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Erschienen in: Techniques in Coloproctology 1/2018

18.12.2017 | Original Article

Early outcomes of fluorescence angiography in the setting of endorectal mucosa advancement flaps

verfasst von: J. S. Turner, A. Okonkwo, A. Chase, C. E. Clark

Erschienen in: Techniques in Coloproctology | Ausgabe 1/2018

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Abstract

Background

Fistula-in-ano has a reported incidence of 31–34%. Besides fistulotomy, options for fistula repair are seton placement, endorectal advancement flap (ERAF), fibrin sealant, anal fistula plug and ligation of the intersphincteric fistula tract. Despite having a reported success rate as high as 75–98%, ERAF is not without complications, including flap breakdown, recurrence and fecal incontinence. Traditionally, maintaining a broad base to preserve blood supply has been advocated to reduce flap failure. And the aim of the present study was to evaluate outcomes of adult patients who underwent ERAF for complex fistula-in-ano with the use of intraoperative fluorescence angiography (FA) at our institution between July 2014 and July 2016.

Methods

We retrospectively reviewed consecutive cases of complex fistula-in-ano repair with ERAF and FA from a prospectively maintained dataset of adult patients with complex fistula-in-ano. Demographics, intraoperative data and 60-day outcomes were recorded and reviewed.

Results

Six patients [five males and one female with a mean age of 40 years (range 25–46 years)], with a total of seven fistulas, were identified. Six (85.7%) of these patients had undergone prior surgery for fistula-in-ano. No recurrences or complications of any type were noted at 2-week and 8-week follow-up. The majority of patients (71.4%) required flap revision based on intraoperative FA prior to flap fixation.

Conclusions

FA is safe and offers real-time assessment of flap perfusion prior to and after fixation in anal fistula repair. The rate of flap ischemia may be underestimated, and therefore, to improve outcomes in ERAF, intraoperative FA should be included in the surgical armamentarium.
Literatur
1.
Zurück zum Zitat Lohsiriwat V, Yodying H, Lohsiriwat D (2010) Incidence and factors influencing the development of fistula-in-ano after incision and drainage of perianal abscesses. J Med Assoc Thail 93(1):61–65 Lohsiriwat V, Yodying H, Lohsiriwat D (2010) Incidence and factors influencing the development of fistula-in-ano after incision and drainage of perianal abscesses. J Med Assoc Thail 93(1):61–65
2.
Zurück zum Zitat Ramanujam PS, Prasad ML, Abcarian H, Tan AB (1984) Perianal abscesses and fistulas. A study of 1023 patients. 2. Dis Colon Rectum 27(9):593–597CrossRefPubMed Ramanujam PS, Prasad ML, Abcarian H, Tan AB (1984) Perianal abscesses and fistulas. A study of 1023 patients. 2. Dis Colon Rectum 27(9):593–597CrossRefPubMed
3.
Zurück zum Zitat Farmer RG, Hawk WA, Turnbull RB Jr (1975) Clinical patterns in Crohn’s disease: a statistical study of 615 cases. Gastroenterology 68(4 Pt 1):627–635PubMed Farmer RG, Hawk WA, Turnbull RB Jr (1975) Clinical patterns in Crohn’s disease: a statistical study of 615 cases. Gastroenterology 68(4 Pt 1):627–635PubMed
4.
Zurück zum Zitat Visscher AP, Schuur D, Roos R et al (2015) Long-term follow-up after surgery for simple and complex cryptoglandular fistulas: fecal incontinence and impact on quality of life. Dis Colon Rectum 58(5):533–539CrossRefPubMed Visscher AP, Schuur D, Roos R et al (2015) Long-term follow-up after surgery for simple and complex cryptoglandular fistulas: fecal incontinence and impact on quality of life. Dis Colon Rectum 58(5):533–539CrossRefPubMed
5.
Zurück zum Zitat Hämäläinen KP, Sainio AP (1997) Cutting seton for anal fistulas: high risk of minor control defects. Dis Colon Rectum 40(12):1443–1446CrossRefPubMed Hämäläinen KP, Sainio AP (1997) Cutting seton for anal fistulas: high risk of minor control defects. Dis Colon Rectum 40(12):1443–1446CrossRefPubMed
6.
Zurück zum Zitat Blumetti J, Abcarian A, Quinteros F et al (2012) Evolution of treatment of fistula-in-ano. World J Surg 36(5):1162–1167CrossRefPubMed Blumetti J, Abcarian A, Quinteros F et al (2012) Evolution of treatment of fistula-in-ano. World J Surg 36(5):1162–1167CrossRefPubMed
7.
Zurück zum Zitat Göttgens KW, Smeets RR, Stassen LP et al (2015) Systematic review and meta-analysis of surgical interventions for high cryptoglandular perianal fistula. Int J Colorectal Dis 30(5):583–593CrossRefPubMed Göttgens KW, Smeets RR, Stassen LP et al (2015) Systematic review and meta-analysis of surgical interventions for high cryptoglandular perianal fistula. Int J Colorectal Dis 30(5):583–593CrossRefPubMed
10.
Zurück zum Zitat Ommer A, Wenger FA, Rolfs T et al (2008) Continence disorders after anal surgery–a relevant problem? Int J Colorectal Dis 23(11):1023–1031CrossRefPubMed Ommer A, Wenger FA, Rolfs T et al (2008) Continence disorders after anal surgery–a relevant problem? Int J Colorectal Dis 23(11):1023–1031CrossRefPubMed
11.
Zurück zum Zitat Golub RW, Wise WE Jr, Kerner BA et al (1997) Endorectal mucosal advancement flap: the preferred method for complex cryptoglandular fistula-in-ano. J Gastrointest Surg 1(5):487–491CrossRefPubMed Golub RW, Wise WE Jr, Kerner BA et al (1997) Endorectal mucosal advancement flap: the preferred method for complex cryptoglandular fistula-in-ano. J Gastrointest Surg 1(5):487–491CrossRefPubMed
12.
Zurück zum Zitat Soltani A, Kaiser AM (2010) Endorectal advancement flap for cryptoglandular or Crohn’s fistula-in-ano. Dis Colon Rectum 53(4):486–495CrossRefPubMed Soltani A, Kaiser AM (2010) Endorectal advancement flap for cryptoglandular or Crohn’s fistula-in-ano. Dis Colon Rectum 53(4):486–495CrossRefPubMed
13.
Zurück zum Zitat Sonoda T, Hull T, Piedmonte MR et al (2002) Outcomes of primary repair of anorectal and rectovaginal fistulas using the endorectal advancement flap. Dis Colon Rectum 45(12):1622–1628CrossRefPubMed Sonoda T, Hull T, Piedmonte MR et al (2002) Outcomes of primary repair of anorectal and rectovaginal fistulas using the endorectal advancement flap. Dis Colon Rectum 45(12):1622–1628CrossRefPubMed
14.
Zurück zum Zitat Jarrar A, Church J (2011) Advancement flap repair: a good option for complex anorectal fistulas. Dis Colon Rectum 54(12):1537–1541CrossRefPubMed Jarrar A, Church J (2011) Advancement flap repair: a good option for complex anorectal fistulas. Dis Colon Rectum 54(12):1537–1541CrossRefPubMed
15.
Zurück zum Zitat Fisher OM, Raptis DA, Vetter D et al (2015) An outcome and cost analysis of anal fistula plug insertion vs endorectal advancement flap for complex anal fistulae. Colorectal Dis 17(7):619–626CrossRefPubMed Fisher OM, Raptis DA, Vetter D et al (2015) An outcome and cost analysis of anal fistula plug insertion vs endorectal advancement flap for complex anal fistulae. Colorectal Dis 17(7):619–626CrossRefPubMed
16.
Zurück zum Zitat Tan KK, Alsuwaigh R, Tan AM et al (2012) To LIFT or to flap? Which surgery to perform following seton insertion for high anal fistula? Dis Colon Rectum 55(12):1273–1277CrossRefPubMed Tan KK, Alsuwaigh R, Tan AM et al (2012) To LIFT or to flap? Which surgery to perform following seton insertion for high anal fistula? Dis Colon Rectum 55(12):1273–1277CrossRefPubMed
17.
Zurück zum Zitat Stremitzer S, Riss S, Swoboda P et al (2012) Repeat endorectal advancement flap after flap breakdown and recurrence of fistula-in-ano–is it an option? Colorectal Dis 14(11):1389–1393CrossRefPubMed Stremitzer S, Riss S, Swoboda P et al (2012) Repeat endorectal advancement flap after flap breakdown and recurrence of fistula-in-ano–is it an option? Colorectal Dis 14(11):1389–1393CrossRefPubMed
18.
Zurück zum Zitat Mizrahi N, Wexner SD, Zmora O et al (2002) Endorectal advancement flap: are there predictors of failure? Dis Colon Rectum 45(12):1616–1621CrossRefPubMed Mizrahi N, Wexner SD, Zmora O et al (2002) Endorectal advancement flap: are there predictors of failure? Dis Colon Rectum 45(12):1616–1621CrossRefPubMed
19.
Zurück zum Zitat Jones IT, Fazio VW, Jagelman DG (1987) The use of transanal rectal advancement flaps in the management of fistulas involving the anorectum. Dis Colon Rectum 30(12):919–923CrossRefPubMed Jones IT, Fazio VW, Jagelman DG (1987) The use of transanal rectal advancement flaps in the management of fistulas involving the anorectum. Dis Colon Rectum 30(12):919–923CrossRefPubMed
20.
Zurück zum Zitat Christoforidis D, Pieh MC, Madoff RD, Mellgren AF (2009) Treatment of transsphincteric anal fistulas by endorectal advancement flap or collagen fistula plug: a comparative study. Dis Colon Rectum 52:18–22CrossRefPubMed Christoforidis D, Pieh MC, Madoff RD, Mellgren AF (2009) Treatment of transsphincteric anal fistulas by endorectal advancement flap or collagen fistula plug: a comparative study. Dis Colon Rectum 52:18–22CrossRefPubMed
21.
23.
Zurück zum Zitat Jafari MD, Wexner SD, Martz JE et al (2015) Perfusion assessment in laparoscopic left sided/anterior resection (PILLAR II): a multi-institutional study. J Am Coll Surg 220:82–92CrossRefPubMed Jafari MD, Wexner SD, Martz JE et al (2015) Perfusion assessment in laparoscopic left sided/anterior resection (PILLAR II): a multi-institutional study. J Am Coll Surg 220:82–92CrossRefPubMed
24.
Zurück zum Zitat Atallah SB, Albert MR, de Beche-Adams TC et al (2013) Application of laser-assisted indocyanine green fluorescent angiography for the assessment of tissue perfusion of anodermal advancement flaps. Dis Colon Rectum 56:797CrossRefPubMed Atallah SB, Albert MR, de Beche-Adams TC et al (2013) Application of laser-assisted indocyanine green fluorescent angiography for the assessment of tissue perfusion of anodermal advancement flaps. Dis Colon Rectum 56:797CrossRefPubMed
25.
Zurück zum Zitat Turner J, Clark C (2016) Fluorescence imaging in anorectal advancement flaps. Dis Colon Rectum 59(7):700CrossRefPubMed Turner J, Clark C (2016) Fluorescence imaging in anorectal advancement flaps. Dis Colon Rectum 59(7):700CrossRefPubMed
Metadaten
Titel
Early outcomes of fluorescence angiography in the setting of endorectal mucosa advancement flaps
verfasst von
J. S. Turner
A. Okonkwo
A. Chase
C. E. Clark
Publikationsdatum
18.12.2017
Verlag
Springer International Publishing
Erschienen in
Techniques in Coloproctology / Ausgabe 1/2018
Print ISSN: 1123-6337
Elektronische ISSN: 1128-045X
DOI
https://doi.org/10.1007/s10151-017-1732-7

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