nach oben

Erschienen in:

01.05.2013 | Original Article

Prevention and treatment of mice paw edema by near-infrared low-level laser therapy on lymph nodes

verfasst von: Daiane Thais Meneguzzo, Luciana Almeida Lopes, Rodney Pallota, Leila Soares-Ferreira, Rodrigo Álvaro Brandão Lopes-Martins, Martha Simões Ribeiro

Erschienen in: Lasers in Medical Science | Ausgabe 3/2013

Einloggen, um Zugang zu erhalten

Abstract

Low-level laser therapy (LLLT) has been demonstrated to modulate inflammatory processes and immunological responses. The aim of this work was to investigate the hypothesis that near infrared LLLT (830 nm) over lymph nodes may reduce paw edema and contribute to the modulation of inflammation. The edema was induced by carrageenan inoculation (CGN) into the plantar surface of 100 male mice left hind paw. Animals were divided into five groups: CGN (control), no treatment; Diclo, sodium diclofenac; Paw, LLLT on the paw; Ly, LLLT on the inguinal lymph nodes; and Paw+Ly, LLLT in both paw and lymph nodes, and subdivided according to moment of irradiation: A—1 h and 2 h before CGN, B—1 h and immediately before CGN, C—1 and 2 h after CGN, and D—3.5 and 4.5 h after CGN. The parameters used were: energy = 1 J, fluence = 35 J/cm², power = 100 mW during 10 s. Paw volume was measured before and 1 to 6 h after CGN, and myeloperoxidase (MPO) activity was analyzed. Edema prevention was obtained by the irradiation of Paw+Ly at moment A and at Ly at moment B, inhibition of edema formation was achieved by either Paw or Ly at moment C, and edema treatment was obtained by Paw or Ly at moment D (p < 0.05). MPO activity was significantly reduced on Paw at moment A, Paw and Ly on C, and in all irradiated groups on B and D. Our results suggest that LLLT was able to produce both anti-inflammatory and pro-inflammatory effects depending on to the site and moment of irradiation.

Dan AE, Thygesen TH, Pinholt EM (2010) Corticosteroid administration in oral and orthognathic surgery: a systematic review of the literature and meta-analysis. J Oral Maxillofac Surg 68:2207–2220PubMedCrossRef

Gold DA, Adelwahab ID, Hermann G (1989) Osteonecrosis of both medial tibial condyles following short-term steroid therapy: a case report. Bull Hosp Jt Dis Orthop Inst 49:103–106PubMed

Little JW, Falace DA (1988) Adrenal insufficiency in dental management of the medically compromised patient. Mosby, St Louis

Durmus M, Karaaslan E, Ozturk E et al (2003) The effects of single dose dexamethasone on wound healing in rats. Anesth Analg 97:1377–1380PubMedCrossRef

Chedid M, Hoyle JR, Csaky KG et al (1996) Glucocorticoids inhibit keratinocyte growth factor production in primary dermal fibroblasts. Endocrinology 137:2232–2237PubMedCrossRef

Galen DM, Beck M, Buchbinder D (1997) Steroid psychosis after orthognathic surgery: a case report. J Oral Maxillofac Surg 55:294–297PubMedCrossRef

Morais NC, Barbosa AM, Vale ML, Villaverde AB, de Lima CJ, Cogo JC, Zamuner SR (2010) Anti-inflammatory effect of low-level laser and light-emitting diode in zymosan-induced arthritis. Photomed Laser Surg 28:227–232PubMedCrossRef

Bjordal JM, Bensadoun RJ, Tunèr J, Frigo L, Gjerde K, Lopes-Martins RA (2011) A systematic review with meta-analysis of the effect of low-level laser therapy (LLLT) in cancer therapy-induced oral mucositis. Support Care Cancer 19:1069–1077PubMedCrossRef

Pallotta RC, Bjordal JM, Frigo L, Leal Junior EC, Teixeira S, Marcos RL, Ramos L, de Moura Messias F, Lopes-Martins RA (2011) Infrared (810-nm) low-level laser therapy on rat experimental knee inflammation. Lasers Med Sci Apr 12. [Epub ahead of print]

10.

Correa F, Lopes Martins RA, Correa JC, Iversen VV, Joenson J, Bjordal JM (2007) Low-level laser therapy (GaAs lambda = 904 nm) reduces inflammatory cell migration in mice with lipopolysaccharide-induced peritonitis. Photomed Laser Surg 25:245–249PubMedCrossRef

11.

Albertini R, Aimbire FSC, Correa FI, Ribeiro W, Cogo JC, Antunes E, Teixeira SA, De Nucci G, Castro-Faria-Neto HC, Zângaro RA, Lopes-Martins RAB (2004) Effects of different protocol doses of low power gallium–aluminum–arsenate (Ga–Al–As) laser radiation (650 nm) on carrageenan induced rat paw oedema. J Photochem Photobiol B 74:101–107PubMedCrossRef

12.

Albertini R, Aimbire F, Villaverde AB, Silva JA Jr, Costa MS (2007) COX-2 mRNA expression decreases in the subplantar muscle of rat paw subjected to carrageenan-induced inflammation after low level laser therapy. Inflamm Res 56:228–229PubMedCrossRef

13.

Lopes-Martins RAB, Albertini R, Martins PSLL, Bjordal JM, Faria NetO HCC (2005) Spontaneous effects of low-level laser therapy (650 nm) in acute inflammatory mouse pleurisy induced by carrageenan. Photomed Laser Surg 23:377–381PubMedCrossRef

14.

Aimbire F, Albertine R, Magalhães RG, Lopes-Martins RAB, Castro-Faria-Neto RA, Zângaro RA, Chavantes MC, Pacheco MTT (2005) Effect of LLLT Ga–Al–As (685 nm) on LPS-induced inflammation of the airway and lung in the rat. Lasers Med Sci 20:11–20PubMedCrossRef

15.

Carati CJ, Anderson SN, Gannon BJ, Piller NB (2003) Treatment of postmastectomy lymphedema with low-level laser therapy: a double blind, placebo-controlled trial. Cancer 98:1114–1122PubMedCrossRef

16.

Kaviani A, Fateh M, Nooraie RY, Alinagi-zadeh M, Ataie-Fashtami L (2006) Low-level laser therapy in management of postmastectomy lymphedema. Lasers Med Sci 21:90–94PubMedCrossRef

17.

Lau RWL, Cheing GLY (2009) Managing postmastectomy lymphedema with low-level laser therapy. Photomed Laser Surg 27:763–769PubMedCrossRef

18.

Medrado AR, Pugliese LS, Reis SR, Andrade ZA (2003) Influence of low level laser therapy on wound healing and its biological action upon myofibroblasts. Lasers Surg Med 32:239–244PubMedCrossRef

19.

Woodruff LD, Bounkeo JM, Brannon WM, Dawes KS, Barham CD, Waddell DL, Enwemeka CS (2004) The efficacy of laser therapy in wound repair: a meta-analysis of the literature. Photomed Laser Surg 22:241–247PubMedCrossRef

20.

Viegas VN, Abreu ME, Viezzer C, Machado DC, Filho MS, Silva DN, Pagnoncelli RM (2007) Effect of low-level laser therapy on inflammatory reactions during wound healing: comparison with meloxicam. Photomed Laser Surg 25:467–473PubMedCrossRef

21.

Tadakuma T (1993) Possible application of the laser in immunobiology. Keio J Med 42:180–182PubMedCrossRef

22.

Henriques MG, Silva PM, Martins MA, Flores CA, Cunha FQ, Assreuy-Filho J, Cordeiro RS (1987) Mouse paw edema. A new model for inflammation? Braz J Med Biol Res 20:243–249PubMed

23.

Harrell MI, Iritani BM, Ruddell A (2008) Technical note Lymph node mapping in the mouse. J Immunol Methods 332:170–174PubMedCrossRef

24.

Bortone F, Santos HA, Albertini R, Pesquero JB, Costa MS, Silva JA Jr (2008) Low level laser therapy modulates kinin receptors mRNA expression in the subplantar muscle of rat paw subjected to carrageenan-induced inflammation. Int Immunopharmacol 8:206–210PubMedCrossRef

25.

Albertini R, Villaverde AB, Aimbire F, Bjordal JM, Brugnera JRA, Mittmann J, Silva JRJA, Costa MS (2008) Cytokine mRNA expression is decreased in the subplantar muscle of rat paw subjected to carrageenan-induced inflammation after low-level laser therapy. Photomed Laser Surg 26:19–24PubMedCrossRef

26.

Bjordal JM, Johnson MI, Iversen V, Aimbire F, Lopes-Martins RA (2006) Photoradiation in acute pain: a systematic review of possible mechanisms of action and clinical effects in randomized placebo-controlled trials. Photomed Laser Surg 24:158–168PubMedCrossRef

27.

Honmura A, Yanase M, Obata J, Haruki E (1992) Therapeutic effect of Ga-Al-As diode laser irradiation on experimentally induced inflammation in rats. Lasers Surg Med 12:441–449PubMedCrossRef

28.

Tong M, Liu YF, Zhao XN, Yan CZ, Hu ZR, Zhang ZX (2000) Effects of different wavelengths of low level laser irradiation on murine immunological activity and intracellular Ca²⁺ in human lymphocytes and cultured cortical neurogliocytes. Lasers Med Sci 15:201–206CrossRef

29.

Boschi ES, Leite CE, Saciura VC, Caberlon E, Lunardelli A, Bitencourt S, Melo DA, Oliveira JR (2008) Anti-Inflammatory effects of low-level laser therapy (660 nm) in the early phase in carrageenan-induced pleurisy in rat. Lasers Surg Med 40:500–508PubMedCrossRef

30.

Karu T (1989) Photobiology of low-power lasers effects. Health Phys 56:691–704PubMedCrossRef

31.

Pereira AN, Eduardo CP, Matson E, Marques MM (2002) Effect of low-power laser irradiation on cell growth and procollagen synthesis of cultured fibroblasts. Lasers Surg Med 31:263–267PubMedCrossRef

32.

Meneguzzo DT, Eduardo CP, Ribeiro MS, Marques MM (2008) Influence of the fractioned irradiation energy in the phototherapy with low intensity laser on the growth of human dental pulp fibroblasts. Progress Biom Optics Imag 9:A1–A9

33.

Bensadoun RJ, Franquin JC, Ciais G et al (1999) Low-energy He/Ne laser in the prevention of radiation-induced mucositis—a multicenter phase III randomized study in patients with head and neck cancer. Support Care Cancer 7:244–252PubMedCrossRef

34.

Yu W, Naim JO, Lanzafame RJ (1997) Effects of photostimulation on wound healing in diabetic mice. Lasers Surg Med 20:56–63PubMedCrossRef

35.

Rochkind S, Rousso M, Nissan M, Villarreal M, Barr-Nea L, Rees DG (1989) Systemic effects of low-power laser irradiation on the peripheral and central nervous system, cutaneous wounds and burns. Lasers Surg Med 9:174–182PubMedCrossRef

36.

Kandolf-Sekulovic L, Kataranovski M, Pavlovic MD (2003) Immunomodulatory effects of low-intensity near-infrared laser irradiation on contact hypersensitivity reaction. Photodermatol Photoimmunol Photomed 19:203–212PubMedCrossRef

37.

Sliney DH (2007) Radiometric quantities and units used in photobiology and photochemistry: recommendations of the Commission Internationale de L’Eclairage (International Commission on Illumination). Photochem Photobiol 83:425–432PubMedCrossRef

38.

Maegawa Y, Itoh T, Hosokawa T, Yaegashi K, Nishi M (2000) Effects of near-infrared low-level laser irradiation on microcirculation. Laser Surg Med 27:427–437CrossRef

39.

Vladimirov YA, Osipov AN, Klebanov GI (2004) Photobiological principles of therapeutic applications of laser radiation. Biochemistry 69:81–90PubMed

Titel: Prevention and treatment of mice paw edema by near-infrared low-level laser therapy on lymph nodes
verfasst von: Daiane Thais Meneguzzo
Luciana Almeida Lopes
Rodney Pallota
Leila Soares-Ferreira
Rodrigo Álvaro Brandão Lopes-Martins
Martha Simões Ribeiro
Publikationsdatum: 01.05.2013
Verlag: Springer-Verlag
Erschienen in: Lasers in Medical Science / Ausgabe 3/2013
Print ISSN: 0268-8921
Elektronische ISSN: 1435-604X
DOI: https://doi.org/10.1007/s10103-012-1163-7

Springer Medizin

Abstract

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 3/2013

Clinical and histologic effects from CO2 laser treatment of keloids

Numerical simulation of endovenous laser treatment of the incompetent great saphenous vein with external air cooling

Lasers for the treatment of intraocular tumors

Efficacy of minimally invasive nonthermal laser-induced optical breakdown technology for skin rejuvenation

Low level diode laser accelerates wound healing

The efficacy of the use of IR laser phototherapy associated to biphasic ceramic graft and guided bone regeneration on surgical fractures treated with wire osteosynthesis: a comparative laser fluorescence and Raman spectral study on rabbits