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AIDS and Behavior

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01.05.2006 | Original Article

Self-Report Measures of Antiretroviral Therapy Adherence: A Review with Recommendations for HIV Research and Clinical Management

verfasst von: Jane M. Simoni, Ann E. Kurth, Cynthia R. Pearson, David W. Pantalone, Joseph O. Merrill, Pamela A. Frick

Erschienen in: AIDS and Behavior | Ausgabe 3/2006

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Abstract

A review of 77 studies employing self-report measures of antiretroviral adherence published 1/1996 through 8/2004 revealed great variety in adherence assessment item content, format, and response options. Recall periods ranged from 2 to 365 days (mode=7 days). The most common cutoff for optimal adherence was 100% (21/48 studies, or 44%). In 27 of 34 recall periods (79%), self-reported adherence was associated with adherence as assessed with other indirect measures. Data from 57 of 67 recall periods (84%) indicated self-reported adherence was significantly associated with HIV-1 RNA viral load; in 16 of 26 (62%), it was associated with CD4 count. Clearly, the field would benefit from item standardization and a priori definitions and operationalizations of adherence. We conclude that even brief self-report measures of antiretroviral adherence can be robust, and recommend items and strategies for HIV research and clinical management.

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Titel: Self-Report Measures of Antiretroviral Therapy Adherence: A Review with Recommendations for HIV Research and Clinical Management
verfasst von: Jane M. Simoni
Ann E. Kurth
Cynthia R. Pearson
David W. Pantalone
Joseph O. Merrill
Pamela A. Frick
Publikationsdatum: 01.05.2006
Verlag: Springer US
Erschienen in: AIDS and Behavior / Ausgabe 3/2006
Print ISSN: 1090-7165
Elektronische ISSN: 1573-3254
DOI: https://doi.org/10.1007/s10461-006-9078-6

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Self-Report Measures of Antiretroviral Therapy Adherence: A Review with Recommendations for HIV Research and Clinical Management

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