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Erschienen in: Clinical Oral Investigations 8/2016

13.01.2016 | Original Article

Fluoride toothpaste supplemented with sodium hexametaphosphate reduces enamel demineralization in vitro

verfasst von: Danielle Mendes da Camara, Juliano Pelim Pessan, Tamires Melo Francati, José Antonio Santos Souza, Marcelle Danelon, Alberto Carlos Botazzo Delbem

Erschienen in: Clinical Oral Investigations | Ausgabe 8/2016

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Abstract

Objective

The aim of this study was to evaluate the effect of fluoride dentifrices combined with sodium hexametaphosphate (HMP) on enamel demineralization in vitro.

Material and methods

Enamel bovine blocks were selected by initial surface hardness (SHi) and then divided into five experimental groups (n = 12): placebo (without fluoride and without HMP); 1100 ppm F (1100F); and 1100F associated with HMP at 0.5 % (1100HMP0.5%), 1 % (1100HMP1%), and 2 % of HMP (1100HMP2%). Blocks were submitted to five pH cycles (demineralizing/remineralizing solutions) at 37 °C. After pH cycling, final surface hardness (SHf), percentage of surface hardness loss (%SH), integrated differential hardness (ΔIH), integrated loss of subsurface hardness (ΔKHN), and enamel firmly bound fluoride (F) were determined. Data were submitted to one-way ANOVA, followed by Student–Newman–Keuls test (p < 0.05).

Results

Significant differences were observed among all groups regarding %SH and ΔKHN. 1100HMP1% promoted the lowest mineral loss among all groups (p < 0.001), and led to significantly lower demineralization in the deeper regions of the subsurface lesion when compared with the other HMP-containing toothpastes (p < 0.001). Significantly higher mineral loss was observed for 1100HMP2% when compared to the other fluoridated dentifrices, mainly in the outer part of the lesion (p < 0.001). Enamel F uptake was similar for 1100F and 1100HMP1% but significantly reduced for other HMP concentrations.

Conclusion

The supplementation of a 1100-ppm F dentifrice with 1 % HMP promoted a higher inhibitory effect against enamel demineralization when compared to a dentifrice containing the same amount of fluoride in vitro.

Clinical relevance

This dentifrice could potentially be indicated to patients at high risk of caries.
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Metadaten
Titel
Fluoride toothpaste supplemented with sodium hexametaphosphate reduces enamel demineralization in vitro
verfasst von
Danielle Mendes da Camara
Juliano Pelim Pessan
Tamires Melo Francati
José Antonio Santos Souza
Marcelle Danelon
Alberto Carlos Botazzo Delbem
Publikationsdatum
13.01.2016
Verlag
Springer Berlin Heidelberg
Erschienen in
Clinical Oral Investigations / Ausgabe 8/2016
Print ISSN: 1432-6981
Elektronische ISSN: 1436-3771
DOI
https://doi.org/10.1007/s00784-015-1707-x

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