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Erschienen in: Cancer Causes & Control 11/2012

01.11.2012 | Original paper

Regular dental visits are associated with earlier stage at diagnosis for oral and pharyngeal cancer

verfasst von: Scott M. Langevin, Dominique S. Michaud, Melissa Eliot, Edward S. Peters, Michael D. McClean, Karl T. Kelsey

Erschienen in: Cancer Causes & Control | Ausgabe 11/2012

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Abstract

Purpose

Oral and pharyngeal cancer patients diagnosed at an advanced stage experience increased morbidity and mortality relative to those with localized disease. The aim of this study was to assess the impact of dental insurance status and regularity of dental visits on early detection of oral and pharyngeal cancer.

Methods

We examined the relationship of dental insurance and frequency of dental visits with stage at diagnosis among 441 oral and pharyngeal cancer cases from a population-based study of head and neck cancer. Ordinal logistic regression models were used to assess the association with stage, and tumor (T) and nodal (N) classification.

Results

Never or rarely going to the dentist was associated with being diagnosed at higher stage for oral and pharyngeal cancer (cumulative OR = 2.28, 95 % CI: 1.02–5.10) and oral cancer (cumulative OR = 9.17, 95 % CI: 2.70–31.15) compared to those going to the dentist at least annually. Oral and pharyngeal cancer patients who went to the dentist infrequently (cumulative OR = 1.82, 95 % CI: 1.09–3.05) or rarely/never (cumulative OR = 3.24, 95 % CI: 1.59–6.57) were diagnosed with a higher T classification compared with those who went at least annually.

Conclusions

Receipt of regular dental examinations at least annually may reduce the public health burden of oral and pharyngeal cancer by facilitating earlier detection of the disease.
Literatur
1.
Zurück zum Zitat Siegel R, Ward E, Brawley O, Jemal A (2011) Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths. CA Cancer J Clin 61(4):212–236. doi:10.3322/caac.20121 PubMedCrossRef Siegel R, Ward E, Brawley O, Jemal A (2011) Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths. CA Cancer J Clin 61(4):212–236. doi:10.​3322/​caac.​20121 PubMedCrossRef
2.
Zurück zum Zitat Carvalho AL, Nishimoto IN, Califano JA, Kowalski LP (2005) Trends in incidence and prognosis for head and neck cancer in the United States: a site-specific analysis of the SEER database. Int J Cancer 114(5):806–816. doi:10.1002/ijc.20740 PubMedCrossRef Carvalho AL, Nishimoto IN, Califano JA, Kowalski LP (2005) Trends in incidence and prognosis for head and neck cancer in the United States: a site-specific analysis of the SEER database. Int J Cancer 114(5):806–816. doi:10.​1002/​ijc.​20740 PubMedCrossRef
3.
Zurück zum Zitat Howlader N, Noone AM, Krapcho M, Neyman N, Aminou R, Waldron W, Altekruse SF, Kosary CL, Ruhl J, Tatalovich Z, Cho H, Mariotto A, Eisner MP, Lewis DR, Chen HS, Feuer EJ, Cronin KA, Edwards DK (2011) SEER cancer statistics, review, 1975–2008. National Cancer Institute, Bethesda, MD Howlader N, Noone AM, Krapcho M, Neyman N, Aminou R, Waldron W, Altekruse SF, Kosary CL, Ruhl J, Tatalovich Z, Cho H, Mariotto A, Eisner MP, Lewis DR, Chen HS, Feuer EJ, Cronin KA, Edwards DK (2011) SEER cancer statistics, review, 1975–2008. National Cancer Institute, Bethesda, MD
4.
Zurück zum Zitat Healthy People 2010: Oral Health (2000) U.S. Department of Health and Human Services, Washington, DC Healthy People 2010: Oral Health (2000) U.S. Department of Health and Human Services, Washington, DC
6.
Zurück zum Zitat Wineland AM, Stack BC Jr (2008) Modern methods to predict costs for the treatment and management of head and neck cancer patients: examples of methods used in the current literature. Curr Opin Otolaryngol Head Neck Surg 16(2):113–116PubMedCrossRef Wineland AM, Stack BC Jr (2008) Modern methods to predict costs for the treatment and management of head and neck cancer patients: examples of methods used in the current literature. Curr Opin Otolaryngol Head Neck Surg 16(2):113–116PubMedCrossRef
7.
Zurück zum Zitat Warnakulasuriya KA, Johnson NW (1996) Strengths and weaknesses of screening programmes for oral malignancies and potentially malignant lesions. Eur J Cancer Prev 5(2):93–98PubMedCrossRef Warnakulasuriya KA, Johnson NW (1996) Strengths and weaknesses of screening programmes for oral malignancies and potentially malignant lesions. Eur J Cancer Prev 5(2):93–98PubMedCrossRef
8.
Zurück zum Zitat Lim K, Moles DR, Downer MC, Speight PM (2003) Opportunistic screening for oral cancer and precancer in general dental practice: results of a demonstration study. Br Dent J 194(9):497–502; discussion 493. doi:10.1038/sj.bdj.4810069 Lim K, Moles DR, Downer MC, Speight PM (2003) Opportunistic screening for oral cancer and precancer in general dental practice: results of a demonstration study. Br Dent J 194(9):497–502; discussion 493. doi:10.​1038/​sj.​bdj.​4810069
9.
Zurück zum Zitat Speight PM, Palmer S, Moles DR, Downer MC, Smith DH, Henriksson M, Augustovski F (2006) The cost-effectiveness of screening for oral cancer in primary care. Health Technol Assess 10(14):1–144, iii–iv Speight PM, Palmer S, Moles DR, Downer MC, Smith DH, Henriksson M, Augustovski F (2006) The cost-effectiveness of screening for oral cancer in primary care. Health Technol Assess 10(14):1–144, iii–iv
11.
Zurück zum Zitat Yusof ZY, Netuveli G, Ramli AS, Sheiham A (2006) Is opportunistic oral cancer screening by dentists feasible? An analysis of the patterns of dental attendance of a nationally representative sample over 10 years. Oral Health Prev Dent 4(3):165–171PubMed Yusof ZY, Netuveli G, Ramli AS, Sheiham A (2006) Is opportunistic oral cancer screening by dentists feasible? An analysis of the patterns of dental attendance of a nationally representative sample over 10 years. Oral Health Prev Dent 4(3):165–171PubMed
12.
13.
Zurück zum Zitat Mashberg A (2000) Diagnosis of early oral and oropharyngeal squamous carcinoma: obstacles and their amelioration. Oral Oncol 36(3):253–255PubMedCrossRef Mashberg A (2000) Diagnosis of early oral and oropharyngeal squamous carcinoma: obstacles and their amelioration. Oral Oncol 36(3):253–255PubMedCrossRef
15.
Zurück zum Zitat MacCarthy D, Flint SR, Healy C, Stassen LF (2011) Oral and neck examination for early detection of oral cancer—a practical guide. J Ir Dent Assoc 57(4):195–199PubMed MacCarthy D, Flint SR, Healy C, Stassen LF (2011) Oral and neck examination for early detection of oral cancer—a practical guide. J Ir Dent Assoc 57(4):195–199PubMed
16.
Zurück zum Zitat Oral Health U.S., 2002 (2002) National Institute of Dental and Craniofacial Research of the National Institutes of Health, Rockville, MD Oral Health U.S., 2002 (2002) National Institute of Dental and Craniofacial Research of the National Institutes of Health, Rockville, MD
17.
Zurück zum Zitat Oral Health, U.S. 2002 Annual Report (2002) National Institute of Dental and Craniofacial Research Bethesda, MD Oral Health, U.S. 2002 Annual Report (2002) National Institute of Dental and Craniofacial Research Bethesda, MD
19.
Zurück zum Zitat Kwok J, Langevin SM, Argiris A, Grandis JR, Gooding WE, Taioli E (2010) The impact of health insurance status on the survival of patients with head and neck cancer. Cancer 116(2):476–485. doi:10.1002/cncr.24774 PubMedCrossRef Kwok J, Langevin SM, Argiris A, Grandis JR, Gooding WE, Taioli E (2010) The impact of health insurance status on the survival of patients with head and neck cancer. Cancer 116(2):476–485. doi:10.​1002/​cncr.​24774 PubMedCrossRef
21.
22.
Zurück zum Zitat Applebaum KM, McClean MD, Nelson HH, Marsit CJ, Christensen BC, Kelsey KT (2009) Smoking modifies the relationship between XRCC1 haplotypes and HPV16-negative head and neck squamous cell carcinoma. Int J Cancer 124(11):2690–2696. doi:10.1002/ijc.24256 PubMedCrossRef Applebaum KM, McClean MD, Nelson HH, Marsit CJ, Christensen BC, Kelsey KT (2009) Smoking modifies the relationship between XRCC1 haplotypes and HPV16-negative head and neck squamous cell carcinoma. Int J Cancer 124(11):2690–2696. doi:10.​1002/​ijc.​24256 PubMedCrossRef
23.
Zurück zum Zitat Liang C, McClean MD, Marsit C, Christensen B, Peters E, Nelson HH, Kelsey KT (2009) A population-based case–control study of marijuana use and head and neck squamous cell carcinoma. Cancer Prev Res (Phila) 2(8):759–768. doi:10.1158/1940-6207.CAPR-09-0048 CrossRef Liang C, McClean MD, Marsit C, Christensen B, Peters E, Nelson HH, Kelsey KT (2009) A population-based case–control study of marijuana use and head and neck squamous cell carcinoma. Cancer Prev Res (Phila) 2(8):759–768. doi:10.​1158/​1940-6207.​CAPR-09-0048 CrossRef
24.
Zurück zum Zitat D’Agostino RB, Belanger A, D’Agostino RBJ (1990) A suggestion for using powerful and informative tests of normality. Am Stat 44(4):316–321 D’Agostino RB, Belanger A, D’Agostino RBJ (1990) A suggestion for using powerful and informative tests of normality. Am Stat 44(4):316–321
25.
Zurück zum Zitat Mccullagh P (1980) Regression-models for ordinal data. J R Stat Soc B Met 42(2):109–142 Mccullagh P (1980) Regression-models for ordinal data. J R Stat Soc B Met 42(2):109–142
26.
Zurück zum Zitat Edge S, Byrd D, Compton C, Fritz A, Greene F, Trotti A (eds) (2009) American joint committee on cancer staging manual, 7th edn. Springer, New York Edge S, Byrd D, Compton C, Fritz A, Greene F, Trotti A (eds) (2009) American joint committee on cancer staging manual, 7th edn. Springer, New York
27.
Zurück zum Zitat Greenland S, Finkle WD (1995) A critical look at methods for handling missing covariates in epidemiologic regression analyses. Am J Epidemiol 142(12):1255–1264PubMed Greenland S, Finkle WD (1995) A critical look at methods for handling missing covariates in epidemiologic regression analyses. Am J Epidemiol 142(12):1255–1264PubMed
28.
Zurück zum Zitat Brant R (1990) Assessing proportionality in the proportional odds model for ordinal logistic-regression. Biometrics 46(4):1171–1178PubMedCrossRef Brant R (1990) Assessing proportionality in the proportional odds model for ordinal logistic-regression. Biometrics 46(4):1171–1178PubMedCrossRef
29.
Zurück zum Zitat Elwood JM, Gallagher RP (1985) Factors influencing early diagnosis of cancer of the oral cavity. CMAJ 133(7):651–656PubMed Elwood JM, Gallagher RP (1985) Factors influencing early diagnosis of cancer of the oral cavity. CMAJ 133(7):651–656PubMed
32.
Zurück zum Zitat Holmes JD, Dierks EJ, Homer LD, Potter BE (2003) Is detection of oral and oropharyngeal squamous cancer by a dental health care provider associated with a lower stage at diagnosis? J Oral Maxillofac Surg 61(3):285–291. doi:10.1053/joms.2003.50056 PubMedCrossRef Holmes JD, Dierks EJ, Homer LD, Potter BE (2003) Is detection of oral and oropharyngeal squamous cancer by a dental health care provider associated with a lower stage at diagnosis? J Oral Maxillofac Surg 61(3):285–291. doi:10.​1053/​joms.​2003.​50056 PubMedCrossRef
33.
Zurück zum Zitat National Health Expenditure Projections 2010–2020 (2011) Centers for medicare and medicaid services. Office of the Actuary, Baltimore, MD National Health Expenditure Projections 2010–2020 (2011) Centers for medicare and medicaid services. Office of the Actuary, Baltimore, MD
34.
Zurück zum Zitat Applebaum E, Ruhlen TN, Kronenberg FR, Hayes C, Peters ES (2009) Oral cancer knowledge, attitudes and practices: a survey of dentists and primary care physicians in Massachusetts. J Am Dent Assoc 140(4):461–467PubMed Applebaum E, Ruhlen TN, Kronenberg FR, Hayes C, Peters ES (2009) Oral cancer knowledge, attitudes and practices: a survey of dentists and primary care physicians in Massachusetts. J Am Dent Assoc 140(4):461–467PubMed
36.
Zurück zum Zitat Lehew CW, Kaste LM (2007) Oral cancer prevention and early detection knowledge and practices of Illinois dentists—a brief communication. J Public Health Dent 67(2):89–93PubMedCrossRef Lehew CW, Kaste LM (2007) Oral cancer prevention and early detection knowledge and practices of Illinois dentists—a brief communication. J Public Health Dent 67(2):89–93PubMedCrossRef
38.
Zurück zum Zitat Horowitz AM, Drury TF, Canto MT (2000) Practices of Maryland dentists: oral cancer prevention and early detection—baseline data from 1995. Oral Dis 6(5):282–288PubMedCrossRef Horowitz AM, Drury TF, Canto MT (2000) Practices of Maryland dentists: oral cancer prevention and early detection—baseline data from 1995. Oral Dis 6(5):282–288PubMedCrossRef
39.
Zurück zum Zitat Yellowitz JA, Horowitz AM, Drury TF, Goodman HS (2000) Survey of U.S. dentists’ knowledge and opinions about oral pharyngeal cancer. J Am Dent Assoc 131(5):653–661PubMed Yellowitz JA, Horowitz AM, Drury TF, Goodman HS (2000) Survey of U.S. dentists’ knowledge and opinions about oral pharyngeal cancer. J Am Dent Assoc 131(5):653–661PubMed
40.
Zurück zum Zitat Patton LL, Ashe TE, Elter JR, Southerland JH, Strauss RP (2006) Adequacy of training in oral cancer prevention and screening as self-assessed by physicians, nurse practitioners, and dental health professionals. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 102(6):758–764. doi:10.1016/j.tripleo.2005.10.072 PubMedCrossRef Patton LL, Ashe TE, Elter JR, Southerland JH, Strauss RP (2006) Adequacy of training in oral cancer prevention and screening as self-assessed by physicians, nurse practitioners, and dental health professionals. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 102(6):758–764. doi:10.​1016/​j.​tripleo.​2005.​10.​072 PubMedCrossRef
41.
Zurück zum Zitat van der Waal I, de Bree R, Brakenhoff R, Coebergh JW (2011) Early diagnosis in primary oral cancer: is it possible? Med Oral Patol Oral Cir Bucal 16(3):e300–e305PubMedCrossRef van der Waal I, de Bree R, Brakenhoff R, Coebergh JW (2011) Early diagnosis in primary oral cancer: is it possible? Med Oral Patol Oral Cir Bucal 16(3):e300–e305PubMedCrossRef
42.
Zurück zum Zitat Sturgis EM, Cinciripini PM (2007) Trends in head and neck cancer incidence in relation to smoking prevalence: an emerging epidemic of human papillomavirus-associated cancers? Cancer 110(7):1429–1435PubMedCrossRef Sturgis EM, Cinciripini PM (2007) Trends in head and neck cancer incidence in relation to smoking prevalence: an emerging epidemic of human papillomavirus-associated cancers? Cancer 110(7):1429–1435PubMedCrossRef
Metadaten
Titel
Regular dental visits are associated with earlier stage at diagnosis for oral and pharyngeal cancer
verfasst von
Scott M. Langevin
Dominique S. Michaud
Melissa Eliot
Edward S. Peters
Michael D. McClean
Karl T. Kelsey
Publikationsdatum
01.11.2012
Verlag
Springer Netherlands
Erschienen in
Cancer Causes & Control / Ausgabe 11/2012
Print ISSN: 0957-5243
Elektronische ISSN: 1573-7225
DOI
https://doi.org/10.1007/s10552-012-0061-4

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