Skip to main content
Erschienen in: Digestive Diseases and Sciences 3/2007

01.03.2007 | Case Report

Diffuse Desmoplastic Metastatic Breast Cancer Simulating Cirrhosis with Severe Portal Hypertension: A Case of “Pseudocirrhosis”

verfasst von: David A. Sass, Kenneth Clark, Dana Grzybicki, Mordechai Rabinovitz, Thomas A. Shaw-Stiffel

Erschienen in: Digestive Diseases and Sciences | Ausgabe 3/2007

Einloggen, um Zugang zu erhalten

Excerpt

Hepatic metastases from breast cancer can occasionally mimic cirrhosis anatomically, in both the presence and the absence of prior systemic chemotherapy [13]. We present a case of diffuse desmoplastic metastatic breast carcinoma (Ca) masquerading as cirrhosis that presented with new-onset jaundice associated with severe portal hypertension and its sequelae. This case also serves as a background for a discussion of both the role of 18FDG-PET scanning in metastatic breast cancer and the entity of tamoxifen-induced hepatotoxicity. …
Literatur
1.
Zurück zum Zitat Young ST, Paulson EK, Washington K, Gulliver DJ, Vredenburgh JJ, Baker ME (1994) CT of the liver in patients with metastatic breast carcinoma treated by chemotherapy: findings simulating cirrhosis. AJR 163:1385–1388PubMed Young ST, Paulson EK, Washington K, Gulliver DJ, Vredenburgh JJ, Baker ME (1994) CT of the liver in patients with metastatic breast carcinoma treated by chemotherapy: findings simulating cirrhosis. AJR 163:1385–1388PubMed
2.
Zurück zum Zitat Nascimento AB, Mitchell DG, Rubin R, Weaver E (2001) Diffuse desmoplastic breast carcinoma metastases to the liver simulating cirrhosis at MR imaging: report of two cases. Radiology 221:117–121PubMed Nascimento AB, Mitchell DG, Rubin R, Weaver E (2001) Diffuse desmoplastic breast carcinoma metastases to the liver simulating cirrhosis at MR imaging: report of two cases. Radiology 221:117–121PubMed
3.
Zurück zum Zitat Shirkhoda A, Baird S (1994) Morphologic changes of the liver following chemotherapy for metastatic breast carcinoma: CT findings. Abdom Imaging 19:39–42PubMedCrossRef Shirkhoda A, Baird S (1994) Morphologic changes of the liver following chemotherapy for metastatic breast carcinoma: CT findings. Abdom Imaging 19:39–42PubMedCrossRef
4.
Zurück zum Zitat Fennessy FM, Mortele KJ, Kluckert T, Gogate A, Ondategui-Parra S, Ros P, Silverman SG (2004) Hepatic capsular retraction in metastatic carcinoma of the breast occurring with increase or decrease in size of subjacent metastasis. AJR 182:651–655PubMed Fennessy FM, Mortele KJ, Kluckert T, Gogate A, Ondategui-Parra S, Ros P, Silverman SG (2004) Hepatic capsular retraction in metastatic carcinoma of the breast occurring with increase or decrease in size of subjacent metastasis. AJR 182:651–655PubMed
5.
Zurück zum Zitat Moon DH, Maddahi J, Silverman DHS, Glaspy JA, Phelps ME, Hoh CK (1998) Accuracy of whole-body Fluorine-18-FDG PET for the detection of recurrent or metastatic breast carcinoma. J Nucl Med 39:431–435PubMed Moon DH, Maddahi J, Silverman DHS, Glaspy JA, Phelps ME, Hoh CK (1998) Accuracy of whole-body Fluorine-18-FDG PET for the detection of recurrent or metastatic breast carcinoma. J Nucl Med 39:431–435PubMed
6.
Zurück zum Zitat Smith IC, Welch AE, Hutcheon AW, Miller ID, Payne S, Chilcott F, Waikar S, Whitaker T, Ah-See AK, Eremin O, Heys SD, Gilbert FJ, Sharp PF (2000) Positron emission tomography using 18FDG to predict the pathologic response of breast cancer to primary chemotherapy. J Clin Oncol 18:1676–1688PubMed Smith IC, Welch AE, Hutcheon AW, Miller ID, Payne S, Chilcott F, Waikar S, Whitaker T, Ah-See AK, Eremin O, Heys SD, Gilbert FJ, Sharp PF (2000) Positron emission tomography using 18FDG to predict the pathologic response of breast cancer to primary chemotherapy. J Clin Oncol 18:1676–1688PubMed
7.
Zurück zum Zitat Schelling M, Avril N, Nahrig J, Kuhn W, Romer W, Sattler D, Werner M, Dose J, Janicke F, Graeff H, Schwaiger M (2000) Positron emission tomography using 18FDG for monitoring primary chemotherapy in breast cancer. J Clin Oncol 18:1689–1695PubMed Schelling M, Avril N, Nahrig J, Kuhn W, Romer W, Sattler D, Werner M, Dose J, Janicke F, Graeff H, Schwaiger M (2000) Positron emission tomography using 18FDG for monitoring primary chemotherapy in breast cancer. J Clin Oncol 18:1689–1695PubMed
8.
Zurück zum Zitat Loomus GN, Aneja P, Bota RA (1983) A case of peliosis hepatic in association with tamoxifen therapy. Am J Clin Pathol 80:881–883PubMed Loomus GN, Aneja P, Bota RA (1983) A case of peliosis hepatic in association with tamoxifen therapy. Am J Clin Pathol 80:881–883PubMed
9.
Zurück zum Zitat Moffat DF, Oien KA, Dickson J, et al. (2000) Hepatocellular carcinoma after long-term tamoxifen therapy. Ann Oncol 11:1195–1196PubMedCrossRef Moffat DF, Oien KA, Dickson J, et al. (2000) Hepatocellular carcinoma after long-term tamoxifen therapy. Ann Oncol 11:1195–1196PubMedCrossRef
10.
Zurück zum Zitat Pinto HC, Baptista A, Camilo ME, de Costa EB, Valente A, de Moura MC (1995) Tamoxifen-associated steatohepatitis—report of three cases. J Hepatol 23:95–97PubMedCrossRef Pinto HC, Baptista A, Camilo ME, de Costa EB, Valente A, de Moura MC (1995) Tamoxifen-associated steatohepatitis—report of three cases. J Hepatol 23:95–97PubMedCrossRef
11.
Zurück zum Zitat Storen EC, Hay JE, Kaur J, et al. (2000) Tamoxifen-induced submassive hepatic necrosis. Cancer J 6:58–60PubMed Storen EC, Hay JE, Kaur J, et al. (2000) Tamoxifen-induced submassive hepatic necrosis. Cancer J 6:58–60PubMed
12.
Zurück zum Zitat Oien KA, Moffat DF, Curry GW, Dickson J, Habeshaw T, Mills PR, MacSween RNM (1999) Cirrhosis with staetohepatitis after adjuvant tamoxifen. Lancet 353:36–37PubMedCrossRef Oien KA, Moffat DF, Curry GW, Dickson J, Habeshaw T, Mills PR, MacSween RNM (1999) Cirrhosis with staetohepatitis after adjuvant tamoxifen. Lancet 353:36–37PubMedCrossRef
Metadaten
Titel
Diffuse Desmoplastic Metastatic Breast Cancer Simulating Cirrhosis with Severe Portal Hypertension: A Case of “Pseudocirrhosis”
verfasst von
David A. Sass
Kenneth Clark
Dana Grzybicki
Mordechai Rabinovitz
Thomas A. Shaw-Stiffel
Publikationsdatum
01.03.2007
Erschienen in
Digestive Diseases and Sciences / Ausgabe 3/2007
Print ISSN: 0163-2116
Elektronische ISSN: 1573-2568
DOI
https://doi.org/10.1007/s10620-006-9332-9

Weitere Artikel der Ausgabe 3/2007

Digestive Diseases and Sciences 3/2007 Zur Ausgabe

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.