Skip to main content
Erschienen in: Clinical Rheumatology 2/2007

01.02.2007 | Original Article

A study of male patients with forearm fracture in Northern Ireland

verfasst von: Stephen Wright, Timothy Beringer, Hugh Taggart, Don Keegan, Jim Kelly, Esme Whithead, Roly McKane, Colette McNally, Margaret McQuilken, Michael Finch

Erschienen in: Clinical Rheumatology | Ausgabe 2/2007

Einloggen, um Zugang zu erhalten

Abstract

Osteoporosis, although considered less common, still occurs in men. We present a cross-sectional study of a group of Northern Ireland men with low-trauma forearm fractures to determine the presence of osteoporosis and screen for secondary causes of low bone mineral density. Male patients aged 30–75 years, presenting with distal forearm fracture in 2000–2001 in Northern Ireland, were identified through a Colles fracture database. A total of 37 subjects consented to have bone mineral density measurements undertaken at the femoral neck, spine and forearm using a Lunar expert bone densitometer. Twenty-seven percent of the men had osteoporosis at the spine, femoral neck or forearm, as defined by a bone mineral density score of less than −2.5. We also found that 49% of patients had vitamin D insufficiency or deficiency, 27% had low serum testosterone, 14% had abnormal liver function test results, and 14% had raised parathyroid hormone. Only one patient received advice or treatment regarding osteoporosis at the time of fracture. Increased awareness of male osteoporosis and the need for screening for potential secondary causes in this group of patients is required, both at primary and secondary care level.
Literatur
1.
Zurück zum Zitat Melton LJ III (2001) The prevalence of osteoporosis: gender and racial comparison. Calcif Tissue Int 69:179–181PubMedCrossRef Melton LJ III (2001) The prevalence of osteoporosis: gender and racial comparison. Calcif Tissue Int 69:179–181PubMedCrossRef
2.
Zurück zum Zitat Farmer ME, White LR, Brody JA, Bailey KR (1984) Race and sex differences in hip fracture incidence. Am J Pub Health 74:1374–1378PubMed Farmer ME, White LR, Brody JA, Bailey KR (1984) Race and sex differences in hip fracture incidence. Am J Pub Health 74:1374–1378PubMed
3.
Zurück zum Zitat Melton LJ III, Chrischilles EA, Cooper C (1992) How may women have osteoporosis. J Bone Miner Res 7:1005–1009PubMed Melton LJ III, Chrischilles EA, Cooper C (1992) How may women have osteoporosis. J Bone Miner Res 7:1005–1009PubMed
4.
Zurück zum Zitat (1998) Osteoporosis: review of the evidence for prevention, diagnosis, treatment and cost effective analysis. Osteoporos Int 8(Suppl 4):53–56 (1998) Osteoporosis: review of the evidence for prevention, diagnosis, treatment and cost effective analysis. Osteoporos Int 8(Suppl 4):53–56
5.
Zurück zum Zitat Van Staa TP, Leufkens HGH, Cooper C (2002) Does a fracture at one site predict later fractures at other sites? Osteoporos Int 13:624–629PubMedCrossRef Van Staa TP, Leufkens HGH, Cooper C (2002) Does a fracture at one site predict later fractures at other sites? Osteoporos Int 13:624–629PubMedCrossRef
6.
Zurück zum Zitat Cuddihy MT, Gabriel SE, Crowsson CS, O’Fallon WM, Melton LJ III (1999) Forearm fractures as predictors of subsequent osteoporotic fractures. Osteoporos Int 9:469–475PubMed Cuddihy MT, Gabriel SE, Crowsson CS, O’Fallon WM, Melton LJ III (1999) Forearm fractures as predictors of subsequent osteoporotic fractures. Osteoporos Int 9:469–475PubMed
7.
Zurück zum Zitat Malmin H, Ljunghall S, Persson I, Naesen T, Kruseme UB, Bergstrom R (1993) Fracture of the distal forearm as a forecaster of subsequent hip fracture: a population-based cohort study with 24 years follow-up. Calcif Tissue Int 52:269–272CrossRef Malmin H, Ljunghall S, Persson I, Naesen T, Kruseme UB, Bergstrom R (1993) Fracture of the distal forearm as a forecaster of subsequent hip fracture: a population-based cohort study with 24 years follow-up. Calcif Tissue Int 52:269–272CrossRef
8.
Zurück zum Zitat Lauritzen JB, Schwartz P, McNair P, Lund B, Transbol I (1993) Radial and humeral fractures as predictors of subsequent hip, radial or humeral fractures in women, and their seasonal variation. Osteoporos Int 3:153–157CrossRef Lauritzen JB, Schwartz P, McNair P, Lund B, Transbol I (1993) Radial and humeral fractures as predictors of subsequent hip, radial or humeral fractures in women, and their seasonal variation. Osteoporos Int 3:153–157CrossRef
9.
Zurück zum Zitat Barlow DH, Chairman (1994) Report of the advisory group on osteoporosis. Department of Health, London, UK Barlow DH, Chairman (1994) Report of the advisory group on osteoporosis. Department of Health, London, UK
10.
Zurück zum Zitat Royal College of Physicians London (1999) Clinical guidelines for the prevention and treatment of osteoporosis. (report) Royal College of Physicians London (1999) Clinical guidelines for the prevention and treatment of osteoporosis. (report)
11.
Zurück zum Zitat Freedman KB, Kaplan FS, Bilker WB, Strom BL, Lowe RA (2000) Treatment of osteoporosis: Are physicians missing an opportunity? J Bone Joint Surg Am 82:1063–1070PubMed Freedman KB, Kaplan FS, Bilker WB, Strom BL, Lowe RA (2000) Treatment of osteoporosis: Are physicians missing an opportunity? J Bone Joint Surg Am 82:1063–1070PubMed
12.
Zurück zum Zitat Hajesar EE, Hawker G, Bogoch ER (2000) Investigation of treatment for osteoporosis in patients with fragility fractures. Can Med Assoc J 163:819–822 Hajesar EE, Hawker G, Bogoch ER (2000) Investigation of treatment for osteoporosis in patients with fragility fractures. Can Med Assoc J 163:819–822
13.
Zurück zum Zitat Torgerson DJ, Dolan P (1998) Prescribing by general practioners after an osteoporotic fracture. Ann Rheum Dis 57:378–379PubMedCrossRef Torgerson DJ, Dolan P (1998) Prescribing by general practioners after an osteoporotic fracture. Ann Rheum Dis 57:378–379PubMedCrossRef
14.
Zurück zum Zitat Diamond TH, Thornley SW, Sekel R, Smerdely P (1997) Hip fracture in elderly men: prognostic factors and outcomes. Med J Aust 167:412–415PubMed Diamond TH, Thornley SW, Sekel R, Smerdely P (1997) Hip fracture in elderly men: prognostic factors and outcomes. Med J Aust 167:412–415PubMed
15.
Zurück zum Zitat Kiebzak GM, Beinart GA, Perser K (2002) Undertreatment of osteoporosis in men with hip fracture. Arch Intern Med 162:2217–2220PubMedCrossRef Kiebzak GM, Beinart GA, Perser K (2002) Undertreatment of osteoporosis in men with hip fracture. Arch Intern Med 162:2217–2220PubMedCrossRef
16.
Zurück zum Zitat Center JR, Nguyen TV, Schneider D (1999) Mortality after all major types of osteoporotic fracture in men and women: an observational study. Lancet 353:878–882PubMedCrossRef Center JR, Nguyen TV, Schneider D (1999) Mortality after all major types of osteoporotic fracture in men and women: an observational study. Lancet 353:878–882PubMedCrossRef
17.
Zurück zum Zitat Feldstein A, Elmer PJ, Orwoll E, Herson M (2003) Bone mineral density measurement and treatment for osteoporosis in older individuals with fractures: a gap in evidence based practice guideline implementation. Arch Intern Med 163:2165–2170PubMedCrossRef Feldstein A, Elmer PJ, Orwoll E, Herson M (2003) Bone mineral density measurement and treatment for osteoporosis in older individuals with fractures: a gap in evidence based practice guideline implementation. Arch Intern Med 163:2165–2170PubMedCrossRef
18.
Zurück zum Zitat Kelepouris N, Harper KD, Gannon F, Kaplan FS, Haddad JG (1995) Severe osteoporosis in men. Ann Intern Med 123:452–460PubMed Kelepouris N, Harper KD, Gannon F, Kaplan FS, Haddad JG (1995) Severe osteoporosis in men. Ann Intern Med 123:452–460PubMed
19.
20.
Zurück zum Zitat Tuck SP, Raj N, Summers GD (2002) Is distal forearm fracture in men due to osteoporosis? Osteoporos Int 13:630–636PubMedCrossRef Tuck SP, Raj N, Summers GD (2002) Is distal forearm fracture in men due to osteoporosis? Osteoporos Int 13:630–636PubMedCrossRef
21.
Zurück zum Zitat Beringer TR, Finch M, Taggart HMcA, Whitehead E, Keegan DA, Kelly J, Lee G, McKane R, McNally C, McQuilken M (2005) A study of bone mineral density in women with forearm fracture in Northern Ireland. Osteoporos Int 16:430–434PubMedCrossRef Beringer TR, Finch M, Taggart HMcA, Whitehead E, Keegan DA, Kelly J, Lee G, McKane R, McNally C, McQuilken M (2005) A study of bone mineral density in women with forearm fracture in Northern Ireland. Osteoporos Int 16:430–434PubMedCrossRef
22.
Zurück zum Zitat Kanis JA, Melton LJ (1994) The diagnosis of osteoporosis. J Bone Miner Res 8:1137–1141CrossRef Kanis JA, Melton LJ (1994) The diagnosis of osteoporosis. J Bone Miner Res 8:1137–1141CrossRef
23.
Zurück zum Zitat Faulkner KG, Orwoll ES (2000) Use of the WHO criterion in me: is −2.5 the right number? Bone 15:S169 Faulkner KG, Orwoll ES (2000) Use of the WHO criterion in me: is −2.5 the right number? Bone 15:S169
24.
Zurück zum Zitat Orwoll ES, Scheele WH, Paul S (2003) The effect of teriparatide [human parathyroid hormone (1–34)] therapy on bone density in men with osteoporosis. J Bone Miner Res 18:9–15PubMedCrossRef Orwoll ES, Scheele WH, Paul S (2003) The effect of teriparatide [human parathyroid hormone (1–34)] therapy on bone density in men with osteoporosis. J Bone Miner Res 18:9–15PubMedCrossRef
25.
Zurück zum Zitat Finkelstein JS, Hayes A, Hunzelman JL, Wyland JJ (2003) The effects of parathyroid hormone, alendronate, or both in men with osteoporosis. N Engl J Med 349:1216–1221PubMedCrossRef Finkelstein JS, Hayes A, Hunzelman JL, Wyland JJ (2003) The effects of parathyroid hormone, alendronate, or both in men with osteoporosis. N Engl J Med 349:1216–1221PubMedCrossRef
26.
Zurück zum Zitat Ross PD, Davis JW, Epstein RS, Wasnich RD (1991) Pre-existing fractures and bone mass predict vertebral fracture incidence in women. Osteoporos Int 114:919–923 Ross PD, Davis JW, Epstein RS, Wasnich RD (1991) Pre-existing fractures and bone mass predict vertebral fracture incidence in women. Osteoporos Int 114:919–923
27.
Zurück zum Zitat Klotzbuecher CM, Ross PD, Landsman PB, Abbott TA, Berger M (2000) Patients with prior fractures have an increased risk of future fractures: a summary of the literature and statistical synthesis. J Bone Miner Res 15:721–739PubMedCrossRef Klotzbuecher CM, Ross PD, Landsman PB, Abbott TA, Berger M (2000) Patients with prior fractures have an increased risk of future fractures: a summary of the literature and statistical synthesis. J Bone Miner Res 15:721–739PubMedCrossRef
28.
Zurück zum Zitat McLellan AR, Gallacher SJ, Fraser M, McQuillian C (2003) The fracture liaison service: success of a program for the evaluation and management of patients with osteoporotic fracture. Osteoporos Int 14:1028–1034PubMedCrossRef McLellan AR, Gallacher SJ, Fraser M, McQuillian C (2003) The fracture liaison service: success of a program for the evaluation and management of patients with osteoporotic fracture. Osteoporos Int 14:1028–1034PubMedCrossRef
29.
Zurück zum Zitat Wright SA, McNally C, Beringer T, Marsh D, Finch MB (2005) Osteoporosis fracture liaison experience: the Belfast experience. Rheumatol Int 25:489–490PubMedCrossRef Wright SA, McNally C, Beringer T, Marsh D, Finch MB (2005) Osteoporosis fracture liaison experience: the Belfast experience. Rheumatol Int 25:489–490PubMedCrossRef
30.
Zurück zum Zitat Seeman E, Melton LJ, O'Fallon WM, Riggs BL (1993) Risk factors for spinal osteoporosis in men. Am J Med 75:977–983CrossRef Seeman E, Melton LJ, O'Fallon WM, Riggs BL (1993) Risk factors for spinal osteoporosis in men. Am J Med 75:977–983CrossRef
31.
Zurück zum Zitat Scane AC, Francis RM, Sutcliffe AM, Francis MJD, Rawlings DJ, Chapple CL (1999) Case-control study of the pathogenesis and sequelae of symptomatic vertebral fractures in men. Osteoporos Int 9:91–97PubMedCrossRef Scane AC, Francis RM, Sutcliffe AM, Francis MJD, Rawlings DJ, Chapple CL (1999) Case-control study of the pathogenesis and sequelae of symptomatic vertebral fractures in men. Osteoporos Int 9:91–97PubMedCrossRef
32.
Zurück zum Zitat Legrand E, Chappard D, Pascaretti C, Duquenne M, Krebs S, Rohmer V, Basle M-F, Audran M (2000) Trabecular bone architecture, bone mineral density, and vertebral fractures in male osteoporosis. J Bone Miner Res 15:13–19PubMedCrossRef Legrand E, Chappard D, Pascaretti C, Duquenne M, Krebs S, Rohmer V, Basle M-F, Audran M (2000) Trabecular bone architecture, bone mineral density, and vertebral fractures in male osteoporosis. J Bone Miner Res 15:13–19PubMedCrossRef
33.
34.
Zurück zum Zitat Katznelson L, Finkelstein JS, Schoenfeld DA (1996) Increase in bone density and lean body mass during testosterone administration in men with acquired hypogonadism. J Clin Endocrinol Metab 81:4358–4362PubMedCrossRef Katznelson L, Finkelstein JS, Schoenfeld DA (1996) Increase in bone density and lean body mass during testosterone administration in men with acquired hypogonadism. J Clin Endocrinol Metab 81:4358–4362PubMedCrossRef
35.
Zurück zum Zitat Behre HM, Kliesch S, Leifke F (1997) Long-term effect of testosterone therapy on bone mineral density in hypogonadal men. J Clin Endocrinol Metab 82:2386–2390PubMedCrossRef Behre HM, Kliesch S, Leifke F (1997) Long-term effect of testosterone therapy on bone mineral density in hypogonadal men. J Clin Endocrinol Metab 82:2386–2390PubMedCrossRef
36.
Zurück zum Zitat Snyder PJ, Peachey H, Hannoush P (1999) Effect of testosterone treatment on bone mineral density in men over 65 years of age. J Clin Endocrinol Metab 84:1966–1970PubMedCrossRef Snyder PJ, Peachey H, Hannoush P (1999) Effect of testosterone treatment on bone mineral density in men over 65 years of age. J Clin Endocrinol Metab 84:1966–1970PubMedCrossRef
37.
Zurück zum Zitat Slemenda CW, Christian JC, Reed T (1992) Long-term bone loss in men: effects of genetic and environmental factors. Ann Intern Med 117:286–291PubMed Slemenda CW, Christian JC, Reed T (1992) Long-term bone loss in men: effects of genetic and environmental factors. Ann Intern Med 117:286–291PubMed
38.
Zurück zum Zitat Spencer H, Rubio N, Rubio E (1986) Chronic alcoholism. Frequently overlooked cause of osteoporosis in men. Am J Med 80:393–397PubMedCrossRef Spencer H, Rubio N, Rubio E (1986) Chronic alcoholism. Frequently overlooked cause of osteoporosis in men. Am J Med 80:393–397PubMedCrossRef
39.
Zurück zum Zitat Johnston SD, Watson RG, McMillan SA, Sloan J, Love AH (1997) Prevalence of coeliac disease in Northern Ireland. Lancet 350:1370PubMedCrossRef Johnston SD, Watson RG, McMillan SA, Sloan J, Love AH (1997) Prevalence of coeliac disease in Northern Ireland. Lancet 350:1370PubMedCrossRef
40.
41.
Zurück zum Zitat Heaney RP, Dowell MS, Hale CA, Bendich A (2003) Calcium absorption varies within the reference range for serum 25-hydroxyvitamin D. J Am Coll Nutr 22:142–146PubMed Heaney RP, Dowell MS, Hale CA, Bendich A (2003) Calcium absorption varies within the reference range for serum 25-hydroxyvitamin D. J Am Coll Nutr 22:142–146PubMed
Metadaten
Titel
A study of male patients with forearm fracture in Northern Ireland
verfasst von
Stephen Wright
Timothy Beringer
Hugh Taggart
Don Keegan
Jim Kelly
Esme Whithead
Roly McKane
Colette McNally
Margaret McQuilken
Michael Finch
Publikationsdatum
01.02.2007
Verlag
Springer-Verlag
Erschienen in
Clinical Rheumatology / Ausgabe 2/2007
Print ISSN: 0770-3198
Elektronische ISSN: 1434-9949
DOI
https://doi.org/10.1007/s10067-006-0261-y

Weitere Artikel der Ausgabe 2/2007

Clinical Rheumatology 2/2007 Zur Ausgabe

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.