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Erschienen in: Die Onkologie 9/2011

01.09.2011 | Außer der Reihe

Psychoneuroimmunologie und Krebs

Neue Ergebnisse zu psychosozialen Einflüssen auf Tumorerkrankungen

verfasst von: Dr. J. Hefner, H. Csef

Erschienen in: Die Onkologie | Ausgabe 9/2011

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Zusammenfassung

Aktuelle Arbeiten deuten auf einen Einfluss psychischer Faktoren auf den Krankheitsverlauf bei Krebs hin. Bei der Suche nach den zugrunde liegenden Mechanismen konzentrierte sich die psychoneuroimmunologische Forschung auf den Einfluss von psychischer Belastung bzw. von Stresshormonen auf die Wechselwirkungen von Immunsystem und Tumorzelle. Dabei wurden natürliche Killer (NK)-Zellen bisher am umfangreichsten untersucht. Doch die Ergebnisse sind inkonsistent, und so führte dies – in Anlehnung an die onkologische Forschung – zu einer Verschiebung des Fokus hin zu Untersuchungen des „tumor microenvironment“. Hier wurden in den letzten Jahren zu einzelnen Tumorentitäten neue Erkenntnisse gewonnen, die durch Gemeinsamkeiten der Pathophysiologie auch für die Onkologie bedeutsam sind. Weiterhin unklar bleibt dabei die Relevanz der Befunde für den Krankheitsverlauf bei Krebs.
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Metadaten
Titel
Psychoneuroimmunologie und Krebs
Neue Ergebnisse zu psychosozialen Einflüssen auf Tumorerkrankungen
verfasst von
Dr. J. Hefner
H. Csef
Publikationsdatum
01.09.2011
Verlag
Springer-Verlag
Erschienen in
Die Onkologie / Ausgabe 9/2011
Print ISSN: 2731-7226
Elektronische ISSN: 2731-7234
DOI
https://doi.org/10.1007/s00761-011-2077-x

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