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Erschienen in: Techniques in Coloproctology 8/2016

22.07.2016 | Original Article

Damage control strategy for the treatment of perforated diverticulitis with generalized peritonitis

verfasst von: M. Sohn, A. Agha, W. Heitland, F. Gundling, P. Steiner, I. Iesalnieks

Erschienen in: Techniques in Coloproctology | Ausgabe 8/2016

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Abstract

Background

The best surgical strategy for the management of perforated diverticulitis with generalized peritonitis of the sigmoid colon is not clearly defined. The aim of this retrospective cohort study was to evaluate the value of a damage control strategy.

Methods

All patients who underwent emergency laparotomy for perforated diverticular disease of the sigmoid colon with generalized peritonitis between 2010 and 2015 were included. The damage control strategy (study group), included a two- stage procedure: limited resection of the diseased colonic segment, closure of proximal colon and distal stump, and application of an abdominal vacuum at the initial surgery followed by second-look laparotomy 24–48 h later At this point a choice was made between anastomosis and Hartmann’s procedure. The control group consisted of patients receiving definitive reconstruction (anastomosis or Hartmann’s procedure) at the initial operation.

Results

Thirty-seven patients were included in the study. Damage control strategy was applied in 19 patients and the control group consisted of 18 patients. Both groups were comparable in terms of demographics, severity of peritonitis, and comorbidities. The overall postoperative mortality was 11 % (n = 4). There were no statistically significant differences between both groups regarding postoperative morbidity and mortality; however, a significantly higher proportion of patients in the control group had a stoma after the initial hospital stay (83 vs. 47 %, p = 0.038). This difference was still significant after adjustment for sex, age, Mannheim Peritonitis Index, American Society of Anesthesiologists class and presence of septic shock at presentation. At the end of the follow-up period, 15 of 17 survivors in the study group and 13 of 16 survivors in the control group had their intestinal continuity restored (p = 0.66).

Conclusions

Damage control strategy in patients with generalized peritonitis due to perforated diverticulitis leads to a significantly reduced stoma rate after the initial hospital stay without an increased risk of postoperative morbidity.
Literatur
1.
Zurück zum Zitat Holmer C, Kreis ME (2014) Diverticular disease—choice of surgical procedure. Chirurg 85:308–313CrossRefPubMed Holmer C, Kreis ME (2014) Diverticular disease—choice of surgical procedure. Chirurg 85:308–313CrossRefPubMed
2.
Zurück zum Zitat Aydin HN, Remzi FH, Tekkis PP, Fazio VW (2005) Hartmann’s reversal is associated with high postoperative adverse events. Dis Colon Rectum 48:2117–2126CrossRefPubMed Aydin HN, Remzi FH, Tekkis PP, Fazio VW (2005) Hartmann’s reversal is associated with high postoperative adverse events. Dis Colon Rectum 48:2117–2126CrossRefPubMed
3.
Zurück zum Zitat Vermeulen J, Coene PPLO, Van Hout NM et al (2009) Restoration of bowel continuity after surgery for acute perforated diverticulitis: should Hartmann’s procedure be considered a one-stage procedure? Colorectal Dis 11:619–624CrossRefPubMed Vermeulen J, Coene PPLO, Van Hout NM et al (2009) Restoration of bowel continuity after surgery for acute perforated diverticulitis: should Hartmann’s procedure be considered a one-stage procedure? Colorectal Dis 11:619–624CrossRefPubMed
4.
Zurück zum Zitat Oberkofler CE, Rickenbacher A, Raptis DA et al (2012) A multicenter randomized clinical trial of primary anastomosis or Hartmann’s procedure for perforated left colonic diverticulitis with purulent or fecal peritonitis. Ann Surg 256:819–826 (discussion 826–827) CrossRefPubMed Oberkofler CE, Rickenbacher A, Raptis DA et al (2012) A multicenter randomized clinical trial of primary anastomosis or Hartmann’s procedure for perforated left colonic diverticulitis with purulent or fecal peritonitis. Ann Surg 256:819–826 (discussion 826–827) CrossRefPubMed
5.
Zurück zum Zitat Vermeulen J, Lange JF (2010) Treatment of perforated diverticulitis with generalized peritonitis: past, present, and future. World J Surg 34:587–593CrossRefPubMedPubMedCentral Vermeulen J, Lange JF (2010) Treatment of perforated diverticulitis with generalized peritonitis: past, present, and future. World J Surg 34:587–593CrossRefPubMedPubMedCentral
6.
Zurück zum Zitat Kafka-Ritsch R, Birkfellner F, Perathoner A et al (2012) Damage control surgery with abdominal vacuum and delayed bowel reconstruction in patients with perforated diverticulitis Hinchey III/IV. J Gastrointest Surg 16:1915–1922CrossRefPubMed Kafka-Ritsch R, Birkfellner F, Perathoner A et al (2012) Damage control surgery with abdominal vacuum and delayed bowel reconstruction in patients with perforated diverticulitis Hinchey III/IV. J Gastrointest Surg 16:1915–1922CrossRefPubMed
7.
Zurück zum Zitat Perathoner A, Klaus A, Mühlmann G, Oberwalder M, Margreiter R, Kafka-Ritsch R (2010) Damage control with abdominal vacuum therapy (VAC) to manage perforated diverticulitis with advanced generalized peritonitis—a proof of concept. Int J Colorectal Dis 25:767–774CrossRefPubMed Perathoner A, Klaus A, Mühlmann G, Oberwalder M, Margreiter R, Kafka-Ritsch R (2010) Damage control with abdominal vacuum therapy (VAC) to manage perforated diverticulitis with advanced generalized peritonitis—a proof of concept. Int J Colorectal Dis 25:767–774CrossRefPubMed
8.
Zurück zum Zitat Cirocchi R, Arezzo A, Vettoretto N et al (2014) Role of damage control surgery in the treatment of Hinchey III and IV sigmoid diverticulitis: a tailored strategy. Medicine 93:e184CrossRefPubMedPubMedCentral Cirocchi R, Arezzo A, Vettoretto N et al (2014) Role of damage control surgery in the treatment of Hinchey III and IV sigmoid diverticulitis: a tailored strategy. Medicine 93:e184CrossRefPubMedPubMedCentral
9.
Zurück zum Zitat Langenfeld SJ (2013) Mandatory exploration is not necessary for patients with acute diverticulitis and free intraperitoneal air. J Trauma Acute Care Surg 74:1376CrossRefPubMed Langenfeld SJ (2013) Mandatory exploration is not necessary for patients with acute diverticulitis and free intraperitoneal air. J Trauma Acute Care Surg 74:1376CrossRefPubMed
10.
Zurück zum Zitat Rogy M, Függer R, Schemper M, Koss G, Schulz F (1990) The value of 2 distinct prognosis scores in patients with peritonitis. The Mannheim Peritonitis Index versus the Apache II score. Chirurg 61:297–300PubMed Rogy M, Függer R, Schemper M, Koss G, Schulz F (1990) The value of 2 distinct prognosis scores in patients with peritonitis. The Mannheim Peritonitis Index versus the Apache II score. Chirurg 61:297–300PubMed
11.
Zurück zum Zitat Függer R, Rogy M, Herbst F, Schemper M, Schulz F (1988) Validation study of the Mannheim Peritonitis Index. Chirurg 59:598–601PubMed Függer R, Rogy M, Herbst F, Schemper M, Schulz F (1988) Validation study of the Mannheim Peritonitis Index. Chirurg 59:598–601PubMed
12.
Zurück zum Zitat Demmel N, Muth G, Maag K, Osterholzer G (1994) Prognostic scores in peritonitis: the Mannheim Peritonitis Index or APACHE II? Langenbecks Arch Chir 379:347–352PubMed Demmel N, Muth G, Maag K, Osterholzer G (1994) Prognostic scores in peritonitis: the Mannheim Peritonitis Index or APACHE II? Langenbecks Arch Chir 379:347–352PubMed
13.
Zurück zum Zitat Dindo D, Demartines N, Clavien P-A (2004) Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240:205–213CrossRefPubMedPubMedCentral Dindo D, Demartines N, Clavien P-A (2004) Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240:205–213CrossRefPubMedPubMedCentral
14.
Zurück zum Zitat Binda GA, Karas JR, Serventi A, Study Group on Diverticulitis et al (2012) Primary anastomosis vs nonrestorative resection for perforated diverticulitis with peritonitis: a prematurely terminated randomized controlled trial. Colorectal Dis 14:1403–1410CrossRefPubMed Binda GA, Karas JR, Serventi A, Study Group on Diverticulitis et al (2012) Primary anastomosis vs nonrestorative resection for perforated diverticulitis with peritonitis: a prematurely terminated randomized controlled trial. Colorectal Dis 14:1403–1410CrossRefPubMed
15.
Zurück zum Zitat Cirocchi R, Trastulli S, Desiderio J et al (2013) Treatment of Hinchey stage III-IV diverticulitis: a systematic review and meta-analysis. Int J Colorectal Dis 28:447–457CrossRefPubMed Cirocchi R, Trastulli S, Desiderio J et al (2013) Treatment of Hinchey stage III-IV diverticulitis: a systematic review and meta-analysis. Int J Colorectal Dis 28:447–457CrossRefPubMed
16.
Zurück zum Zitat O’Sullivan GC, Murphy D, O’Brien MG, Ireland A (1996) Laparoscopic management of generalized peritonitis due to perforated colonic diverticula. Am J Surg 171:432–434CrossRefPubMed O’Sullivan GC, Murphy D, O’Brien MG, Ireland A (1996) Laparoscopic management of generalized peritonitis due to perforated colonic diverticula. Am J Surg 171:432–434CrossRefPubMed
17.
Zurück zum Zitat Myers E, Hurley M, O’Sullivan GC, Kavanagh D, Wilson I, Winter DC (2008) Laparoscopic peritoneal lavage for generalized peritonitis due to perforated diverticulitis. Br J Surg 95:97–101CrossRefPubMed Myers E, Hurley M, O’Sullivan GC, Kavanagh D, Wilson I, Winter DC (2008) Laparoscopic peritoneal lavage for generalized peritonitis due to perforated diverticulitis. Br J Surg 95:97–101CrossRefPubMed
18.
Zurück zum Zitat Toorenvliet BR, Swank H, Schoones JW, Hamming JF, Bemelman WA (2010) Laparoscopic peritoneal lavage for perforated colonic diverticulitis: a systematic review. Colorectal Dis 12:862–867CrossRefPubMed Toorenvliet BR, Swank H, Schoones JW, Hamming JF, Bemelman WA (2010) Laparoscopic peritoneal lavage for perforated colonic diverticulitis: a systematic review. Colorectal Dis 12:862–867CrossRefPubMed
19.
Zurück zum Zitat Angenete E, Thornell A, Burcharth J et al (2014) Laparoscopic lavage is feasible and safe for the treatment of perforated diverticulitis with purulent peritonitis: the first results from the randomized controlled trial DILALA. Ann Surg 263:117–122CrossRef Angenete E, Thornell A, Burcharth J et al (2014) Laparoscopic lavage is feasible and safe for the treatment of perforated diverticulitis with purulent peritonitis: the first results from the randomized controlled trial DILALA. Ann Surg 263:117–122CrossRef
20.
Zurück zum Zitat Swank HA, Vermeulen J, Lange JF, Dutch Diverticular Disease (3D) Collaborative Study Group et al (2010) The ladies trial: laparoscopic peritoneal lavage or resection for purulent peritonitis and Hartmann’s procedure or resection with primary anastomosis for purulent or faecal peritonitis in perforated diverticulitis (NTR2037). BMC Surg 10:29CrossRefPubMedPubMedCentral Swank HA, Vermeulen J, Lange JF, Dutch Diverticular Disease (3D) Collaborative Study Group et al (2010) The ladies trial: laparoscopic peritoneal lavage or resection for purulent peritonitis and Hartmann’s procedure or resection with primary anastomosis for purulent or faecal peritonitis in perforated diverticulitis (NTR2037). BMC Surg 10:29CrossRefPubMedPubMedCentral
21.
Zurück zum Zitat Vennix S, Musters GD, Mulder IM, Ladies trial colloborators et al (2015) Laparoscopic peritoneal lavage or sigmoidectomy for perforated diverticulitis with purulent peritonitis: a multicentre, parallel-group, randomised, open-label trial. Lancet 386:1269–1277CrossRefPubMed Vennix S, Musters GD, Mulder IM, Ladies trial colloborators et al (2015) Laparoscopic peritoneal lavage or sigmoidectomy for perforated diverticulitis with purulent peritonitis: a multicentre, parallel-group, randomised, open-label trial. Lancet 386:1269–1277CrossRefPubMed
22.
Zurück zum Zitat Schultz JK, Yaqub S, Wallon C, SCANDIV Study Group et al (2015) Laparoscopic lavage vs primary resection for acute perforated diverticulitis: the SCANDIV randomized clinical trial. JAMA 314:1364–1375CrossRefPubMed Schultz JK, Yaqub S, Wallon C, SCANDIV Study Group et al (2015) Laparoscopic lavage vs primary resection for acute perforated diverticulitis: the SCANDIV randomized clinical trial. JAMA 314:1364–1375CrossRefPubMed
Metadaten
Titel
Damage control strategy for the treatment of perforated diverticulitis with generalized peritonitis
verfasst von
M. Sohn
A. Agha
W. Heitland
F. Gundling
P. Steiner
I. Iesalnieks
Publikationsdatum
22.07.2016
Verlag
Springer Milan
Erschienen in
Techniques in Coloproctology / Ausgabe 8/2016
Print ISSN: 1123-6337
Elektronische ISSN: 1128-045X
DOI
https://doi.org/10.1007/s10151-016-1506-7

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