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Japanese Journal of Ophthalmology

Erschienen in:

01.01.2012 | Clinical Investigation

Differential contributions of impaired corneal sensitivity and reduced tear secretion to corneal epithelial disorders

verfasst von: Teruo Nishida, Tai-Ichiro Chikama, Mitsuru Sawa, Kazunori Miyata, Takaaki Matsui, Kyoko Shigeta

Erschienen in: Japanese Journal of Ophthalmology | Ausgabe 1/2012

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Abstract

Background/aims

To determine the possible roles of impaired corneal sensitivity and reduced tear secretion in various types of corneal epithelial disorders.

Methods

A total of 99 patients (179 eyes) with corneal epithelial disorders classified as persistent epithelial defects (PED), corneal erosion, or superficial punctate keratopathy (SPK) and 115 individuals (230 eyes) without apparent ocular surface disorders (controls) were enrolled in a prospective study. Corneal sensitivity was measured with a Cochet-Bonnet esthesiometer, and tear secretion was measured by the Schirmer test in each subject.

Results

Corneal sensitivity of eyes in the PED and corneal erosion groups was significantly lower than that in the control group. Schirmer test values for eyes in the SPK group were significantly reduced compared with those in the control group.

Conclusion

A loss of corneal sensitivity may contribute to the development of PED and corneal erosion, whereas reduced tear secretion may be a contributing factor for SPK. Both results indicate the importance of corneal sensory innervation to the maintenance of corneal integrity.

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Titel: Differential contributions of impaired corneal sensitivity and reduced tear secretion to corneal epithelial disorders
verfasst von: Teruo Nishida
Tai-Ichiro Chikama
Mitsuru Sawa
Kazunori Miyata
Takaaki Matsui
Kyoko Shigeta
Publikationsdatum: 01.01.2012
Verlag: Springer Japan
Erschienen in: Japanese Journal of Ophthalmology / Ausgabe 1/2012
Print ISSN: 0021-5155
Elektronische ISSN: 1613-2246
DOI: https://doi.org/10.1007/s10384-011-0105-4

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Differential contributions of impaired corneal sensitivity and reduced tear secretion to corneal epithelial disorders

Abstract

Background/aims

Methods

Results

Conclusion

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Springer Medizin

Abstract

Background/aims

Methods

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