Skip to main content
Erschienen in: Clinical Oral Investigations 4/2014

01.05.2014 | Original Article

Incidental findings on cone beam computed tomography scans in cleft lip and palate patients

verfasst von: Mette A. R. Kuijpers, Andrzej Pazera, Ronald J. Admiraal, Stefaan J. Bergé, Arjan Vissink, Pawel Pazera

Erschienen in: Clinical Oral Investigations | Ausgabe 4/2014

Einloggen, um Zugang zu erhalten

Abstract

Objectives

Cone beam computed tomography (CBCT) is frequently used in treatment planning for alveolar bone grafting (ABG) and orthognathic surgery in patients with cleft lip and palate (CLP). CBCT images may depict coincident findings. The aim of this study was to assess the prevalence of incidental findings on CBCT scans in CLP patients.

Subjects and methods

Initial CBCTs taken from consecutive patients (n = 187; mean age 11.7 years, range 6.9–45) with a non-syndromic orofacial cleft from January 2006 until June 2012 were systematically evaluated. Twenty-eight patients (mean age 19.3 years, range 13.2–30.9) had been subjected to ABG before their first CBCT was taken; 61 patients had a CBCT before and after ABG. Sinuses, nasopharynx, oropharynx, throat, skull, vertebrae, temporomandibular joint (TMJ), maxilla and mandible were checked for incidental findings.

Results

On 95.1 % of the CBCTs, incidental findings were found. The most prevalent were airway/sinus findings (56.1 %), followed by dental problems, e.g. missing teeth (52 %), nasal septum deviation (34 %), middle ear and mastoid opacification, suggestive for otitis media (10 %) and (chronic) mastoiditis (9 %), abnormal TMJ anatomy (4.9 %) and abnormal vertebral anatomy (1.6 %). In the 28 patients whose first CBCT was taken at least 2 years after ABG, bone was still present in the reconstructed cleft area except in 2 out of 12 patients with a bilateral CLP. The ABG donor site (all bone grafts were taken from the chin area) was still recognizable in over 50 % of the patients. Based on the CBCT findings, 10 % of the patients were referred for further diagnosis and 9 % for further treatment related to dental problems.

Conclusion

Incidental findings are common on CBCTs. Compared with the literature, CLP patients have more dental, nasal and ear problems. Thus, whenever a CBCT is available, this scan should be reviewed by all specialists in the CLP team focusing on their specific background knowledge concerning symptoms and treatment of these patients.

Clinical relevance

The high number of findings indicates that CBCT imaging is a helpful tool in the treatment of CLP patients not only related to alveolar bone grafting and orthognathic surgery but it also provides diagnostic information for almost all specialties involved in CLP treatment.
Literatur
2.
Zurück zum Zitat Rege IC, Sousa TO, Leles CR, Mendonça EF (2012) Occurrence of maxillary sinus abnormalities detected by cone beam CT in asymptomatic patients. BMC Oral Health 10:12–30 Rege IC, Sousa TO, Leles CR, Mendonça EF (2012) Occurrence of maxillary sinus abnormalities detected by cone beam CT in asymptomatic patients. BMC Oral Health 10:12–30
3.
Zurück zum Zitat Price JB, Thaw KL, Tyndall DA, Ludlow JB, Padilla RJ (2012) Incidental findings from cone beam computed tomography of the maxillofacial region: a descriptive retrospective study. Clin Oral Implants Res 23:1261–1268PubMedCrossRef Price JB, Thaw KL, Tyndall DA, Ludlow JB, Padilla RJ (2012) Incidental findings from cone beam computed tomography of the maxillofacial region: a descriptive retrospective study. Clin Oral Implants Res 23:1261–1268PubMedCrossRef
4.
Zurück zum Zitat Plooij JM, Maal TJ, Haers P, Borstlap WA, Kuijpers-Jagtman AM, Bergé SJ (2011) Digital three-dimensional image fusion processes for planning and evaluating orthodontics and orthognathic surgery. A systematic review. Int J Oral Maxillofac Surg 40:341–352PubMedCrossRef Plooij JM, Maal TJ, Haers P, Borstlap WA, Kuijpers-Jagtman AM, Bergé SJ (2011) Digital three-dimensional image fusion processes for planning and evaluating orthodontics and orthognathic surgery. A systematic review. Int J Oral Maxillofac Surg 40:341–352PubMedCrossRef
5.
Zurück zum Zitat Timmerman K, Vander Poorten V, Desloovere C, Debruyne F (2006) The middle ear in cleft palate patients in their early teens: a literature study and preliminary file study. B-ENT 2(Suppl 4):95–101 Timmerman K, Vander Poorten V, Desloovere C, Debruyne F (2006) The middle ear in cleft palate patients in their early teens: a literature study and preliminary file study. B-ENT 2(Suppl 4):95–101
6.
Zurück zum Zitat Sheahan P, Miller I, Sheahan JN, Earley MJ, Blayney AW (2003) Incidence and outcome of middle ear disease in cleft lip and/or cleft palate. Int J Pediatr Otorhinolaryngol 67:785–793PubMedCrossRef Sheahan P, Miller I, Sheahan JN, Earley MJ, Blayney AW (2003) Incidence and outcome of middle ear disease in cleft lip and/or cleft palate. Int J Pediatr Otorhinolaryngol 67:785–793PubMedCrossRef
7.
Zurück zum Zitat Flynn T, Lohmander A, Moller C, Magnusson L (2013) A longitudinal study of hearing and middle ear status in adolescents with cleft lip and palate. Laryngoscope 23:1374–1380CrossRef Flynn T, Lohmander A, Moller C, Magnusson L (2013) A longitudinal study of hearing and middle ear status in adolescents with cleft lip and palate. Laryngoscope 23:1374–1380CrossRef
8.
Zurück zum Zitat Hocevar-Boltezar I, Jarc A, Kozelj V (2006) Ear, nose and voice problems in children with orofacial clefts. J Laryngol Otol 120:276–281PubMedCrossRef Hocevar-Boltezar I, Jarc A, Kozelj V (2006) Ear, nose and voice problems in children with orofacial clefts. J Laryngol Otol 120:276–281PubMedCrossRef
9.
Zurück zum Zitat Polder BJ, Van ‘t Hof MA, Van der Linden FP, Kuijpers-Jagtman AM (2004) A meta-analysis of the prevalence of dental agenesis of permanent teeth. Commun Dent Oral Epidemiol 32:217–226CrossRef Polder BJ, Van ‘t Hof MA, Van der Linden FP, Kuijpers-Jagtman AM (2004) A meta-analysis of the prevalence of dental agenesis of permanent teeth. Commun Dent Oral Epidemiol 32:217–226CrossRef
10.
Zurück zum Zitat Tannure PN, Oliveira CA, Maia LC, Vieira AR, Granjeiro JM, de Castro CM (2012) Prevalence of dental anomalies in nonsyndromic individuals with cleft lip and palate: a systematic review and meta-analysis. Cleft Palate Craniofac J 49:194–200PubMedCrossRef Tannure PN, Oliveira CA, Maia LC, Vieira AR, Granjeiro JM, de Castro CM (2012) Prevalence of dental anomalies in nonsyndromic individuals with cleft lip and palate: a systematic review and meta-analysis. Cleft Palate Craniofac J 49:194–200PubMedCrossRef
11.
Zurück zum Zitat Tortora C, Meazzini MC, Garattini G, Brusati R (2008) Prevalence of abnormalities in dental structure, position, and eruption pattern in a population of unilateral and bilateral cleft lip and palate patients. Cleft Palate Craniofac J 45:154–162PubMedCrossRef Tortora C, Meazzini MC, Garattini G, Brusati R (2008) Prevalence of abnormalities in dental structure, position, and eruption pattern in a population of unilateral and bilateral cleft lip and palate patients. Cleft Palate Craniofac J 45:154–162PubMedCrossRef
12.
Zurück zum Zitat Pette GA, Norkin FJ, Ganeles J, Hardigan P, Lask E, Zfaz S, Parker W (2012) Incidental findings from a retrospective study of 318 cone beam computed tomography consultation reports. Int J Oral Maxillofac Implants 27:595–603PubMed Pette GA, Norkin FJ, Ganeles J, Hardigan P, Lask E, Zfaz S, Parker W (2012) Incidental findings from a retrospective study of 318 cone beam computed tomography consultation reports. Int J Oral Maxillofac Implants 27:595–603PubMed
13.
Zurück zum Zitat Pazera P, Bornstein MM, Pazera A, Sendi P, Katsaros C (2011) Incidental maxillary sinus findings in orthodontic patients: a radiographic analysis using cone-beam computed tomography (CBCT). Orthod Craniofacial Res 14:17–24CrossRef Pazera P, Bornstein MM, Pazera A, Sendi P, Katsaros C (2011) Incidental maxillary sinus findings in orthodontic patients: a radiographic analysis using cone-beam computed tomography (CBCT). Orthod Craniofacial Res 14:17–24CrossRef
14.
Zurück zum Zitat Cha JY, Mah J, Sinclair P (2007) Incidental findings in the maxillofacial area with 3-dimensional cone-beam imaging. Am J Orthod Dentofac Orthop 132:7–14CrossRef Cha JY, Mah J, Sinclair P (2007) Incidental findings in the maxillofacial area with 3-dimensional cone-beam imaging. Am J Orthod Dentofac Orthop 132:7–14CrossRef
15.
Zurück zum Zitat Cağlayan F, Tozoğlu U (2012) Incidental findings in the maxillofacial region detected by cone beam CT. Diagn Interv Radiol 18:159–163PubMed Cağlayan F, Tozoğlu U (2012) Incidental findings in the maxillofacial region detected by cone beam CT. Diagn Interv Radiol 18:159–163PubMed
16.
Zurück zum Zitat Gracco A, Incerti Parenti S, Ioele C, Alessandri Bonetti G, Stellini E (2012) Prevalence of incidental maxillary sinus findings in Italian orthodontic patients: a retrospective cone-beam computed tomography study. Korean J Orthod 42:329–334PubMedCentralPubMedCrossRef Gracco A, Incerti Parenti S, Ioele C, Alessandri Bonetti G, Stellini E (2012) Prevalence of incidental maxillary sinus findings in Italian orthodontic patients: a retrospective cone-beam computed tomography study. Korean J Orthod 42:329–334PubMedCentralPubMedCrossRef
17.
Zurück zum Zitat Ritter L, Lutz J, Neugebauer J, Scheer M, Dreiseidler T, Zinser MJ, Rothamel D, Mischkowski RA (2011) Prevalence of pathologic findings in the maxillary sinus in cone-beam computerized tomography. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 111:634–640PubMedCrossRef Ritter L, Lutz J, Neugebauer J, Scheer M, Dreiseidler T, Zinser MJ, Rothamel D, Mischkowski RA (2011) Prevalence of pathologic findings in the maxillary sinus in cone-beam computerized tomography. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 111:634–640PubMedCrossRef
18.
Zurück zum Zitat Carter L, Farman AG, Geist J, Scarfe WC, Angelopoulos C, Nair MK, Hildebolt CF, Tyndall D, Shrout (2008) American Academy of Oral and Maxillofacial Radiology executive opinion statement on performing and interpreting diagnostic cone beam computed tomography. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 106:561–562PubMedCrossRef Carter L, Farman AG, Geist J, Scarfe WC, Angelopoulos C, Nair MK, Hildebolt CF, Tyndall D, Shrout (2008) American Academy of Oral and Maxillofacial Radiology executive opinion statement on performing and interpreting diagnostic cone beam computed tomography. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 106:561–562PubMedCrossRef
19.
Zurück zum Zitat Horner K, Islam M, Flygare L, Tsiklakis K, Whaites E (2009) Basic principles for use of dental cone beam computed tomography: consensus guidelines of the European Academy of Dental and Maxillofacial Radiology. Dentomaxillofac Radiol 38:187–195PubMedCrossRef Horner K, Islam M, Flygare L, Tsiklakis K, Whaites E (2009) Basic principles for use of dental cone beam computed tomography: consensus guidelines of the European Academy of Dental and Maxillofacial Radiology. Dentomaxillofac Radiol 38:187–195PubMedCrossRef
20.
Zurück zum Zitat Landis JR, Koch GG (1977) The measurement of observer agreement for categorical data. Biometrics 33:159–174PubMedCrossRef Landis JR, Koch GG (1977) The measurement of observer agreement for categorical data. Biometrics 33:159–174PubMedCrossRef
21.
Zurück zum Zitat Miyamoto J, Nagasao T, Nakajima T, Ogata H (2007) Evaluation of cleft lip bony depression of piriform margin and nasal deformity with cone beam computed tomography: “retruded-like” appearance and anteroposterior position of the alar base”. Plast Reconstr Surg 120:1612–1620PubMedCrossRef Miyamoto J, Nagasao T, Nakajima T, Ogata H (2007) Evaluation of cleft lip bony depression of piriform margin and nasal deformity with cone beam computed tomography: “retruded-like” appearance and anteroposterior position of the alar base”. Plast Reconstr Surg 120:1612–1620PubMedCrossRef
22.
Zurück zum Zitat Miyamoto J, Nakajima T (2010) Anthropometric evaluation of complete unilateral cleft lip nose with cone beam CT in early childhood. J Plast Reconstr Aesthet Surg 63:9–14PubMedCrossRef Miyamoto J, Nakajima T (2010) Anthropometric evaluation of complete unilateral cleft lip nose with cone beam CT in early childhood. J Plast Reconstr Aesthet Surg 63:9–14PubMedCrossRef
23.
Zurück zum Zitat Nagasao T, Miyamoto J, Hikosaka M, Yoshikawa K, Ishii N, Nakajima T (2008) A new method to quantify subtle morphological deformities in nasal profile curvatures and its application for analysis of unilateral cleft lip noses. J Craniomaxillofac Surg 36:321–334PubMedCrossRef Nagasao T, Miyamoto J, Hikosaka M, Yoshikawa K, Ishii N, Nakajima T (2008) A new method to quantify subtle morphological deformities in nasal profile curvatures and its application for analysis of unilateral cleft lip noses. J Craniomaxillofac Surg 36:321–334PubMedCrossRef
24.
Zurück zum Zitat Oberoi S, Gill P, Chigurupati R, Hoffman WY, Hatcher DC, Vargervik K (2010) Three-dimensional assessment of the eruption path of the canine in individuals with bone-grafted alveolar clefts using cone beam computed tomography. Cleft Palate Craniofac J 47:507–512PubMedCrossRef Oberoi S, Gill P, Chigurupati R, Hoffman WY, Hatcher DC, Vargervik K (2010) Three-dimensional assessment of the eruption path of the canine in individuals with bone-grafted alveolar clefts using cone beam computed tomography. Cleft Palate Craniofac J 47:507–512PubMedCrossRef
25.
Zurück zum Zitat Garib DG, Yatabe MS, Ozawa TO, Da Silva Filho OG (2012) Alveolar bone morphology in patients with bilateral complete cleft lip and palate in the mixed dentition: cone beam computed tomography evaluation.”. Cleft Palate Craniofac J 49:208–214PubMedCrossRef Garib DG, Yatabe MS, Ozawa TO, Da Silva Filho OG (2012) Alveolar bone morphology in patients with bilateral complete cleft lip and palate in the mixed dentition: cone beam computed tomography evaluation.”. Cleft Palate Craniofac J 49:208–214PubMedCrossRef
26.
Zurück zum Zitat Li F, Wang JG (2011) Measurement of tooth length of upper canines in complete unilateral cleft lip and palate patients with cone-beam computed tomography. Hua Xi Kou Qiang Yi Xue Za Zhi 29(161–163):167 Li F, Wang JG (2011) Measurement of tooth length of upper canines in complete unilateral cleft lip and palate patients with cone-beam computed tomography. Hua Xi Kou Qiang Yi Xue Za Zhi 29(161–163):167
27.
Zurück zum Zitat Padricelli G, Monsurro A, Grassia V, Perillo L (2012) The frequency of dental anomalies in subjects with cleft lip and palate. Mondo Ortodontico 37:46–55CrossRef Padricelli G, Monsurro A, Grassia V, Perillo L (2012) The frequency of dental anomalies in subjects with cleft lip and palate. Mondo Ortodontico 37:46–55CrossRef
28.
Zurück zum Zitat Cheung T, Oberoi S (2012) Three dimensional assessment of the pharyngeal airway in individuals with non-syndromic cleft lip and palate. PLoS ONE 7:e43405PubMedCentralPubMedCrossRef Cheung T, Oberoi S (2012) Three dimensional assessment of the pharyngeal airway in individuals with non-syndromic cleft lip and palate. PLoS ONE 7:e43405PubMedCentralPubMedCrossRef
29.
Zurück zum Zitat Yoshihara M, Terajima M, Yanagita N, Hyakutake H, Kanomi R, Kitahara T, Takahashi I (2012) Three-dimensional analysis of the pharyngeal airway morphology in growing Japanese girls with and without cleft lip and palate. Am J Orthod Dentofac Orthop 141:S92–S101CrossRef Yoshihara M, Terajima M, Yanagita N, Hyakutake H, Kanomi R, Kitahara T, Takahashi I (2012) Three-dimensional analysis of the pharyngeal airway morphology in growing Japanese girls with and without cleft lip and palate. Am J Orthod Dentofac Orthop 141:S92–S101CrossRef
30.
Zurück zum Zitat Zhou W, Li W, Lin J, Liu D, Xie X, Zhang Z (2012) Tooth lengths of the permanent upper incisors in patients with cleft lip and palate determined with cone beam computed tomography. Cleft Palate Craniofac J 50:88–95PubMedCrossRef Zhou W, Li W, Lin J, Liu D, Xie X, Zhang Z (2012) Tooth lengths of the permanent upper incisors in patients with cleft lip and palate determined with cone beam computed tomography. Cleft Palate Craniofac J 50:88–95PubMedCrossRef
31.
Zurück zum Zitat Stefanini R, Tufik S, Soares MC, Haddad FL, Bittencourt LR, Santos-Silva R, Gregorio LC (2012) Systematic evaluation of the upper airway in the adult population of São Paulo, Brazil. Otolaryngol Head Neck Surg 146:757–763PubMedCrossRef Stefanini R, Tufik S, Soares MC, Haddad FL, Bittencourt LR, Santos-Silva R, Gregorio LC (2012) Systematic evaluation of the upper airway in the adult population of São Paulo, Brazil. Otolaryngol Head Neck Surg 146:757–763PubMedCrossRef
32.
Zurück zum Zitat Yiğit O, Acioğlu E, Cakir ZA, Sişman AS, Barut AY (2010) Concha bullosa and septal deviation. Eur Arch Otorhinolaryngol 267:1397–1401PubMedCrossRef Yiğit O, Acioğlu E, Cakir ZA, Sişman AS, Barut AY (2010) Concha bullosa and septal deviation. Eur Arch Otorhinolaryngol 267:1397–1401PubMedCrossRef
33.
Zurück zum Zitat Reitzen SD, Chung W, Shah AR (2011) Nasal septal deviation in the pediatric and adult populations. Ear Nose Throat J 90:112–115PubMed Reitzen SD, Chung W, Shah AR (2011) Nasal septal deviation in the pediatric and adult populations. Ear Nose Throat J 90:112–115PubMed
34.
Zurück zum Zitat Dik EA, de Ruiter AP, van der Bilt A, Koole R (2010) Effect on the contour of bone and soft tissue one year after harvesting chin bone for alveolar cleft repair. Int J Oral Maxillofac Surg 39:962–967PubMedCrossRef Dik EA, de Ruiter AP, van der Bilt A, Koole R (2010) Effect on the contour of bone and soft tissue one year after harvesting chin bone for alveolar cleft repair. Int J Oral Maxillofac Surg 39:962–967PubMedCrossRef
Metadaten
Titel
Incidental findings on cone beam computed tomography scans in cleft lip and palate patients
verfasst von
Mette A. R. Kuijpers
Andrzej Pazera
Ronald J. Admiraal
Stefaan J. Bergé
Arjan Vissink
Pawel Pazera
Publikationsdatum
01.05.2014
Verlag
Springer Berlin Heidelberg
Erschienen in
Clinical Oral Investigations / Ausgabe 4/2014
Print ISSN: 1432-6981
Elektronische ISSN: 1436-3771
DOI
https://doi.org/10.1007/s00784-013-1095-z

Weitere Artikel der Ausgabe 4/2014

Clinical Oral Investigations 4/2014 Zur Ausgabe

Newsletter

Bestellen Sie unseren kostenlosen Newsletter Update Zahnmedizin und bleiben Sie gut informiert – ganz bequem per eMail.