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Archives of Virology

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01.01.2015 | Annotated Sequence Record

Recombination in truncated genome sequences of porcine circovirus type 2

verfasst von: Libin Wen, Fengzhi Wang, Kongwang He, Bin Li, Xiaomin Wang, Rongli Guo, Jianping Xie

Erschienen in: Archives of Virology | Ausgabe 1/2015

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Abstract

Porcine circovirus type 2 (PCV2) is the causal agent of a serious disease found in pigs. Here, we report the first detection of truncated genome sequences of PCV2 strain ZJ-R, with the genomic region encoding part of Rep and Cap with a nonviral insertion. To our knowledge, the genome of ZJ-R represents the first PCV2 DNA with a coding insertion. The PCV2 ZJ-R genome is 694 nucleotides long and has two main open reading frames. The whole genome sequence of ZJ-R may facilitate further study of the origin and evolution of PCV2.

Cadar D, Cságola A, Lorincz M, Tombácz K, Spînu M, Tuboly T (2012) Detection of natural inter- and intra-genotype recombination events revealed by cap gene analysis and decreasing prevalence of PCV2 in wild boars. Infect Genet Evol 12(2):420–427CrossRefPubMed

Cai L, Ni J, Xia Y, Zi Z, Ning K, Qiu P, Li X, Wang B, Liu Q, Hu D, Yu X, Zhou Z, Zhai X, Han X, Tian K (2012) Identification of an emerging recombinant cluster in porcine circovirus type 2. Virus Res 165(1):95–102CrossRefPubMed

Cheung AK (2003) Transcriptional analysis of porcine circovirus type 2. Virology 305(1):168–180CrossRefPubMed

Duffy S, Shackelton LA, Holmes EC (2008) Rates of evolutionary change in viruses: patterns and determinants. Nat Rev Genet 9(4):267–276CrossRefPubMed

Hamel AL, Lin LL, Nayar GP (1998) Nucleotide sequence of porcine circovirus associated with postweaning multisystemic wasting syndrome in pigs. J Virol 72(6):5262–5267PubMedCentralPubMed

Harding JC (1996) Post-weaning multisystemic wasting syndrome (PMWS): preliminary epidemiology and clinical presentation. In: Proceedings of the 27th Annual Meeting of the Western Canadian Association of Swine Veterinarians, Saskatoon, Saskatchewan, Canada, p 21

He J, Cao J, Zhou N, Jin Y, Wu J, Zhou J (2013) Identification and functional analysis of the novel ORF4 protein encoded by porcine circovirus type 2. J Virol 87(3):1420–1429PubMedCentralCrossRefPubMed

Liu J, Chen I, Du Q, Chua H, Kwang J (2006) The ORF3 protein of porcine circovirus type 2 is involved in viral pathogenesis in vivo. J Virol 80:5065–5073PubMedCentralCrossRefPubMed

Liu J, Chen I, Kwang J (2005) Characterization of a previously unidentified viral protein in porcine circovirus type 2-infected cells and its role in virus-induced apoptosis. J Virol 79:8262–8274PubMedCentralCrossRefPubMed

10.

Luo W, Zhao D, Yu XL, Ge M, Li RC, Jiang DL (2013) Small-sized circular genomes similar to genome of porcine circovirus 2. Genome Announc 1(2):e0009313CrossRefPubMed

11.

Mankertz A, Mankertz J, Wolf K, Buhk HJ (1998) Identification of a protein essential for replication of porcine circovirus. J Gen Virol 79(2):381–384PubMed

12.

Nawagitgul P, Harms PA, Morozov I, Thacker BJ, Sorden SD, Lekcharoensuk C, Paul PS (2002) Modified indirect porcine circovirus (PCV) type 2-based and recombinant capsid protein (ORF2)-based enzyme-linked immunosorbent assays for detection of antibodies to PCV. Clin Diagn Lab Immun 9(1):33–40

13.

Nawagitgul P, Morozov I, Bolin SR, Harms PA, Sorden SD, Paul PS (2000) Open reading frame 2 of porcine circovirus type 2 encodes a major capsid protein. J Gen Virol 81(9):2281–2287PubMed

14.

Pensaert MB, Sanchez RE, Jr, Nauwynck HJ (2001) Transmission of porcine circovirus type 2 from the sow to the litter. In: Proceedings of the international conference on ssDNA viruses of plants, birds and primates, Saint Malo, France, p 84

15.

Pesch S, Schmidt U, Ohlinger VF (2000) Proliferative necrotizing pneumonia (PNP) is a result of coinfection with porcine reproductive and respiratory syndrome virus (PRRSV) and porcine circovirus type 2 (PCV-2). In: Proceedings of the 16th international pig veterinary society congress, Melbourne, Australia, p 581

16.

Segalés J (2012) Porcine circovirus type 2 (PCV2) infections: clinical signs, pathology and laboratory diagnosis. Virus Res 164:10–19CrossRefPubMed

17.

Segalés J, Domingo M, Latimer KS (1998) Porcine circovirus is present in cases of porcine dermatitis and nephropathy syndrome (PDNS). In: Proceedings of the 15th international pig veterinary society congress, Birmingham, England, p 215

18.

Segalés J, Olvera J, Grau-Roma L, Charreyre C, Nauwynck H, Larsen L, Dupont K, McCullough K, Ellis J, Krakowka S, Mankertz A, Fredholm M, Fossum C, Timmusk S, Stockhofe-Zurwieden N, Beattie V, Armstrong D, Grassland B, Baekbo P, Allan G (2008) PCV2 genotype definition and nomenclature. Vet Rec 162:867–868CrossRefPubMed

19.

Wen L, He K, Li B, Wang X, Guo R, Yu Z, Mao A, Ni Y, Zhang X, Zhou J, Lv L, Jiang J (2012) In vitro and in vivo isolation of a novel rearranged porcine circovirus type 2. J Virol 86(23):13120PubMedCentralCrossRefPubMed

20.

Wen L, He K, Ni Y, Zhang X, Li B, Wang X, Guo R, Yu Z, Mao A, Zhou J, Lv L, Jiang J (2012) Complete genome sequence of the rearranged porcine circovirus type 2. J Virol 86(10):5963PubMedCentralCrossRefPubMed

21.

Wen L, He K, Ni Y, Zhang X, Li B, Wang X, Guo R, Yu Z, Mao A, Zhou J, Lv L, Jiang J (2012) In vitro intragenomic rearrangement of porcine circovirus type 2. J Virol 86(16):8911PubMedCentralCrossRefPubMed

22.

Wen L, He K, Xiao Q, Yu Z, Mao A, Ni Y, Zhang X, Li B, Wang X, Guo R, Zhou J, Lv L, Jiang J (2012) A novel porcine circovirus-like agent P1 is associated with wasting syndromes in pigs. PLoS One 7(8):e41565PubMedCentralCrossRefPubMed

23.

Wen L, He K, Yang H, Ni Y, Zhang X, Guo R, Pan Q (2008) Complete nucleotide sequence of a novel porcine circovirus-like agent and its infectivity in vitro. Sci China C Life Sci 51(5):453–458CrossRefPubMed

24.

Wen L, He K, Yang H, Yu Z, Mao A, Zhong S, Ni Y, Zhang X, Li B, Wang X, Zhou J, Guo R, Lv L, Jiang J (2011) Prevalence of porcine circovirus-like agent P1 in Jiangsu, China. Virol J 8:543–547PubMedCentralCrossRefPubMed

25.

Wen L, He K, Yu Z, Mao A, Ni Y, Zhang X, Guo RL, Li B, Wang X, Zhou J, Lv L (2012) Complete genome sequence of a novel porcine circovirus-like agent. J Virol 86(1):639PubMedCentralCrossRefPubMed

Titel: Recombination in truncated genome sequences of porcine circovirus type 2
verfasst von: Libin Wen
Fengzhi Wang
Kongwang He
Bin Li
Xiaomin Wang
Rongli Guo
Jianping Xie
Publikationsdatum: 01.01.2015
Verlag: Springer Vienna
Erschienen in: Archives of Virology / Ausgabe 1/2015
Print ISSN: 0304-8608
Elektronische ISSN: 1432-8798
DOI: https://doi.org/10.1007/s00705-014-2242-9

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Recombination in truncated genome sequences of porcine circovirus type 2

Abstract

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