Preface 2010
Contents
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Figure 2 Survival of patients treated with EMR/ESD according to the pathological depth of tumor invasion (pT)×
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Figure 5 Survival of patients treated with definitive chemoradiotherapy according to clinical stage (UICC TNM 7th)×
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Figure 9 Survival of patients who underwent esophagectomy according to the depth of tumor invasion, pT (JES 10th)×
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Figure 10 Survival of patients who underwent esophagectomy according to lymph node metastasis, pN (JES 10th)×
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Figure 11 Survival of patients who underwent esophagectomy according to lymph node metastasis, pN (UICC 7th)×
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Figure 12 Survival of patients who underwent esophagectomy according to pathological stage (JES 10th)×
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Figure 13 Survival of patients who underwent esophagectomy according to pathological stage (UICC TNM 7th)×
I. Clinical factors of esophageal cancer patients treated in 2010
Institution-registered cases in 2010
Institution |
---|
Aichi Cancer Center |
Aichi Medical University Hospital |
Aizawa Hospital |
Akita Kouseiren Hiraka Hospital |
Akita University Hospital |
Arao Municipal Hospital |
Asahikawa Medical College Hospital |
Chiba Aoba Municipal Hospital |
Chiba Cancer Center |
Chiba Medical Center |
Chiba Prefectural Sawara Hospital |
Chiba University Hospital |
Chibaken Saiseikai Narashino Hospital |
Dokkyo Medical University Hospital |
Ehime University Hospital |
Foundation for Detection of Early Gastric Carcinoma |
Fuchu Hospital |
Fujioka General Hospital |
Fujisawa Shounandai Hospital |
Fujita Health University |
Fukui Prefectural Hospital |
Fukui University Hospital |
Fukuoka Dental College and Dental Hospital |
Fukuoka Saiseikai General Hospital |
Fukuoka University Chikushi Hospital |
Fukuoka University Hospital |
Fukuoka Wajiro Hospital |
Fukushima Medical University Hospital |
Fukuyama City Hospital |
Fussa Hospital |
Gifu Prefectural General Medical Center |
Gifu University Hospital |
Gunma Central General Hospital |
Gunma Prefectural Cancer Center |
Gunma University Hospital |
Gunmaken Saiseikai Maebashi Hospital |
Hachinohe City Hospital |
Hakodate Goryokaku Hospital |
Hakodate National Hospital |
Hamamatsu University School of Medicine, University Hospital |
Hannan Chuo Hospital |
Heartlife Hospital |
Higashiosaka City General Hospital |
Hiratsuka City Hospital |
Hiratsuka Kyosai Hospital |
Hirosaki University Hospital |
Hiroshima City Asa Hospital |
Hiroshima University Research Institute for Radiation Biology Medicine |
Hofu Institute of Gastroenterology |
Hokkaido Kin-Ikyo Chuo Hospital |
Hokkaido University Hospital |
Hyogo Cancer Center |
Hyogo College of Medicine |
Hyogo Prefectural Nishinomiya Hospital |
Ibaraki Prefectural Central Hospital |
Iizuka Hospital |
Ikeda Municipal Hospital |
Imazu Surgical Clinic |
Inazawa City Hospital |
International University of Health and Welfare Hospital |
International University of Health and Welfare, Mita Hospital |
Isehara Kyodo Hospital |
Ishikawa Prefectural Central Hospital |
Iwakuni Medical Center |
Iwate Medical University Hospital |
Iwate Prefectural Chubu Hospital |
Japanese Red Cross Fukui Hospital |
Japanese Red Cross Ishinomaki Hospital |
Japanese Red Cross Kyoto Daini Hospital? |
Japanese Red Cross Maebashi Hospital |
Japanese Red Cross Nagaoka Hospital |
Japanese Red Cross Okayama Hospital |
Japanese Red Cross Society Azumino Hospital |
Japanese Red Cross Tottori Hospital |
Jichi Medical University Hospital |
Juntendo University Hospital |
Juntendo University Shizuoka Hospital |
Junwakai Memorial Hospital |
Kagawa Prefectural Central Hospital |
Kagawa Rosai Hospital |
Kagawa University Hospital |
Kagoshima Kenritsu Satsunan Hospital |
Kagoshima University Hospital |
Kameda General Hospital |
Kanagawa Cancer Center |
Kanazawa Medical University Hospital |
Kanazawa University Hospital |
Kansai Medical University Hirakata Hospital |
Kansai Medical University Medical Center |
Kansai Rosai Hospital |
Kasamatsu Hospital |
Kashiwa Kousei General Hospital |
Kawakita General Hospital |
Kawasaki Medical School Hospital |
Kawasaki Medical School Kawasaki Hospital |
Kawasaki Municipal Ida Hospital |
Keio University Hospital |
Keiyukai Sapporo Hospital |
Kikuna Memorial Hospital |
Kinki Central Hospital |
Kinki University Hospital |
Kiryu Kosei General Hospital |
Kishiwada City Hospital |
Kitaakita Municipal Hospital |
Kitakyushu Municipal Medical Center |
Kitano Hospital |
Kobe City Medical Center General Hospital |
Kobe University Hospital |
Kochi Health Science Center |
Kochi University Hospital |
Kokura Memorial Hospital |
Kumamoto City Hospital |
Kumamoto University Hospital |
Kurashiki Central Hospital |
Kurume General Hospital |
Kurume University Hospital |
Kyoto University Hospital |
Kyushu Central Hospital of the Mutual Aid Association of Public School Teachers |
Kyushu Hospital |
Kyushu Medical Center |
Kyushu University Hospital |
Machida Municipal Hospital |
Matsuda Hospital |
Matsushita Memorial Hospital |
Matsuyama Red Cross Hospital |
Mie University Hospital |
Mino City Hospital |
Mito Red Cross Hospital |
Mitsui Memorial Hospital |
Miyazaki Konan Hospital |
Murakami General Hospital |
Musashino Red Cross Hospital |
Nagahama City Hospital |
Nagano Red Cross Hospital |
Nagaoka Chuo General Hospital |
Nagasaki University Hospital |
Nagayoshi General Hospital |
Nagoya City University Hospital |
Nagoya City West Medical Center |
Nagoya Daiichi Red Cross Hospital |
Nagoya University Hospital |
Nanpuh Hospital |
Nara Hospital Kinki University Faculty of Medicine |
Nara Medical University Hospital |
National Cancer Center Hospital |
National Cancer Center Hospital East |
National Defense Medical College Hospital |
National Hospital Organization Beppu Medical Center |
National Hospital Organization Chiba-East-Hospital |
National Hospital Organization Fukuoka-Higashi Medical Center |
National Hospital Organization Iwakuni Medical Center |
National Hospital Organization Kure Medical Center |
National Hospital Organization Kyoto Medical Center |
National Hospital Organization Kyushu Cancer Center |
National Hospital Organization Matsumoto National Hospital |
National Hospital Organization Nagasaki Medical Center |
National Hospital Organization Nagoya Medical Center |
National Hospital Organization Osaka National Hospital |
National Hospital Organization Tokyo Medical Center |
Niigata Cancer Center Hospital |
Niigata City General Hospital |
Niigata Prefectural Shibata Hospital |
Niigata University Medical and Dental Hospital |
Nikko Memorial Hospital |
Nippon Medical School Chiba Hokusoh Hospital |
Nippon Medical School Hospital |
Nippon Medical School Musashi Kosugi Hospital |
Nippon Medical School Tama Nagayama Hospital |
Nishi-Kobe Medical Center |
Nishinomiya Municipal Central Hospital |
Numazu City Hospital |
Obihiro Kousei General Hospital |
Obitsusankei Hospital |
Ohta General Hospital Foundation Ohta Nishinouchi Hospital |
Oita Red Cross Hospital |
Oita University Hospital |
Okayama Saiseikai General Hospital |
Okayama University Hospital |
Omuta City Hospital |
Osaka City University Hospital |
Osaka Hospital of Japan Seafarers Relief Association |
Osaka Medical Center for Cancer and Cardiovascular Diseases |
Osaka Medical College Hospital |
Osaka Police Hospital |
Osaka Prefectural Hospital Organization Osaka General Medical Center |
Osaka University Hospital |
Otsu Municipal Hospital |
Otsu Red Cross Hospital |
Rinku General Medical Center |
Ryukyu University Hospital |
Saga-ken Medical Center Koseikan |
Saiseikai Fukushima General Hospital |
Saiseikai Hiroshima Hospital |
Saiseikai Kyoto Hospital |
Saiseikai Yahata General Hospital |
Saitama Cancer Center |
Saitama City Hospital |
Saitama Medical Center |
Saitama Medical University Hospital |
Saitama Medical University Saitama International Medical Center |
Saitama Medical University Saitama Medical Center |
Sakai City Medical Center |
Saku Central Hospital |
Sanin Rosai Hospital |
Sano Kousei General Hospital |
Sendai City Hospital |
Sendai Medical Center |
Shiga Medical Center for Adults |
Shiga University of Medical Science Hospital |
Shikoku Cancer Center |
Shimada Hospital |
Shimane University Hospital |
Shimizu Welfare Hospital |
Shinshu University Hospital |
Shizuoka Cancer Center |
Shizuoka City Shizuoka Hospital |
Shizuoka General Hospital |
Showa University Fujigaoka Hospital |
Showa University Hospital |
Showa University Koto-Toyosu Hospital |
Showa University Northern Yokohama Hospital |
Social Insurance Omuta Tenryo Hospital |
Social Insurance Tagawa Hospital |
St. Marianna University School of Medical Hospital |
St. Luke’s International Hospital |
Sugita Genpaku Memorial Obama Municipal Hospital |
Suita Municipal Hospital |
Takasago Municipal Hospital |
Takatsuki Red Cross Hospital |
Takeda Hospital |
Teikyo University Hospital |
Teikyo University Hospital, Mizonokuchi |
Tenri Hospital |
The Cancer Institute Hospital of JFCR |
The Jikei University Hospital |
The Research Center Hospital for Charged Particle Therapy of NIRS |
Tochigi Medical Center |
Toho University Omori Medical Center |
Toho University Sakura Medical Center |
Tohoku Kosai Hospital |
Tohoku University Hospital |
Tokai University Hospital |
Tokushima Municipal Hospital |
Tokushima Prefectural Naruto Hospital |
Tokushima Red Cross Hospital |
Tokushima University Hospital |
Tokyo Dental College Ichikawa General Hospital |
Tokyo Medical and Dental University Hospital |
Tokyo Medical University Hospital |
Tokyo Medical University Ibaraki Medical Center |
Tokyo Metropolitan Health and Medical Corporation Toshima Hospital |
Tokyo University Hospital |
Tokyo Women’s Medical University Hospital |
Tokyo Women’s Medical University Medical Center East |
Tonan Hospital |
Toranomon Hospital |
Tottori Prefectural Central Hospital |
Tottori University Hospital |
Toyama Prefectural Central Hospital |
Toyama University Hospital |
Toyonaka Municipal Hospital |
Tsuchiura Kyodo Hospital |
Tsukuba University Hospital |
Tsuruoka Municipal Shonai Hospital |
University Hospital, Kyoto Prefectural University of Medicine |
University of Miyazaki Hospital |
Wakayama Medical University Hospital |
Yamagata Prefectural and Sakata Municipal Hospital Organization |
Yamagata Prefectural Central Hospital |
Yamagata Prefectural Shinjo Hospital |
Yamaguchi University Hospital |
Yamaguchi-ken Saiseikai Shimonoseki General Hospital |
Yamanashi Prefectural Central Hospital |
Yamanashi University Hospital |
Yao Municipal Hospital |
Yokohama Chuo Hospital |
Yokohama City Municipal Hospital |
Yokohama City University Hospital |
Yokohama City University Medical Center |
Yuri General Hospital |
Patient background
Age | Male | Female | Unknown | Cases (%) |
---|---|---|---|---|
≤29 | 1 | 1 | 2 (0.0%) | |
30–39 | 14 | 4 | 18 (0.3%) | |
40–49 | 125 | 44 | 169 (2.9%) | |
50–59 | 802 | 145 | 1 | 948 (16.1%) |
60–69 | 2140 | 291 | 1 | 2432 (41.4%) |
70–79 | 1596 | 267 | 1863 (31.7%) | |
80–89 | 342 | 78 | 420 (7.1%) | |
≥90 | 8 | 7 | 15 (0.3%) | |
Unknown | 10 | 1 | 11 (0.2%) | |
Total | 5038 | 838 | 2 | 5878 |
Treatments | Cases (%) |
---|---|
Surgery | 3638 (61.9%) |
Esophagectomy | 3564 (60.6%) |
Palliative | 74 (1.3%) |
Chemotherapy/radiotherapy | 1413 (24.0%) |
Endoscopic treatment | 827 (14.1%) |
Total | 5878 |
Location of tumor | Endoscopic treatment (%) | Surgery | Chemotherapy and/or radiotherapy (%) | Total (%) | |
---|---|---|---|---|---|
Esophagectomy (%) | Palliative surgery (%) | ||||
Cervical | 18 (2.2%) | 116 (3.3%) | 6 (8.1%) | 114 (8.1%) | 254 (4.3%) |
Upper thoracic | 90 (10.9%) | 411 (11.5%) | 15 (20.3%) | 233 (16.5%) | 749 (12.7%) |
Middle thoracic | 483 (58.4%) | 1669 (46.8%) | 39 (52.7%) | 677 (47.9%) | 2868 (48.8%) |
Lower thoracic | 186 (22.5%) | 1054 (29.6%) | 12 (16.2%) | 303 (21.4%) | 1555 (26.5%) |
EG | 34 (4.1%) | 241 (6.8%) | 1 (1.4%) | 31 (2.2%) | 307 (5.2%) |
E = G | 1 (0.1%) | 38 (1.1%) | 1 (1.4%) | 1 (0.1%) | 41 (0.7%) |
GE | 3 (0.4%) | 27 (0.8%) | 6 (0.4%) | 36 (0.6%) | |
Unknown | 12 (1.5%) | 8 (0.2%) | 48 (3.4%) | 68 (1.2%) | |
Total | 827 | 3564 | 74 | 1413 | 5878 |
Histologic types | Cases (%) |
---|---|
Squamous cell carcinoma | 5320 (90.5%) |
Squamous cell carcinoma | 3581 (60.9%) |
Well differentiated | 334 (5.7%) |
Moderately differentiated | 1072 (18.2%) |
Poorly differentiated | 333 (5.7%) |
Adenocarcinoma | 233 (4.0%) |
Barrett’s adenocarcinoma | 64 (1.1%) |
Adenosquamous carcinoma | 8 (0.1%) |
Mucoepidermoid carcinoma | 2 (0.0%) |
Basaloid carcinoma | 27 (0.5%) |
Endocrine cell carcinoma | 13 (0.2%) |
Undifferentiated carcinoma | 10 (0.2%) |
Sarcoma | 2 (0.0%) |
Malignant melanoma | 16 (0.3%) |
Carcinosarcoma | 9 (0.2%) |
GIST | 1 (0.0%) |
Other tumors | 34 (0.6%) |
Unknown | 139 (2.4%) |
Total | 5878 |
cT | Cases (%) |
---|---|
cTX | 16 (0.3%) |
cT0 | 9 (0.2%) |
cTis | 144 (2.4%) |
cT1a | 780 (13.3%) |
cT1b | 1130 (19.2%) |
cT2 | 813 (13.8%) |
cT3 | 2134 (36.3%) |
cT4a | 357 (6.1%) |
cT4b | 410 (7.0%) |
Unknown | 85 (1.4%) |
Total | 5878 |
cN | Cases (%) |
---|---|
cNX | 88 (1.5%) |
cN0 | 2646 (45.0%) |
cN1 | 1642 (27.9%) |
cN2 | 986 (16.8%) |
cN3 | 342 (5.8%) |
Unknown | 174 (3.0%) |
Total | 5878 |
cM | Cases (%) |
---|---|
cM0 | 5091 (86.6%) |
cM1 | 652 (11.1%) |
Unknown | 135 (2.3%) |
Total | 5878 |
Clinical stage | Endoscopic treatment (%) | Surgery | Chemotherapy and/or radiotherapy (%) | Total (%) | |
---|---|---|---|---|---|
Esophagectomy (%) | Palliative surgery (%) | ||||
0 | 112 (13.5%) | 12 (0.3%) | 1 (0.1%) | 125 (2.1%) | |
IA | 563 (68.1%) | 862 (24.2%) | 158 (11.2%) | 1583 (26.9%) | |
IB | 4 (0.5%) | 299 (8.4%) | 2 (2.7%) | 68 (4.8%) | 373 (6.3%) |
IIA | 2 (0.2%) | 336 (9.4%) | 7 (9.5%) | 49 (3.5%) | 394 (6.7%) |
IIB | 2 (0.2%) | 378 (10.6%) | 2 (2.7%) | 64 (4.5%) | 446 (7.6%) |
IIIA | 7 (0.8%) | 783 (22.0%) | 12 (16.2%) | 165 (11.7%) | 967 (16.5%) |
IIIB | 5 (0.6%) | 354 (9.9%) | 13 (17.6%) | 92 (6.5%) | 464 (7.9%) |
IIIC | 25 (3.0%) | 241 (6.8%) | 22 (29.7%) | 315 (22.3%) | 603 (10.3%) |
IV | 31 (3.7%) | 145 (4.1%) | 12 (16.2%) | 409 (28.9%) | 597 (10.2%) |
Unknown | 76 (9.2%) | 154 (4.3%) | 4 (5.4%) | 92 (6.5%) | 326 (5.5%) |
Total | 827 | 3564 | 74 | 1413 | 5878 |
II. Results of endoscopically treated patients in 2010
Treatment details | Cases (%) |
---|---|
EMR | 59 (7.8%) |
EMR + YAG laser | 6 (0.8%) |
ESD | 667 (88.5%) |
ESD + EMR | 6 (0.8%) |
ESD + PDT | 4 (0.5%) |
ESD + YAG laser | 1 (0.1%) |
PDT | 3 (0.4%) |
YAG laser | 8 (1.1%) |
Total | 754 |
Complications of EMR/ESD | Cases (%) |
---|---|
None | 672 (90.4%) |
Perforation | 13 (1.7%) |
Bleeding | 2 (0.3%) |
Mediastinitis | 4 (0.5%) |
Stenosis | 44 (5.9%) |
Others | 8 (1.1%) |
Total | 743 |
Pathological depth of tumor invasion (pT) | Cases (%) |
---|---|
pTX | 1 (0.1%) |
pT0 | 7 (0.9%) |
pTis | 163 (21.9%) |
pT1a | 482 (64.9%) |
pT1b | 74 (10.0%) |
pT2 | 1 (0.1%) |
Unknown | 15 (2.0%) |
Total | 743 |
III. Results in patients treated with chemotherapy and/or radiotherapy in 2010
Dose of irradiation (Gy) | Definitive | Palliative (%) | Recurrence (%) | Others (%) | Unknown (%) | Total (%) | |
---|---|---|---|---|---|---|---|
Radiation alone (%) | With chemotherapy (%) | ||||||
≤29 | 5 (2.9%) | 10 (1.4%) | 26 (9.2%) | 1 (2.7%) | 42 (3.5%) | ||
30–39 | 1 (0.6%) | 7 (1.0%) | 43 (15.1%) | 3 (10.0%) | 4 (10.8%) | 58 (4.8%) | |
40–49 | 9 (5.3%) | 24 (3.5%) | 36 (12.7%) | 1 (3.3%) | 10 (27.0%) | 80 (6.6%) | |
50–59 | 27 (15.9%) | 173 (25.0%) | 60 (21.1%) | 9 (30.0%) | 13 (35.1%) | 1 (33.3%) | 283 (23.3%) |
60–69 | 124 (72.9%) | 453 (65.5%) | 109 (38.4%) | 17 (56.7%) | 9 (24.3%) | 2 (66.7%) | 714 (58.7%) |
≥70 | 4 (7.2%) | 14 (2.1%) | 5 (0.0%) | 23 (2.2%) | |||
Unknown | 11 (1.6%) | 5 (1.8%) | 16 (1.3%) | ||||
Total | 170 | 692 | 284 | 30 | 37 | 3 | 1216 |
Median (min–max) | 60.0 (2.0–105.0) | 60.0 (1.8–72.0) | 52.5 (1.8–90.0) | 60.0 (37.5–67.0) | 50.0 (9.0–66.0) | 60.0 (52.0–60.0) | 60.0 (1.8–105.0) |
Dose of irradiation (Gy) | Preoperative irradiation (%) | Postoperative irradiation (%) |
---|---|---|
≤29 | 2 (1.0%) | |
30–39 | 34 (17.5%) | 1 (2.1%) |
40–49 | 132 (68.0%) | 10 (21.3%) |
50–59 | 7 (3.6%) | 12 (25.5%) |
60–69 | 13 (6.7%) | 22 (46.8%) |
≥70 | 2 (1.1%) | |
Unknown | 6 (3.1%) | |
Total | 194 | 47 |
Median (min–max) | 40.0 (0.0–66.0) | 60.0 (30.0–79.2) |
IV. Results in patients who underwent esophagectomy in 2010
Treatments | Cases (%) |
---|---|
Esophagectomy alone | 1463 (41.0%) |
Esophagectomy + endoscopic treatment | 83 (2.3%) |
Esophagectomy + chemoradiotherapy | 571 (16.0%) |
Concurrent chemoradiotherapy | 502 (14.1%) |
Other | 69 (1.9%) |
Esophagectomy + chemoradiotherapy + endoscopic treatment | 13 (0.4%) |
Esophagectomy + chemotherapy | 1391 (39.0%) |
Preoperative | 1027 (28.8%) |
Postoperative | 183 (5.1%) |
Pre and postoperative | 75 (2.1%) |
Recurrence | 46 (1.3%) |
Other | 60 (1.7%) |
Esophagectomy + chemotherapy + endoscopic treatment | 3 (0.1%) |
Esophagectomy + radiotherapy | 39 (1.1%) |
Preoperative | 4 (0.1%) |
Postoperative | 7 (0.2%) |
Recurrence | 15 (0.4%) |
Other | 13 (0.4%) |
Esophagectomy + radiotherapy + endoscopic treatment | 1 (0.0%) |
Total | 3564 |
Locations | Cases (%) |
---|---|
Cervical | 116 (3.3%) |
Upper thoracic | 411 (11.5%) |
Middle thoracic | 1669 (46.8%) |
Lower thoracic | 1054 (29.6%) |
E > G | 241 (6.8%) |
E = G | 38 (1.1%) |
G > E | 27 (0.8%) |
Unknown | 8 (0.2%) |
Total lesions | 3564 |
Approaches | Cases (%) |
---|---|
Cervical approach | 150 (4.2%) |
Right thoracotomy | 3010 (84.5%) |
Left thoracotomy | 50 (1.4%) |
Left thoracoabdominal approach | 58 (1.6%) |
Laparotomy | 108 (3.0%) |
Transhiatal thoracic esophagectomy | 50 (1.4%) |
Transhiatal lower esophagectomy | 72 (2.0%) |
Sternotomy | 4 (0.1%) |
Others | 28 (0.8%) |
Unknown | 34 (1.0%) |
Total | 3564 |
Video-assisted surgery | Cases (%) |
---|---|
None | 2117 (59.4%) |
Thoracoscopy | 653 (18.3%) |
Thoracoscopy + laparoscopy | 431 (12.1%) |
Thoracoscopy + laparoscopy + mediastinoscopy | 1 (0.0%) |
Thoracoscopy + laparoscopy + other | 1 (0.0%) |
Laparoscopy | 104 (2.9%) |
Laparoscopy + mediastinoscopy | 8 (0.2%) |
Laparoscopy + other | 1 (0.0%) |
Mediastinoscopy | 4 (0.1%) |
Others | 11 (0.3%) |
Total | 3564 |
Field of lymphadenectomy | Cervical | Upper thoracic | Middle thoracic | Lower thoracic | E > G | E = G | G > E | Unknown | Total |
---|---|---|---|---|---|---|---|---|---|
None | 10 (8.6%) | 13 (3.2%) | 59 (3.5%) | 28 (2.7%) | 13 (5.4%) | 2 (25.0%) | 125 (3.5%) | ||
C | 36 (31.0%) | 10 (2.4%) | 20 (1.2%) | 3 (0.3%) | 1 (0.4%) | 70 (2.0%) | |||
C + UM | 21 (18.1%) | 6 (1.5%) | 3 (0.2%) | 1 (0.1%) | 31 (0.9%) | ||||
C + UM + MLM | 2 (1.7%) | 12 (2.9%) | 28 (1.7%) | 12 (1.1%) | 1 (3.7%) | 55 (1.5%) | |||
C + UM + MLM + A | 27 (23.3%) | 257 (62.5%) | 800 (47.9%) | 367 (34.8%) | 26 (10.8%) | 6 (15.8%) | 1 (12.5%) | 1484 (41.6%) | |
C + UM + MLM + A+OT | 1 (0.1%) | 1 (0.0%) | |||||||
C + UM + A | 2 (1.7%) | 1 (0.2%) | 2 (0.1%) | 2 (0.2%) | 7 (0.2%) | ||||
C + MLM | 1 (0.1%) | 1 (0.0%) | |||||||
C + MLM + A | 3 (2.6%) | 1 (0.2%) | 7 (0.4%) | 3 (0.3%) | 14 (0.4%) | ||||
C + A | 1 (0.9%) | 2 (0.5%) | 4 (0.2%) | 2 (0.2%) | 1 (0.4%) | 10 (0.3%) | |||
UM | 4 (3.4%) | 3 (0.7%) | 5 (0.3%) | 3 (0.3%) | 15 (0.4%) | ||||
UM + MLM | 1 (0.9%) | 7 (1.7%) | 29 (1.7%) | 12 (1.1%) | 1 (0.4%) | 1 (12.5%) | 51 (1.4%) | ||
UM + MLM + A | 3 (2.6%) | 75 (18.2%) | 627 (37.6%) | 478 (45.4%) | 56 (23.2%) | 5 (13.2%) | 1 (3.7%) | 1 (12.5%) | 1246 (35.0%) |
UM + A | 1 (0.9%) | 4 (1.0%) | 2 (0.1%) | 2 (0.2%) | 2 (0.8%) | 11 (0.3%) | |||
MLM | 3 (0.7%) | 10 (0.6%) | 14 (1.3%) | 3 (1.2%) | 30 (0.8%) | ||||
MLM + A | 1 (0.9%) | 7 (1.7%) | 34 (2.0%) | 102 (9.7%) | 108 (44.8%) | 23 (60.5%) | 17 (63.0%) | 292 (8.2%) | |
A | 1 (0.9%) | 6 (1.5%) | 22 (1.3%) | 12 (1.1%) | 28 (11.6%) | 3 (7.9%) | 8 (29.6%) | 1 (12.5%) | 81 (2.3%) |
Unknown | 3 (2.6%) | 4 (1.0%) | 16 (1.0%) | 12 (1.1%) | 2 (0.8%) | 1 (2.6%) | 2 (25.0%) | 40 (1.1%) | |
Total | 116 | 411 | 1669 | 1054 | 241 | 38 | 27 | 8 | 3564 |
Reconstruction route | Cases (%) |
---|---|
None | 57 (1.6%) |
Subcutaneous | 302 (8.5%) |
Retrosternal | 1191 (33.4%) |
Posterior mediastinal | 1473 (41.3%) |
Intrathoracic | 435 (12.2%) |
Cervical | 50 (1.4%) |
Others | 34 (1.0%) |
Unknown | 22 (0.6%) |
Total | 3564 |
Organs used for reconstruction | Cases (%) |
---|---|
None | 72 (2.0%) |
Whole stomach | 71 (2.0%) |
Gastric tube | 3059 (85.0%) |
Jejunum | 176 (4.9%) |
Free jejunum | 69 (1.9%) |
Colon | 114 (3.2%) |
Free colon | 10 (0.3%) |
Others | 13 (0.4%) |
Unknown | 16 (0.4%) |
Total organs | 3600 |
Total cases | 3564 |
Histological classification | Cases (%) |
---|---|
Squamous cell carcinoma | 3045 (86.0%) |
Squamous cell carcinoma | 584 (16.5%) |
Well differentiated | 566 (16.0%) |
Moderately differentiated | 1445 (40.8%) |
Poorly differentiated | 450 (12.7%) |
Adenocarcinoma | 161 (4.5%) |
Barrett’s adenocarcinoma | 71 (2.0%) |
Adenosquamous cell carcinoma | 20 (0.6%) |
Mucoepidermoid carcinoma | 3 (0.1%) |
Adenoid cystic carcinoma | 2 (0.1%) |
Basaloid carcinoma | 71 (2.0%) |
Endocrine cell carcinoma | 15 (0.4%) |
Undifferentiated carcinoma | 6 (0.2%) |
Other carcinoma | 14 (0.4%) |
Carcinosarcoma | 18 (0.5%) |
Malignant melanoma | 16 (0.5%) |
GIST | 1 (0.0%) |
Other | 33 (0.9%) |
Unknown | 66 (1.9%) |
Total | 3542 |
pT category | Cases (%) |
---|---|
pTX | 25 (0.7%) |
pT0 | 79 (2.2%) |
pTis | 25 (0.7%) |
pT1a | 373 (10.5%) |
pT1b | 943 (26.5%) |
pT2 | 450 (12.6%) |
pT3 | 1368 (38.4%) |
pT4 | 111 (3.1%) |
pT4a | 34 (1.0%) |
pT4b | 33 (0.9%) |
Unknown | 123 (3.5%) |
Total | 3564 |
Lymph node metastasis | Cases (%) |
---|---|
pN0 | 2079 (58.3%) |
pN1 | 474 (13.3%) |
pN2 | 564 (15.8%) |
pN3 | 233 (6.5%) |
pN4 | 149 (4.2%) |
Unknown | 65 (1.8%) |
Total | 3564 |
Lymph node metastasis | Cases (%) |
---|---|
pN0 | 1571 (44.1%) |
pN1 (1–2) | 956 (26.8%) |
pN2 (3–6) | 623 (17.5%) |
pN3 (7–) | 351 (9.8%) |
Unknown | 63 (1.8%) |
Total | 3564 |
Distant metastasis | Cases (%) |
---|---|
pMX | 62 (1.7%) |
pM0 | 3446 (96.7%) |
pM1 | 56 (1.6%) |
Total | 3564 |
Residual tumor | Cases (%) |
---|---|
RX | 156 (4.1%) |
R0 | 3345 (87.0%) |
R1 | 187 (4.9%) |
R2 | 156 (4.1%) |
Total | 3844 |
Cause of death | Cases (%) |
---|---|
Death due to recurrence | 1139 (72.8%) |
Death due to other cancer | 65 (4.2%) |
Death due to other disease (rec+) | 44 (2.8%) |
Death due to other disease (rec−) | 179 (11.4%) |
Death due to other disease (rec?) | 7 (0.4%) |
Operative death* | 39 (2.5%) |
Postoperative hospital death** | 40 (2.6%) |
Unknown | 52 (3.3%) |
Total of death cases | 1565 (100%) |