nach oben

Acta Neurochirurgica

Erschienen in:

01.09.2012 | Experimental research

Diffusion tensor imaging in hydrocephalus—findings before and after shunt surgery

verfasst von: Michael Scheel, Torsten Diekhoff, Christian Sprung, Karl-Titus Hoffmann

Erschienen in: Acta Neurochirurgica | Ausgabe 9/2012

Einloggen, um Zugang zu erhalten

Abstract

Background

To evaluate changes in diffusion tensor imaging (DTI)-derived parameters in patients with hydrocephalus (HC) before and several weeks after shunt surgery.

Methods

Thirteen HC patients were examined with DTI before and after shunt surgery. In a combined region of interest and whole brain voxel-based analysis, different DTI parameters were compared with an age-matched control group.

Results

Alteration of DTI parameters in HC patients and changes after shunt surgery are regionally different. HC patients show an increase in fractional anisotropy values based on increases in parallel diffusivity in the corticospinal tract. On the other hand, reduced fractional anisotropy values are found in the corpus callosum of HC patients. Following shunt surgery, all DTI parameters showed a trend towards normalization, yet differences to healthy control subjects remained.

Conclusion

Our results show that DTI parameter changes are regionally dependent and need a careful interpretation of the underlying diffusivities to serve as a diagnostic or follow-up measure in patients with hydrocephalus.

Nur mit Berechtigung zugänglich

Air EL, Yuan W, Holland SK, Jones BV, Bierbrauer K, Altaye M, Mangano FT (2010) Longitudinal comparison of pre- and postoperative diffusion tensor imaging parameters in young children with hydrocephalus. J Neurosurg Pediatr 5:385–391PubMedCrossRef

Assaf Y, Ben-Sira L, Constantini S, Chang LC, Beni-Adani L (2006) Diffusion tensor imaging in hydrocephalus: initial experience. AJNR Am J Neuroradiol 27:1717–1724PubMed

Basser PJ, Pierpaoli C (1998) A simplified method to measure the diffusion tensor from seven MR images. Magn Reson Med 39:928–934PubMedCrossRef

Beaulieu C (2009) The biological basis of diffusion anisotropy. In: Johansen-Berg H, Behrens TEJ, editors. Diffusion MRI: From Quantitative Measurement to In-Vivo Neuroanatomy. Academic Press; 2009. p. 105–127.

Bork T, Hogg A, Lempen M, Müller D, Joss D, Bardyn T, Büchler P, Keppner H, Braun S, Tardy Y, Burger J (2010) Development and in-vitro characterization of an implantable flow sensing transducer for hydrocephalus. Biomed Microdevices 12:607–618PubMedCrossRef

Braun KPJ, Gooskens RHJM, Vandertop WP, Tulleken CAF, van der Grond J (2003) 1 H magnetic resonance spectroscopy in human hydrocephalus. J Magn Reson Imaging 17:291–299PubMedCrossRef

Budde MD, Xie M, Cross AH, Song S-K (2009) Axial diffusivity is the primary correlate of axonal injury in the experimental autoimmune encephalomyelitis spinal cord: a quantitative pixelwise analysis. J Neurosci 29:2805–2813PubMedCrossRef

Drake JM, Kestle JR, Tuli S (2000) CSF shunts 50 years on—past, present and future. Childs Nerv Syst 16:800–804PubMedCrossRef

Eide PK, Sorteberg W (2010) Diagnostic intracranial pressure monitoring and surgical management in idiopathic normal pressure hydrocephalus: a 6-year review of 214 patients. Neurosurgery 66:80–91PubMedCrossRef

10.

Hasan KM, Eluvathingal TJ, Kramer LA, Ewing-Cobbs L, Dennis M, Fletcher JM (2008) White matter microstructural abnormalities in children with spina bifida myelomeningocele and hydrocephalus: a diffusion tensor tractography study of the association pathways. J Magn Reson Imaging 27:700–709PubMedCrossRef

11.

Hattingen E, Jurcoane A, Melber J, Blasel S, Zanella FE, Neumann-Haefelin T, Singer OC (2010) Diffusion tensor imaging in patients with adult chronic idiopathic hydrocephalus. Neurosurgery 66:917–924PubMedCrossRef

12.

Hattori T, Ito K, Aoki S, Yuasa T, Sato R, Ishikawa M, Sawaura H, Hori M, Mizusawa H (2012) White matter alteration in idiopathic normal pressure hydrocephalus: tract-based spatial statistics study. AJNR Am J Neuroradiol 33:97–103PubMedCrossRef

13.

Hattori T, Yuasa T, Aoki S, Sato R, Sawaura H, Mori T, Mizusawa H (2011) Altered microstructure in corticospinal tract in idiopathic normal pressure hydrocephalus: comparison with Alzheimer disease and Parkinson disease with dementia. AJNR Am J Neuroradiol 32:1681–1687PubMedCrossRef

14.

Hong YJ, Yoon B, Shim YS, Cho AH, Lim SC, Ahn KJ, Yang DW (2010) Differences in microstructural alterations of the hippocampus in Alzheimer disease and idiopathic normal pressure hydrocephalus: a diffusion tensor imaging study. AJNR Am J Neuroradiol 31:1867–1872PubMedCrossRef

15.

Jang SH, Ho Kim S (2011) Diffusion tensor imaging following shunt in a patient with hydrocephalus. J Neuroimaging 21:69–72PubMedCrossRef

16.

Kanno S, Abe N, Saito M, Takagi M, Nishio Y, Hayashi A, Uchiyama M, Hanaki R, Kikuchi H, Hiraoka K, Yamasaki H, Iizuka O, Takeda A, Itoyama Y, Takahashi S, Mori E (2011) White matter involvement in idiopathic normal pressure hydrocephalus: a voxel-based diffusion tensor imaging study. J Neurol 258:1949–1957PubMedCrossRef

17.

Lenfeldt N, Larsson A, Nyberg L, Birgander R, Eklund A, Malm J (2011) Diffusion tensor imaging reveals supplementary lesions to frontal white matter in idiopathic normal pressure hydrocephalus. Neurosurgery 68:1586–1593PubMedCrossRef

18.

Nichols TE, Holmes AP (2002) Nonparametric permutation tests for functional neuroimaging: a primer with examples. Hum Brain Mapp 15:1–25PubMedCrossRef

19.

Osuka S, Matsushita A, Yamamoto T, Saotome K, Isobe T, Nagatomo Y, Masumoto T, Komatsu Y, Ishikawa E, Matsumura A (2010) Evaluation of ventriculomegaly using diffusion tensor imaging: correlations with chronic hydrocephalus and atrophy. J Neurosurg 112:832–839PubMedCrossRef

20.

Pierpaoli C, Barnett A, Pajevic S, Chen R, Penix LR, Virta A, Basser P (2001) Water diffusion changes in wallerian degeneration and their dependence on white matter architecture. NeuroImage 13:1174–1185PubMedCrossRef

21.

Relkin N, Marmarou A, Klinge P, Bergsneider M, Black PM (2005) Diagnosing idiopathic normal-pressure hydrocephalus. Neurosurgery 57:S4–16, discussion ii–vPubMed

22.

Shannon CN, Simon TD, Reed GT, Franklin FA, Kirby RS, Kilgore ML, Wellons JC 3rd (2011) The economic impact of ventriculoperitoneal shunt failure. J Neurosurg Pediatr 8:593–599PubMedCrossRef

23.

Shiino A, Nishida Y, Yasuda H, Suzuki M, Matsuda M, Inubushi T (2004) Magnetic resonance spectroscopic determination of a neuronal and axonal marker in white matter predicts reversibility of deficits in secondary normal pressure hydrocephalus. J Neurol Neurosurg Psychiatr 75:1141–1148PubMedCrossRef

24.

Smith SM, Jenkinson M, Johansen-Berg H, Rueckert D, Nichols TE, Mackay CE, Watkins KE, Ciccarelli O, Cader MZ, Matthews PM, Behrens TEJ (2006) Tract-based spatial statistics: voxelwise analysis of multi-subject diffusion data. NeuroImage 31:1487–1505PubMedCrossRef

25.

Smith SM, Johansen-Berg H, Jenkinson M, Rueckert D, Nichols TE, Miller KL, Robson MD, Jones DK, Klein JC, Bartsch AJ, Behrens TEJ (2007) Acquisition and voxelwise analysis of multi-subject diffusion data with tract-based spatial statistics. Nat Protoc 2:499–503PubMedCrossRef

26.

Song S-K, Yoshino J, Le TQ, Lin S-J, Sun S-W, Cross AH, Armstrong RC (2005) Demyelination increases radial diffusivity in corpus callosum of mouse brain. NeuroImage 26:132–140PubMedCrossRef

27.

Wieshmann UC, Symms MR, Parker GJ, Clark CA, Lemieux L, Barker GJ, Shorvon SD (2000) Diffusion tensor imaging demonstrates deviation of fibres in normal appearing white matter adjacent to a brain tumour. J Neurol Neurosurg Psychiatr 68:501–503PubMedCrossRef

28.

Yuan W, Mangano FT, Air EL, Holland SK, Jones BV, Altaye M, Bierbrauer K (2009) Anisotropic diffusion properties in infants with hydrocephalus: a diffusion tensor imaging study. Am J Neuroradiol 30:1792–1798PubMedCrossRef

Titel: Diffusion tensor imaging in hydrocephalus—findings before and after shunt surgery
verfasst von: Michael Scheel
Torsten Diekhoff
Christian Sprung
Karl-Titus Hoffmann
Publikationsdatum: 01.09.2012
Verlag: Springer Vienna
Erschienen in: Acta Neurochirurgica / Ausgabe 9/2012
Print ISSN: 0001-6268
Elektronische ISSN: 0942-0940
DOI: https://doi.org/10.1007/s00701-012-1377-2

Leitlinien kompakt für die Neurologie

Mit medbee Pocketcards sicher entscheiden.

^{Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag}

Kostenlos registrieren

Neu im Fachgebiet Neurologie

23.04.2024 | Demenz | Nachrichten

Update Neurologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Diffusion tensor imaging in hydrocephalus—findings before and after shunt surgery

Abstract

Background

Methods

Results

Conclusion

Leitlinien kompakt für die Neurologie

Neu im Fachgebiet Neurologie

Demenzkranke durch Antipsychotika vielfach gefährdet

Parkinson-Therapie im Wandel – aktuelle Leitlinie im Fokus

Auf diese Krankheiten bei Geflüchteten sollten Sie vorbereitet sein

Hustenstiller lindert Agitation bei Alzheimer

Update Neurologie

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Abstract

Background

Methods

Results

Conclusion

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 9/2012

Umbilical cord stem cells: the hidden swan in a family of ugly ducklings

Evaluation of an institutional guideline for the treatment of cerebrospinal fluid shunt-associated infections

Risk factors and tumor response associated with hydrocephalus after gamma knife radiosurgery for vestibular schwannoma

Frameless image-guided stereotaxy with real-time visual feedback for brain biopsy

Chronic subdural haematoma in elderly patients: a retrospective analysis of 322 patients between the ages of 65–94 years

Erratum to: The IMPACT prognosis calculator used in patients with severe traumatic brain injury treated with an ICP-targeted therapy

Leitlinien kompakt für die Neurologie

Neu im Fachgebiet Neurologie

Demenzkranke durch Antipsychotika vielfach gefährdet

Parkinson-Therapie im Wandel – aktuelle Leitlinie im Fokus

Auf diese Krankheiten bei Geflüchteten sollten Sie vorbereitet sein

Hustenstiller lindert Agitation bei Alzheimer

Update Neurologie