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European Journal of Epidemiology

Erschienen in:

01.11.2015 | COMMENTARY

Some options in studying side effects of drugs taken during pregnancy

verfasst von: Jørn Olsen

Erschienen in: European Journal of Epidemiology | Ausgabe 11/2015

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Excerpt

Since the days of the thalidomide disaster [1], research on side effects of drugs taken during pregnancy has focused on congenital abnormalities (CA) or malformations (CM) and to a large extent at the expense of other possible end points of interest in studies of potential side effects of drugs. Drugs taken during pregnancy may in this time period lead to a variety of reproduction failures and perhaps also to health effects that will manifest themselves much later. ‘Fetal programming’ induced by medication taken before or during pregnancy is a research topic that deserves more attention. Diethylstilbestrol (DES) exposure leading to a transgenerational increased cancer risk [2, 3] represents such an example of research. …

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Titel: Some options in studying side effects of drugs taken during pregnancy
verfasst von: Jørn Olsen
Publikationsdatum: 01.11.2015
Verlag: Springer Netherlands
Erschienen in: European Journal of Epidemiology / Ausgabe 11/2015
Print ISSN: 0393-2990
Elektronische ISSN: 1573-7284
DOI: https://doi.org/10.1007/s10654-015-0110-x

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