Abstract
In the Western world, liver abscesses are predominantly of pyogenic origin and can present a wide range of ultrasonographic features, from a solid mass to a cystic cavity. Amoebic abscesses are endemic in tropical areas and typically round single lesions. Echinococcal cyst is diagnosed by ultrasound (US). Serology is particularly useful when pathognomonic US features are absent. Treatment is determined based on the WHO ultrasonographic classification, and puncture, aspiration, injection, re-aspiration (PAIR) is a US-guided therapeutic option. Hepatic alveolar echinococcosis presents on US as a pseudotumoral mass frequently with calcifications that may invade the biliary tree and portal and hepatic veins.
Similar content being viewed by others
References
Rahimian J, Wilson T, Oram V, et al. Pyogenic liver abscess: recent trends in etiology and mortality. Clin Infect Dis. 2004;39:1654–9.
Nunnari G, Pinzone MR, Gruttadauria S, et al. Hepatic echinococcosis: clinical and therapeutic aspects. World J Gastroenterol. 2012;18:1448–58.
Brunetti E, Kern P, Vuitton DA. WHO-IWGE WPft. Expert consensus for the diagnosis and treatment of cystic and alveolar echinococcosis in humans. Acta Trop. 2010;114:1–16.
Krige JE, Beckingham IJ. ABC of diseases of liver, pancreas, and biliary system. BMJ. 2001;322:537–40.
Othman N, Mohamed Z, Yahya MM, et al. Entamoeba histolytica antigenic protein detected in pus aspirates from patients with amoebic liver abscess. Exp Parasitol. 2003;134:504–10.
Eckert J, Schantz P, Gasser R. Geographic distribution and prevalence. In: Eckert J GM, Meslin FX, Pawlowski ZS (eds.), Paris; 2001.
Vassiliades VG, Bree RL, Korobkin M. Focal and diffuse benign hepatic disease: correlative imaging. Semin Ultrasound CT MR. 1992;13:313–35.
Allan PL, Baxter GM, Weston MJ. Clinical Ultrasound. Third ed. Churchill Livingstone, Elsevier; 2011. p. 124–127.
Claudon M, Dietrich CF, Choi BI, Cosgrove DO, Kudo M, Nolsøe CP, Piscaglia F, Wilson SR, Barr RG, Chammas MC, Chaubal NG, Chen MH, Clevert DA, Correas JM, Ding H, Forsberg F, Fowlkes JB, Gibson RN, Goldberg BB, Lassau N, Leen EL, Mattrey RF, Moriyasu F, Solbiati L, Weskott HP, Xu HX. World Federation for Ultrasound in Medicine, European Federation of Societies for Ultrasound. Guidelines and good clinical practice recommendations for Contrast Enhanced Ultrasound (CEUS) in the liver–update 2012: A WFUMB-EFSUMB initiative in cooperation with representatives of AFSUMB, AIUM, ASUM, FLAUS and ICUS. Ultrasound Med Biol. 2013;39(2):187–210. doi:10.1016/j.ultrasmedbio.2012.09.002.
Branum GD, Tyson GS, Branum MA, et al. Hepatic abscess. Changes in etiology, diagnosis, and management. Ann Surg. 1990;212:655–62.
Shibata T, Yamamoto Y, Yamamoto N, et al. Cholangitis and liver abscess after percutaneous ablation therapy for liver tumors: incidence and risk factors. J Vasc Interv Radiol. 2001;14:1535–42.
Lederman ER, Crum NF. Pyogenic liver abscess with a focus on Klebsiella pneumoniae as a primary pathogen: an emerging disease with unique clinical characteristics. Am J Gastroenterol. 2005;100:322–31.
Terrier F, Becker CD, Triller JK. Morphologic aspects of hepatic abscesses at computed tomography and ultrasound. Acta Radiol Diagn (Stockh). 1983;24:129–37.
Bates J. Abdominal Ultrasound. How, Why and When. In: Churchil Livingstone E, editor. Second ed. 2004; p. 82–84.
Seitz K, Strobel D, Bernatik T, et al. Contrast-Enhanced Ultrasound (CEUS) for the characterization of focal liver lesions–prospective comparison in clinical practice: CEUS vs. CT (DEGUM multicenter trial). Ultraschall Med. 2008;30:383–9.
Kachare MB, Desai NS, Patki VK, et al. Gas-forming liver abscess in a patient with multi-organ failure: role of imaging and management. Acta Clin Belg. 2014;69:226–8.
Kishina M, Koda M, Tokunaga S, et al. Usefulness of contrast-enhanced ultrasound with Sonazoid for evaluating liver abscess in comparison with conventional B-mode ultrasound. Hepatol Res. 2015;45:337–42.
Liu GJ, Lu MD, Xie XY, et al. Real-time contrast-enhanced ultrasound imaging of infected focal liver lesions. J Ultrasound Med. 2008;27:657–66.
Heneghan HM, Healy NA, Martin ST, et al. Modern management of pyogenic hepatic abscess: a case series and review of the literature. BMC Res Notes. 2001;4:80.
Dietrich CF, Lorentzen T, Appelbaum L. EFSUMB Guidelines on Interventional Ultrasound (INVUS), Part III Abdominal Treatment Procedures. Ultraschall Med. 2016;37:1–32.
Giorgio A, de Stefano G, Di Sarno A, et al. Percutaneous needle aspiration of multiple pyogenic abscesses of the liver: 13-year single-center experience. AJR Am J Roentgenol. 2006;187:1585–90.
Zerem E, Omerovic S, Kunosic S. Sonographically guided percutaneous treatment of liver abscesses in critically Ill patients. J Clin Ultrasound. 2014;42:527–33.
Singh O, Gupta S, Moses S, et al. Comparative study of catheter drainage and needle aspiration in management of large liver abscesses. Indian J Gastroenterol. 2009;28:88–92.
Cai YL, Xiong XZ, Lu J, et al. Percutaneous needle aspiration versus catheter drainage in the management of liver abscess: a systematic review and meta-analysis. HPB. 2015;17:195–201.
K CS, Sharma D. Long-term follow-up of pyogenic liver abscess by ultrasound. Eur J Radiol. 2010;74:195–8.
Haque R, Huston CD, Hughes M, et al. Amebiasis. N Engl J Med. 2003;348:1565–73.
Lutz HT, Gharbi HA. Manual of diagnostic ultrasound in infectious tropical diseases. Germany: Springer; 2006. p. 93–102.
Salles JM, Moraes LA, Salles MC. Hepatic amebiasis. Braz J Infect Dis. 2003;7:96–110.
Debnath MR, Debnath CR, Rahman SI, et al. Ultrasonographic evaluation of morphologic pattern of amoebic liver abscess. Mymensingh Med J. 2002;21:583–7.
Benedetti NJ, Desser TS, Jeffrey RB. Imaging of hepatic infections. Ultrasound Q. 2008;24:267–78.
Barnes PF, De Cock KM, Reynolds TN, et al. A comparison of amebic and pyogenic abscess of the liver. Medicine. 1987;66:472–83.
Salles JM, Salles MJ, Moraes LA, et al. Invasive amebiasis: an update on diagnosis and management. Expert Rev Anti Infect Ther. 2007;5:893–901.
Chavez-Tapia NC, Hernandez-Calleros J, Tellez-Avila FI, et al. Image-guided percutaneous procedure plus metronidazole versus metronidazole alone for uncomplicated amoebic liver abscess. Cochrane Database Syst Rev. 2009; CD004886.
Berry M, Bazaz R, Bhargava S. Amebic liver abscess: sonographic diagnosis and management. J Clin Ultrasound. 1986;14:239–42.
Sharma MP, Dasarathy S, Sushma S, et al. Long term follow-up of amebic liver abscess: clinical and ultrasound patterns of resolution. Trop Gastroenterol. 1995;16:24–8.
Pedrosa I, Saíz A, Arrazola J, et al. Hydatid disease: radiologic and pathologic features and complications. Radiographics. 2000;20:795–817.
Atli M, Kama NA, Yuksek YN, et al. Intrabiliary rupture of a hepatic hydatid cyst: associated clinical factors and proper management. Arch Surg. 2001;136:1249–55.
Group WIW. International classification of ultrasound images in cystic echinococcosis for application in clinical and field epidemiological settings. Acta Trop. 2003;85:253–61.
Gargouri M, Ben Amor N, Ben Chehida F, et al. Percutaneous treatment of hydatid cysts (Echinococcus granulosus). Cardiovasc Intervent Radiol. 1990;13:169–73.
Ustünsöz B, Akhan O, Kamiloğlu MA, et al. Percutaneous treatment of hydatid cysts of the liver: long-term results. AJR Am J Roentgenol. 1999;172:91–6.
Giorgio A, Di Sarno A, de Stefano G, et al. Sonography and clinical outcome of viable hydatid liver cysts treated with double percutaneous aspiration and ethanol injection as first-line therapy: efficacy and long-term follow-up. AJR Am J Roentgenol. 2009;193:186–92.
Massolo A, Liccioli S, Budke C, et al. Echinococcus multilocularis in North America: the great unknown. Parasite. 2014; p. 21–73.
Czermak BV, Unsinn KM, Gotwald T, et al. Echinococcus multilocularis revisited. AJR Am J Roentgenol. 2001;176:1207–12.
Claudon M, Bessieres M, Regent D, et al. Alveolar echinococcosis of the liver: MR findings. J Comput Assist Tomogr. 1990;14:608–14.
Bresson-Hadni S, Delabrousse E, Blagosklonov O, et al. Imaging aspects and non-surgical interventional treatment in human alveolar echinococcosis. Parasitol Int. 2006;55:267–72.
Kaltenbach TE, Graeter T, Mason RA, et al. Determination of vitality of liver lesions by alveolar echinococcosis. Comparison of parametric contrast enhanced ultrasound (SonoVue®) with quantified 18F-FDG-PET-CT. Nuklearmedizin. 2015;54:43–9.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Ethical statements
This article does not contain any studies with human participants performed by any of the authors. Informed consent was obtained from all individual participants included in the study.
Conflict of interest
Rita Barosa, João Pinto, Ana Caldeira, and Eduardo Pereira declare that they have no conflict of interest.
About this article
Cite this article
Barosa, R., Pinto, J., Caldeira, A. et al. Modern role of clinical ultrasound in liver abscess and echinococcosis. J Med Ultrasonics 44, 239–245 (2017). https://doi.org/10.1007/s10396-016-0765-2
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10396-016-0765-2