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Prognostic value of dual-source multidetector computed tomography coronary angiography in patients with stent implantation

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Abstract

We aim to evaluate the prognostic value of dual-source 64-slice multidetector computed tomography (MDCT) in patients with coronary stents. The study included 173 patients [mean age 59.9 ± 10.1 years, 76.7 % male] with previous stent implantation who underwent MDCT for evaluation of CAD and stent patency. Coronary imaging was performed via dual-source MDCT scanner. Stented vessel segment was evaluated as patent without neointimal hyperplasia (NIH), nonobstructive NIH (<50 % luminal narrowing), or obstructive NIH (>50 % luminal narrowing). Patients were evaluated for major cardiovascular events (MACEs) to demonstrate association between stent patency and clinical outcome. MACEs that were originating from non-stented segments were excluded. A total of 213 coronary stents were evaluated in our study. During mean of 21.2 ± 13.6 months’ follow-up, 25 patients experienced MACEs [1 (4.0 %) cardiac death, 5 (20.0 %) nonfatal MI, and 19 (76.0 %) unstable angina pectoris requiring hospitalization and target vessel revascularization] associated with stented segment of coronary arteries. One hundred of 105 patients (95.2 %) with a patent stent without NIH detected by MDCT had no cardiac event associated with stented segments during mean 2 years’ follow-up period. These data indicate that patients with a patent stent without NIH as determined by MDCT have a good prognosis as opposed to an increased rate of events among patients with either nonobstructive or obstructive NIH as determined with MDCT, supporting MDCT as a reliable tool to evaluate patients after coronary stenting.

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Acknowledgments

The authors would like to acknowledge and thank Mr Hakan Cakir, for their expert statistical advice during the revision phase of the current manuscript.

Conflict of interest

None.

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Authors and Affiliations

  1. Department of Cardiology, Ministry of Health Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey

    Hamza Sunman

  2. Department of Cardiology, Hacettepe University Faculty of Medicine, Sıhhiye, 06100, Ankara, Turkey

    Hikmet Yorgun, Muhammet Dural, Levent Şahiner, Ergün Barış Kaya, Kudret Aytemir, Lale Tokgözoğlu, Giray Kabakçı & Ali Oto

  3. Department of Cardiology, Türkiye Yüksek İhtisas Hospital, Ankara, Turkey

    Uğur Canpolat

  4. Kayseri Research and Education Hospital, Kayseri, Turkey

    Ayşegül Ülgen Kunak

  5. Department of Radiology, Hacettepe University Faculty of Medicine, Sihhiye, 06100, Ankara, Turkey

    Tuncay Hazırolan

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  1. Hamza Sunman
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  2. Hikmet Yorgun
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  3. Uğur Canpolat
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  10. Lale Tokgözoğlu
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  11. Giray Kabakçı
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  12. Ali Oto
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Correspondence to Hamza Sunman.

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Sunman, H., Yorgun, H., Canpolat, U. et al. Prognostic value of dual-source multidetector computed tomography coronary angiography in patients with stent implantation. Int J Cardiovasc Imaging 29, 1603–1611 (2013). https://doi.org/10.1007/s10554-013-0236-4

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  • DOI: https://doi.org/10.1007/s10554-013-0236-4

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