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Lasers in Medical Science
Erschienen in: Lasers in Medical Science 1/2012

01.01.2012 | Original Article

Effects of 940 nm light-emitting diode (led) on sciatic nerve regeneration in rats

verfasst von: Karla Guivernau Gaudens Serafim, Solange de Paula Ramos, Franciele Mendes de Lima, Marcelo Carandina, Osny Ferrari, Ivan Frederico Lupiano Dias, Dari de Oliveira Toginho Filho, Cláudia Patrícia Cardoso Martins Siqueira

Erschienen in: Lasers in Medical Science | Ausgabe 1/2012

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Abstract

The objective of the present study was to evaluate the effect of 940 nm wavelength light emitting diode (LED) phototherapy on nerve regeneration in rats. Forty male Wistar rats weighing approximately 300 g each were divided into four groups: control (C); control submitted to LED phototherapy (CLed); Sciatic Nerve Lesion without LED phototherapy (L); Sciatic Nerve Lesion with LED phototherapy (LLed). The lesion was caused by crushing the right sciatic nerve. A dose of 4 J/cm2 was used for ten consecutive days beginning on the first postoperative day. Groups C and L were submitted to the same procedure as the LLed group, but the equipment was turned off. The LED phototherapy with 940 nm wavelength reduced the areas of edema, the number of mononuclear cells present in the inflammatory infiltration, and increased functional recovery scores at 7, 14 and 21 days. The results suggest that the use of phototherapy at 940 nm after nerve damage improves morphofunctional recovery and nerve regeneration.
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Metadaten
Titel
Effects of 940 nm light-emitting diode (led) on sciatic nerve regeneration in rats
verfasst von
Karla Guivernau Gaudens Serafim
Solange de Paula Ramos
Franciele Mendes de Lima
Marcelo Carandina
Osny Ferrari
Ivan Frederico Lupiano Dias
Dari de Oliveira Toginho Filho
Cláudia Patrícia Cardoso Martins Siqueira
Publikationsdatum
01.01.2012
Verlag
Springer-Verlag
Erschienen in
Lasers in Medical Science / Ausgabe 1/2012
Print ISSN: 0268-8921
Elektronische ISSN: 1435-604X
DOI
https://doi.org/10.1007/s10103-011-0923-0

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