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Erschienen in: AIDS and Behavior 6/2010

01.12.2010 | Review Paper

Neurocognitive Impairment and HIV Risk Factors: A Reciprocal Relationship

verfasst von: Pria Anand, Sandra A. Springer, Michael M. Copenhaver, Frederick L. Altice

Erschienen in: AIDS and Behavior | Ausgabe 6/2010

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Abstract

Cognitive impairment among populations at risk for HIV poses a significant barrier to managing risk behaviors. The impact of HIV and several cofactors, including substance abuse and mental illness, on cognitive function is discussed in the context of HIV risk behaviors, medication adherence, and risk-reduction interventions. Literature suggests that cognitive impairment is intertwined in a close, reciprocal relationship with both risk behaviors and medication adherence. Not only do increased risk behaviors and suboptimal adherence exacerbate cognitive impairment, but cognitive impairment also reduces the effectiveness of interventions aimed at optimizing medication adherence and reducing risk. In order to be effective, risk-reduction interventions must therefore take into account the impact of cognitive impairment on learning and behavior.
Literatur
1.
Zurück zum Zitat World Health Organization. Report on the global AIDS epidemic. Geneva, Switzerland; 2008. World Health Organization. Report on the global AIDS epidemic. Geneva, Switzerland; 2008.
2.
Zurück zum Zitat Norman LR, Basso M, Kumar A, Malow R. Neuropsychological consequences of HIV and substance abuse: a literature review and implications for treatment and future research. Curr Drug Abuse Rev. 2009;2(2):143–56.CrossRefPubMed Norman LR, Basso M, Kumar A, Malow R. Neuropsychological consequences of HIV and substance abuse: a literature review and implications for treatment and future research. Curr Drug Abuse Rev. 2009;2(2):143–56.CrossRefPubMed
3.
Zurück zum Zitat Woods SP, Moore DJ, Weber E, Grant I. Cognitive neuropsychology of HIV-associated neurocognitive disorders. Neuropsychol Rev. 2009;19(2):152–68.CrossRefPubMed Woods SP, Moore DJ, Weber E, Grant I. Cognitive neuropsychology of HIV-associated neurocognitive disorders. Neuropsychol Rev. 2009;19(2):152–68.CrossRefPubMed
4.
Zurück zum Zitat Cysique LA, Brew BJ. Neuropsychological functioning and antiretroviral treatment in HIV/AIDS: a review. Neuropsychol Rev. 2009;19(2):169–85.CrossRefPubMed Cysique LA, Brew BJ. Neuropsychological functioning and antiretroviral treatment in HIV/AIDS: a review. Neuropsychol Rev. 2009;19(2):169–85.CrossRefPubMed
5.
Zurück zum Zitat Lovejoy TI, Suhr JA. The relationship between neuropsychological functioning and HAART adherence in HIV-positive adults: a systematic review. J Behav Med. 2009;32(5):389–405.CrossRefPubMed Lovejoy TI, Suhr JA. The relationship between neuropsychological functioning and HAART adherence in HIV-positive adults: a systematic review. J Behav Med. 2009;32(5):389–405.CrossRefPubMed
6.
Zurück zum Zitat Gray F, Adle-Biassette H, Chretien F, et al. Neuropathology and neurodegeneration in human immunodeficiency virus infection. Pathogenesis of HIV-induced lesions of the brain, correlations with HIV-associated disorders and modifications according to treatments. Clin Neuropathol. 2001;20(4):146–55.PubMed Gray F, Adle-Biassette H, Chretien F, et al. Neuropathology and neurodegeneration in human immunodeficiency virus infection. Pathogenesis of HIV-induced lesions of the brain, correlations with HIV-associated disorders and modifications according to treatments. Clin Neuropathol. 2001;20(4):146–55.PubMed
7.
8.
Zurück zum Zitat Reger M, Welsh R, Razani J, Martin DJ, Boone KB. A meta-analysis of the neuropsychological sequelae of HIV infection. J Int Neuropsychol Soc. 2002;8(3):410–24.CrossRefPubMed Reger M, Welsh R, Razani J, Martin DJ, Boone KB. A meta-analysis of the neuropsychological sequelae of HIV infection. J Int Neuropsychol Soc. 2002;8(3):410–24.CrossRefPubMed
9.
Zurück zum Zitat Cysique LA, Maruff P, Brew BJ. Variable benefit in neuropsychological function in HIV-infected HAART-treated patients. Neurology. 2006;66(9):1447–50.CrossRefPubMed Cysique LA, Maruff P, Brew BJ. Variable benefit in neuropsychological function in HIV-infected HAART-treated patients. Neurology. 2006;66(9):1447–50.CrossRefPubMed
10.
Zurück zum Zitat Applebaum AJ, Otto MW, Richardson MA, Safren SA. Contributors to neuropsychological impairment in HIV-infected and HIV-uninfected opiate-dependent patients. J Clin Exp Neuropsychol. 2009:1–11. Applebaum AJ, Otto MW, Richardson MA, Safren SA. Contributors to neuropsychological impairment in HIV-infected and HIV-uninfected opiate-dependent patients. J Clin Exp Neuropsychol. 2009:1–11.
11.
Zurück zum Zitat Li W, Galey D, Mattson MP, Nath A. Molecular and cellular mechanisms of neuronal cell death in HIV dementia. Neurotox Res. 2005;8(1–2):119–34.CrossRefPubMed Li W, Galey D, Mattson MP, Nath A. Molecular and cellular mechanisms of neuronal cell death in HIV dementia. Neurotox Res. 2005;8(1–2):119–34.CrossRefPubMed
12.
Zurück zum Zitat Lopez OL, Smith G, Meltzer CC, Becker JT. Dopamine systems in human immunodeficiency virus-associated dementia. Neuropsychiatry Neuropsychol Behav Neurol. 1999;12(3):184–92.PubMed Lopez OL, Smith G, Meltzer CC, Becker JT. Dopamine systems in human immunodeficiency virus-associated dementia. Neuropsychiatry Neuropsychol Behav Neurol. 1999;12(3):184–92.PubMed
13.
Zurück zum Zitat Mayer K, Pizer H. HIV prevention: a comprehensive approach. London: Academic Press; 2008. Mayer K, Pizer H. HIV prevention: a comprehensive approach. London: Academic Press; 2008.
14.
Zurück zum Zitat Lucas GM, Cheever LW, Chaisson RE, Moore RD. Detrimental effects of continued illicit drug use on the treatment of HIV-1 infection. J Acquir Immune Defic Syndr. 2001;27(3):251–9.PubMed Lucas GM, Cheever LW, Chaisson RE, Moore RD. Detrimental effects of continued illicit drug use on the treatment of HIV-1 infection. J Acquir Immune Defic Syndr. 2001;27(3):251–9.PubMed
15.
Zurück zum Zitat Rapeli P, Kivisaari R, Autti T, et al. Cognitive function during early abstinence from opioid dependence: a comparison to age, gender, and verbal intelligence matched controls. BMC Psychiatry. 2006;6:9. Rapeli P, Kivisaari R, Autti T, et al. Cognitive function during early abstinence from opioid dependence: a comparison to age, gender, and verbal intelligence matched controls. BMC Psychiatry. 2006;6:9.
16.
Zurück zum Zitat Verdejo-Garcia A, Lopez-Torrecillas F, Gimenez CO, Perez-Garcia M. Clinical implications and methodological challenges in the study of the neuropsychological correlates of cannabis, stimulant, and opioid abuse. Neuropsychol Rev. 2004;14(1):1–41.CrossRefPubMed Verdejo-Garcia A, Lopez-Torrecillas F, Gimenez CO, Perez-Garcia M. Clinical implications and methodological challenges in the study of the neuropsychological correlates of cannabis, stimulant, and opioid abuse. Neuropsychol Rev. 2004;14(1):1–41.CrossRefPubMed
17.
Zurück zum Zitat Di Franco MJ, Marlink R, Hunter DJ, et al. Association of immune activation with intravenous heroin use and methadone treatment in HIV-1 seropositive and seronegative subjects. J Acquir Immune Defic Syndr. 1993;6(12):1297–300.PubMed Di Franco MJ, Marlink R, Hunter DJ, et al. Association of immune activation with intravenous heroin use and methadone treatment in HIV-1 seropositive and seronegative subjects. J Acquir Immune Defic Syndr. 1993;6(12):1297–300.PubMed
18.
Zurück zum Zitat Margolin A, Avants SK, Warburton LA, Hawkins KA. Factors affecting cognitive functioning in a sample of human immunodeficiency virus-positive injection drug users. AIDS Patient Care STDS. 2002;16(6):255–67.CrossRefPubMed Margolin A, Avants SK, Warburton LA, Hawkins KA. Factors affecting cognitive functioning in a sample of human immunodeficiency virus-positive injection drug users. AIDS Patient Care STDS. 2002;16(6):255–67.CrossRefPubMed
19.
Zurück zum Zitat Copenhaver M, Avants SK, Warburton LA, Margolin A. Intervening effectively with drug abusers infected with HIV: taking into account the potential for cognitive impairment. J Psychoactive Drugs. 2003;35(2):209–18.PubMed Copenhaver M, Avants SK, Warburton LA, Margolin A. Intervening effectively with drug abusers infected with HIV: taking into account the potential for cognitive impairment. J Psychoactive Drugs. 2003;35(2):209–18.PubMed
20.
Zurück zum Zitat Zhang L, Looney D, Taub D, et al. Cocaine opens the blood-brain barrier to HIV-1 invasion. J Neurovirol. 1998;4(6):619–26.CrossRefPubMed Zhang L, Looney D, Taub D, et al. Cocaine opens the blood-brain barrier to HIV-1 invasion. J Neurovirol. 1998;4(6):619–26.CrossRefPubMed
21.
Zurück zum Zitat Bruce RD, Altice FL. Clinical care of the HIV-infected drug user. Infect Dis Clin North Am. 2007;21(1):149–79.CrossRefPubMed Bruce RD, Altice FL. Clinical care of the HIV-infected drug user. Infect Dis Clin North Am. 2007;21(1):149–79.CrossRefPubMed
22.
Zurück zum Zitat McCann UD, Wong DF, Yokoi F, et al. Reduced striatal dopamine transporter density in abstinent methamphetamine and methcathinone users: evidence from positron emission tomography studies with [11C]WIN-35, 428. J Neurosci. 1998;18(20):8417–22.PubMed McCann UD, Wong DF, Yokoi F, et al. Reduced striatal dopamine transporter density in abstinent methamphetamine and methcathinone users: evidence from positron emission tomography studies with [11C]WIN-35, 428. J Neurosci. 1998;18(20):8417–22.PubMed
23.
Zurück zum Zitat Jernigan TL, Gamst AC, Archibald SL, et al. Effects of methamphetamine dependence and HIV infection on cerebral morphology. Am J Psychiatry. 2005;162(8):1461–72.CrossRefPubMed Jernigan TL, Gamst AC, Archibald SL, et al. Effects of methamphetamine dependence and HIV infection on cerebral morphology. Am J Psychiatry. 2005;162(8):1461–72.CrossRefPubMed
24.
Zurück zum Zitat Simon SL, Domier C, Carnell J, et al. Cognitive impairment in individuals currently using methamphetamine. Am J Addict. 2000;9(3):222–31.CrossRefPubMed Simon SL, Domier C, Carnell J, et al. Cognitive impairment in individuals currently using methamphetamine. Am J Addict. 2000;9(3):222–31.CrossRefPubMed
25.
Zurück zum Zitat Coffey SF, Gudleski GD, Saladin ME, Brady KT. Impulsivity and rapid discounting of delayed hypothetical rewards in cocaine-dependent individuals. Exp Clin Psychopharmacol. 2003;11(1):18–25.CrossRefPubMed Coffey SF, Gudleski GD, Saladin ME, Brady KT. Impulsivity and rapid discounting of delayed hypothetical rewards in cocaine-dependent individuals. Exp Clin Psychopharmacol. 2003;11(1):18–25.CrossRefPubMed
26.
Zurück zum Zitat Nordahl TE, Salo R, Leamon M. Neuropsychological effects of chronic methamphetamine use on neurotransmitters and cognition: a review. J Neuropsychiatry Clin Neurosci. 2003;15(3):317–25.PubMed Nordahl TE, Salo R, Leamon M. Neuropsychological effects of chronic methamphetamine use on neurotransmitters and cognition: a review. J Neuropsychiatry Clin Neurosci. 2003;15(3):317–25.PubMed
27.
Zurück zum Zitat Simon SL, Domier CP, Sim T, et al. Cognitive performance of current methamphetamine and cocaine abusers. J Addict Dis. 2002;21(1):61–74.CrossRefPubMed Simon SL, Domier CP, Sim T, et al. Cognitive performance of current methamphetamine and cocaine abusers. J Addict Dis. 2002;21(1):61–74.CrossRefPubMed
28.
Zurück zum Zitat Wilson J, Kalasinsky K, Levey A, et al. Striatal dopamine nerve terminal markers in human, chronic methamphetamine users. Nat Med. 1996;2(6):699–703.CrossRefPubMed Wilson J, Kalasinsky K, Levey A, et al. Striatal dopamine nerve terminal markers in human, chronic methamphetamine users. Nat Med. 1996;2(6):699–703.CrossRefPubMed
29.
Zurück zum Zitat Lundh H, Tunving K. An extrapyramidal choreiform syndrome caused by amphetamine addiction. J Neurol Neurosurg Psychiatry. 1981;44(8):728–30.CrossRefPubMed Lundh H, Tunving K. An extrapyramidal choreiform syndrome caused by amphetamine addiction. J Neurol Neurosurg Psychiatry. 1981;44(8):728–30.CrossRefPubMed
30.
Zurück zum Zitat Garwood ER, Bekele W, McCulloch CE, Christine CW. Amphetamine exposure is elevated in Parkinson’s disease. Neurotoxicology. 2006;27(6):1003–6.CrossRefPubMed Garwood ER, Bekele W, McCulloch CE, Christine CW. Amphetamine exposure is elevated in Parkinson’s disease. Neurotoxicology. 2006;27(6):1003–6.CrossRefPubMed
31.
Zurück zum Zitat Moszczynska A, Fitzmaurice P, Ang L, et al. Why is parkinsonism not a feature of human methamphetamine users? Brain. 2004;127(2):363–70.CrossRefPubMed Moszczynska A, Fitzmaurice P, Ang L, et al. Why is parkinsonism not a feature of human methamphetamine users? Brain. 2004;127(2):363–70.CrossRefPubMed
32.
Zurück zum Zitat Darke S, Sims J, McDonald S, Wickes W. Cognitive impairment among methadone maintenance patients. Addiction. 2000;95(5):687–95.CrossRefPubMed Darke S, Sims J, McDonald S, Wickes W. Cognitive impairment among methadone maintenance patients. Addiction. 2000;95(5):687–95.CrossRefPubMed
33.
Zurück zum Zitat Brandt J, Butters N, Ryan C, Bayog R. Cognitive loss and recovery in long-term alcohol abusers. Arch Gen Psychiatry. 1983;40(4):435–42.PubMed Brandt J, Butters N, Ryan C, Bayog R. Cognitive loss and recovery in long-term alcohol abusers. Arch Gen Psychiatry. 1983;40(4):435–42.PubMed
34.
Zurück zum Zitat Green JE, Saveanu RV, Bornstein RA. The effect of previous alcohol abuse on cognitive function in HIV infection. Am J Psychiatry. 2004;161(2):249–54.CrossRefPubMed Green JE, Saveanu RV, Bornstein RA. The effect of previous alcohol abuse on cognitive function in HIV infection. Am J Psychiatry. 2004;161(2):249–54.CrossRefPubMed
35.
Zurück zum Zitat Cook CC, Hallwood PM, Thomson AD. B Vitamin deficiency and neuropsychiatric syndromes in alcohol misuse. Alcohol Alcohol. 1998;33(4):317–36.PubMed Cook CC, Hallwood PM, Thomson AD. B Vitamin deficiency and neuropsychiatric syndromes in alcohol misuse. Alcohol Alcohol. 1998;33(4):317–36.PubMed
36.
Zurück zum Zitat Verdejo A, Toribio I, Orozco C, Puente KL, Perez-Garcia M. Neuropsychological functioning in methadone maintenance patients versus abstinent heroin abusers. Drug Alcohol Depend. 2005;78(3):283–8.CrossRefPubMed Verdejo A, Toribio I, Orozco C, Puente KL, Perez-Garcia M. Neuropsychological functioning in methadone maintenance patients versus abstinent heroin abusers. Drug Alcohol Depend. 2005;78(3):283–8.CrossRefPubMed
37.
Zurück zum Zitat Rapeli P, Fabritius C, Alho H, et al. Methadone vs. buprenorphine/naloxone during early opioid substitution treatment: a naturalistic comparison of cognitive performance relative to healthy controls. BMC Clin Pharmacol. 2007;7:5.CrossRefPubMed Rapeli P, Fabritius C, Alho H, et al. Methadone vs. buprenorphine/naloxone during early opioid substitution treatment: a naturalistic comparison of cognitive performance relative to healthy controls. BMC Clin Pharmacol. 2007;7:5.CrossRefPubMed
38.
Zurück zum Zitat Bica I, McGovern B, Dhar R, et al. Increasing mortality due to end-stage liver disease in patients with human immunodeficiency virus infection. Clin Infect Dis. 2001;32(3):492–7.CrossRefPubMed Bica I, McGovern B, Dhar R, et al. Increasing mortality due to end-stage liver disease in patients with human immunodeficiency virus infection. Clin Infect Dis. 2001;32(3):492–7.CrossRefPubMed
39.
Zurück zum Zitat Cherner M, Letendre S, Heaton RK, et al. Hepatitis C augments cognitive deficits associated with HIV infection and methamphetamine. Neurology. 2005;64(8):1343–7.PubMed Cherner M, Letendre S, Heaton RK, et al. Hepatitis C augments cognitive deficits associated with HIV infection and methamphetamine. Neurology. 2005;64(8):1343–7.PubMed
40.
Zurück zum Zitat Cournos F, McKinnon K, Wainberg M. What can mental health interventions contribute to the global struggle against HIV/AIDS? World Psychiatry. 2005;4(3):135–41.PubMed Cournos F, McKinnon K, Wainberg M. What can mental health interventions contribute to the global struggle against HIV/AIDS? World Psychiatry. 2005;4(3):135–41.PubMed
41.
Zurück zum Zitat Jaffe MP, O’Neill J, Vandergoot D, Gordon WA, Small B. The unveiling of traumatic brain injury in an HIV/AIDS population. Brain Inj. 2000;14(1):35–44.CrossRefPubMed Jaffe MP, O’Neill J, Vandergoot D, Gordon WA, Small B. The unveiling of traumatic brain injury in an HIV/AIDS population. Brain Inj. 2000;14(1):35–44.CrossRefPubMed
42.
Zurück zum Zitat Meade CS, Sikkema KJ. HIV risk behavior among adults with severe mental illness: a systematic review. Clin Psychol Rev. 2005;25(4):433–57.CrossRefPubMed Meade CS, Sikkema KJ. HIV risk behavior among adults with severe mental illness: a systematic review. Clin Psychol Rev. 2005;25(4):433–57.CrossRefPubMed
43.
Zurück zum Zitat Weinhardt LS, Carey MP, Carey KB, Maisto SA, Gordon CM. The relation of alcohol use to HIV-risk sexual behavior among adults with a severe and persistent mental illness. J Consult Clin Psychol. 2001;69(1):77–84.CrossRefPubMed Weinhardt LS, Carey MP, Carey KB, Maisto SA, Gordon CM. The relation of alcohol use to HIV-risk sexual behavior among adults with a severe and persistent mental illness. J Consult Clin Psychol. 2001;69(1):77–84.CrossRefPubMed
44.
Zurück zum Zitat Abrantes AM, Strong DR, Ramsey SE, Kazura AN, Brown RA. HIV-risk behaviors among psychiatrically hospitalized adolescents with and without comorbid SUD. J Dual Diagn. 2006;2(3):85–100.CrossRefPubMed Abrantes AM, Strong DR, Ramsey SE, Kazura AN, Brown RA. HIV-risk behaviors among psychiatrically hospitalized adolescents with and without comorbid SUD. J Dual Diagn. 2006;2(3):85–100.CrossRefPubMed
45.
Zurück zum Zitat Bauer LO. A family history of psychopathology modifies the decrement in cognitive control among patients with HIV/AIDS. Brain Cogn. 2008;67(1):103–14.CrossRefPubMed Bauer LO. A family history of psychopathology modifies the decrement in cognitive control among patients with HIV/AIDS. Brain Cogn. 2008;67(1):103–14.CrossRefPubMed
46.
Zurück zum Zitat Brown ES, Rush AJ, McEwen BS. Hippocampal remodeling and damage by corticosteroids: implications for mood disorders. Neuropsychopharmacology. 1999;21(4):474–84.CrossRefPubMed Brown ES, Rush AJ, McEwen BS. Hippocampal remodeling and damage by corticosteroids: implications for mood disorders. Neuropsychopharmacology. 1999;21(4):474–84.CrossRefPubMed
47.
Zurück zum Zitat Perry W, Braff DL. Information-processing deficits and thought disorder in schizophrenia. Am J Psychiatry. 1994;151(3):363–7.PubMed Perry W, Braff DL. Information-processing deficits and thought disorder in schizophrenia. Am J Psychiatry. 1994;151(3):363–7.PubMed
48.
Zurück zum Zitat Centers for Disease Control and Prevention. HIV/AIDS Surveillance Report. Atlanta: U.S. Department of Health and Human Services; 2006. Centers for Disease Control and Prevention. HIV/AIDS Surveillance Report. Atlanta: U.S. Department of Health and Human Services; 2006.
49.
Zurück zum Zitat Teplin LA, Elkington KS, McClelland GM, et al. Major mental disorders, substance use disorders, comorbidity, and HIV-AIDS risk behaviors in juvenile detainees. Psychiatr Serv. 2005;56(7):823–8.CrossRefPubMed Teplin LA, Elkington KS, McClelland GM, et al. Major mental disorders, substance use disorders, comorbidity, and HIV-AIDS risk behaviors in juvenile detainees. Psychiatr Serv. 2005;56(7):823–8.CrossRefPubMed
50.
Zurück zum Zitat Stacy AW, Newcomb MD, Ames SL. Implicit cognition and HIV risk behavior. J Behav Med. 2000;23(5):475.CrossRefPubMed Stacy AW, Newcomb MD, Ames SL. Implicit cognition and HIV risk behavior. J Behav Med. 2000;23(5):475.CrossRefPubMed
51.
Zurück zum Zitat Fromme K, D’Amico EJ, Katz EC. Intoxicated sexual risk taking: an expectancy or cognitive impairment explanation? J Stud Alcohol. 1999;60(1):54–63.PubMed Fromme K, D’Amico EJ, Katz EC. Intoxicated sexual risk taking: an expectancy or cognitive impairment explanation? J Stud Alcohol. 1999;60(1):54–63.PubMed
52.
Zurück zum Zitat Dolezal C, Meyer-Bahlburg HFL, Remien RH, Petkova E. Substance use during sex and sensation seeking as predictors of sexual risk behavior among HIV+ and HIV− gay men. AIDS Behav. 1997;1(1):19–28.CrossRef Dolezal C, Meyer-Bahlburg HFL, Remien RH, Petkova E. Substance use during sex and sensation seeking as predictors of sexual risk behavior among HIV+ and HIV− gay men. AIDS Behav. 1997;1(1):19–28.CrossRef
53.
Zurück zum Zitat Gonzalez R, Vassileva J, Bechara A, et al. The influence of executive functions, sensation seeking, and HIV serostatus on the risky sexual practices of substance-dependent individuals. J Int Neuropsychol Soc. 2005;11(2):121–31.CrossRefPubMed Gonzalez R, Vassileva J, Bechara A, et al. The influence of executive functions, sensation seeking, and HIV serostatus on the risky sexual practices of substance-dependent individuals. J Int Neuropsychol Soc. 2005;11(2):121–31.CrossRefPubMed
54.
Zurück zum Zitat Loxley W, Davidson R. How rational is needle sharing to young injecting drug users? Addict Res Theory. 1998;6(6):499–515.CrossRef Loxley W, Davidson R. How rational is needle sharing to young injecting drug users? Addict Res Theory. 1998;6(6):499–515.CrossRef
55.
Zurück zum Zitat Mitchell MM, Severtson SG, Latimer WW. Interaction of cognitive performance and knowing someone who has died from AIDS on HIV risk behaviors. AIDS Educ Prev. 2007;19(4):289–97.CrossRefPubMed Mitchell MM, Severtson SG, Latimer WW. Interaction of cognitive performance and knowing someone who has died from AIDS on HIV risk behaviors. AIDS Educ Prev. 2007;19(4):289–97.CrossRefPubMed
56.
Zurück zum Zitat De Castro S, Sabate E. Adherence to heroin dependence therapies and human immunodeficiency virus/acquired immunodeficiency syndrome infection rates among drug abusers. Clin Infect Dis. 2003;37(s5):S464–7.CrossRefPubMed De Castro S, Sabate E. Adherence to heroin dependence therapies and human immunodeficiency virus/acquired immunodeficiency syndrome infection rates among drug abusers. Clin Infect Dis. 2003;37(s5):S464–7.CrossRefPubMed
57.
Zurück zum Zitat Wong KH, Lee SS, Lim WL, Low HK. Adherence to methadone is associated with a lower level of HIV-related risk behaviors in drug users. J Subst Abuse Treat. 2003;24(3):233–9.CrossRefPubMed Wong KH, Lee SS, Lim WL, Low HK. Adherence to methadone is associated with a lower level of HIV-related risk behaviors in drug users. J Subst Abuse Treat. 2003;24(3):233–9.CrossRefPubMed
58.
Zurück zum Zitat Avants SK, Margolin A, McKee S. A path analysis of cognitive, affective, and behavioral predictors of treatment response in a methadone maintenance program. J Subst Abuse. 2000;11(3):215–30.CrossRefPubMed Avants SK, Margolin A, McKee S. A path analysis of cognitive, affective, and behavioral predictors of treatment response in a methadone maintenance program. J Subst Abuse. 2000;11(3):215–30.CrossRefPubMed
59.
Zurück zum Zitat Passetti F, Clark L, Mehta MA, Joyce E, King M. Neuropsychological predictors of clinical outcome in opiate addiction. Drug Alcohol Depend. 2008;94(1–3):82–91.CrossRefPubMed Passetti F, Clark L, Mehta MA, Joyce E, King M. Neuropsychological predictors of clinical outcome in opiate addiction. Drug Alcohol Depend. 2008;94(1–3):82–91.CrossRefPubMed
60.
Zurück zum Zitat Paulus MP, Tapert SF, Schuckit MA. Neural activation patterns of methamphetamine-dependent subjects during decision making predict relapse. Arch Gen Psychiatry. 2005;62(7):761–8.CrossRefPubMed Paulus MP, Tapert SF, Schuckit MA. Neural activation patterns of methamphetamine-dependent subjects during decision making predict relapse. Arch Gen Psychiatry. 2005;62(7):761–8.CrossRefPubMed
61.
Zurück zum Zitat Hirsch MS, Conway B, D’Aquila RT, et al. Antiretroviral drug resistance testing in adults with HIV infection: implications for clinical management. International AIDS Society—USA Panel. JAMA. 1998;279(24):1984–91.CrossRefPubMed Hirsch MS, Conway B, D’Aquila RT, et al. Antiretroviral drug resistance testing in adults with HIV infection: implications for clinical management. International AIDS Society—USA Panel. JAMA. 1998;279(24):1984–91.CrossRefPubMed
62.
Zurück zum Zitat Wainberg MA, Friedland G. Public health implications of antiretroviral therapy and HIV drug resistance. JAMA. 1998;279(24):1977–83.CrossRefPubMed Wainberg MA, Friedland G. Public health implications of antiretroviral therapy and HIV drug resistance. JAMA. 1998;279(24):1977–83.CrossRefPubMed
63.
Zurück zum Zitat Hinkin CH, Castellon SA, Durvasula RS, et al. Medication adherence among HIV+ adults: effects of cognitive dysfunction and regimen complexity. Neurology. 2002;59(12):1944–50.PubMed Hinkin CH, Castellon SA, Durvasula RS, et al. Medication adherence among HIV+ adults: effects of cognitive dysfunction and regimen complexity. Neurology. 2002;59(12):1944–50.PubMed
64.
Zurück zum Zitat Hinkin CH, Hardy DJ, Mason KI, et al. Medication adherence in HIV-infected adults: effect of patient age, cognitive status, and substance abuse. AIDS. 2004;18(Suppl 1):S19–25.PubMed Hinkin CH, Hardy DJ, Mason KI, et al. Medication adherence in HIV-infected adults: effect of patient age, cognitive status, and substance abuse. AIDS. 2004;18(Suppl 1):S19–25.PubMed
65.
Zurück zum Zitat Woods SP, Dawson MS, Weber E, et al. Timing is everything: antiretroviral nonadherence is associated with impairment in time-based prospective memory. J Int Neuropsychol Soc. 2009;15(1):42–52.CrossRefPubMed Woods SP, Dawson MS, Weber E, et al. Timing is everything: antiretroviral nonadherence is associated with impairment in time-based prospective memory. J Int Neuropsychol Soc. 2009;15(1):42–52.CrossRefPubMed
66.
Zurück zum Zitat Contardo C, Black AC, Beauvais J, Dieckhaus K, Rosen MI. Relationship of prospective memory to neuropsychological function and antiretroviral adherence. Arch Clin Neuropsychol. 2009;24(6):547–54.CrossRefPubMed Contardo C, Black AC, Beauvais J, Dieckhaus K, Rosen MI. Relationship of prospective memory to neuropsychological function and antiretroviral adherence. Arch Clin Neuropsychol. 2009;24(6):547–54.CrossRefPubMed
67.
Zurück zum Zitat Waldrop-Valverde D, Jones DL, Weiss S, Kumar M, Metsch L. The effects of low literacy and cognitive impairment on medication adherence in HIV-positive injecting drug users. AIDS Care. 2008;20(10):1202–10.CrossRefPubMed Waldrop-Valverde D, Jones DL, Weiss S, Kumar M, Metsch L. The effects of low literacy and cognitive impairment on medication adherence in HIV-positive injecting drug users. AIDS Care. 2008;20(10):1202–10.CrossRefPubMed
68.
Zurück zum Zitat Blume AW, Davis JM, Schmaling KB. Neurocognitive dysfunction in dually-diagnosed patients: a potential roadblock to motivating behavior change. J Psychoactive Drugs. 1999;31(2):111–5.PubMed Blume AW, Davis JM, Schmaling KB. Neurocognitive dysfunction in dually-diagnosed patients: a potential roadblock to motivating behavior change. J Psychoactive Drugs. 1999;31(2):111–5.PubMed
69.
Zurück zum Zitat Morgenstern J, Bates ME. Effects of executive function impairment on change processes and substance use outcomes in 12-step treatment. J Stud Alcohol. 1999;60(6):846–55.PubMed Morgenstern J, Bates ME. Effects of executive function impairment on change processes and substance use outcomes in 12-step treatment. J Stud Alcohol. 1999;60(6):846–55.PubMed
70.
Zurück zum Zitat Blume AW, Marlatt GA. The role of executive cognitive functions in changing substance use: what we know and what we need to know. Ann Behav Med. 2009;37(2):117–25.CrossRefPubMed Blume AW, Marlatt GA. The role of executive cognitive functions in changing substance use: what we know and what we need to know. Ann Behav Med. 2009;37(2):117–25.CrossRefPubMed
71.
Zurück zum Zitat Altice FL, Sullivan LE, Smith-Rohrberg D, et al. The potential role of buprenorphine in the treatment of opioid dependence in HIV-infected individuals and in HIV infection prevention. Clin Infect Dis. 2006;43(Suppl 4):S178–83.CrossRefPubMed Altice FL, Sullivan LE, Smith-Rohrberg D, et al. The potential role of buprenorphine in the treatment of opioid dependence in HIV-infected individuals and in HIV infection prevention. Clin Infect Dis. 2006;43(Suppl 4):S178–83.CrossRefPubMed
72.
Zurück zum Zitat Mintzer MZ, Correia CJ, Strain EC. A dose-effect study of repeated administration of buprenorphine/naloxone on performance in opioid-dependent volunteers. Drug Alcohol Depend. 2004;74(2):205–9.CrossRefPubMed Mintzer MZ, Correia CJ, Strain EC. A dose-effect study of repeated administration of buprenorphine/naloxone on performance in opioid-dependent volunteers. Drug Alcohol Depend. 2004;74(2):205–9.CrossRefPubMed
73.
Zurück zum Zitat Kouri EM, Lukas SE, Mendelson JH. P300 assessment of opiate and cocaine users: effects of detoxification and buprenorphine treatment. Biol Psychiatry. 1996;40(7):617–28.CrossRefPubMed Kouri EM, Lukas SE, Mendelson JH. P300 assessment of opiate and cocaine users: effects of detoxification and buprenorphine treatment. Biol Psychiatry. 1996;40(7):617–28.CrossRefPubMed
74.
Zurück zum Zitat Pirastu R, Fais R, Messina M, et al. Impaired decision-making in opiate-dependent subjects: effect of pharmacological therapies. Drug Alcohol Depend. 2006;83(2):163–8.CrossRefPubMed Pirastu R, Fais R, Messina M, et al. Impaired decision-making in opiate-dependent subjects: effect of pharmacological therapies. Drug Alcohol Depend. 2006;83(2):163–8.CrossRefPubMed
75.
Zurück zum Zitat Bruce RD, Govindasamy S, Sylla L, et al. Case series of buprenorphine injectors in Kuala Lumpur, Malaysia. Am J Drug Alcohol Abuse. 2008;34(4):511–7.CrossRefPubMed Bruce RD, Govindasamy S, Sylla L, et al. Case series of buprenorphine injectors in Kuala Lumpur, Malaysia. Am J Drug Alcohol Abuse. 2008;34(4):511–7.CrossRefPubMed
76.
Zurück zum Zitat Greenwald M, Johanson C-E, Bueller J, et al. Buprenorphine duration of action: mu-opioid receptor availability and pharmacokinetic and behavioral indices. Biol Psychiatry. 2007;61(1):101–10.CrossRefPubMed Greenwald M, Johanson C-E, Bueller J, et al. Buprenorphine duration of action: mu-opioid receptor availability and pharmacokinetic and behavioral indices. Biol Psychiatry. 2007;61(1):101–10.CrossRefPubMed
77.
Zurück zum Zitat Pachet AK, Wisniewski AM. The effects of lithium on cognition: an updated review. Psychopharmacology (Berl). 2003;170(3):225–34.CrossRef Pachet AK, Wisniewski AM. The effects of lithium on cognition: an updated review. Psychopharmacology (Berl). 2003;170(3):225–34.CrossRef
78.
Zurück zum Zitat Letendre SL, Woods SP, Ellis RJ, et al. Lithium improves HIV-associated neurocognitive impairment. AIDS. 2006;20(14):1885–8.CrossRefPubMed Letendre SL, Woods SP, Ellis RJ, et al. Lithium improves HIV-associated neurocognitive impairment. AIDS. 2006;20(14):1885–8.CrossRefPubMed
79.
Zurück zum Zitat Douglas IJ, Smeeth L. Exposure to antipsychotics and risk of stroke: self controlled case series study. BMJ. 2008;337:a1227.CrossRefPubMed Douglas IJ, Smeeth L. Exposure to antipsychotics and risk of stroke: self controlled case series study. BMJ. 2008;337:a1227.CrossRefPubMed
80.
Zurück zum Zitat Cuesta MJ, Peralta V, Zarzuela A. Effects of olanzapine and other antipsychotics on cognitive function in chronic schizophrenia: a longitudinal study. Schizophr Res. 2001;48(1):17–28.CrossRefPubMed Cuesta MJ, Peralta V, Zarzuela A. Effects of olanzapine and other antipsychotics on cognitive function in chronic schizophrenia: a longitudinal study. Schizophr Res. 2001;48(1):17–28.CrossRefPubMed
81.
Zurück zum Zitat Meltzer HY, McGurk SR. The effects of clozapine, risperidone, and olanzapine on cognitive function in schizophrenia. Schizophr Bull. 1999;25(2):233–56.PubMed Meltzer HY, McGurk SR. The effects of clozapine, risperidone, and olanzapine on cognitive function in schizophrenia. Schizophr Bull. 1999;25(2):233–56.PubMed
82.
Zurück zum Zitat Robertson KR, Robertson WT, Ford S, et al. Highly active antiretroviral therapy improves neurocognitive functioning. J Acquir Immune Defic Syndr. 2004;36(1):562–6.CrossRefPubMed Robertson KR, Robertson WT, Ford S, et al. Highly active antiretroviral therapy improves neurocognitive functioning. J Acquir Immune Defic Syndr. 2004;36(1):562–6.CrossRefPubMed
83.
Zurück zum Zitat Springer S, Chen S, Altice F. Depression and symptomatic response among HIV-infected drug users enrolled in a randomized controlled trial of directly administered antiretroviral therapy. AIDS Care. 2009;21(8):976–83.CrossRefPubMed Springer S, Chen S, Altice F. Depression and symptomatic response among HIV-infected drug users enrolled in a randomized controlled trial of directly administered antiretroviral therapy. AIDS Care. 2009;21(8):976–83.CrossRefPubMed
84.
Zurück zum Zitat Cysique LAJ, Maruff P, Brew BJ. Antiretroviral therapy in hiv infection: are neurologically active drugs important? Arch Neurol. 2004;61(11):1699–704.CrossRefPubMed Cysique LAJ, Maruff P, Brew BJ. Antiretroviral therapy in hiv infection: are neurologically active drugs important? Arch Neurol. 2004;61(11):1699–704.CrossRefPubMed
85.
Zurück zum Zitat Antinori A, Giancola ML, Grisetti S, et al. Factors influencing virological response to antiretroviral drugs in cerebrospinal fluid of advanced HIV-1-infected patients. AIDS. 2002;16(14):1867–76.CrossRefPubMed Antinori A, Giancola ML, Grisetti S, et al. Factors influencing virological response to antiretroviral drugs in cerebrospinal fluid of advanced HIV-1-infected patients. AIDS. 2002;16(14):1867–76.CrossRefPubMed
86.
Zurück zum Zitat Cysique LA, Vaida F, Letendre S, et al. Dynamics of cognitive change in impaired HIV-positive patients initiating antiretroviral therapy. Neurology. 2009;73(5):342–8.CrossRefPubMed Cysique LA, Vaida F, Letendre S, et al. Dynamics of cognitive change in impaired HIV-positive patients initiating antiretroviral therapy. Neurology. 2009;73(5):342–8.CrossRefPubMed
87.
Zurück zum Zitat Yilmaz A, Price RW, Spudich S, et al. Persistent intrathecal immune activation in HIV-1-infected individuals on antiretroviral therapy. J Acquir Immune Defic Syndr. 2008;47(2):168–73.CrossRefPubMed Yilmaz A, Price RW, Spudich S, et al. Persistent intrathecal immune activation in HIV-1-infected individuals on antiretroviral therapy. J Acquir Immune Defic Syndr. 2008;47(2):168–73.CrossRefPubMed
88.
Zurück zum Zitat Tozzi V, Balestra P, Galgani S, et al. Positive and sustained effects of highly active antiretroviral therapy on HIV-1-associated neurocognitive impairment. AIDS. 1999;13(14):1889–97.CrossRefPubMed Tozzi V, Balestra P, Galgani S, et al. Positive and sustained effects of highly active antiretroviral therapy on HIV-1-associated neurocognitive impairment. AIDS. 1999;13(14):1889–97.CrossRefPubMed
89.
Zurück zum Zitat McCutchan JA, Wu JW, Robertson K, et al. HIV suppression by HAART preserves cognitive function in advanced, immune-reconstituted AIDS patients. AIDS. 2007;21(9):1109–17.CrossRefPubMed McCutchan JA, Wu JW, Robertson K, et al. HIV suppression by HAART preserves cognitive function in advanced, immune-reconstituted AIDS patients. AIDS. 2007;21(9):1109–17.CrossRefPubMed
90.
Zurück zum Zitat Cespedes MS, Aberg JA. Neuropsychiatric complications of antiretroviral therapy. Drug Saf. 2006;29(10):865–74.CrossRefPubMed Cespedes MS, Aberg JA. Neuropsychiatric complications of antiretroviral therapy. Drug Saf. 2006;29(10):865–74.CrossRefPubMed
91.
Zurück zum Zitat Velligan DI, Diamond PM, Mintz J, et al. The use of individually tailored environmental supports to improve medication adherence and outcomes in schizophrenia. Schizophr Bull. 2008;34(3):483–93.CrossRefPubMed Velligan DI, Diamond PM, Mintz J, et al. The use of individually tailored environmental supports to improve medication adherence and outcomes in schizophrenia. Schizophr Bull. 2008;34(3):483–93.CrossRefPubMed
92.
Zurück zum Zitat Wexler BE, Anderson M, Fulbright RK, Gore JC. Preliminary evidence of improved verbal working memory performance and normalization of task-related frontal lobe activation in schizophrenia following cognitive exercises. Am J Psychiatry. 2000;157(10):1694–7.CrossRefPubMed Wexler BE, Anderson M, Fulbright RK, Gore JC. Preliminary evidence of improved verbal working memory performance and normalization of task-related frontal lobe activation in schizophrenia following cognitive exercises. Am J Psychiatry. 2000;157(10):1694–7.CrossRefPubMed
93.
Zurück zum Zitat Fals-Stewart W, Schafer J, Lucente S, Rustine T, Brown L. Neurobehavioral consequences of prolonged alcohol and substance abuse: a review of findings and treatment implications. Clin Psychol Rev. 1994;14(8):755–78.CrossRef Fals-Stewart W, Schafer J, Lucente S, Rustine T, Brown L. Neurobehavioral consequences of prolonged alcohol and substance abuse: a review of findings and treatment implications. Clin Psychol Rev. 1994;14(8):755–78.CrossRef
94.
Zurück zum Zitat Avants SK, Margolin A, Usubiaga MH, Doebrick C. Targeting HIV-related outcomes with intravenous drug users maintained on methadone: a randomized clinical trial of a harm reduction group therapy. J Subst Abuse Treat. 2004;26(2):67–78.CrossRefPubMed Avants SK, Margolin A, Usubiaga MH, Doebrick C. Targeting HIV-related outcomes with intravenous drug users maintained on methadone: a randomized clinical trial of a harm reduction group therapy. J Subst Abuse Treat. 2004;26(2):67–78.CrossRefPubMed
95.
Zurück zum Zitat Margolin A, Kelly Avants S, Warburton LA, Hawkins KA, Shi J. A randomized clinical trial of a manual-guided risk reduction intervention for HIV-positive injection drug users. Health Psychol. 2003;22(2):223–8.CrossRefPubMed Margolin A, Kelly Avants S, Warburton LA, Hawkins KA, Shi J. A randomized clinical trial of a manual-guided risk reduction intervention for HIV-positive injection drug users. Health Psychol. 2003;22(2):223–8.CrossRefPubMed
96.
Zurück zum Zitat Fisher WA, Fisher JD, Pryor JB, Reeder GD. A general social psychological model for changing AIDS risk behavior. The social psychology of HIV infection. Hillsdale: Lawrence Erlbaum Associates; 1993. p. 127–53. Fisher WA, Fisher JD, Pryor JB, Reeder GD. A general social psychological model for changing AIDS risk behavior. The social psychology of HIV infection. Hillsdale: Lawrence Erlbaum Associates; 1993. p. 127–53.
97.
Zurück zum Zitat Carey MP, Carey KB, Maisto SA, et al. Reducing HIV-risk behavior among adults receiving outpatient psychiatric treatment: results from a randomized controlled trial. J Consult Clin Psychol. 2004;72(2):252–68.CrossRefPubMed Carey MP, Carey KB, Maisto SA, et al. Reducing HIV-risk behavior among adults receiving outpatient psychiatric treatment: results from a randomized controlled trial. J Consult Clin Psychol. 2004;72(2):252–68.CrossRefPubMed
98.
Zurück zum Zitat Morin SF, Shade SB, Steward WT, et al. A behavioral intervention reduces HIV transmission risk by promoting sustained serosorting practices among HIV-infected men who have sex with men. J Acquir Immune Defic Syndr. 2008;49(5):544–51.CrossRefPubMed Morin SF, Shade SB, Steward WT, et al. A behavioral intervention reduces HIV transmission risk by promoting sustained serosorting practices among HIV-infected men who have sex with men. J Acquir Immune Defic Syndr. 2008;49(5):544–51.CrossRefPubMed
99.
Zurück zum Zitat Carrico AW, Chesney MA, Johnson MO, et al. Randomized controlled trial of a cognitive-behavioral intervention for HIV-positive persons: an investigation of treatment effects on psychosocial adjustment. AIDS Behav. 2009;13(3):555–63.CrossRefPubMed Carrico AW, Chesney MA, Johnson MO, et al. Randomized controlled trial of a cognitive-behavioral intervention for HIV-positive persons: an investigation of treatment effects on psychosocial adjustment. AIDS Behav. 2009;13(3):555–63.CrossRefPubMed
100.
Zurück zum Zitat Kalichman SC. Co-occurrence of treatment nonadherence and continued HIV transmission risk behaviors: implications for positive prevention interventions. Psychosom Med. 2008;70(5):593–7.CrossRefPubMed Kalichman SC. Co-occurrence of treatment nonadherence and continued HIV transmission risk behaviors: implications for positive prevention interventions. Psychosom Med. 2008;70(5):593–7.CrossRefPubMed
101.
Zurück zum Zitat Tross S, Campbell A, Cohen L, et al. Effectiveness of HIV/STD sexual risk reduction groups for women in substance abuse treatment programs: results of a NIDA clinical trials network trial. J Acquir Immune Defic Syndr. 2008;48(5):581.CrossRefPubMed Tross S, Campbell A, Cohen L, et al. Effectiveness of HIV/STD sexual risk reduction groups for women in substance abuse treatment programs: results of a NIDA clinical trials network trial. J Acquir Immune Defic Syndr. 2008;48(5):581.CrossRefPubMed
102.
Zurück zum Zitat Calsyn DA, Hatch-Maillette M, Tross S, et al. Motivational and skills training HIV/sexually transmitted infection sexual risk reduction groups for men. J Subst Abuse Treat. 2009;37(2):138–50.CrossRefPubMed Calsyn DA, Hatch-Maillette M, Tross S, et al. Motivational and skills training HIV/sexually transmitted infection sexual risk reduction groups for men. J Subst Abuse Treat. 2009;37(2):138–50.CrossRefPubMed
Metadaten
Titel
Neurocognitive Impairment and HIV Risk Factors: A Reciprocal Relationship
verfasst von
Pria Anand
Sandra A. Springer
Michael M. Copenhaver
Frederick L. Altice
Publikationsdatum
01.12.2010
Verlag
Springer US
Erschienen in
AIDS and Behavior / Ausgabe 6/2010
Print ISSN: 1090-7165
Elektronische ISSN: 1573-3254
DOI
https://doi.org/10.1007/s10461-010-9684-1

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