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Erschienen in: Digestive Diseases and Sciences 9/2008

01.09.2008 | Review

The Association Between Obesity and GERD: A Review of the Epidemiological Evidence

verfasst von: Hashem El-Serag

Erschienen in: Digestive Diseases and Sciences | Ausgabe 9/2008

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Abstract

The current epidemics of obesity and gastroesophageal reflux disease (GERD)-related disorders have generated much interest in studying the association between them. Results of multiple studies indicate that obesity satisfies several criteria for a causal association with GERD and some of its complications, including a generally consistent association with GERD symptoms, erosive esophagitis, and esophageal adenocarcinoma. An increase in GERD symptoms has been shown to occur in individuals who gain weight but continue to have a body mass index (BMI) in the normal range, contributing to the epidemiological evidence for a possible dose–response relationship between BMI and increasing GERD. Data are less clear on the relationship between Barrett’s esophagus (BE) and obesity. However, when considered separately, abdominal obesity seems to explain a considerable part of the association with GERD, including BE. Overall, epidemiological data show that maintaining a normal BMI may reduce the likelihood of developing GERD and its potential complications.
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Metadaten
Titel
The Association Between Obesity and GERD: A Review of the Epidemiological Evidence
verfasst von
Hashem El-Serag
Publikationsdatum
01.09.2008
Verlag
Springer US
Erschienen in
Digestive Diseases and Sciences / Ausgabe 9/2008
Print ISSN: 0163-2116
Elektronische ISSN: 1573-2568
DOI
https://doi.org/10.1007/s10620-008-0413-9

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