Severe Cholestasis and Renal Failure Associated with the Use of the Designer Steroid Superdrol™ (Methasteron™): A Case Report and Literature Review

Excerpt

The use of over the counter (OTC) nutritional supplements is widespread among amateur bodybuilders. Reports suggest that up to 30% of people who train regularly with weights use androgenic/anabolic steroids (AAS) and that a significant percentage of male high school students use AAS, not just for muscle gain but also to improve their physical appearance [1, 2]. The use of AAS is associated with a variety of potential liver injuries including toxic hepatitis and cholestasis [3, 4] but is often under-reported because of its clandestine use. Renal toxicity with the use of AAS has recently been demonstrated, which was thought to be related to IgA nephropathy [5]. We report a case of liver and renal injury secondary to a nutritional supplement called Superdrol™, with the anabolic steroid- methasteron™ as its active ingredient. …