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Erschienen in: Cancer and Metastasis Reviews 4/2018

19.09.2018 | NON-THEMATIC REVIEW

A contemporary review of male breast cancer: current evidence and unanswered questions

verfasst von: Roberto A. Leon-Ferre, Karthik V. Giridhar, Tina J. Hieken, Robert W. Mutter, Fergus J. Couch, Rafael E. Jimenez, John R. Hawse, Judy C. Boughey, Kathryn J. Ruddy

Erschienen in: Cancer and Metastasis Reviews | Ausgabe 4/2018

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Abstract

Male breast cancer is rare, accounting for 1% of all breast cancer diagnoses in the USA. Because of its rarity, most major breast cancer trials have included only female patients. This has resulted in limited prospective data to guide the clinical management of men with breast cancer. As a result, treatment decisions are typically extrapolated from data generated in female patients. This approach may be suboptimal, particularly considering the differing hormonal milieus between men and women with respect to both breast cancer development and treatment. Herein, we summarize current knowledge of the biology and clinicopathology of male breast cancer and review current approaches to locoregional and systemic management of this rare disease.
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Metadaten
Titel
A contemporary review of male breast cancer: current evidence and unanswered questions
verfasst von
Roberto A. Leon-Ferre
Karthik V. Giridhar
Tina J. Hieken
Robert W. Mutter
Fergus J. Couch
Rafael E. Jimenez
John R. Hawse
Judy C. Boughey
Kathryn J. Ruddy
Publikationsdatum
19.09.2018
Verlag
Springer US
Erschienen in
Cancer and Metastasis Reviews / Ausgabe 4/2018
Print ISSN: 0167-7659
Elektronische ISSN: 1573-7233
DOI
https://doi.org/10.1007/s10555-018-9761-x

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