Skip to main content
Erschienen in: Acta Neurochirurgica 7/2020

04.03.2020 | Review Article - Tumor - Glioma

Anesthesia management for low-grade glioma awake surgery: a European Low-Grade Glioma Network survey

verfasst von: Jeremy Arzoine, Charlotte Levé, Antonio Pérez-Hick, John Goodden, Fabien Almairac, Sylvie Aubrun, Etienne Gayat, Christian F. Freyschlag, Fabrice Vallée, Emmanuel Mandonnet, Catherine Madadaki, collaborators of the ELGGN

Erschienen in: Acta Neurochirurgica | Ausgabe 7/2020

Einloggen, um Zugang zu erhalten

Abstract

Background

Awake surgery has become a key treatment of diffuse low-grade gliomas (DLGG) and is divided in three main phases: opening, tumor resection – during which the patient needs to be fully awake – and closure. The anesthetic management of awake neurosurgery is a challenge, and there are currently no guidelines.

Objective

The objective of the survey was to explore differences and commonalities regarding the anesthetic management of awake DLGG surgery within the European Low-Grade Glioma Network (ELGGN) centers.

Methods

A form that contained 14 questions about the anesthetic management was sent to 28 centers in May 2015.

Results

Twenty centers responded. During the opening and closing non-awake periods, 56% of teams chose general anesthesia with mechanical ventilation for at least one period (asleep-awake-asleep, SAS protocol), and 44% monitored anesthesia care including sedation without mechanical ventilation (MAC protocol). In case of SAS, all the teams chose intravenous anesthesia, 82% used laryngeal mask instead of endotracheal intubation during the opening sequence, and 71% during closure. Local and regional anesthesia was practiced by all the teams. The most frequently reported cause of pain was dural and cerebral vessels manipulation (77%). Pain management was mostly based on paracetamol (70%) and remifentanil (55%).

Conclusion

Our survey showed that there was an equivalent proportion of centers using SAS or MAC protocols in the anesthetic management of awake surgery in ELGGN centers. The advantages and disadvantages of each anesthesia protocol were reviewed.
Anhänge
Nur mit Berechtigung zugänglich
Literatur
1.
Zurück zum Zitat Capelle L, Fontaine D, Mandonnet E et al (2013) Spontaneous and therapeutic prognostic factors in adult hemispheric World Health Organization grade II gliomas: a series of 1097 cases: clinical article. J Neurosurg 118(6):1157–1168CrossRef Capelle L, Fontaine D, Mandonnet E et al (2013) Spontaneous and therapeutic prognostic factors in adult hemispheric World Health Organization grade II gliomas: a series of 1097 cases: clinical article. J Neurosurg 118(6):1157–1168CrossRef
2.
Zurück zum Zitat Jakola AS, Myrmel KS, Kloster R, Torp SH, Lindal S, Unsgård G, Solheim O (2012) Comparison of a strategy favoring early surgical resection vs a strategy favoring watchful waiting in low-grade gliomas. JAMA 308(18):1881–1888CrossRef Jakola AS, Myrmel KS, Kloster R, Torp SH, Lindal S, Unsgård G, Solheim O (2012) Comparison of a strategy favoring early surgical resection vs a strategy favoring watchful waiting in low-grade gliomas. JAMA 308(18):1881–1888CrossRef
4.
Zurück zum Zitat Roelz R, Strohmaier D, Jabbarli R, Kraeutle R, Egger K, Coenen VA, Weyerbrock A, Reinacher PC (2016) Residual tumor volume as best outcome predictor in low grade Glioma - a nine-years near-randomized survey of surgery vs. Biopsy. Sci Rep 6:32286CrossRef Roelz R, Strohmaier D, Jabbarli R, Kraeutle R, Egger K, Coenen VA, Weyerbrock A, Reinacher PC (2016) Residual tumor volume as best outcome predictor in low grade Glioma - a nine-years near-randomized survey of surgery vs. Biopsy. Sci Rep 6:32286CrossRef
5.
Zurück zum Zitat Smith JS, Chang EF, Lamborn KR, Chang SM, Prados MD, Cha S, Tihan T, Vandenberg S, McDermott MW, Berger MS (2008) Role of extent of resection in the long-term outcome of low-grade hemispheric gliomas. J Clin Oncol 26(8):1338–1345CrossRef Smith JS, Chang EF, Lamborn KR, Chang SM, Prados MD, Cha S, Tihan T, Vandenberg S, McDermott MW, Berger MS (2008) Role of extent of resection in the long-term outcome of low-grade hemispheric gliomas. J Clin Oncol 26(8):1338–1345CrossRef
6.
Zurück zum Zitat Wijnenga MMJ, French PJ, Dubbink HJ et al (2018) The impact of surgery in molecularly defined low-grade glioma: an integrated clinical, radiological, and molecular analysis. Neuro-oncology 20(1):103–112CrossRef Wijnenga MMJ, French PJ, Dubbink HJ et al (2018) The impact of surgery in molecularly defined low-grade glioma: an integrated clinical, radiological, and molecular analysis. Neuro-oncology 20(1):103–112CrossRef
7.
Zurück zum Zitat Brown TJ, Bota DA, van Den Bent MJ et al (2019) Management of low-grade glioma: a systematic review and meta-analysis. Neurooncol Pract 6(4):249–258PubMed Brown TJ, Bota DA, van Den Bent MJ et al (2019) Management of low-grade glioma: a systematic review and meta-analysis. Neurooncol Pract 6(4):249–258PubMed
8.
Zurück zum Zitat European Low-Grade Glioma Network (see appendix for full list of contributors). Electronic address: elggn2006@gmail.com (2017) Evidence-based management of adult patients with diffuse glioma. Lancet Oncol 18(8):e429CrossRef European Low-Grade Glioma Network (see appendix for full list of contributors). Electronic address: elggn2006@gmail.com (2017) Evidence-based management of adult patients with diffuse glioma. Lancet Oncol 18(8):e429CrossRef
9.
Zurück zum Zitat Mandonnet E, Duffau H (2018) An attempt to conceptualize the individual onco-functional balance: why a standardized treatment is an illusion for diffuse low-grade glioma patients. Crit Rev Oncol Hematol 122:83–91CrossRef Mandonnet E, Duffau H (2018) An attempt to conceptualize the individual onco-functional balance: why a standardized treatment is an illusion for diffuse low-grade glioma patients. Crit Rev Oncol Hematol 122:83–91CrossRef
10.
Zurück zum Zitat Soffietti R, Baumert BG, Bello L et al (2010) Guidelines on management of low-grade gliomas: report of an EFNS-EANO task force. Eur J Neurol 17(9):1124–1133CrossRef Soffietti R, Baumert BG, Bello L et al (2010) Guidelines on management of low-grade gliomas: report of an EFNS-EANO task force. Eur J Neurol 17(9):1124–1133CrossRef
11.
Zurück zum Zitat Weller M, van den Bent M, Tonn JC et al (2017) European Association for Neuro-Oncology (EANO) guideline on the diagnosis and treatment of adult astrocytic and oligodendroglial gliomas. Lancet Oncol 18(6):e315–e329CrossRef Weller M, van den Bent M, Tonn JC et al (2017) European Association for Neuro-Oncology (EANO) guideline on the diagnosis and treatment of adult astrocytic and oligodendroglial gliomas. Lancet Oncol 18(6):e315–e329CrossRef
12.
Zurück zum Zitat De Witt Hamer PC, Robles SG, Zwinderman AH, Duffau H, Berger MS (2012) Impact of intraoperative stimulation brain mapping on glioma surgery outcome: a meta-analysis. J Clin Oncol 30(20):2559–2565CrossRef De Witt Hamer PC, Robles SG, Zwinderman AH, Duffau H, Berger MS (2012) Impact of intraoperative stimulation brain mapping on glioma surgery outcome: a meta-analysis. J Clin Oncol 30(20):2559–2565CrossRef
13.
Zurück zum Zitat Hervey-Jumper SL, Berger MS (2016) Maximizing safe resection of low- and high-grade glioma. J Neuro-Oncol 130(2):269–282CrossRef Hervey-Jumper SL, Berger MS (2016) Maximizing safe resection of low- and high-grade glioma. J Neuro-Oncol 130(2):269–282CrossRef
14.
Zurück zum Zitat Meng L, Berger MS, Gelb AW (2015) The potential benefits of awake craniotomy for brain tumor resection: an anesthesiologist’s perspective. J Neurosurg Anesthesiol 27(4):310–317CrossRef Meng L, Berger MS, Gelb AW (2015) The potential benefits of awake craniotomy for brain tumor resection: an anesthesiologist’s perspective. J Neurosurg Anesthesiol 27(4):310–317CrossRef
15.
Zurück zum Zitat Paldor I, Drummond KJ, Awad M, Sufaro YZ, Kaye AH (2016) Is a wake-up call in order? Review of the evidence for awake craniotomy. J Clin Neurosci 23:1–7CrossRef Paldor I, Drummond KJ, Awad M, Sufaro YZ, Kaye AH (2016) Is a wake-up call in order? Review of the evidence for awake craniotomy. J Clin Neurosci 23:1–7CrossRef
16.
Zurück zum Zitat Duffau H (2018) Is non-awake surgery for supratentorial adult low-grade glioma treatment still feasible? Neurosurg Rev 41(1):133–139CrossRef Duffau H (2018) Is non-awake surgery for supratentorial adult low-grade glioma treatment still feasible? Neurosurg Rev 41(1):133–139CrossRef
17.
Zurück zum Zitat Duffau H (2015) Stimulation mapping of white matter tracts to study brain functional connectivity. Nat Rev Neurol 11(5):255–265CrossRef Duffau H (2015) Stimulation mapping of white matter tracts to study brain functional connectivity. Nat Rev Neurol 11(5):255–265CrossRef
18.
Zurück zum Zitat Rofes A, Mandonnet E, Godden J et al (2017) Survey on current cognitive practices within the European Low-Grade Glioma Network: towards a European assessment protocol. Acta Neurochir 159(7):1167–1178CrossRef Rofes A, Mandonnet E, Godden J et al (2017) Survey on current cognitive practices within the European Low-Grade Glioma Network: towards a European assessment protocol. Acta Neurochir 159(7):1167–1178CrossRef
19.
Zurück zum Zitat Vilasboas T, Herbet G, Duffau H (2017) Challenging the myth of right nondominant hemisphere: lessons from Corticosubcortical stimulation mapping in awake surgery and surgical implications. World Neurosurg 103:449–456CrossRef Vilasboas T, Herbet G, Duffau H (2017) Challenging the myth of right nondominant hemisphere: lessons from Corticosubcortical stimulation mapping in awake surgery and surgical implications. World Neurosurg 103:449–456CrossRef
20.
Zurück zum Zitat Stevanovic A, Rossaint R, Veldeman M, Bilotta F, Coburn M (2016) Anaesthesia management for awake craniotomy: systematic review and meta-analysis. PLoS One 11(5):e0156448CrossRef Stevanovic A, Rossaint R, Veldeman M, Bilotta F, Coburn M (2016) Anaesthesia management for awake craniotomy: systematic review and meta-analysis. PLoS One 11(5):e0156448CrossRef
21.
Zurück zum Zitat Ghisi D, Fanelli A, Tosi M, Nuzzi M, Fanelli G (2005) Monitored anesthesia care. Minerva Anestesiol 71(9):533–538PubMed Ghisi D, Fanelli A, Tosi M, Nuzzi M, Fanelli G (2005) Monitored anesthesia care. Minerva Anestesiol 71(9):533–538PubMed
22.
Zurück zum Zitat Garavaglia MM, Das S, Cusimano MD, Crescini C, Mazer CD, Hare GMT, Rigamonti A (2014) Anesthetic approach to high-risk patients and prolonged awake craniotomy using dexmedetomidine and scalp block. J Neurosurg Anesthesiol 26(3):226–233CrossRef Garavaglia MM, Das S, Cusimano MD, Crescini C, Mazer CD, Hare GMT, Rigamonti A (2014) Anesthetic approach to high-risk patients and prolonged awake craniotomy using dexmedetomidine and scalp block. J Neurosurg Anesthesiol 26(3):226–233CrossRef
23.
Zurück zum Zitat Goettel N, Bharadwaj S, Venkatraghavan L, Mehta J, Bernstein M, Manninen PH (2016) Dexmedetomidine vs propofol-remifentanil conscious sedation for awake craniotomy: a prospective randomized controlled trial. Br J Anaesth 116(6):811–821CrossRef Goettel N, Bharadwaj S, Venkatraghavan L, Mehta J, Bernstein M, Manninen PH (2016) Dexmedetomidine vs propofol-remifentanil conscious sedation for awake craniotomy: a prospective randomized controlled trial. Br J Anaesth 116(6):811–821CrossRef
24.
Zurück zum Zitat Eseonu CI, ReFaey K, Garcia O, John A, Quiñones-Hinojosa A, Tripathi P (2017) Awake craniotomy anesthesia: a comparison of the monitored anesthesia care and asleep-awake-asleep techniques. World Neurosurg 104:679–686CrossRef Eseonu CI, ReFaey K, Garcia O, John A, Quiñones-Hinojosa A, Tripathi P (2017) Awake craniotomy anesthesia: a comparison of the monitored anesthesia care and asleep-awake-asleep techniques. World Neurosurg 104:679–686CrossRef
25.
Zurück zum Zitat Mandonnet E, Wager M, Almairac F et al (2017) Survey on current practice within the European Low-Grade Glioma Network: where do we stand and what is the next step? Neurooncol Pract 4(4):241–247PubMedPubMedCentral Mandonnet E, Wager M, Almairac F et al (2017) Survey on current practice within the European Low-Grade Glioma Network: where do we stand and what is the next step? Neurooncol Pract 4(4):241–247PubMedPubMedCentral
26.
Zurück zum Zitat Darlix A, Mandonnet E, Freyschlag CF et al (2019) Chemotherapy and diffuse low-grade gliomas: a survey within the European Low-Grade Glioma Network. Neurooncol Pract 6(4):264–273PubMed Darlix A, Mandonnet E, Freyschlag CF et al (2019) Chemotherapy and diffuse low-grade gliomas: a survey within the European Low-Grade Glioma Network. Neurooncol Pract 6(4):264–273PubMed
27.
Zurück zum Zitat Freyschlag CF, Krieg SM, Kerschbaumer J et al (2018) Imaging practice in low-grade gliomas among European specialized centers and proposal for a minimum core of imaging. J Neuro-Oncol 139(3):699–711CrossRef Freyschlag CF, Krieg SM, Kerschbaumer J et al (2018) Imaging practice in low-grade gliomas among European specialized centers and proposal for a minimum core of imaging. J Neuro-Oncol 139(3):699–711CrossRef
28.
Zurück zum Zitat Meng L, McDonagh DL, Berger MS, Gelb AW (2017) Anesthesia for awake craniotomy: a how-to guide for the occasional practitioner. Can J Anaesth 64(5):517–529CrossRef Meng L, McDonagh DL, Berger MS, Gelb AW (2017) Anesthesia for awake craniotomy: a how-to guide for the occasional practitioner. Can J Anaesth 64(5):517–529CrossRef
29.
Zurück zum Zitat Dilmen OK, Akcil EF, Oguz A, Vehid H, Tunali Y (2017) Comparison of conscious sedation and asleep-awake-asleep techniques for awake craniotomy. J Clin Neurosci 35:30–34CrossRef Dilmen OK, Akcil EF, Oguz A, Vehid H, Tunali Y (2017) Comparison of conscious sedation and asleep-awake-asleep techniques for awake craniotomy. J Clin Neurosci 35:30–34CrossRef
30.
Zurück zum Zitat Burnand C, Sebastian J (2014) Anaesthesia for awake craniotomy. Contin Educ Anaesth Crit Care Pain 14(1):6–11CrossRef Burnand C, Sebastian J (2014) Anaesthesia for awake craniotomy. Contin Educ Anaesth Crit Care Pain 14(1):6–11CrossRef
31.
Zurück zum Zitat Ghazanwy M, Chakrabarti R, Tewari A, Sinha A (2014) Awake craniotomy: a qualitative review and future challenges. Saudi J Anaesth 8(4):529–539CrossRef Ghazanwy M, Chakrabarti R, Tewari A, Sinha A (2014) Awake craniotomy: a qualitative review and future challenges. Saudi J Anaesth 8(4):529–539CrossRef
32.
Zurück zum Zitat Audu PB, Loomba N (2004) Use of cuffed oropharyngeal airway (COPA) for awake intracranial surgery. J Neurosurg Anesthesiol 16(2):144–146CrossRef Audu PB, Loomba N (2004) Use of cuffed oropharyngeal airway (COPA) for awake intracranial surgery. J Neurosurg Anesthesiol 16(2):144–146CrossRef
33.
Zurück zum Zitat Chen CH, Lin CC, Tan PP (1995) Clinical experience of laryngeal mask airway in lateral position during anesthesia. Acta Anaesthesiol Sin 33(1):31–34PubMed Chen CH, Lin CC, Tan PP (1995) Clinical experience of laryngeal mask airway in lateral position during anesthesia. Acta Anaesthesiol Sin 33(1):31–34PubMed
34.
Zurück zum Zitat McCaul CL, Harney D, Ryan M, Moran C, Kavanagh BP, Boylan JF (2005) Airway management in the lateral position: a randomized controlled trial. Anesth Analg 101(4):1221–1225 table of contentsCrossRef McCaul CL, Harney D, Ryan M, Moran C, Kavanagh BP, Boylan JF (2005) Airway management in the lateral position: a randomized controlled trial. Anesth Analg 101(4):1221–1225 table of contentsCrossRef
35.
Zurück zum Zitat Frerk C, Mitchell VS, AF MN, Mendonca C, Bhagrath R, Patel A, O’Sullivan EP, Woodall NM, Ahmad I, Difficult Airway Society intubation guidelines working group (2015) Difficult airway society 2015 guidelines for management of unanticipated difficult intubation in adults. Br J Anaesth 115(6):827–848CrossRef Frerk C, Mitchell VS, AF MN, Mendonca C, Bhagrath R, Patel A, O’Sullivan EP, Woodall NM, Ahmad I, Difficult Airway Society intubation guidelines working group (2015) Difficult airway society 2015 guidelines for management of unanticipated difficult intubation in adults. Br J Anaesth 115(6):827–848CrossRef
36.
Zurück zum Zitat Fontaine D, Almairac F (2017) Pain during awake craniotomy for brain tumor resection. Incidence, causes, consequences and management. Neurochirurgie 63(3):204–207CrossRef Fontaine D, Almairac F (2017) Pain during awake craniotomy for brain tumor resection. Incidence, causes, consequences and management. Neurochirurgie 63(3):204–207CrossRef
37.
Zurück zum Zitat Fontaine D, Almairac F, Santucci S, Fernandez C, Dallel R, Pallud J, Lanteri-Minet M (2018) Dural and pial pain-sensitive structures in humans: new inputs from awake craniotomies. Brain 141(4):1040–1048CrossRef Fontaine D, Almairac F, Santucci S, Fernandez C, Dallel R, Pallud J, Lanteri-Minet M (2018) Dural and pial pain-sensitive structures in humans: new inputs from awake craniotomies. Brain 141(4):1040–1048CrossRef
38.
Zurück zum Zitat Delion M, Terminassian A, Lehousse T, Aubin G, Malka J, N’Guyen S, Mercier P, Menei P (2015) Specificities of awake craniotomy and brain mapping in children for resection of supratentorial tumors in the language area. World Neurosurg 84(6):1645–1652CrossRef Delion M, Terminassian A, Lehousse T, Aubin G, Malka J, N’Guyen S, Mercier P, Menei P (2015) Specificities of awake craniotomy and brain mapping in children for resection of supratentorial tumors in the language area. World Neurosurg 84(6):1645–1652CrossRef
39.
Zurück zum Zitat Frati A, Pesce A, Palmieri M, Iasanzaniro M, Familiari P, Angelini A, Salvati M, Rocco M, Raco A (2019) Hypnosis-aided awake surgery for the management of intrinsic brain tumors versus standard awake-asleep-awake protocol: a preliminary, promising experience. World Neurosurg 121:e882–e891CrossRef Frati A, Pesce A, Palmieri M, Iasanzaniro M, Familiari P, Angelini A, Salvati M, Rocco M, Raco A (2019) Hypnosis-aided awake surgery for the management of intrinsic brain tumors versus standard awake-asleep-awake protocol: a preliminary, promising experience. World Neurosurg 121:e882–e891CrossRef
40.
Zurück zum Zitat Zemmoura I, Fournier E, El-Hage W, Jolly V, Destrieux C, Velut S (2016) Hypnosis for awake surgery of low-grade gliomas: description of the method and psychological assessment. Neurosurgery 78(1):53–61CrossRef Zemmoura I, Fournier E, El-Hage W, Jolly V, Destrieux C, Velut S (2016) Hypnosis for awake surgery of low-grade gliomas: description of the method and psychological assessment. Neurosurgery 78(1):53–61CrossRef
Metadaten
Titel
Anesthesia management for low-grade glioma awake surgery: a European Low-Grade Glioma Network survey
verfasst von
Jeremy Arzoine
Charlotte Levé
Antonio Pérez-Hick
John Goodden
Fabien Almairac
Sylvie Aubrun
Etienne Gayat
Christian F. Freyschlag
Fabrice Vallée
Emmanuel Mandonnet
Catherine Madadaki
collaborators of the ELGGN
Publikationsdatum
04.03.2020
Verlag
Springer Vienna
Erschienen in
Acta Neurochirurgica / Ausgabe 7/2020
Print ISSN: 0001-6268
Elektronische ISSN: 0942-0940
DOI
https://doi.org/10.1007/s00701-020-04274-0

Weitere Artikel der Ausgabe 7/2020

Acta Neurochirurgica 7/2020 Zur Ausgabe

Leitlinien kompakt für die Neurologie

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Update Neurologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.