Skip to main content
Erschienen in: Techniques in Coloproctology 12/2016

25.11.2016 | Review

Transanal hemorrhoidal dearterialization with mucopexy versus open hemorrhoidectomy in the treatment of hemorrhoids: a meta-analysis of randomized control trials

verfasst von: L. Xu, H. Chen, G. Lin, Q. Ge, H. Qi, X. He

Erschienen in: Techniques in Coloproctology | Ausgabe 12/2016

Einloggen, um Zugang zu erhalten

Abstract

Background

The aim of this study was to analyse the outcomes of transanal hemorrhoidal dearterialization with mucopexy (THDm) versus open hemorrhoidectomy (OH) in the management of hemorrhoids.

Methods

Randomized controlled trials in English were found by searching PubMed, Web of science, EMBASE, and the Cochrane Library database. Trials that compared THDm with OH were identified. Data were extracted independently for each study, and a meta-analysis was performed using fixed and random effects models.

Results

Four trials, including 316 patients, met the inclusion criteria. No statistically significant differences were noted in either total complications or postoperative bleeding, incontinence, recurrent prolapse, and urinary retention rate. Operative time was significantly longer for THDm with Doppler guidance than for THDm without Doppler guidance. Patients returned to normal activities faster after THDm than after OH. No statistically significant differences between THDm and OH were noted with regard to recurrence and reoperation rates.

Conclusions

Our meta-analysis shows that THDm and OH are equally effective and can be attempted for the management of hemorrhoids. However, for THDm with Doppler guidance, more instruments and a longer operative time are required. Future large-scale, high-quality, multicenter trials with long-term outcomes are needed to prove these results and determine whether Doppler guidance in THD is truly necessary or not.
Literatur
1.
Zurück zum Zitat LaBella GD, Main WP, Hussain LR (2015) Evaluation of transanal hemorrhoidal dearterialization: a single surgeon experience. Tech Coloproctol 19:153–157CrossRefPubMedPubMedCentral LaBella GD, Main WP, Hussain LR (2015) Evaluation of transanal hemorrhoidal dearterialization: a single surgeon experience. Tech Coloproctol 19:153–157CrossRefPubMedPubMedCentral
2.
Zurück zum Zitat Chen HL, Woo XB, Cui J, Chen CQ, Peng JS (2014) Ligasure versus stapled hemorrhoidectomy in the treatment of hemorrhoids: a meta-analysis of randomized control trials. Surg Laparosc Endosc Percutan Tech 24:285–289CrossRefPubMed Chen HL, Woo XB, Cui J, Chen CQ, Peng JS (2014) Ligasure versus stapled hemorrhoidectomy in the treatment of hemorrhoids: a meta-analysis of randomized control trials. Surg Laparosc Endosc Percutan Tech 24:285–289CrossRefPubMed
3.
Zurück zum Zitat Picchio M, Palimento D, Attanasio U, Renda A (2006) Stapled vs open hemorrhoidectomy: long-term outcome of a randomized controlled trial. Int J Colorectal Dis 21:668–669CrossRefPubMed Picchio M, Palimento D, Attanasio U, Renda A (2006) Stapled vs open hemorrhoidectomy: long-term outcome of a randomized controlled trial. Int J Colorectal Dis 21:668–669CrossRefPubMed
4.
Zurück zum Zitat Xu L, Chen H, Lin G, Ge Q (2015) Ligasure versus ferguson hemorrhoidectomy in the treatment of hemorrhoids: a meta-analysis of randomized control trials. Surg Laparosc Endosc Percutan Tech 25:106–110CrossRefPubMed Xu L, Chen H, Lin G, Ge Q (2015) Ligasure versus ferguson hemorrhoidectomy in the treatment of hemorrhoids: a meta-analysis of randomized control trials. Surg Laparosc Endosc Percutan Tech 25:106–110CrossRefPubMed
5.
Zurück zum Zitat Maloku H, Gashi Z, Lazovic R, Islami H, Juniku-Shkololli A (2014) Laser hemorrhoidoplasty procedure vs open surgical hemorrhoidectomy: a trial comparing 2 treatments for hemorrhoids of third and fourth degree. Acta Inform Med 22:365–367CrossRefPubMedPubMedCentral Maloku H, Gashi Z, Lazovic R, Islami H, Juniku-Shkololli A (2014) Laser hemorrhoidoplasty procedure vs open surgical hemorrhoidectomy: a trial comparing 2 treatments for hemorrhoids of third and fourth degree. Acta Inform Med 22:365–367CrossRefPubMedPubMedCentral
6.
Zurück zum Zitat Hoyuela C, Carvajal F, Juvany M et al (2016) HAL-RAR (Doppler guided haemorrhoid artery ligation with recto-anal repair) is a safe and effective procedure for haemorrhoids. Results of a prospective study after two-years follow-up. Int J Colorectal Dis 28:39–44 Hoyuela C, Carvajal F, Juvany M et al (2016) HAL-RAR (Doppler guided haemorrhoid artery ligation with recto-anal repair) is a safe and effective procedure for haemorrhoids. Results of a prospective study after two-years follow-up. Int J Colorectal Dis 28:39–44
7.
Zurück zum Zitat Morinaga K, Hasuda K, Ikeda T (1995) A novel therapy for internal hemorrhoids: ligation of the hemorrhoidal artery with a newly devised instrument (Moricorn) in conjunction with a Doppler flowmeter. Am J Gastroenterol 90:610–613PubMed Morinaga K, Hasuda K, Ikeda T (1995) A novel therapy for internal hemorrhoids: ligation of the hemorrhoidal artery with a newly devised instrument (Moricorn) in conjunction with a Doppler flowmeter. Am J Gastroenterol 90:610–613PubMed
8.
Zurück zum Zitat Chayama K, Tsubota A, Arase Y et al (1995) Genotype, slow decrease in virus titer during interferon treatment and high degree of sequence variability of hypervariable region are indicative of poor response to interferon treatment in patients with chronic hepatitis type C. J Hepatol 23:648–653CrossRefPubMed Chayama K, Tsubota A, Arase Y et al (1995) Genotype, slow decrease in virus titer during interferon treatment and high degree of sequence variability of hypervariable region are indicative of poor response to interferon treatment in patients with chronic hepatitis type C. J Hepatol 23:648–653CrossRefPubMed
9.
Zurück zum Zitat Gravie JF (2014) Hemorrhoidal arterial ligation with mucopexy: a risk-free technique? J Visc Surg 151:421–422CrossRefPubMed Gravie JF (2014) Hemorrhoidal arterial ligation with mucopexy: a risk-free technique? J Visc Surg 151:421–422CrossRefPubMed
10.
Zurück zum Zitat Ratto C, de Parades V (2014) Doppler-guided ligation of hemorrhoidal arteries with mucopexy: a technique for the future. J Visc Surg 152:S15–S21CrossRefPubMed Ratto C, de Parades V (2014) Doppler-guided ligation of hemorrhoidal arteries with mucopexy: a technique for the future. J Visc Surg 152:S15–S21CrossRefPubMed
11.
Zurück zum Zitat Jadad AR, Carroll D, Jenkinson C, Reynolds DJ, Gavaghan DJ, McQuay HJ (1996) Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials 17:1–12CrossRefPubMed Jadad AR, Carroll D, Jenkinson C, Reynolds DJ, Gavaghan DJ, McQuay HJ (1996) Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials 17:1–12CrossRefPubMed
12.
Zurück zum Zitat Elmér SE, Nygren JO, Lenander CE (2013) A randomized trial of transanal hemorrhoidal dearterialization with anopexy compared with open hemorrhoidectomy in the treatment of hemorrhoids. Dis Colon Rectum 56:484–490CrossRefPubMed Elmér SE, Nygren JO, Lenander CE (2013) A randomized trial of transanal hemorrhoidal dearterialization with anopexy compared with open hemorrhoidectomy in the treatment of hemorrhoids. Dis Colon Rectum 56:484–490CrossRefPubMed
13.
Zurück zum Zitat De Nardi P, Capretti G, Corsaro A, Staudacher C (2014) A prospective, randomized trial comparing the short- and long-term results of doppler-guided transanal hemorrhoid dearterialization with mucopexy versus excision hemorrhoidectomy for grade III hemorrhoids. Dis Colon Rectum 57:348–353CrossRefPubMed De Nardi P, Capretti G, Corsaro A, Staudacher C (2014) A prospective, randomized trial comparing the short- and long-term results of doppler-guided transanal hemorrhoid dearterialization with mucopexy versus excision hemorrhoidectomy for grade III hemorrhoids. Dis Colon Rectum 57:348–353CrossRefPubMed
14.
Zurück zum Zitat Denoya P, Tam J, Bergamaschi R (2014) Hemorrhoidal dearterialization with mucopexy versus hemorrhoidectomy: 3-year follow-up assessment of a randomized controlled trial. Tech Coloproctol 18:1081–1085CrossRefPubMedPubMedCentral Denoya P, Tam J, Bergamaschi R (2014) Hemorrhoidal dearterialization with mucopexy versus hemorrhoidectomy: 3-year follow-up assessment of a randomized controlled trial. Tech Coloproctol 18:1081–1085CrossRefPubMedPubMedCentral
15.
Zurück zum Zitat Elshazly WG, Gazal AE, Madbouly K, Hussen A (2015) Ligation anopexy versus hemorrhoidectomy in the treatment of second- and third-degree hemorrhoids. Tech Coloproctol 19:29–34CrossRefPubMed Elshazly WG, Gazal AE, Madbouly K, Hussen A (2015) Ligation anopexy versus hemorrhoidectomy in the treatment of second- and third-degree hemorrhoids. Tech Coloproctol 19:29–34CrossRefPubMed
16.
Zurück zum Zitat Talha A, Bessa S, Abdel Wahab M (2014) Ligasure, Harmonic Scalpel versus conventional diathermy in excisional haemorrhoidectomy: a randomized controlled trial. ANZ J Surg. doi:10.1111/ans.12838 PubMed Talha A, Bessa S, Abdel Wahab M (2014) Ligasure, Harmonic Scalpel versus conventional diathermy in excisional haemorrhoidectomy: a randomized controlled trial. ANZ J Surg. doi:10.​1111/​ans.​12838 PubMed
17.
Zurück zum Zitat Arnold S, Antonietti E, Rollinger G, Scheyer M (2002) Doppler ultrasound assisted hemorrhoid artery ligation. A new therapy in symptomatic hemorrhoids. Chirurg 73:269–273CrossRefPubMed Arnold S, Antonietti E, Rollinger G, Scheyer M (2002) Doppler ultrasound assisted hemorrhoid artery ligation. A new therapy in symptomatic hemorrhoids. Chirurg 73:269–273CrossRefPubMed
18.
Zurück zum Zitat Bursics A, Morvay K, Kupcsulik P, Flautner L (2004) Comparison of early and 1-year follow-up results of conventional hemorrhoidectomy and hemorrhoid artery ligation: a randomized study. Int J Colorectal Dis 19:176–180CrossRefPubMed Bursics A, Morvay K, Kupcsulik P, Flautner L (2004) Comparison of early and 1-year follow-up results of conventional hemorrhoidectomy and hemorrhoid artery ligation: a randomized study. Int J Colorectal Dis 19:176–180CrossRefPubMed
19.
Zurück zum Zitat Takenoshita S, Hashizume T, Asao T et al (1995) Efficacy of immunochemotherapy with Ftorafur and Krestin in rats. Anticancer Res 15:147–151PubMed Takenoshita S, Hashizume T, Asao T et al (1995) Efficacy of immunochemotherapy with Ftorafur and Krestin in rats. Anticancer Res 15:147–151PubMed
20.
Zurück zum Zitat Giordano P, Tomasi I, Pascariello A, Mills E, Elahi S (2014) Transanal dearterialization with targeted mucopexy is effective for advanced haemorrhoids. Colorectal Dis 16:373–376CrossRefPubMedPubMedCentral Giordano P, Tomasi I, Pascariello A, Mills E, Elahi S (2014) Transanal dearterialization with targeted mucopexy is effective for advanced haemorrhoids. Colorectal Dis 16:373–376CrossRefPubMedPubMedCentral
21.
Zurück zum Zitat Ruhm W, Kato K, Korschinek G, Morinaga H, Nolte E (1995) Neutron spectrum and yield of the Hiroshima A-bomb deduced from radionuclide measurements at one location. Int J Radiat Biol 68:97–103CrossRefPubMed Ruhm W, Kato K, Korschinek G, Morinaga H, Nolte E (1995) Neutron spectrum and yield of the Hiroshima A-bomb deduced from radionuclide measurements at one location. Int J Radiat Biol 68:97–103CrossRefPubMed
22.
Zurück zum Zitat Yoh M, Morinaga N, Noda M, Honda T (1995) The binding of Vibrio parahaemolyticus 125I-labeled thermostable directhemolysin to erythrocytes. Toxicon 33:651–657CrossRefPubMed Yoh M, Morinaga N, Noda M, Honda T (1995) The binding of Vibrio parahaemolyticus 125I-labeled thermostable directhemolysin to erythrocytes. Toxicon 33:651–657CrossRefPubMed
23.
Zurück zum Zitat Fujiwara M, Mizoguchi H, Kawamura J et al (1995) A new endotracheal tube with a cuff impervious to nitrous oxide: constancy of cuff pressure and volume. Anesth Analg 81:1084–1086PubMed Fujiwara M, Mizoguchi H, Kawamura J et al (1995) A new endotracheal tube with a cuff impervious to nitrous oxide: constancy of cuff pressure and volume. Anesth Analg 81:1084–1086PubMed
24.
Zurück zum Zitat Nomori H, Horio H, Kobayashi R, Morinaga S, Hirabayashi Y (1995) Protein 1 (Clara cell protein) serum levels in lung cancer patients receiving chemotherapy. Eur Respir J 8:1654–1657CrossRefPubMed Nomori H, Horio H, Kobayashi R, Morinaga S, Hirabayashi Y (1995) Protein 1 (Clara cell protein) serum levels in lung cancer patients receiving chemotherapy. Eur Respir J 8:1654–1657CrossRefPubMed
25.
Zurück zum Zitat Giamundo P, Cecchetti W, Esercizio L et al (2011) Doppler-guided hemorrhoidal laser procedure for the treatment of symptomatic hemorrhoids: experimental background and short-term clinical results of a new mini-invasive treatment. Surg Endosc 25:1369–1375CrossRefPubMed Giamundo P, Cecchetti W, Esercizio L et al (2011) Doppler-guided hemorrhoidal laser procedure for the treatment of symptomatic hemorrhoids: experimental background and short-term clinical results of a new mini-invasive treatment. Surg Endosc 25:1369–1375CrossRefPubMed
26.
Zurück zum Zitat Faucheron JL, Poncet G, Voirin D, Badic B, Gangner Y (2011) Doppler-guided hemorrhoidal artery ligation and rectoanal repair (HAL-RAR) for the treatment of grade IV hemorrhoids: long-term results in 100 consecutive patients. Dis Colon Rectum 54:226–231CrossRefPubMed Faucheron JL, Poncet G, Voirin D, Badic B, Gangner Y (2011) Doppler-guided hemorrhoidal artery ligation and rectoanal repair (HAL-RAR) for the treatment of grade IV hemorrhoids: long-term results in 100 consecutive patients. Dis Colon Rectum 54:226–231CrossRefPubMed
27.
Zurück zum Zitat Giordano P, Nastro P, Davies A, Gravante G (2011) Prospective evaluation of stapled haemorrhoidopexy versus transanal haemorrhoidal dearterialisation for stage II and III haemorrhoids: three-year outcomes. Tech Coloproctol 15:67–73CrossRefPubMedPubMedCentral Giordano P, Nastro P, Davies A, Gravante G (2011) Prospective evaluation of stapled haemorrhoidopexy versus transanal haemorrhoidal dearterialisation for stage II and III haemorrhoids: three-year outcomes. Tech Coloproctol 15:67–73CrossRefPubMedPubMedCentral
28.
Zurück zum Zitat Lopez-Delgado A, Arroyo A, Ruiz-Tovar J et al (2014) Effect on anal pressure of percutaneous posterior tibial nerve stimulation for faecal incontinence. Colorectal Dis 16:533–537CrossRefPubMed Lopez-Delgado A, Arroyo A, Ruiz-Tovar J et al (2014) Effect on anal pressure of percutaneous posterior tibial nerve stimulation for faecal incontinence. Colorectal Dis 16:533–537CrossRefPubMed
29.
Zurück zum Zitat Morinaga T, Fujii S, Kikumori M, Nishimori T, Watanabe M, Sumi N (1995) Reproductive and developmental toxicity studies of montirelin hydrate (4) Perinatal and postnatal study in rats by intravenous administration. J Toxicol Sci 20((Suppl 2)):309–323CrossRefPubMed Morinaga T, Fujii S, Kikumori M, Nishimori T, Watanabe M, Sumi N (1995) Reproductive and developmental toxicity studies of montirelin hydrate (4) Perinatal and postnatal study in rats by intravenous administration. J Toxicol Sci 20((Suppl 2)):309–323CrossRefPubMed
Metadaten
Titel
Transanal hemorrhoidal dearterialization with mucopexy versus open hemorrhoidectomy in the treatment of hemorrhoids: a meta-analysis of randomized control trials
verfasst von
L. Xu
H. Chen
G. Lin
Q. Ge
H. Qi
X. He
Publikationsdatum
25.11.2016
Verlag
Springer International Publishing
Erschienen in
Techniques in Coloproctology / Ausgabe 12/2016
Print ISSN: 1123-6337
Elektronische ISSN: 1128-045X
DOI
https://doi.org/10.1007/s10151-016-1551-2

Weitere Artikel der Ausgabe 12/2016

Techniques in Coloproctology 12/2016 Zur Ausgabe

From the innovation in colorectal surgery editor

How Twitter has connected the colorectal community

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

CME: 2 Punkte

Prof. Dr. med. Gregor Antoniadis Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

CME: 2 Punkte

Dr. med. Benjamin Meyknecht, PD Dr. med. Oliver Pieske Das Webinar S2e-Leitlinie „Distale Radiusfraktur“ beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

CME: 2 Punkte

Dr. med. Mihailo Andric
Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.