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Erschienen in: The International Journal of Cardiovascular Imaging 2/2012

01.12.2012 | Original Paper

Assessment of left and right ventricular parameters in healthy Korean volunteers using cardiac magnetic resonance imaging: change in ventricular volume and function based on age, gender and body surface area

verfasst von: Sung-A Chang, Yeon Hyeon Choe, Shin Yi Jang, Sung Mok Kim, Sang-Chol Lee, Jae K. Oh

Erschienen in: The International Journal of Cardiovascular Imaging | Sonderheft 2/2012

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Abstract

The clinical utility of cardiac magnetic resonance imaging (CMR) is growing and is being used predominantly as a means of measuring ventricular function. The normal reference range of ventricular function may vary based on age, sex and ethnicity. At present, most CMR reference values for healthy individuals have been reported from Western countries. The intent of this study was to investigate the normal CMR reference range for left ventricular (LV) and right ventricular (RV) parameters in healthy Koreans. Healthy volunteers between the ages of 20–70 years without any history of cardiovascular disease or associated risk factors were prospectively recruited to be a part of this study. A total of 124 patients were recruited for this study. Steady-state free precession pulse sequences were used to obtain the cine images for LV and RV volume analysis. All parameters were analyzed based on age and gender, and normalized to body surface area (BSA). LV volume, mass and cardiac output were significantly greater in males than in females. However, all of these parameters which are associated with BSA and gender differences disappeared when corrected for BSA. RV volume was less in females even after the data was normalized for BSA. LV and RV volumes normalized for BSA gradually decreased with greater age, whereas the ejection fraction increased with age, thus maintaining the stroke volume index and cardiac index. LV and RV volumes, mass and function values for a healthy population largely depend on BSA and should be evaluated after normalization by BSA. LV parameters show no difference based on gender, but RV volume is less in the female. Greater age is associated with less ventricular volume, suggesting the possibility of volume sensitivity in the elderly.
Literatur
1.
Zurück zum Zitat Bellenger NG, Rajappan K, Rahman SL et al (2004) Effects of carvedilol on left ventricular remodelling in chronic stable heart failure: a cardiovascular magnetic resonance study. Heart 90(7):760–764PubMedCrossRef Bellenger NG, Rajappan K, Rahman SL et al (2004) Effects of carvedilol on left ventricular remodelling in chronic stable heart failure: a cardiovascular magnetic resonance study. Heart 90(7):760–764PubMedCrossRef
2.
Zurück zum Zitat Klem I, Shah DJ, White RD et al (2011) Prognostic value of routine cardiac magnetic resonance assessment of left ventricular ejection fraction and myocardial damage: an international, multicenter study. Circ Cardiovasc Imaging 4(6):610–619PubMedCrossRef Klem I, Shah DJ, White RD et al (2011) Prognostic value of routine cardiac magnetic resonance assessment of left ventricular ejection fraction and myocardial damage: an international, multicenter study. Circ Cardiovasc Imaging 4(6):610–619PubMedCrossRef
3.
Zurück zum Zitat Miszalski-Jamka T, Klimeczek P, Tomala M et al (2010) Extent of RV dysfunction and myocardial infarction assessed by CMR are independent outcome predictors early after STEMI treated with primary angioplasty. JACC Cardiovasc Imaging 3(12):1237–1246PubMedCrossRef Miszalski-Jamka T, Klimeczek P, Tomala M et al (2010) Extent of RV dysfunction and myocardial infarction assessed by CMR are independent outcome predictors early after STEMI treated with primary angioplasty. JACC Cardiovasc Imaging 3(12):1237–1246PubMedCrossRef
4.
Zurück zum Zitat Jauhiainen T, Jarvinen VM, Hekali PE et al (1998) MR gradient echo volumetric analysis of human cardiac casts: focus on the right ventricle. J Comput Assist Tomogr 22(6):899–903PubMedCrossRef Jauhiainen T, Jarvinen VM, Hekali PE et al (1998) MR gradient echo volumetric analysis of human cardiac casts: focus on the right ventricle. J Comput Assist Tomogr 22(6):899–903PubMedCrossRef
5.
Zurück zum Zitat Bellenger NG, Davies LC, Francis JM et al (2000) Reduction in sample size for studies of remodeling in heart failure by the use of cardiovascular magnetic resonance. J Cardiovasc Magn Reson 2(4):271–278PubMedCrossRef Bellenger NG, Davies LC, Francis JM et al (2000) Reduction in sample size for studies of remodeling in heart failure by the use of cardiovascular magnetic resonance. J Cardiovasc Magn Reson 2(4):271–278PubMedCrossRef
6.
Zurück zum Zitat Pons-Llado G (2005) Assessment of cardiac function by CMR. Eur Radiol 15(Suppl 2):B23–B32PubMed Pons-Llado G (2005) Assessment of cardiac function by CMR. Eur Radiol 15(Suppl 2):B23–B32PubMed
7.
Zurück zum Zitat Sandstede J, Lipke C, Beer M et al (2000) Age- and gender-specific differences in left and right ventricular cardiac function and mass determined by cine magnetic resonance imaging. Eur Radiol 10(3):438–442PubMedCrossRef Sandstede J, Lipke C, Beer M et al (2000) Age- and gender-specific differences in left and right ventricular cardiac function and mass determined by cine magnetic resonance imaging. Eur Radiol 10(3):438–442PubMedCrossRef
8.
Zurück zum Zitat Natori S, Lai S, Finn JP et al (2006) Cardiovascular function in multi-ethnic study of atherosclerosis: normal values by age, sex, and ethnicity. AJR Am J Roentgenol 186(6 Suppl 2):S357–S365PubMedCrossRef Natori S, Lai S, Finn JP et al (2006) Cardiovascular function in multi-ethnic study of atherosclerosis: normal values by age, sex, and ethnicity. AJR Am J Roentgenol 186(6 Suppl 2):S357–S365PubMedCrossRef
9.
Zurück zum Zitat Alfakih K, Plein S, Bloomer T et al (2003) Comparison of right ventricular volume measurements between axial and short axis orientation using steady-state free precession magnetic resonance imaging. J Magn Reson Imaging 18(1):25–32PubMedCrossRef Alfakih K, Plein S, Bloomer T et al (2003) Comparison of right ventricular volume measurements between axial and short axis orientation using steady-state free precession magnetic resonance imaging. J Magn Reson Imaging 18(1):25–32PubMedCrossRef
10.
Zurück zum Zitat Kawut SM, Lima JA, Barr RG et al (2011) Sex and race differences in right ventricular structure and function: the multi-ethnic study of atherosclerosis-right ventricle study. Circulation 123(22):2542–2551PubMedCrossRef Kawut SM, Lima JA, Barr RG et al (2011) Sex and race differences in right ventricular structure and function: the multi-ethnic study of atherosclerosis-right ventricle study. Circulation 123(22):2542–2551PubMedCrossRef
11.
Zurück zum Zitat Janik M, Cham MD, Ross MI et al (2008) Effects of papillary muscles and trabeculae on left ventricular quantification: increased impact of methodological variability in patients with left ventricular hypertrophy. J Hypertens 26(8):1677–1685PubMedCrossRef Janik M, Cham MD, Ross MI et al (2008) Effects of papillary muscles and trabeculae on left ventricular quantification: increased impact of methodological variability in patients with left ventricular hypertrophy. J Hypertens 26(8):1677–1685PubMedCrossRef
12.
Zurück zum Zitat Alfakih K, Reid S, Jones T et al (2004) Assessment of ventricular function and mass by cardiac magnetic resonance imaging. Eur Radiol 14(10):1813–1822PubMedCrossRef Alfakih K, Reid S, Jones T et al (2004) Assessment of ventricular function and mass by cardiac magnetic resonance imaging. Eur Radiol 14(10):1813–1822PubMedCrossRef
13.
Zurück zum Zitat Maceira AM, Prasad SK, Khan M et al (2006) Reference right ventricular systolic and diastolic function normalized to age, gender and body surface area from steady-state free precession cardiovascular magnetic resonance. Eur Heart J 27(23):2879–2888PubMedCrossRef Maceira AM, Prasad SK, Khan M et al (2006) Reference right ventricular systolic and diastolic function normalized to age, gender and body surface area from steady-state free precession cardiovascular magnetic resonance. Eur Heart J 27(23):2879–2888PubMedCrossRef
14.
Zurück zum Zitat Alfakih K, Plein S, Thiele H et al (2003) Normal human left and right ventricular dimensions for MRI as assessed by turbo gradient echo and steady-state free precession imaging sequences. J Magn Reson Imaging 17(3):323–329PubMedCrossRef Alfakih K, Plein S, Thiele H et al (2003) Normal human left and right ventricular dimensions for MRI as assessed by turbo gradient echo and steady-state free precession imaging sequences. J Magn Reson Imaging 17(3):323–329PubMedCrossRef
Metadaten
Titel
Assessment of left and right ventricular parameters in healthy Korean volunteers using cardiac magnetic resonance imaging: change in ventricular volume and function based on age, gender and body surface area
verfasst von
Sung-A Chang
Yeon Hyeon Choe
Shin Yi Jang
Sung Mok Kim
Sang-Chol Lee
Jae K. Oh
Publikationsdatum
01.12.2012
Verlag
Springer Netherlands
Erschienen in
The International Journal of Cardiovascular Imaging / Ausgabe Sonderheft 2/2012
Print ISSN: 1569-5794
Elektronische ISSN: 1875-8312
DOI
https://doi.org/10.1007/s10554-012-0150-1

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