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Siderocalins: siderophore-binding proteins of the innate immune system

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Abstract

Recent studies have revealed that the mammalian immune system directly interferes with siderophore-mediated iron acquisition through siderophore-binding proteins and that the association of certain siderophores, or siderophore modifications, with virulence is a direct response of pathogens to evade these defenses.

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  1. Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA

    Matthew C. Clifton, Colin Corrent & Roland K. Strong

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  1. Matthew C. Clifton
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  2. Colin Corrent
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  3. Roland K. Strong
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Correspondence to Roland K. Strong.

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Clifton, M.C., Corrent, C. & Strong, R.K. Siderocalins: siderophore-binding proteins of the innate immune system. Biometals 22, 557–564 (2009). https://doi.org/10.1007/s10534-009-9207-6

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