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Erschienen in: Clinical Rheumatology 2/2008

01.02.2008 | Case Report

Clostridium difficile: an under-recognized cause of reactive arthritis?

verfasst von: Julius Birnbaum, John G. Bartlett, Allan C. Gelber

Erschienen in: Clinical Rheumatology | Ausgabe 2/2008

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Abstract

Reactive arthritis usually presents as a sterile, inflammatory, asymmetric oligoarthritis, affecting large lower extremity joints. Extra-articular features (conjunctivitis, uveitis, enthesopathy, urethritis, balanitis, keratoderma blenorrhagicum) may occur. Common causes of enteric reactive arthritis are preceding infections attributable to Salmonella, Shigella, Campylobacter, and Yersinia. In contrast, Clostridium difficile is an uncommon cause of reactive arthritis, with only ∼40 reported cases. We describe a patient with an intense additive, asymmetric oligoarthritis after an antecedent C. difficile infection. The potential contribution of C. difficile to more insidious cases of undifferentiated oligoarthritis is discussed, with emphasis on corresponding therapeutic interventions.
Literatur
1.
Zurück zum Zitat Flores D, Marquez J, Garza M, Espinoza LR (2003) Reactive arthritis: newer developments. Rheum Dis Clin North Am 29(1):37–59, vi. FebPubMedCrossRef Flores D, Marquez J, Garza M, Espinoza LR (2003) Reactive arthritis: newer developments. Rheum Dis Clin North Am 29(1):37–59, vi. FebPubMedCrossRef
2.
Zurück zum Zitat Hill Gaston JS, Lillicrap MS (2003) Arthritis associated with enteric infection. Best Pract Res Clin Rheumatol 17(2):219–239. AprPubMedCrossRef Hill Gaston JS, Lillicrap MS (2003) Arthritis associated with enteric infection. Best Pract Res Clin Rheumatol 17(2):219–239. AprPubMedCrossRef
3.
Zurück zum Zitat McCluskey J, Riley TV, Owen ET, Langlands DR (1982) Reactive arthritis associated with Clostridium difficile. Aust N Z J Med 12(5):535–537. OctPubMed McCluskey J, Riley TV, Owen ET, Langlands DR (1982) Reactive arthritis associated with Clostridium difficile. Aust N Z J Med 12(5):535–537. OctPubMed
4.
Zurück zum Zitat Atkinson MH, McLeod BD (1988) Reactive arthritis associated with Clostridium difficile enteritis. J Rheumatol 15(3):520–522. MarPubMed Atkinson MH, McLeod BD (1988) Reactive arthritis associated with Clostridium difficile enteritis. J Rheumatol 15(3):520–522. MarPubMed
5.
Zurück zum Zitat Hayward RS, Wensel RH, Kibsey P (1990) Relapsing Clostridium difficile colitis and Reiter's syndrome. Am J Gastroenterol 85(6):752–756. JunPubMed Hayward RS, Wensel RH, Kibsey P (1990) Relapsing Clostridium difficile colitis and Reiter's syndrome. Am J Gastroenterol 85(6):752–756. JunPubMed
6.
Zurück zum Zitat Loffler HA, Pron B, Mouy R, Wulffraat NM, Prieur AM (2004) Clostridium difficile-associated reactive arthritis in two children. Joint Bone Spine 71(1):60–62. JanPubMedCrossRef Loffler HA, Pron B, Mouy R, Wulffraat NM, Prieur AM (2004) Clostridium difficile-associated reactive arthritis in two children. Joint Bone Spine 71(1):60–62. JanPubMedCrossRef
7.
Zurück zum Zitat Jacobs A, Barnard K, Fishel R, Gradon JD (2001) Extracolonic manifestations of Clostridium difficile infections. Presentation of 2 cases and review of the literature. Medicine (Baltimore) 80(2):88–101. MarCrossRef Jacobs A, Barnard K, Fishel R, Gradon JD (2001) Extracolonic manifestations of Clostridium difficile infections. Presentation of 2 cases and review of the literature. Medicine (Baltimore) 80(2):88–101. MarCrossRef
8.
Zurück zum Zitat (1998) Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 19-1998. A 70-year-old man with diarrhea, polyarthritis, and a history of Reiter’s syndrome. N Engl J Med 338(25):1830–1836. Jun 18 (1998) Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 19-1998. A 70-year-old man with diarrhea, polyarthritis, and a history of Reiter’s syndrome. N Engl J Med 338(25):1830–1836. Jun 18
9.
Zurück zum Zitat Kocar IH, Caliskaner Z, Pay S, Turan M (1998) Clostridium difficile infection in patients with reactive arthritis of undetermined etiology. Scand J Rheumatol 27(5):357–362PubMedCrossRef Kocar IH, Caliskaner Z, Pay S, Turan M (1998) Clostridium difficile infection in patients with reactive arthritis of undetermined etiology. Scand J Rheumatol 27(5):357–362PubMedCrossRef
10.
Zurück zum Zitat Putterman C, Rubinow A (1993) Reactive arthritis associated with Clostridium difficile pseudomembranous colitis. Semin Arthritis Rheum 22(6):420–426. JunPubMedCrossRef Putterman C, Rubinow A (1993) Reactive arthritis associated with Clostridium difficile pseudomembranous colitis. Semin Arthritis Rheum 22(6):420–426. JunPubMedCrossRef
11.
Zurück zum Zitat Goldman WM, Avicolli AS, Lutwick S (1994) Clostridium difficile colitis. N Engl J Med 330(24):1755. Jun 16PubMed Goldman WM, Avicolli AS, Lutwick S (1994) Clostridium difficile colitis. N Engl J Med 330(24):1755. Jun 16PubMed
12.
Zurück zum Zitat Duchmann R, May E, Ackermann B, Goergen B, Meyer zum Buschenfelde KH, Marker-Hermann E (1996) HLA-B27-restricted cytotoxic T lymphocyte responses to arthritogenic enterobacteria or self-antigens are dominated by closely related TCRBV gene segments. A study in patients with reactive arthritis. Scand J Immunol 43(1):101–108. JanPubMedCrossRef Duchmann R, May E, Ackermann B, Goergen B, Meyer zum Buschenfelde KH, Marker-Hermann E (1996) HLA-B27-restricted cytotoxic T lymphocyte responses to arthritogenic enterobacteria or self-antigens are dominated by closely related TCRBV gene segments. A study in patients with reactive arthritis. Scand J Immunol 43(1):101–108. JanPubMedCrossRef
Metadaten
Titel
Clostridium difficile: an under-recognized cause of reactive arthritis?
verfasst von
Julius Birnbaum
John G. Bartlett
Allan C. Gelber
Publikationsdatum
01.02.2008
Verlag
Springer-Verlag
Erschienen in
Clinical Rheumatology / Ausgabe 2/2008
Print ISSN: 0770-3198
Elektronische ISSN: 1434-9949
DOI
https://doi.org/10.1007/s10067-007-0710-2

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