Skip to main content
Erschienen in: Clinical Rheumatology 1/2010

01.01.2010 | Case Report

Hypertrophic pachymeningitis with MPO-ANCA-positive vasculitis

verfasst von: Taro Horino, Toshihiro Takao, Yoshinori Taniguchi, Yoshio Terada

Erschienen in: Clinical Rheumatology | Ausgabe 1/2010

Einloggen, um Zugang zu erhalten

Abstract

A 75-year-old man presented with headache, right facial palsy, and left hemiparesis. Because of elevated myeloperoxidase-antineutrophil cytoplasmic antibody (MPO-ANCA) titers and findings from magnetic resonance imaging (MRI) which were compatible with hypertrophic pachymeningitis (HP), he was diagnosed with MPO-ANCA-positive HP. He was treated with the combination therapy of steroid and cyclophosphamide (CY), leading to good prognosis. We present a case of HP associated with MPO-ANCA-positive vasculitis and emphasize the importance of MPO-ANCA tests as a predictable factor for relapse of the disease in order to start earlier treatment for the disease.
Literatur
1.
Zurück zum Zitat Nakamura T, Hirakawa K, Higashi S et al (2007) CD8+ T lymphocytes infiltrate predominantly in the inflammatory foci of MPO-ANCA-positive thoracic hypertrophic pachymeningitis in a patient with HLA-A24. Mod Rheumatol 17:75–80CrossRefPubMed Nakamura T, Hirakawa K, Higashi S et al (2007) CD8+ T lymphocytes infiltrate predominantly in the inflammatory foci of MPO-ANCA-positive thoracic hypertrophic pachymeningitis in a patient with HLA-A24. Mod Rheumatol 17:75–80CrossRefPubMed
2.
Zurück zum Zitat Kupersmith MJ, Martin V, Heller G et al (2004) Idiopathic hypertrophic pachymeningitis. Neurology 62:686–694PubMed Kupersmith MJ, Martin V, Heller G et al (2004) Idiopathic hypertrophic pachymeningitis. Neurology 62:686–694PubMed
3.
Zurück zum Zitat Nagashima T, Maguchi S, Terayama Y et al (2000) P-ANCA-positive Wegener's granulomatosis presenting with hypertrophic pachymeningitis and multiple cranial neuropathies: case report and review of literature. Neuropathology 1:23–30CrossRef Nagashima T, Maguchi S, Terayama Y et al (2000) P-ANCA-positive Wegener's granulomatosis presenting with hypertrophic pachymeningitis and multiple cranial neuropathies: case report and review of literature. Neuropathology 1:23–30CrossRef
4.
Zurück zum Zitat Martin N, Masson C, Henin D et al (1989) Hypertrophic cranial pachymeningitis. Assessment with CT and MR imaging. Am J Neuroradiol 10:477–484PubMed Martin N, Masson C, Henin D et al (1989) Hypertrophic cranial pachymeningitis. Assessment with CT and MR imaging. Am J Neuroradiol 10:477–484PubMed
5.
Zurück zum Zitat Kallenberg CG, Brouwer E, Weening JJ et al (1994) Anti-neutrophil cytoplasmic antibodies: current diagnostic and pathophysiological potential. Kidney Int 46:1–15CrossRefPubMed Kallenberg CG, Brouwer E, Weening JJ et al (1994) Anti-neutrophil cytoplasmic antibodies: current diagnostic and pathophysiological potential. Kidney Int 46:1–15CrossRefPubMed
6.
Zurück zum Zitat Newman NJ, Slamovits TL, Friedland S et al (1995) Neuro-ophthalmic manifestations of meningocerebral inflammation from the limited form of Wegener's granulomatosis. Am J Ophthalmol 120:613–621PubMed Newman NJ, Slamovits TL, Friedland S et al (1995) Neuro-ophthalmic manifestations of meningocerebral inflammation from the limited form of Wegener's granulomatosis. Am J Ophthalmol 120:613–621PubMed
7.
Zurück zum Zitat Hoffman GS, Kerr GS, Leavitt RY et al (1992) Wegener granulomatosis: an analysis of 158 patients. Ann Intern Med 116:488–498PubMed Hoffman GS, Kerr GS, Leavitt RY et al (1992) Wegener granulomatosis: an analysis of 158 patients. Ann Intern Med 116:488–498PubMed
8.
Zurück zum Zitat Hayashi Y, Sugawara H, Otsuka M et al (2008) Fatal hemoperitoneum preceded by cranial hypertrophic pachymeningitis in a patient with ANCA-positive microscopic polyangitis. Intern Med 47:1061–1063CrossRefPubMed Hayashi Y, Sugawara H, Otsuka M et al (2008) Fatal hemoperitoneum preceded by cranial hypertrophic pachymeningitis in a patient with ANCA-positive microscopic polyangitis. Intern Med 47:1061–1063CrossRefPubMed
Metadaten
Titel
Hypertrophic pachymeningitis with MPO-ANCA-positive vasculitis
verfasst von
Taro Horino
Toshihiro Takao
Yoshinori Taniguchi
Yoshio Terada
Publikationsdatum
01.01.2010
Verlag
Springer-Verlag
Erschienen in
Clinical Rheumatology / Ausgabe 1/2010
Print ISSN: 0770-3198
Elektronische ISSN: 1434-9949
DOI
https://doi.org/10.1007/s10067-009-1269-x

Weitere Artikel der Ausgabe 1/2010

Clinical Rheumatology 1/2010 Zur Ausgabe

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.