Abstract
Aim
In this study, the aim was to identify the incidence of sarcopenia and dynapenia according to disease stage among idiopathic Parkinson’s disease (IPD) patients and collect data to illuminate precautions related to reducing the disease load.
Method
The study was completed with 166 patients divided by stage according to modified Hoehn and Yahr (HYR) criteria and 249 healthy volunteers aged from 18 to 39 and 68 to 75 years met the inclusion criteria. In our prospective and cross-sectional study, patients with IPD according to “UK Brain Bank” diagnostic criteria had the Unified Parkinson’s Disease Rating Scale (UPDRS) and HYR scales applied. The patient and control groups had skeletal muscle mass index (SMMI), muscle power, and physical performance assessed. Diagnosis of sarcopenia used the European Working Group on Sarcopenia in Older People (EWGSOP) diagnostic criteria.
Results
In our study, in parallel with the increase in disease stage among IPD patients, the incidence of sarcopenia (led by severe sarcopenia) and dynapenia was high compared to that among the control group of the same age.
Conclusion
In the early stages of chronic progressive diseases like IPD, identification of sarcopenia and dynapenia is important considering the limitations of disease-preventive effects in treatments applied after diagnosis.
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To complete this study with the aim of determining the incidence of sarcopenia and dynapenia among IPD patients monitored by Ordu University Education and Research Hospital and Ordu State University, permission was granted by the General Secretariate of Ordu Provincial Union of Public Hospitals and the ethics committee of Ordu University Education and Research Hospital, decision number 2017/108.
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Yazar, T., Yazar, H.O., Zayimoğlu, E. et al. Incidence of sarcopenia and dynapenia according to stage in patients with idiopathic Parkinson’s disease. Neurol Sci 39, 1415–1421 (2018). https://doi.org/10.1007/s10072-018-3439-6
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DOI: https://doi.org/10.1007/s10072-018-3439-6