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Erschienen in: European Journal of Epidemiology 7/2007

01.07.2007 | Gastro-intestinal disease

Psychosocial factors at work and in every day life are associated with irritable bowel syndrome

verfasst von: Åshild Faresjö, Ewa Grodzinsky, Saga Johansson, Mari-Ann Wallander, Toomas Timpka, Ingemar Åkerlind

Erschienen in: European Journal of Epidemiology | Ausgabe 7/2007

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Abstract

The etiology of irritable bowel syndrome (IBS) tends to be complex and multi-factorial and there is still a lack of understanding of how different psychosocial factors are associated with the syndrome. Our aim was to examine the occurrence of psychosocial and behavioural factors among patients diagnosed with IBS in primary care. The study had an epidemiological population-based case–control design comparing 347 IBS cases to 1041 age and sex matched controls from the general population. A survey was directed to cases and controls based on validated questions asking for mood status, job strain, family history of IBS, and sleeping habits as well as education, nutritional and exercise habits and medication. In multivariate analyses, independent associations were found between IBS and lack of influence on work planning, a family history of IBS, anxiety, and sleeping disturbances. Important factors associated with IBS diagnosis among females were anxiety as well as family history of IBS and lack of co-determination at work. For males, only lack of influence on working pace and family history of IBS remained independently associated with an IBS diagnosis. The causal associations of the complex risk factor panorama for IBS warrants further study. This study indicates that there should be a special focus on investigating the psychosocial working conditions and their associations to IBS.
Literatur
1.
Zurück zum Zitat Thompson WG, Longstreth GF, Drossman DA, Heaton KW, Irvine EJ, Muller-Lissner SA. Functional bowel disorders and functional abdominal pain. Gut 1999; 45 Suppl 2:1143–7. Thompson WG, Longstreth GF, Drossman DA, Heaton KW, Irvine EJ, Muller-Lissner SA. Functional bowel disorders and functional abdominal pain. Gut 1999; 45 Suppl 2:1143–7.
2.
Zurück zum Zitat Talley NJ, Spiller R. Irritable bowel syndrome: a little understood organic bowel disease? Lancet 2002;360:555–64.PubMedCrossRef Talley NJ, Spiller R. Irritable bowel syndrome: a little understood organic bowel disease? Lancet 2002;360:555–64.PubMedCrossRef
3.
Zurück zum Zitat Jones R, Lydeard S. Irritable bowel syndrome in the general population. BMJ 1992;304:87–90.PubMedCrossRef Jones R, Lydeard S. Irritable bowel syndrome in the general population. BMJ 1992;304:87–90.PubMedCrossRef
4.
Zurück zum Zitat Thompsson WG, Heaton KW, Smyth GT, Smyth C. Irritable bowel syndrome in general practice: prevalence, characteristics and referral. Gut 2000;46:78–82.CrossRef Thompsson WG, Heaton KW, Smyth GT, Smyth C. Irritable bowel syndrome in general practice: prevalence, characteristics and referral. Gut 2000;46:78–82.CrossRef
5.
Zurück zum Zitat Longstreth GF, Wolde-Tsadik G. Irritable bowel-type symptoms in HMO examinees: prevalence, demographics, and clinical correlates. Dig Dis Sci 1993;38:1581–9.PubMedCrossRef Longstreth GF, Wolde-Tsadik G. Irritable bowel-type symptoms in HMO examinees: prevalence, demographics, and clinical correlates. Dig Dis Sci 1993;38:1581–9.PubMedCrossRef
6.
Zurück zum Zitat Zuckerman MJ, Guerra LG, Drossman DA, Foland JA, Gregory GG. Comparison of bowel patterns in Hispanics and non Hispanics whites. Dig Dis Sci 1995;40:1763–9.PubMedCrossRef Zuckerman MJ, Guerra LG, Drossman DA, Foland JA, Gregory GG. Comparison of bowel patterns in Hispanics and non Hispanics whites. Dig Dis Sci 1995;40:1763–9.PubMedCrossRef
7.
Zurück zum Zitat Saito YA, Schoenfeld P, Locke GR 3rd. The epidemiology of irritable bowel syndrome in North America; a systematic review. Am J Gastroenterol 2002;97:1910–5.PubMed Saito YA, Schoenfeld P, Locke GR 3rd. The epidemiology of irritable bowel syndrome in North America; a systematic review. Am J Gastroenterol 2002;97:1910–5.PubMed
8.
Zurück zum Zitat Faresjö Å, Grodzinsky E, Johansson S., Wallander M-A, Foldevi M. Patients with irritable bowel syndrome in Swedish primary care. Eur J Gen Pract 2006;12:88–90.PubMedCrossRef Faresjö Å, Grodzinsky E, Johansson S., Wallander M-A, Foldevi M. Patients with irritable bowel syndrome in Swedish primary care. Eur J Gen Pract 2006;12:88–90.PubMedCrossRef
9.
Zurück zum Zitat Corney RH, Stanton R. Physical symptom severity, psychological and social dysfunction in a series of outpatients with irritable bowel syndrome. Psychosom Res 1990;34:483–91.CrossRef Corney RH, Stanton R. Physical symptom severity, psychological and social dysfunction in a series of outpatients with irritable bowel syndrome. Psychosom Res 1990;34:483–91.CrossRef
10.
Zurück zum Zitat Saito VA, Petersen GM, Locke GR 3rd, Talley NJ. The genetics of irritable bowel syndrome. Clin Gastroenterol Hepatol 2005;3(11):1057–65.PubMedCrossRef Saito VA, Petersen GM, Locke GR 3rd, Talley NJ. The genetics of irritable bowel syndrome. Clin Gastroenterol Hepatol 2005;3(11):1057–65.PubMedCrossRef
11.
Zurück zum Zitat Munakata J, Naliboff B, Harraf F, Kodner A, Lembo T, Chang L, Silverman DH, Mayer EA. Repetitive sigmoid stimulation induces rectal hyperalgesia in patients with irritable bowel syndrome. Gastroenterology 1997;112:55–63.PubMedCrossRef Munakata J, Naliboff B, Harraf F, Kodner A, Lembo T, Chang L, Silverman DH, Mayer EA. Repetitive sigmoid stimulation induces rectal hyperalgesia in patients with irritable bowel syndrome. Gastroenterology 1997;112:55–63.PubMedCrossRef
12.
Zurück zum Zitat Drossman DA, Mckee DC, Sandler RS, Mitchell CM, Cramer EM, Lowman BC, Burger AL. Psychological factors in the irritable bowel syndrome. A multivariate study of patients and nonpatients with irritable bowel syndrome. Gastroenterology 1988;95:701–8.PubMed Drossman DA, Mckee DC, Sandler RS, Mitchell CM, Cramer EM, Lowman BC, Burger AL. Psychological factors in the irritable bowel syndrome. A multivariate study of patients and nonpatients with irritable bowel syndrome. Gastroenterology 1988;95:701–8.PubMed
13.
Zurück zum Zitat Lydiard RB. Irritable bowel syndrome, anxiety and depression: what are the links? J Clin Psychiatry 2001;62 Suppl 8:38–44.PubMed Lydiard RB. Irritable bowel syndrome, anxiety and depression: what are the links? J Clin Psychiatry 2001;62 Suppl 8:38–44.PubMed
14.
Zurück zum Zitat Faresjö Å, Grodzinsky E, Johansson S, Wallander MA, Timpka T, Åkerlind I. A population based case–control study of work and psychosocial problems in patients with irritable bowel syndrome-women are more seriously affected than men. Am J Gastroenterol 2007;102(2):371–9.PubMedCrossRef Faresjö Å, Grodzinsky E, Johansson S, Wallander MA, Timpka T, Åkerlind I. A population based case–control study of work and psychosocial problems in patients with irritable bowel syndrome-women are more seriously affected than men. Am J Gastroenterol 2007;102(2):371–9.PubMedCrossRef
15.
Zurück zum Zitat Karazek RA. Job demands, job decisions latitude, and mental strain: implications for job redesign. Adm Sci Q 1979;24:285–308.CrossRef Karazek RA. Job demands, job decisions latitude, and mental strain: implications for job redesign. Adm Sci Q 1979;24:285–308.CrossRef
16.
Zurück zum Zitat Johnson JV, Hall EM, Theorell T. Combined effect of job strain and social isolation and cardiovascular disease morbidity and mortality in a random sample of the Swedish male working population. Scand J Work Environ Health 1989;15:271–9.PubMed Johnson JV, Hall EM, Theorell T. Combined effect of job strain and social isolation and cardiovascular disease morbidity and mortality in a random sample of the Swedish male working population. Scand J Work Environ Health 1989;15:271–9.PubMed
17.
Zurück zum Zitat Schnall PL, Pieper C, Schwartz JE, Karazek RA, Schlussel Y, Devereux RB, Ganau A, Alderman M, Warren K, Pickering TG. The relationship between ‘job strain’, workplace diastolic blood pressure, and left ventricular mass index. Results of a case–control study. JAMA 1990;263(14):1929–35.PubMedCrossRef Schnall PL, Pieper C, Schwartz JE, Karazek RA, Schlussel Y, Devereux RB, Ganau A, Alderman M, Warren K, Pickering TG. The relationship between ‘job strain’, workplace diastolic blood pressure, and left ventricular mass index. Results of a case–control study. JAMA 1990;263(14):1929–35.PubMedCrossRef
18.
Zurück zum Zitat Hammar N, Alfredsson L, Theorell T. Job characteristics and the incidence of Myocardial infarction. Int J Epidemiol 1994;23(29):277–84.PubMedCrossRef Hammar N, Alfredsson L, Theorell T. Job characteristics and the incidence of Myocardial infarction. Int J Epidemiol 1994;23(29):277–84.PubMedCrossRef
19.
Zurück zum Zitat Collins SM, Karasek RA, Costas K. Job strain and autonomic indices of cardiovascular disease risk. Am J Ind Med 2005;48:182–93.PubMedCrossRef Collins SM, Karasek RA, Costas K. Job strain and autonomic indices of cardiovascular disease risk. Am J Ind Med 2005;48:182–93.PubMedCrossRef
20.
Zurück zum Zitat Whorwell PJ, McCallum M, Creed FH, Roberts CT, et al. Noncolonic features of irritable bowel syndrome. Gut 1986;27:37–40.PubMed Whorwell PJ, McCallum M, Creed FH, Roberts CT, et al. Noncolonic features of irritable bowel syndrome. Gut 1986;27:37–40.PubMed
21.
Zurück zum Zitat Bellentani S, Baldoni P, Petrella S, Tata C, Armociada C, Marchegiano P, Saccoccio G, Manenti F. A simple score for the identification of patients at high risk organic diseases of the colon in the family doctor consulting room: the local IBS study Group. Fam Pract 1990;7:307–12.PubMedCrossRef Bellentani S, Baldoni P, Petrella S, Tata C, Armociada C, Marchegiano P, Saccoccio G, Manenti F. A simple score for the identification of patients at high risk organic diseases of the colon in the family doctor consulting room: the local IBS study Group. Fam Pract 1990;7:307–12.PubMedCrossRef
22.
Zurück zum Zitat Locke GR 3rd, Zinsmeister AR, Talley NJ, Fett LS, Melton LJ 3rd. Familial association in adults with functional gastrointestinal disorders. Mayo Clin Proc 2000;75:907–12.PubMed Locke GR 3rd, Zinsmeister AR, Talley NJ, Fett LS, Melton LJ 3rd. Familial association in adults with functional gastrointestinal disorders. Mayo Clin Proc 2000;75:907–12.PubMed
23.
Zurück zum Zitat Kalantar JS, Locke GR III, Zinsmeister AR, Beighley CM, Talley NJ. Familial aggregation of irritable bowel syndrome: a prospective study. Gut 2003;52:1703–7.PubMedCrossRef Kalantar JS, Locke GR III, Zinsmeister AR, Beighley CM, Talley NJ. Familial aggregation of irritable bowel syndrome: a prospective study. Gut 2003;52:1703–7.PubMedCrossRef
24.
Zurück zum Zitat Morris-Yates A, Talley NJ, Boyce PM, Nandurkar S, Andrews G. Evidence of genetic contributions to functional bowel disorder. Am J Gasteoenterol 1998;93:1311–7.CrossRef Morris-Yates A, Talley NJ, Boyce PM, Nandurkar S, Andrews G. Evidence of genetic contributions to functional bowel disorder. Am J Gasteoenterol 1998;93:1311–7.CrossRef
25.
Zurück zum Zitat Levy RL, Jones RK, Whitehead WE, Feld SI, Talley NJ, Corey LA. Irritable bowel syndrome in twins: heredity and social learning both contribute to etiology. Gastroenterology 2001;121:799–804.PubMedCrossRef Levy RL, Jones RK, Whitehead WE, Feld SI, Talley NJ, Corey LA. Irritable bowel syndrome in twins: heredity and social learning both contribute to etiology. Gastroenterology 2001;121:799–804.PubMedCrossRef
26.
Zurück zum Zitat Faresjö Å, Grodzinsky E, Foldevi M, Johansson S, Wallander MA. IBS patients appear not to be heavy utilisers of primary health care. Aliment Pharmacol Ther 2006;23(6):807–14.PubMedCrossRef Faresjö Å, Grodzinsky E, Foldevi M, Johansson S, Wallander MA. IBS patients appear not to be heavy utilisers of primary health care. Aliment Pharmacol Ther 2006;23(6):807–14.PubMedCrossRef
27.
Zurück zum Zitat Herrman C. International experiences with the hospital anxiety and depression scale—a review of validation data and clinical results. J Psychosom Res 1997;42(1):17–41.CrossRef Herrman C. International experiences with the hospital anxiety and depression scale—a review of validation data and clinical results. J Psychosom Res 1997;42(1):17–41.CrossRef
28.
Zurück zum Zitat Statistics-Sweden. Employment, working hours and work environment 1994–95. Sveriges Officiella Statistik. Stockholm: Statistiska Centralbyrån (SCB), 1998. (In Swedish). Statistics-Sweden. Employment, working hours and work environment 1994–95. Sveriges Officiella Statistik. Stockholm: Statistiska Centralbyrån (SCB), 1998. (In Swedish).
29.
Zurück zum Zitat Karasek R, Theorell T. Healthy work, stress, productivity, and the reconstruction of working life. New York: Basic Books Inc. Publishers, 1990. Karasek R, Theorell T. Healthy work, stress, productivity, and the reconstruction of working life. New York: Basic Books Inc. Publishers, 1990.
30.
Zurück zum Zitat Kanazawa M, Endo Y, Whitehead WE, Kano M, Hongo M, Fukudo S. Patients and nonconsulters with irritable bowel syndrome reporting a parental history of bowel problems have more impaired psychological distress. Dig Dis Sci 2004;49(6):1046–53.PubMedCrossRef Kanazawa M, Endo Y, Whitehead WE, Kano M, Hongo M, Fukudo S. Patients and nonconsulters with irritable bowel syndrome reporting a parental history of bowel problems have more impaired psychological distress. Dig Dis Sci 2004;49(6):1046–53.PubMedCrossRef
31.
Zurück zum Zitat Toner BB, Garfinkel PE, Jeejeebhoy KN. Psychological factors in irritable bowel syndrome. Can J Psychiatry 1990;35:158–61.PubMed Toner BB, Garfinkel PE, Jeejeebhoy KN. Psychological factors in irritable bowel syndrome. Can J Psychiatry 1990;35:158–61.PubMed
32.
Zurück zum Zitat Lydiard RB, Fossey MD, Marsh W, Ballenger JC. Prevalence of psychiatric disorders in patients with irritable bowel syndrome. Psychosomatics 1993;34:229–34.PubMed Lydiard RB, Fossey MD, Marsh W, Ballenger JC. Prevalence of psychiatric disorders in patients with irritable bowel syndrome. Psychosomatics 1993;34:229–34.PubMed
33.
Zurück zum Zitat Payne S. Sex, gender, and irritable bowel syndrome making the connections. Gend Med 2004;1(1):18–28.PubMedCrossRef Payne S. Sex, gender, and irritable bowel syndrome making the connections. Gend Med 2004;1(1):18–28.PubMedCrossRef
34.
Zurück zum Zitat Drossman DA, Leserman J, Nachman G, Li ZM, Gluck H, Toomey TC, Mitchell CM. Sexual and physical abuse in women with functional or organic gastrointestinal disorders. Ann Intern Med 1990;113(11):828–33.PubMed Drossman DA, Leserman J, Nachman G, Li ZM, Gluck H, Toomey TC, Mitchell CM. Sexual and physical abuse in women with functional or organic gastrointestinal disorders. Ann Intern Med 1990;113(11):828–33.PubMed
35.
Zurück zum Zitat Walker EA, Roy-Byrne PP, Katon WJ, Li L, Amos D, Jiranek G. Psychiatric illness and irritable bowel syndrome: a comparison with inflammatory bowel disease. Am J Psychiatry 1990;147:1656–61.PubMed Walker EA, Roy-Byrne PP, Katon WJ, Li L, Amos D, Jiranek G. Psychiatric illness and irritable bowel syndrome: a comparison with inflammatory bowel disease. Am J Psychiatry 1990;147:1656–61.PubMed
36.
Zurück zum Zitat Stam R, Akkermans LM, Wiegant VM. Trauma and the gut: interactions between stressful experience and intestinal function. Gut 1997;40(6):704–9.PubMedCrossRef Stam R, Akkermans LM, Wiegant VM. Trauma and the gut: interactions between stressful experience and intestinal function. Gut 1997;40(6):704–9.PubMedCrossRef
37.
Zurück zum Zitat Heitkemper M, Ckarman Deitz AB, Shaver J, Lentz MJ, Jarett ME. Self-report and popysomnographic measures of sleep in women with irritable bowel syndrome. Nurs Res 1998;47(5):270–7.PubMedCrossRef Heitkemper M, Ckarman Deitz AB, Shaver J, Lentz MJ, Jarett ME. Self-report and popysomnographic measures of sleep in women with irritable bowel syndrome. Nurs Res 1998;47(5):270–7.PubMedCrossRef
38.
Zurück zum Zitat Jarett M, Heitkemper M, Cain KC, Burr R, Hertig V. Sleep disturbance influences gastrointestinal symptoms in women with irritable bowel syndrome. Dig Dis Sci 2000;45:952–9.CrossRef Jarett M, Heitkemper M, Cain KC, Burr R, Hertig V. Sleep disturbance influences gastrointestinal symptoms in women with irritable bowel syndrome. Dig Dis Sci 2000;45:952–9.CrossRef
39.
Zurück zum Zitat Elsenbruch S, Thompson JJ, Hamish MJ, Exton MS, Orr WC. Behavioural and physiological sleep characteristics in women with irritable bowel syndrome. Am J Gastroenterol 2002;97(9):2306–14.PubMedCrossRef Elsenbruch S, Thompson JJ, Hamish MJ, Exton MS, Orr WC. Behavioural and physiological sleep characteristics in women with irritable bowel syndrome. Am J Gastroenterol 2002;97(9):2306–14.PubMedCrossRef
40.
Zurück zum Zitat Gwee KA, Leong YL, Graham C, McKendrik MW, Collins SM, Walters SJ, Underwood JE, Read NW. The role of psychological and biological factors in post-infective gut dysfunction. Gut 1999;44:400–6.PubMedCrossRef Gwee KA, Leong YL, Graham C, McKendrik MW, Collins SM, Walters SJ, Underwood JE, Read NW. The role of psychological and biological factors in post-infective gut dysfunction. Gut 1999;44:400–6.PubMedCrossRef
41.
Zurück zum Zitat McKendrick MW, Read NW. Irritable bowel syndrome-post salmonella infection. J Infect 1994;29:1–3.PubMedCrossRef McKendrick MW, Read NW. Irritable bowel syndrome-post salmonella infection. J Infect 1994;29:1–3.PubMedCrossRef
42.
Zurück zum Zitat Neal KR, Hebden J, Spiller R. Prevalence of gastrointestinal symptoms six months after bacterial gastroenteritis and risk factors for development of the irritable bowel syndrome: postal survey of patients. BMJ 1997;314:779–82.PubMed Neal KR, Hebden J, Spiller R. Prevalence of gastrointestinal symptoms six months after bacterial gastroenteritis and risk factors for development of the irritable bowel syndrome: postal survey of patients. BMJ 1997;314:779–82.PubMed
43.
Zurück zum Zitat Garcia RLA, Ruigómez A. Increased risk of irritable bowel syndrome after bacterial gastroenteritis: cohort study. BMJ 1999;318:565–6. Garcia RLA, Ruigómez A. Increased risk of irritable bowel syndrome after bacterial gastroenteritis: cohort study. BMJ 1999;318:565–6.
44.
Zurück zum Zitat Talley NJ. When to conduct testing in patients with suspected irritable bowel syndrome. Rev Gastroenterol Disord 2003;3 Suppl 3:18–24. Talley NJ. When to conduct testing in patients with suspected irritable bowel syndrome. Rev Gastroenterol Disord 2003;3 Suppl 3:18–24.
45.
Zurück zum Zitat Agrèus L. Rome? Manning? Who cares? Am J Gastroenterol 2000;95(10):2679–81.PubMed Agrèus L. Rome? Manning? Who cares? Am J Gastroenterol 2000;95(10):2679–81.PubMed
46.
Zurück zum Zitat Bellini M, Tosetti C, Costa F, Biagi S, Stasi C, Del Punta A, Monicelli P, Mumolo MG, Ricchiuti A, Bruzzi P, Marchi S. The general practitioner’s approach to irritable bowel syndrome: from intention to practice. Dig Liver Dis 2005;37:934–9.PubMedCrossRef Bellini M, Tosetti C, Costa F, Biagi S, Stasi C, Del Punta A, Monicelli P, Mumolo MG, Ricchiuti A, Bruzzi P, Marchi S. The general practitioner’s approach to irritable bowel syndrome: from intention to practice. Dig Liver Dis 2005;37:934–9.PubMedCrossRef
47.
Zurück zum Zitat Mackenzie SG, Lippman A. An investigation of report bias in a case–control study of pregnancy outcome. Am J Epidemiol 1989;129:65–75.PubMed Mackenzie SG, Lippman A. An investigation of report bias in a case–control study of pregnancy outcome. Am J Epidemiol 1989;129:65–75.PubMed
Metadaten
Titel
Psychosocial factors at work and in every day life are associated with irritable bowel syndrome
verfasst von
Åshild Faresjö
Ewa Grodzinsky
Saga Johansson
Mari-Ann Wallander
Toomas Timpka
Ingemar Åkerlind
Publikationsdatum
01.07.2007
Verlag
Springer Netherlands
Erschienen in
European Journal of Epidemiology / Ausgabe 7/2007
Print ISSN: 0393-2990
Elektronische ISSN: 1573-7284
DOI
https://doi.org/10.1007/s10654-007-9133-2

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