Abstract
Aim
The aim of this study is to assess the effects of triester glycerol oxide (TGO) on cutaneous wound epithelization process.
Material and methods
Fifty-four male Wistar rats were divided into 2 groups of 27 rats each: control(C) and TGO (PX). The groups have been divided into three subgroups which included nine rats each regarding the wound excision on the 3rd, 7th, and 10th days, respectively. The specimens were evaluated according to histological properties and hydroxyproline levels.
Results
Seventh day examination showed that PX and control groups present the same score. HP levels in the control group were significantly lower compared to PX groups.
Conclusion
TGO have positive effects on wound epithelization process by increased collagen synthesis.
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Funding source
This project was sponsored by Scientific Research Council of Gulhane Military Medical Academy.
Contributions of the authors
Metin Sencimen, Aydin Gülses, and Mustafa Ayna have designed the study and wrote the manuscript.
Serhat Sezgin, İsmail K. Gider, and Fevzi Erdemci have performed the surgical procedures.
Onder Angora has performed the pathological analysis.
Tuncer Cayci has performed the microbiological analysis.
The current study was conducted in the Department of Oral and Maxillary Surgery and Research Laboratories at Gülhane Military Medical Academy.
Additional information
An erratum to this article is available at http://dx.doi.org/10.1007/s10006-016-0602-1.
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Sezgin, S., Sencimen, M., Gülses, A. et al. An experimental study on the comparison of the effects of triester glycerol oxide on wound repair. Oral Maxillofac Surg 20, 273–279 (2016). https://doi.org/10.1007/s10006-016-0566-1
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DOI: https://doi.org/10.1007/s10006-016-0566-1