting D (2010) Infections and hardware salvage after deep brain stimulation surgery: a single-center study and review of literature. Stereotact Funct Neurosurgery 88:147–155CrossRef
2.
Zurück zum Zitat Blomstedt P, Hariz M (2005) Hardware-related complications of deep brain stimulation: a ten-year experience. Acta Neurochir 147:1061–1064CrossRef Blomstedt P, Hariz M (2005) Hardware-related complications of deep brain stimulation: a ten-year experience. Acta Neurochir 147:1061–1064CrossRef
3.
Zurück zum Zitat Constantoyannis C, Berk C, Honey CR, Mendez I, Brownstone RM (2005) Reducing hardware-related complications of deep brain stimulation. Can J Neurol Sci 32:194–200PubMed Constantoyannis C, Berk C, Honey CR, Mendez I, Brownstone RM (2005) Reducing hardware-related complications of deep brain stimulation. Can J Neurol Sci 32:194–200PubMed
4.
Zurück zum Zitat Kenney C, Simpson R, Hunter C, Ondo W, Almaguer M, Davidson A, Jankovic J (2007) Short-term and long-term safety of deep brain stimulation in the treatment of movement disorders. J Neurosurg 106:621–625PubMedCrossRef Kenney C, Simpson R, Hunter C, Ondo W, Almaguer M, Davidson A, Jankovic J (2007) Short-term and long-term safety of deep brain stimulation in the treatment of movement disorders. J Neurosurg 106:621–625PubMedCrossRef
5.
Zurück zum Zitat Kondziolka D, Whiting D, Germanwala A, Oh M (2002) Hardware-related complications after placement of thalamic deep brain stimulator systems. Stereotact Funct Neurosurg 79:228–233PubMedCrossRef Kondziolka D, Whiting D, Germanwala A, Oh M (2002) Hardware-related complications after placement of thalamic deep brain stimulator systems. Stereotact Funct Neurosurg 79:228–233PubMedCrossRef
6.
Zurück zum Zitat Lyons KE, Wilkinson SB, Overman J, Pahwa R (2004) Surgical and hardware complications of subthalamic stimulation: a series of 160 procedures. Neurology 62:612–616 Lyons KE, Wilkinson SB, Overman J, Pahwa R (2004) Surgical and hardware complications of subthalamic stimulation: a series of 160 procedures. Neurology 62:612–616
7.
Zurück zum Zitat Miller JP, Acar F, Burchiel KJ (2009) Significant reduction in stereotactic and functional neurosurgical hardware infection after local neomycin/polymyxin application. J Neurosurg 110:247–250PubMedCrossRef Miller JP, Acar F, Burchiel KJ (2009) Significant reduction in stereotactic and functional neurosurgical hardware infection after local neomycin/polymyxin application. J Neurosurg 110:247–250PubMedCrossRef
8.
Zurück zum Zitat Oh M, Abosch A, Kim SH, Lang AE, Lozano AM (2002) Long-term hardware-related complications of deep brain stimulation. Neurosurgery 50:1268–1276PubMed Oh M, Abosch A, Kim SH, Lang AE, Lozano AM (2002) Long-term hardware-related complications of deep brain stimulation. Neurosurgery 50:1268–1276PubMed
9.
Zurück zum Zitat Paluzzi A, Belli A, Bain P, Liu X, Aziz TM (2006) Operative and hardware complications of deep brain stimulation for movement disorders. Br J Neurosurg 20:290–295PubMedCrossRef Paluzzi A, Belli A, Bain P, Liu X, Aziz TM (2006) Operative and hardware complications of deep brain stimulation for movement disorders. Br J Neurosurg 20:290–295PubMedCrossRef
10.
Zurück zum Zitat Seijo FJ, Alvarezz-Vega MA, Gutierrez JC, Fdez-Glez F, Lozano B (2007) Complications in subthalamic nucleus stimulation surgery for treatment of Parkinson’s disease: review of 272 procedures. Acta Neurochir 149:867–876CrossRef Seijo FJ, Alvarezz-Vega MA, Gutierrez JC, Fdez-Glez F, Lozano B (2007) Complications in subthalamic nucleus stimulation surgery for treatment of Parkinson’s disease: review of 272 procedures. Acta Neurochir 149:867–876CrossRef
11.
Zurück zum Zitat Sillay KA, Larson PS, Starr PA (2008) Deep brain stimulator hardware-related infections: incidence and management in a large series. Neurosurgery 62:360–367PubMedCrossRef Sillay KA, Larson PS, Starr PA (2008) Deep brain stimulator hardware-related infections: incidence and management in a large series. Neurosurgery 62:360–367PubMedCrossRef
12.
Zurück zum Zitat Temel Y, Ackermans L, Celik H, Spincemaille GH, Van Der Linden C, Walenkamp GH, Van De Kar T, Visser-Vandewalle V (2004) Management of hardware infections following deep brain stimulation. Acta Neurochir 146:355–361CrossRef Temel Y, Ackermans L, Celik H, Spincemaille GH, Van Der Linden C, Walenkamp GH, Van De Kar T, Visser-Vandewalle V (2004) Management of hardware infections following deep brain stimulation. Acta Neurochir 146:355–361CrossRef
13.
Zurück zum Zitat Voges J, Waerzeggers Y, Maarouf M, Lehrke R, Koulousakis A, Lenartz D, Sturm V (2006) Deep-brain stimulation: long-term analysis of complications caused by hardware and surgery—experiences from a single centre. J Neurol Neurosurg Psychiatry 77:868–872PubMedCrossRef Voges J, Waerzeggers Y, Maarouf M, Lehrke R, Koulousakis A, Lenartz D, Sturm V (2006) Deep-brain stimulation: long-term analysis of complications caused by hardware and surgery—experiences from a single centre. J Neurol Neurosurg Psychiatry 77:868–872PubMedCrossRef
Metadaten
Titel
Hardware-related infections after deep brain stimulation surgery: review of incidence, severity and management in 212 single-center procedures in the first year after implantation
verfasst von
Massimo Piacentino
Manuela Pilleri
Luigi Bartolomei
Publikationsdatum
01.12.2011
Verlag
Springer Vienna
Erschienen in
Acta Neurochirurgica / Ausgabe 12/2011
Print ISSN: 0001-6268
Elektronische ISSN: 0942-0940
DOI
https://doi.org/10.1007/s00701-011-1130-2

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