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Erschienen in: Neurological Sciences 4/2011

01.08.2011 | Case Report

Microscopic polyangiitis presenting with peripheral and central neurological manifestations

verfasst von: S. Ben Sassi, I. Ben Ghorbel, H. Mizouni, M. H. Houman, F. Hentati

Erschienen in: Neurological Sciences | Ausgabe 4/2011

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Abstract

Although peripheral neuropathy is a common complication of microscopic angiitis, manifestations involving the muscle and the central nervous system have been rarely reported. We describe a 48-year-old man who rapidly developed a clinical picture of mononeuritis multiplex. A month after the appearance of the primary symptoms, he became comatose and had left hemiplegia in relation with a massive cerebral haematoma. Laboratory data revealed signs of inflammation, glomerular dysfunction with microhaematuria, and positive myeloperoxidase-antineutrophil cytoplasmic antibodies. The neuromuscular biopsy disclosed a small-vessel vasculitis, consisting with microscopic angiitis, associated with myositis and extensive axonal loss. The patient had surgical evacuation of the haematoma and received immunosuppressive therapy with good outcome. Thus, microscopic angiitis should be considered as a differential diagnosis in cases of myositis and intracerebral haemorrhage.
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Metadaten
Titel
Microscopic polyangiitis presenting with peripheral and central neurological manifestations
verfasst von
S. Ben Sassi
I. Ben Ghorbel
H. Mizouni
M. H. Houman
F. Hentati
Publikationsdatum
01.08.2011
Verlag
Springer Milan
Erschienen in
Neurological Sciences / Ausgabe 4/2011
Print ISSN: 1590-1874
Elektronische ISSN: 1590-3478
DOI
https://doi.org/10.1007/s10072-011-0653-x

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