nach oben

Erschienen in:

29.11.2017 | Original Article

When is the best moment to apply photobiomodulation therapy (PBMT) when associated to a treadmill endurance-training program? A randomized, triple-blinded, placebo-controlled clinical trial

verfasst von: Eduardo Foschini Miranda, Shaiane Silva Tomazoni, Paulo Roberto Vicente de Paiva, Henrique Dantas Pinto, Denis Smith, Larissa Aline Santos, Paulo de Tarso Camillo de Carvalho, Ernesto Cesar Pinto Leal-Junior

Erschienen in: Lasers in Medical Science | Ausgabe 4/2018

Einloggen, um Zugang zu erhalten

Abstract

Photobiomodulation therapy (PBMT) employing low-level laser therapy (LLLT) and/or light emitting diode therapy (LEDT) has emerged as an electrophysical intervention that could be associated with aerobic training to enhance beneficial effects of aerobic exercise. However, the best moment to perform irradiation with PBMT in aerobic training has not been elucidated. The aim of this study was to assess the effects of PBMT applied before and/or after each training session and to evaluate outcomes of the endurance-training program associated with PBMT. Seventy-seven healthy volunteers completed the treadmill-training protocol performed for 12 weeks, with 3 sessions per week. PBMT was performed before and/or after each training session (17 sites on each lower limb, using a cluster of 12 diodes: 4 × 905 nm super-pulsed laser diodes, 4 × 875 nm infrared LEDs, and 4 × 640 nm red LEDs, dose of 30 J per site). Volunteers were randomized in four groups according to the treatment they would receive before and after each training session: PBMT before + PBMT after, PBMT before + placebo after, placebo before + PBMT after, and placebo before + placebo after. Assessments were performed before the start of the protocol and after 4, 8, and 12 weeks of training. Primary outcome was time until exhaustion; secondary outcome measures were oxygen uptake and body fat. PBMT applied before and after aerobic exercise training sessions (PBMT before + PBMT after group) significantly increased (p < 0.05) the percentage of change of time until exhaustion and oxygen uptake compared to the group treated with placebo before and after aerobic exercise training sessions (placebo before + placebo after group) at 4th, 8th, and 12th week. PBMT applied before and after aerobic exercise training sessions (PBMT before + PBMT after group) also significantly improved (p < 0.05) the percentage of change of body fat compared to the group treated with placebo before and after aerobic exercise training sessions (placebo before + placebo after group) at 8th and 12th week. PBMT applied before and after sessions of aerobic training during 12 weeks can increase the time-to-exhaustion and oxygen uptake and also decrease the body fat in healthy volunteers when compared to placebo irradiation before and after exercise sessions. Our outcomes show that PBMT applied before and after endurance-training exercise sessions lead to improvement of endurance three times faster than exercise only.

Warburton DE, Nicol CW, Bredin SS (2006) Health benefits of physical activity: the evidence. CMAJ 174:801–809CrossRefPubMedPubMedCentral

Warburton DE, Katzmarzyk PT, Rhodes RE, Shephard RJ (2007) Evidence-informed physical activity guidelines for Canadian adults. Can J Public Health 98:S16–S68PubMed

Goodman JM, Thomas SG, Burr J (2011) Evidence-based risk assessment and recommendations for exercise testing and physical activity clearance in apparently healthy individuals. Appl Physiol Nutr Metab 36:S14–S32CrossRefPubMed

Chou CH, Hwang CL, Wu YT (2012) Effect of exercise on physical function, daily living activities, and quality of life in the frail older adults: a meta-analysis. Arch Phys Med Rehabil 93:237–244CrossRefPubMed

Jacobson BH, Smith D, Fronterhouse J, Kline C, Boolani A (2012) Assessment of the benefit of powered exercises for muscular endurance and functional capacity in elderly participants. J Phys Act Health 9:1030–1035CrossRefPubMed

de Vries NM, van Ravensberg CD, Hobbelen JS, Olde Rikkert MG, Staal JB, Nijhuis-van der Sanden MW (2012) Effects of physical exercise therapy on mobility, physical functioning, physical activity and quality of life in community-dwelling older adults with impaired mobility, physical disability and/or multi-morbidity: a meta-analysis. Ageing Res Rev 11:136–149CrossRefPubMed

MacKenzie-Shalders KL, Byrne NM, Slater GJ, King NA (2015) The effect of a whey protein supplement dose on satiety and food intake in resistance training athletes. Appetite 92:178–184CrossRefPubMed

Higgins S, Straight CR, Lewis RD (2016) The effects of preexercise caffeinated coffee ingestion on endurance performance: an evidence-based review. Int J Sport Nutr Exerc Metab 26:221–239CrossRefPubMed

Lanhers C, Pereira B, Naughton G, Trousselard M, Lesage FX, Dutheil F (2015) Creatine supplementation and lower limb strength performance: a systematic review and meta-analyses. Sports Med 45:1285–1294CrossRefPubMed

10.

De Brandt J, Spruit MA, Derave W, Hansen D, Vanfleteren LE, Burtin C (2016) Changes in structural and metabolic muscle characteristics following exercise-based interventions in patients with COPD: a systematic review. Expert Rev Respir Med 10:521–545CrossRefPubMed

11.

Leal Junior EC, Lopes-Martins RA, Vanin AA, Baroni BM, Grosselli D, De Marchi T, Iversen VV, Bjordal JM (2009) Effect of 830 nm low-level laser therapy in exercise-induced skeletal muscle fatigue in humans. Lasers Med Sci 24:425–431CrossRefPubMed

12.

Leal Junior EC, Lopes-Martins RA, Baroni BM, De Marchi T, Taufer D, Manfro DS, Rech M, Danna V, Grosselli D, Generosi RA, Marcos RL, Ramos L, Bjordal JM (2009) Effect of 830 nm low-level laser therapy applied before high-intensity exercises on skeletal muscle recovery in athletes. Lasers Med Sci 24:857–863CrossRefPubMed

13.

Antonialli FC, De Marchi T, Tomazoni SS, Vanin AA, dos Santos GV, de Paiva PR, Pinto HD, Miranda EF, de Tarso Camillo de Carvalho P, Leal-Junior EC (2014) Phototherapy in skeletal muscle performance and recovery after exercise: effect of combination of super-pulsed laser and light-emitting diodes. Lasers Med Sci 29:1967–1976CrossRefPubMed

14.

Miranda EF, de Oliveira LV, Antonialli FC, Vanin AA, de Carvalho PT, Leal-Junior EC (2015) Phototherapy with combination of super-pulsed laser and light-emitting diodes is beneficial in improvement of muscular performance (strength and muscular endurance), dyspnea, and fatigue sensation in patients with chronic obstructive pulmonary disease. Lasers Med Sci 30:437–443CrossRefPubMed

15.

Miranda EF, Vanin AA, Tomazoni SS, Grandinetti Vdos S, de Paiva PR, Machado Cdos S, Monteiro KK, Casalechi HL, de Tarso P, de Carvalho C, Leal-Junior EC (2016) Using pre-exercise photobiomodulation therapy combining super-pulsed lasers and light-emitting diodes to improve performance in progressive cardiopulmonary exercise tests. J Athl Train 51:129–135CrossRefPubMedPubMedCentral

16.

Da Silva Alves MA, Pinfildi CE, Neto LN, Lourenço RP, de Azevedo PH, Dourado VZ (2014) Acute effects of low-level laser therapy on physiologic and electromyographic responses to the cardiopulmonary exercise testing in healthy untrained adults. Lasers Med Sci 29:1945–1951CrossRefPubMed

17.

Vieira WH, Ferraresi C, Perez SE, Baldissera V, Parizotto NA (2012) Effects of low-level laser therapy (808 nm) on isokinetic muscle performance of young women submitted to endurance training: a randomized controlled clinical trial. Lasers Med Sci 27:497–504CrossRefPubMed

18.

De Marchi T, Leal Junior EC, Bortoli C, Tomazoni SS, Lopes-Martins RA, Salvador M (2012) Low-level laser therapy (LLLT) in human progressive-intensity running: effects on exercise performance, skeletal muscle status, and oxidative stress. Lasers Med Sci 27:231–236CrossRefPubMed

19.

Paolillo FR, Corazza AV, Paolillo AR, Borghi-Silva A, Arena R, Kurachi C, Bagnato VS (2014) Phototherapy during treadmill training improves quadriceps performance in postmenopausal women. Climacteric 17:285–293CrossRefPubMed

20.

Paolillo FR, Milan JC, Aniceto IV, Barreto SG, Rebelatto JR, Borghi-Silva A, Parizotto NA, Kurachi C, Bagnato VS (2011) Effects of infrared-LED illumination applied during high-intensity treadmill training in postmenopausal women. Photomed Laser Surg 29:639–645CrossRefPubMed

21.

Paolillo FR, Corazza AV, Borghi-Silva A, Parizotto NA, Kurachi C, Bagnato VS (2013) Infrared LED irradiation applied during high-intensity treadmill training improves maximal exercise tolerance in postmenopausal women: a 6-month longitudinal study. Lasers Med Sci 28:415–422CrossRefPubMed

22.

American College of Sports Medicine, Chodzko-Zajko WJ, Proctor DN, Fiatarone Singh MA, Minson CT, Nigg CR, Salem GJ, Skinner JS (2009) American College of Sports Medicine position stand. Exercise and physical activity for older adults. Med Sci Sports Exerc 41:1510–1530CrossRef

23.

Song M, Carroll DD, Fulton JE (2013) Meeting the 2008 physical activity guidelines for Americans among U.S. youth. Am J Prev Med 44:216–222CrossRefPubMed

24.

Grandinétti Vdos S, Miranda EF, Johnson DS, de Paiva PR, Tomazoni SS, Vanin AA, Albuquerque-Pontes GM, Frigo L, Marcos RL, de Carvalho PT, Leal-Junior EC (2015) The thermal impact of phototherapy with concurrent super-pulsed lasers and red and infrared LEDs on human skin. Lasers Med Sci 30:1575–1581CrossRefPubMed

25.

Powers SK, Howley ET (2015) Exercise physiology: theory and application to fitness and performance, 9th edn. McGraw-Hill, New York

26.

Marfell-Jones M, Olds T, Stewart A, Carter L (2006) International standards for anthropometric assessment. ISAK, Potchefstroom

27.

Borghi-Silva A, Arena R, Castello V, Simões RP, Martins LE, Catai AM, Costa D (2009) Aerobic exercise training improves autonomic nervous control in patients with COPD. Respir Med 103:1503–1510CrossRefPubMed

28.

Pinto HD, Vanin AA, Miranda EF, Tomazoni SS, Johnson DS, Albuquerque-Pontes GM, Aleixo IO Jr, Grandinetti VD, Casalechi HL, de Carvalho PT, Leal-Junior EC (2016) Photobiomodulation therapy improves performance and accelerates recovery of high-level rugby players in field test: a randomized, crossover, double-blind, placebo-controlled clinical study. J Strength Cond Res 30:3329–3338CrossRefPubMed

29.

de Paiva PR, Tomazoni SS, Johnson DS, Vanin AA, Albuquerque-Pontes GM, Machado CD, Casalechi HL, de Carvalho PT, Leal-Junior EC (2016) Photobiomodulation therapy (PBMT) and/or cryotherapy in skeletal muscle restitution, what is better? A randomized, double-blinded, placebo-controlled clinical trial. Lasers Med Sci 31:1925–1933CrossRefPubMed

30.

Duarte FO, Sene-Fiorese M, de Aquino Junior AE, da Silveira Campos RM, Masquio DC, Tock L, Garcia de Oliveira Duarte AC, Dâmaso AR, Bagnato VS, Parizotto NA (2015) Can low-level laser therapy (LLLT) associated with an aerobic plus resistance training change the cardiometabolic risk in obese women? A placebo-controlled clinical trial. J Photochem Photobiol B 153:103–110CrossRefPubMed

31.

Hayworth CR, Rojas JC, Padilla E, Holmes GM, Sheridan EC, Gonzalez-Lima F (2010) In vivo low-level light therapy increases cytochrome oxidase in skeletal muscle. Photochem Photobiol 86:673–680CrossRefPubMed

32.

Albuquerque-Pontes GM, Vieira RP, Tomazoni SS, Caires CO, Nemeth V, Vanin AA, Santos LA, Pinto HD, Marcos RL, Bjordal JM, de Carvalho PT, Leal-Junior EC (2015) Effect of pre-irradiation with different doses, wavelengths, and application intervals of low-level laser therapy on cytochrome c oxidase activity in intact skeletal muscle of rats. Lasers Med Sci 30:59–66CrossRefPubMed

33.

De Marchi T, Schmitt VM, Danúbia da Silva Fabro C, da Silva LL, Sene J, Tairova O, Salvador M (2017) Phototherapy for improvement of performance and exercise recovery: comparison of 3 commercially available devices. J Athl Train 52:429–438CrossRefPubMed

34.

Leal-Junior EC, Johnson DS, Saltmarche A, Demchak T (2014) Adjunctive use of combination of super-pulsed laser and light-emitting diodes phototherapy on nonspecific knee pain: double-blinded randomized placebo-controlled trial. Lasers Med Sci 29:1839–1847CrossRefPubMed

35.

Santos LA, Marcos RL, Tomazoni SS, Vanin AA, Antonialli FC, Grandinetti Vdos S, Albuquerque-Pontes GM, de Paiva PR, Lopes-Martins RÁ, de Carvalho PT, Bjordal JM, Leal-Junior EC (2014) Effects of pre-irradiation of low-level laser therapy with different doses and wavelengths in skeletal muscle performance, fatigue, and skeletal muscle damage induced by tetanic contractions in rats. Lasers Med Sci 29:1617–1626CrossRefPubMed

36.

Vanin AA, Miranda EF, Machado CS, de Paiva PR, Albuquerque-Pontes GM, Casalechi HL, de Tarso Camillo de Carvalho P, Leal-Junior EC (2016) What is the best moment to apply phototherapy when associated to a strength training program? A randomized, double-blinded, placebo-controlled trial: phototherapy in association to strength training. Lasers Med Sci 31:1555–1564CrossRefPubMed

37.

Aver Vanin A, De Marchi T, Tomazoni SS, Tairova O, Leão Casalechi H, de Tarso Camillo de Carvalho P, Bjordal JM, Leal-Junior EC (2016) Pre-exercise infrared low-level laser therapy (810 nm) in skeletal muscle performance and postexercise recovery in humans, what is the optimal dose? A randomized, double-blind, placebo-controlled clinical trial. Photomed Laser Surg 34:473–482CrossRefPubMed

38.

Machado AF, Micheletti JK, Vanderlei FM, Nakamura FY, Leal-Junior ECP, Netto Junior J, Pastre CM (2017) Effect of low-level laser therapy (LLLT) and light-emitting diodes (LEDT) applied during combined training on performance and post-exercise recovery: protocol for a randomized placebo-controlled trial. Braz J Phys Ther 21:296–304CrossRefPubMedPubMedCentral

39.

Leal-Junior EC, Vanin AA, Miranda EF, de Carvalho PT, Dal Corso S, Bjordal JM (2015) Effect of phototherapy (low-level laser therapy and light-emitting diode therapy) on exercise performance and markers of exercise recovery: a systematic review with meta-analysis. Lasers Med Sci 30:925–939CrossRefPubMed

40.

Leal-Junior EC (2015) Photobiomodulation therapy in skeletal muscle: from exercise performance to muscular dystrophies. Photomed Laser Surg 33:53–54CrossRefPubMedPubMedCentral

41.

Vanin AA, Verhagen E, Barboza SD, Costa LOP, Leal-Junior ECP (2017) Photobiomodulation therapy for the improvement of muscular performance and reduction of muscular fatigue associated with exercise in healthy people: a systematic review and meta-analysis. Lasers Med Sci. https://doi.org/10.1007/s10103-017-2368-6

42.

de Oliveira AR, Vanin AA, Tomazoni SS, Miranda EF, Albuquerque-Pontes GM, De Marchi T, Dos Santos Grandinetti V, de Paiva PRV, Imperatori TBG, de Carvalho PTC, Bjordal JM, Leal-Junior ECP (2017) Pre-exercise infrared photobiomodulation therapy (810 nm) in skeletal muscle performance and postexercise recovery in humans: what is the optimal power output? Photomed Laser Surg 35:595–603

Titel: When is the best moment to apply photobiomodulation therapy (PBMT) when associated to a treadmill endurance-training program? A randomized, triple-blinded, placebo-controlled clinical trial
verfasst von: Eduardo Foschini Miranda
Shaiane Silva Tomazoni
Paulo Roberto Vicente de Paiva
Henrique Dantas Pinto
Denis Smith
Larissa Aline Santos
Paulo de Tarso Camillo de Carvalho
Ernesto Cesar Pinto Leal-Junior
Publikationsdatum: 29.11.2017
Verlag: Springer London
Erschienen in: Lasers in Medical Science / Ausgabe 4/2018
Print ISSN: 0268-8921
Elektronische ISSN: 1435-604X
DOI: https://doi.org/10.1007/s10103-017-2396-2

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

When is the best moment to apply photobiomodulation therapy (PBMT) when associated to a treadmill endurance-training program? A randomized, triple-blinded, placebo-controlled clinical trial

Abstract

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Abstract

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 4/2018

One-pot exfoliation, functionalization, and size manipulation of graphene sheets: efficient system for biomedical applications

Comparative study of fractional CO2 laser and fractional CO2 laser-assisted drug delivery of topical steroid and topical vitamin C in macular amyloidosis

Photostimulation of osteogenic differentiation on silk scaffolds by plasma arc light source

Photobiomodulation therapy protects skeletal muscle and improves muscular function of mdx mice in a dose-dependent manner through modulation of dystrophin

Laser-induced autofluorescence-based objective evaluation of burn tissue repair in mice

Effects of corticopuncture (CP) and low-level laser therapy (LLLT) on the rate of tooth movement and root resorption in rats using micro-CT evaluation