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Erschienen in: Digestive Diseases and Sciences 1/2016

01.01.2016 | Review

Helicobacter Pylori Infection: Diagnostic Strategies in Primary Diagnosis and After Therapy

verfasst von: Nathan S. S. Atkinson, Barbara Braden

Erschienen in: Digestive Diseases and Sciences | Ausgabe 1/2016

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Abstract

Accurate diagnosis of Helicobacter pylori infection pre- and post-treatment is mandatory in the current era of decreasing prevalence and increasing antibiotic resistance. The diagnostic performance of most tests is poorer in clinical situations with low bacterial density which is seen in conditions such as atrophic gastritis or intake of antisecretory and antibiotic medications. Noninvasive tests require less cost and resource but provide excellent accuracy; however, endoscopy with testing of gastric biopsy specimens is indicated where alarming symptoms are present or antibiotic susceptibility testing by culture is desired. Newer modalities such as polymerase chain reaction testing provide additional virulence and antibiotic sensitivity profiling. This article outlines new developments and the key parameters of each test, as careful selection of test modality within the clinical context is required for adequate management of infected symptomatic patients.
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Metadaten
Titel
Helicobacter Pylori Infection: Diagnostic Strategies in Primary Diagnosis and After Therapy
verfasst von
Nathan S. S. Atkinson
Barbara Braden
Publikationsdatum
01.01.2016
Verlag
Springer US
Erschienen in
Digestive Diseases and Sciences / Ausgabe 1/2016
Print ISSN: 0163-2116
Elektronische ISSN: 1573-2568
DOI
https://doi.org/10.1007/s10620-015-3877-4

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