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Techniques in Coloproctology
Erschienen in: Techniques in Coloproctology 3/2013

01.06.2013 | Review

The treatment of anal fistulas with biologically derived products: is innovation better than conventional surgical treatment? An update

verfasst von: Roberto Cirocchi, Stefano Trastulli, Umberto Morelli, Jacopo Desiderio, Carlo Boselli, Amilcare Parisi, Giuseppe Noya

Erschienen in: Techniques in Coloproctology | Ausgabe 3/2013

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Abstract

New technical approaches involving biologically derived products have been applied in the treatment for anal fistulas in order to avoid the risk of fecal incontinence. The aim of this review was to evaluate the scientific evidence present in the literature regarding these techniques. Trials comparing surgery (fistulotomy, advancement mucosal flap closure and placement of seton) versus fibrin glue, fistula plug or acellular dermal matrix were considered. In fibrin glue versus traditional surgical treatment the healing rate was higher in the surgery group, and the recurrence rate was lower in the traditional surgery group, but these results were not statistically relevant. In acellular dermal matrix (ADM) versus traditional surgical treatment the recurrence rate of fistulas was significantly lower in the ADM group, but non-significant differences were recorded in incontinence and anal deformity. Our review shows that there are no significant advantages of the new techniques involving biologically derived products. Further randomized controlled trials are needed.
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Metadaten
Titel
The treatment of anal fistulas with biologically derived products: is innovation better than conventional surgical treatment? An update
verfasst von
Roberto Cirocchi
Stefano Trastulli
Umberto Morelli
Jacopo Desiderio
Carlo Boselli
Amilcare Parisi
Giuseppe Noya
Publikationsdatum
01.06.2013
Verlag
Springer Milan
Erschienen in
Techniques in Coloproctology / Ausgabe 3/2013
Print ISSN: 1123-6337
Elektronische ISSN: 1128-045X
DOI
https://doi.org/10.1007/s10151-012-0948-9

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