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Archives of Virology

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01.11.2009 | Brief Report

Prevalence of human metapneumovirus in hospitalized children with respiratory tract infections in Tianjin, China

verfasst von: Xiao-yan Li, Jin-ying Chen, Mei Kong, Xu Su, Yan-ping Yi, Ming Zou, Hua Zhang

Erschienen in: Archives of Virology | Ausgabe 11/2009

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Abstract

Human metapneumovirus (hMPV) has recently been recognized as an important respiratory pathogen, especially in children. At present, our understanding of the characteristics of hMPV from China is very limited. Nasopharyngeal aspirates were taken from 310 hospitalized pediatric patients. Twenty (6.5%) of them were infected with hMPV, and they all developed pneumonia. Sixty five percent (13/20) of the cases were under 12 months. Phylogenetic analysis of F gene fragments indicated that three sub-genotypes of hMPV(A2a/A2b, B1,B2) circulated in Tianjin and A2b was the predominant subtype. The Vero-E6 cell line was better than LLC-MK2 for hMPV isolation. Three hMPV strains were successfully isolated using the Vero-E6 cell line.

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Titel: Prevalence of human metapneumovirus in hospitalized children with respiratory tract infections in Tianjin, China
verfasst von: Xiao-yan Li
Jin-ying Chen
Mei Kong
Xu Su
Yan-ping Yi
Ming Zou
Hua Zhang
Publikationsdatum: 01.11.2009
Verlag: Springer Vienna
Erschienen in: Archives of Virology / Ausgabe 11/2009
Print ISSN: 0304-8608
Elektronische ISSN: 1432-8798
DOI: https://doi.org/10.1007/s00705-009-0492-8

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