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Erschienen in: Digestive Diseases and Sciences 9/2013

01.09.2013 | Original Article

Bilateral Metal Stents for Hilar Biliary Obstruction Using a 6Fr Delivery System: Outcomes Following Bilateral and Side-by-Side Stent Deployment

verfasst von: Ryan Law, Todd H. Baron

Erschienen in: Digestive Diseases and Sciences | Ausgabe 9/2013

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Abstract

Background and Study Aim

Controversy exists on optimal endoscopic management for palliation of malignant hilar obstruction, with advocates for metal “side-by-side” (SBS) and “stent-in-stent” (SIS) techniques. We sought to evaluate the technical feasibility, efficacy, and outcomes of bilateral biliary self-expanding metal stents (SEMS) for treatment of malignant hilar obstruction using a stent with a 6Fr delivery system.

Patients and Methods

This was a single-center, retrospective review of all patients who underwent bilateral placement of Zilver® biliary SEMS for malignant hilar obstruction from January 2010 to August 2012. Patients underwent endoscopic retrograde cholangiopancreatography with placement of stents using either the SIS or SBS stent techniques.

Results

Twenty-four patients (19 men, mean age 63 years) underwent bilateral stenting for malignant hilar obstruction during the study period. Seventeen and seven patients underwent the SBS and SIS technique, respectively. Cholangiocarcinoma (n = 14) was the most common cause of hilar obstruction. Initial technical success was achieved in 24/24 (100 %) of patients; however, 12 (50 %) patients required re-intervention during the study period (median 98 days). Comparison of the SBS and SIS groups revealed no statistical difference with respect to need for re-intervention (P = 0.31), successful re-intervention (P = 0.60), or procedural length (P = 0.89).

Conclusions

Use of bilateral Zilver® SEMS in either the SBS or SIS configuration is safe, technically feasible, and effective for drainage of malignant hilar obstruction; however, duration of stent patency and procedure-free survival remain variable.
Literatur
1.
Zurück zum Zitat Chahal P, Baron TH. Expandable metal stents for endoscopic bilateral stent-within-stent placement for malignant hilar biliary obstruction. Gastrointest Endosc. 2010;71:195–199.PubMedCrossRef Chahal P, Baron TH. Expandable metal stents for endoscopic bilateral stent-within-stent placement for malignant hilar biliary obstruction. Gastrointest Endosc. 2010;71:195–199.PubMedCrossRef
2.
Zurück zum Zitat Chennat J, Waxman I. Initial performance profile of a new 6F self-expanding metal stent for palliation of malignant hilar biliary obstruction. Gastrointest Endosc. 2010;72:632–636.PubMedCrossRef Chennat J, Waxman I. Initial performance profile of a new 6F self-expanding metal stent for palliation of malignant hilar biliary obstruction. Gastrointest Endosc. 2010;72:632–636.PubMedCrossRef
3.
Zurück zum Zitat De Palma GD, Galloro G, Siciliano S, et al. Unilateral versus bilateral endoscopic hepatic duct drainage in patients with malignant hilar biliary obstruction: results of a prospective, randomized, and controlled study. Gastrointest Endosc. 2001;53:547–553.PubMedCrossRef De Palma GD, Galloro G, Siciliano S, et al. Unilateral versus bilateral endoscopic hepatic duct drainage in patients with malignant hilar biliary obstruction: results of a prospective, randomized, and controlled study. Gastrointest Endosc. 2001;53:547–553.PubMedCrossRef
4.
Zurück zum Zitat Hwang JC, Kim JH, Lim SG, et al. Y-shaped endoscopic bilateral metal stent placement for malignant hilar biliary obstruction: prospective long-term study. Scand J Gastroenterol. 2011;46:326–332.PubMedCrossRef Hwang JC, Kim JH, Lim SG, et al. Y-shaped endoscopic bilateral metal stent placement for malignant hilar biliary obstruction: prospective long-term study. Scand J Gastroenterol. 2011;46:326–332.PubMedCrossRef
5.
Zurück zum Zitat Perdue DG, Freeman ML, DiSario JA, et al. Plastic versus self-expanding metallic stents for malignant hilar biliary obstruction: a prospective multicenter observational cohort study. J Clin Gastroenterol. 2008;42:1040–1046.PubMedCrossRef Perdue DG, Freeman ML, DiSario JA, et al. Plastic versus self-expanding metallic stents for malignant hilar biliary obstruction: a prospective multicenter observational cohort study. J Clin Gastroenterol. 2008;42:1040–1046.PubMedCrossRef
6.
Zurück zum Zitat Liberato MJ, Canena JM. Endoscopic stenting for hilar cholangiocarcinoma: efficacy of unilateral and bilateral placement of plastic and metal stents in a retrospective review of 480 patients. BMC Gastroenterol. 2012;12:103.PubMedCrossRef Liberato MJ, Canena JM. Endoscopic stenting for hilar cholangiocarcinoma: efficacy of unilateral and bilateral placement of plastic and metal stents in a retrospective review of 480 patients. BMC Gastroenterol. 2012;12:103.PubMedCrossRef
7.
Zurück zum Zitat Raju RP, Jaganmohan SR, Ross WA, et al. Optimum palliation of inoperable hilar cholangiocarcinoma: comparative assessment of the efficacy of plastic and self-expanding metal stents. Dig Dis Sci. 2011;56:1557–1564.PubMedCrossRef Raju RP, Jaganmohan SR, Ross WA, et al. Optimum palliation of inoperable hilar cholangiocarcinoma: comparative assessment of the efficacy of plastic and self-expanding metal stents. Dig Dis Sci. 2011;56:1557–1564.PubMedCrossRef
8.
Zurück zum Zitat Sangchan A, Kongkasame W, Pugkhem A, et al. Efficacy of metal and plastic stents in unresectable complex hilar cholangiocarcinoma: a randomized controlled trial. Gastrointest Endosc. 2012;76:93–99.PubMedCrossRef Sangchan A, Kongkasame W, Pugkhem A, et al. Efficacy of metal and plastic stents in unresectable complex hilar cholangiocarcinoma: a randomized controlled trial. Gastrointest Endosc. 2012;76:93–99.PubMedCrossRef
9.
Zurück zum Zitat Chang WH, Kortan P, Haber GB. Outcome in patients with bifurcation tumors who undergo unilateral versus bilateral hepatic duct drainage. Gastrointest Endosc. 1998;47:354–362.PubMedCrossRef Chang WH, Kortan P, Haber GB. Outcome in patients with bifurcation tumors who undergo unilateral versus bilateral hepatic duct drainage. Gastrointest Endosc. 1998;47:354–362.PubMedCrossRef
10.
Zurück zum Zitat Naitoh I, Ohara H, Nakazawa T, et al. Unilateral versus bilateral endoscopic metal stenting for malignant hilar biliary obstruction. J Gastroenterol Hepatol. 2009;24:552–557.PubMedCrossRef Naitoh I, Ohara H, Nakazawa T, et al. Unilateral versus bilateral endoscopic metal stenting for malignant hilar biliary obstruction. J Gastroenterol Hepatol. 2009;24:552–557.PubMedCrossRef
11.
Zurück zum Zitat Deviere J, Baize M, de Toeuf J, et al. Long-term follow-up of patients with hilar malignant stricture treated by endoscopic internal biliary drainage. Gastrointest Endosc. 1988;34:95–101.PubMedCrossRef Deviere J, Baize M, de Toeuf J, et al. Long-term follow-up of patients with hilar malignant stricture treated by endoscopic internal biliary drainage. Gastrointest Endosc. 1988;34:95–101.PubMedCrossRef
12.
Zurück zum Zitat Vienne A, Hobeika E, Gouya H, et al. Prediction of drainage effectiveness during endoscopic stenting of malignant hilar strictures: the role of liver volume assessment. Gastrointest Endosc. 2010;72:728–735.PubMedCrossRef Vienne A, Hobeika E, Gouya H, et al. Prediction of drainage effectiveness during endoscopic stenting of malignant hilar strictures: the role of liver volume assessment. Gastrointest Endosc. 2010;72:728–735.PubMedCrossRef
13.
Zurück zum Zitat Saleem A, Baron TH, Gostout CJ. Large-diameter therapeutic channel duodenoscope to facilitate simultaneous deployment of side-by-side self-expandable metal stents in hilar cholangiocarcinoma. Gastrointest Endosc. 2010;72:628–631.PubMedCrossRef Saleem A, Baron TH, Gostout CJ. Large-diameter therapeutic channel duodenoscope to facilitate simultaneous deployment of side-by-side self-expandable metal stents in hilar cholangiocarcinoma. Gastrointest Endosc. 2010;72:628–631.PubMedCrossRef
14.
Zurück zum Zitat Kim JY, Kang DH, Kim HW, et al. Usefulness of slimmer and open-cell-design stents for endoscopic bilateral stenting and endoscopic revision in patients with hilar cholangiocarcinoma (with video). Gastrointest Endosc. 2009;70:1109–1115.PubMedCrossRef Kim JY, Kang DH, Kim HW, et al. Usefulness of slimmer and open-cell-design stents for endoscopic bilateral stenting and endoscopic revision in patients with hilar cholangiocarcinoma (with video). Gastrointest Endosc. 2009;70:1109–1115.PubMedCrossRef
15.
Zurück zum Zitat Nguyen-Tang T, Dumonceau JM. A new method to facilitate bilateral hepatic duct drainage: simultaneous insertion of two thin 6-Fr self-expandable metal stents. Endoscopy. 2011;43:E24–E25.PubMedCrossRef Nguyen-Tang T, Dumonceau JM. A new method to facilitate bilateral hepatic duct drainage: simultaneous insertion of two thin 6-Fr self-expandable metal stents. Endoscopy. 2011;43:E24–E25.PubMedCrossRef
16.
Zurück zum Zitat Kim KM, Lee KH, Chung YH, et al. A comparison of bilateral stenting methods for malignant hilar biliary obstruction. Hepatogastroenterology. 2012;59:341–346.PubMed Kim KM, Lee KH, Chung YH, et al. A comparison of bilateral stenting methods for malignant hilar biliary obstruction. Hepatogastroenterology. 2012;59:341–346.PubMed
17.
Zurück zum Zitat Lee TH, Park DH, Lee SS, et al. Technical feasibility and revision efficacy of the sequential deployment of endoscopic bilateral side-by-side metal stents for malignant hilar biliary strictures: a multicenter prospective study. Dig Dis Sci. 2013;8:547–555. Lee TH, Park DH, Lee SS, et al. Technical feasibility and revision efficacy of the sequential deployment of endoscopic bilateral side-by-side metal stents for malignant hilar biliary strictures: a multicenter prospective study. Dig Dis Sci. 2013;8:547–555.
18.
Zurück zum Zitat Dumas R, Demuth N, Buckley M, et al. Endoscopic bilateral metal stent placement for malignant hilar stenoses: identification of optimal technique. Gastrointest Endosc. 2000;51:334–338.PubMedCrossRef Dumas R, Demuth N, Buckley M, et al. Endoscopic bilateral metal stent placement for malignant hilar stenoses: identification of optimal technique. Gastrointest Endosc. 2000;51:334–338.PubMedCrossRef
19.
Zurück zum Zitat Cheng JL, Bruno MJ, Bergman JJ, et al. Endoscopic palliation of patients with biliary obstruction caused by nonresectable hilar cholangiocarcinoma: efficacy of self-expandable metallic wallstents. Gastrointest Endosc. 2002;56:33–39.PubMedCrossRef Cheng JL, Bruno MJ, Bergman JJ, et al. Endoscopic palliation of patients with biliary obstruction caused by nonresectable hilar cholangiocarcinoma: efficacy of self-expandable metallic wallstents. Gastrointest Endosc. 2002;56:33–39.PubMedCrossRef
20.
Zurück zum Zitat Park do H, Lee SS, Moon JH, et al. Newly designed stent for endoscopic bilateral stent-in-stent placement of metallic stents in patients with malignant hilar biliary strictures: multicenter prospective feasibility study (with videos). Gastrointest Endosc. 2009;69:1357–1360.PubMedCrossRef Park do H, Lee SS, Moon JH, et al. Newly designed stent for endoscopic bilateral stent-in-stent placement of metallic stents in patients with malignant hilar biliary strictures: multicenter prospective feasibility study (with videos). Gastrointest Endosc. 2009;69:1357–1360.PubMedCrossRef
21.
Zurück zum Zitat Cotton PB, Eisen GM, Aabakken L, et al. A lexicon for endoscopic adverse events: report of an ASGE workshop. Gastrointest Endosc. 2010;71:446–454.PubMedCrossRef Cotton PB, Eisen GM, Aabakken L, et al. A lexicon for endoscopic adverse events: report of an ASGE workshop. Gastrointest Endosc. 2010;71:446–454.PubMedCrossRef
22.
Zurück zum Zitat Naitoh I, Hayashi K, Nakazawa T, et al. Side-by-side versus stent-in-stent deployment in bilateral endoscopic metal stenting for malignant hilar biliary obstruction. Dig Dis Sci. 2012;57:3279–3285. Naitoh I, Hayashi K, Nakazawa T, et al. Side-by-side versus stent-in-stent deployment in bilateral endoscopic metal stenting for malignant hilar biliary obstruction. Dig Dis Sci. 2012;57:3279–3285.
23.
Zurück zum Zitat Wagner HJ, Knyrim K, Vakil N, et al. Plastic endoprostheses versus metal stents in the palliative treatment of malignant hilar biliary obstruction. A prospective and randomized trial. Endoscopy. 1993;25:213–218.PubMedCrossRef Wagner HJ, Knyrim K, Vakil N, et al. Plastic endoprostheses versus metal stents in the palliative treatment of malignant hilar biliary obstruction. A prospective and randomized trial. Endoscopy. 1993;25:213–218.PubMedCrossRef
24.
Zurück zum Zitat Peters RA, Williams SG, Lombard M, et al. The management of high-grade hilar strictures by endoscopic insertion of self-expanding metal endoprostheses. Endoscopy. 1997;29:10–16.PubMedCrossRef Peters RA, Williams SG, Lombard M, et al. The management of high-grade hilar strictures by endoscopic insertion of self-expanding metal endoprostheses. Endoscopy. 1997;29:10–16.PubMedCrossRef
25.
Zurück zum Zitat Kim DU, Kang DH, Kim GH, et al. Bilateral biliary drainage for malignant hilar obstruction using the “stent-in-stent” method with a Y-stent: efficacy and complications. Eur J Gastroentero Hepatol. 2013;25:99–106 Kim DU, Kang DH, Kim GH, et al. Bilateral biliary drainage for malignant hilar obstruction using the “stent-in-stent” method with a Y-stent: efficacy and complications. Eur J Gastroentero Hepatol. 2013;25:99–106
26.
Zurück zum Zitat Lee TH, Moon JH, Kim JH, et al. Primary and revision efficacy of cross-wired metallic stents for endoscopic bilateral stent-in-stent placement in malignant hilar biliary strictures. Endoscopy. 2013;45:106–13. Lee TH, Moon JH, Kim JH, et al. Primary and revision efficacy of cross-wired metallic stents for endoscopic bilateral stent-in-stent placement in malignant hilar biliary strictures. Endoscopy. 2013;45:106–13.
Metadaten
Titel
Bilateral Metal Stents for Hilar Biliary Obstruction Using a 6Fr Delivery System: Outcomes Following Bilateral and Side-by-Side Stent Deployment
verfasst von
Ryan Law
Todd H. Baron
Publikationsdatum
01.09.2013
Verlag
Springer US
Erschienen in
Digestive Diseases and Sciences / Ausgabe 9/2013
Print ISSN: 0163-2116
Elektronische ISSN: 1573-2568
DOI
https://doi.org/10.1007/s10620-013-2671-4

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