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Erschienen in:
30.06.2017 | Original Article
Evaluation of the International Consensus Guidelines for the Surgical Resection of Intraductal Papillary Mucinous Neoplasms
Erschienen in: Digestive Diseases and Sciences | Ausgabe 4/2018
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Background
International consensus guidelines for intraductal papillary mucinous neoplasms (IPMNs) were revised in 2012.
Aims
We aimed to evaluate the clinical utility of each predictor in the 2006 and 2012 guidelines and validate the diagnostic value and surgical indications.
Methods
Forty-two patients with surgically resected IPMNs were included. Each predictor was applied to evaluate its diagnostic value.
Results
The 2012 guidelines had greater accuracy for invasive carcinoma than the 2006 guidelines (64.3 vs. 31.0%). Moreover, the accuracy for high-grade dysplasia was also increased (48.6 vs. 77.1%). When the main pancreatic duct (MPD) size ≥8 mm was substituted for MPD size ≥10 mm in the 2012 guidelines, the accuracy for high-grade dysplasia was 80.0%.
Conclusions
The 2012 guidelines exhibited increased diagnostic accuracy for invasive IPMN. It is important to consider surgical resection prior to invasive carcinoma, and high-risk stigmata might be a useful diagnostic criterion. Furthermore, MPD size ≥8 mm may be predictive of high-grade dysplasia.