Introduction
Methods
Data sources
Study population
Identification of prognostic factors for severe COVID-19
Analysis
Sensitivity analyses
Patient involvement
Results
Characteristics | N (%) |
---|---|
Total | 9,624,428 (100.0) |
Female | 4,814,553 (50.0) |
Age (years) | |
1–9 | 1,041,469 (10.8) |
10–19 | 1,046,237 (10.9) |
20–29 | 1,306,883 (13.6) |
30–39 | 1,203,053 (12.5) |
40–49 | 1,302,755 (13.5) |
50–59 | 1,220,303 (12.7) |
60–69 | 1,146,021 (11.9) |
70–79 | 856,218 (8.9) |
80+ | 501,489 (5.2) |
Mean age (years) (SD) | 41.4 (23.6) |
County | |
Stockholm | 2,174,039 (22.6) |
Uppsala | 346,325 (3.6) |
Södermanland | 277,220 (2.9) |
Östergötland | 436,474 (4.5) |
Jönköping | 339,444 (3.5) |
Kronoberg | 186,374 (1.9) |
Kalmar | 231,956 (2.4) |
Gotland | 56,639 (0.6) |
Blekinge | 152,136 (1.6) |
Skåne | 1,272,311 (13.2) |
Halland | 308,576 (3.2) |
Västra Götaland | 1,612,184 (16.8) |
Värmland | 270,128 (2.8) |
Örebro | 284,574 (3.0) |
Västmanland | 258,458 (2.7) |
Dalarna | 274,870 (2.9) |
Gävleborg | 275,551 (2.9) |
Västernorrland | 238,772 (2.5) |
Jämtland | 124,686 (1.3) |
Västerbotten | 258,371 (2.7) |
Norrbotten | 245,340 (2.5) |
Prognostic factors for severe COVID-19 | |
Age 70+ years | 1,357,707 (14.1) |
Cardiovascular disease | 708,090 (7.4) |
Cancer | 129,155 (1.3) |
COPD | 78,516 (0.8) |
Severe asthma | 215,793 (2.2) |
Diabetes | 471,015 (4.9) |
Number of prognostic factors for severe COVID-19 | |
At least one | 2,131,319 (22.1) |
At least two | 649,935 (6.8) |
At least three | 154,746 (1.6) |
Burden and prevalence of underlying medical conditions suggesting high risk severe COVID-19 by age group
Age (years) | Medical conditions, n (%) | ||||
---|---|---|---|---|---|
Cardiovascular disease | Cancer | COPD | Severe asthma | Diabetes | |
1–9 | 5241 (0.5) | 416 (0.0) | 652 (0.1) | 70,549 (6.8) | 1817 (0.2) |
10–19 | 8131 (0.8) | 298 (0.0) | 330 (0.0) | 39,110 (3.7) | 7192 (0.7) |
20–29 | 16,689 (1.3) | 1205 (0.1) | 266 (0.0) | 15,132 (1.2) | 13,264 (1.0) |
30–39 | 23,463 (2.0) | 3044 (0.3) | 371 (0.0) | 12,633 (1.1) | 18,407 (1.5) |
40–49 | 42,802 (3.3) | 7459 (0.6) | 1525 (0.1) | 15,266 (1.2) | 34,611 (2.7) |
50–59 | 77,250 (6.3) | 15,465 (1.3) | 6429 (0.5) | 16,281 (1.3) | 70,427 (5.8) |
60–69 | 148,688 (13.0) | 34,858 (3.0) | 18,923 (1.7) | 17,521 (1.5) | 121,901 (10.6) |
70–79 | 199,025 (23.2) | 40,649 (4.7) | 29,321 (3.4) | 16,794 (2.0) | 129,137 (15.1) |
80+ | 186,801 (37.2) | 25,761 (5.1) | 20,699 (4.1) | 12,507 (2.5) | 74,259 (14.8) |
Burden and prevalence of prognostic factors for severe COVID-19 by Swedish county
County | Prognostic factors, n (%) | |||||
---|---|---|---|---|---|---|
Age 70+ years | Cardiovascular disease | Cancer | COPD | Severe asthma | Diabetes | |
Stockholm | 242,208 (11.1) | 140,165 (6.4) | 27,234 (1.3) | 16,729 (0.8) | 56,251 (2.6) | 86,195 (4.0) |
Uppsala | 44,294 (12.8) | 22,086 (6.4) | 4328 (1.2) | 2615 (0.8) | 8193 (2.4) | 16,311 (4.7) |
Södermanland | 43,914 (15.8) | 20,608 (7.4) | 3470 (1.3) | 2923 (1.1) | 5861 (2.1) | 15,119 (5.5) |
Östergötland | 63,485 (14.5) | 32,390 (7.4) | 6228 (1.4) | 3766 (0.9) | 9807 (2.2) | 21,929 (5.0) |
Jönköping | 50,850 (15) | 26,994 (8.0) | 4738 (1.4) | 3295 (1.0) | 8121 (2.4) | 18,028 (5.3) |
Kronoberg | 28,654 (15.4) | 13,483 (7.2) | 2640 (1.4) | 1704 (0.9) | 4608 (2.5) | 9272 (5.0) |
Kalmar | 40,872 (17.6) | 20,270 (8.7) | 3570 (1.5) | 2448 (1.1) | 4782 (2.1) | 13,347 (5.8) |
Gotland | 9743 (17.2) | 4809 (8.5) | 892 (1.6) | 549 (1.0) | 1219 (2.2) | 3022 (5.3) |
Blekinge | 26,092 (17.2) | 12,389 (8.1) | 2358 (1.5) | 1435 (0.9) | 3257 (2.1) | 8080 (5.3) |
Skåne | 178,470 (14) | 98,919 (7.8) | 17,844 (1.4) | 11,791 (0.9) | 27,964 (2.2) | 64,259 (5.1) |
Halland | 47,199 (15.3) | 23,619 (7.7) | 5067 (1.6) | 2276 (0.7) | 7300 (2.4) | 13,653 (4.4) |
Västra Götaland | 221,567 (13.7) | 111,920 (6.9) | 21,510 (1.3) | 11,545 (0.7) | 29,353 (1.8) | 75,352 (4.7) |
Värmland | 45,646 (16.9) | 22,693 (8.4) | 3959 (1.5) | 2189 (0.8) | 6048 (2.2) | 16,784 (6.2) |
Örebro | 42,958 (15.1) | 20,344 (7.1) | 3563 (1.3) | 2039 (0.7) | 5243 (1.8) | 14,831 (5.2) |
Västmanland | 40,335 (15.6) | 21,114 (8.2) | 3596 (1.4) | 2244 (0.9) | 5446 (2.1) | 14,240 (5.5) |
Dalarna | 46,436 (16.9) | 24,205 (8.8) | 3533 (1.3) | 2133 (0.8) | 6512 (2.4) | 16,283 (5.9) |
Gävleborg | 45,805 (16.6) | 23,572 (8.6) | 3861 (1.4) | 2299 (0.8) | 6353 (2.3) | 16,031 (5.8) |
Västernorrland | 40,340 (16.9) | 19,492 (8.2) | 3159 (1.3) | 1694 (0.7) | 4764 (2.0) | 14,545 (6.1) |
Jämtland | 20,373 (16.3) | 8892 (7.1) | 1717 (1.4) | 1019 (0.8) | 2485 (2.0) | 7154 (5.7) |
Västerbotten | 38,120 (14.8) | 19,337 (7.5) | 3098 (1.2) | 1708 (0.6) | 5819 (2.3) | 12,675 (4.9) |
Norrbotten | 40,346 (16.4) | 20,789 (8.5) | 2790 (1.1) | 2115 (0.9) | 6407 (2.6) | 13,905 (5.7) |
Burden and prevalence of at least one, two, and three prognostic factors for severe COVID-19 by Swedish county
County | Prognostic factors, n (%) | ||
---|---|---|---|
At least one | At least two | At least three | |
Stockholm | 416,988 (19.2) | 119,057 (5.5) | 28,162 (1.3) |
Uppsala | 71,281 (20.6) | 20,674 (6) | 5046 (1.5) |
Södermanland | 66,330 (23.9) | 19,968 (7.2) | 4786 (1.7) |
Östergötland | 98,359 (22.5) | 30,431 (7.0) | 7480 (1.7) |
Jönköping | 78,639 (23.2) | 25,567 (7.5) | 6634 (2.0) |
Kronoberg | 43,911 (23.6) | 12,985 (7) | 3005 (1.6) |
Kalmar | 60,005 (25.9) | 19,699 (8.5) | 4839 (2.1) |
Gotland | 14,621 (25.8) | 4468 (7.9) | 1000 (1.8) |
Blekinge | 38,357 (25.2) | 11,947 (7.9) | 2832 (1.9) |
Skåne | 285,175 (22.4) | 89,187 (7.0) | 21,485 (1.7) |
Halland | 71,469 (23.2) | 21,780 (7.1) | 5062 (1.6) |
Västra Götaland | 341,102 (21.2) | 102,862 (6.4) | 23,704 (1.5) |
Värmland | 68,976 (25.5) | 22,231 (8.2) | 5350 (2.0) |
Örebro | 65,005 (22.8) | 19,142 (6.7) | 4288 (1.5) |
Västmanland | 61,821 (23.9) | 19,586 (7.6) | 4795 (1.9) |
Dalarna | 70,688 (25.7) | 22,431 (8.2) | 5238 (1.9) |
Gävleborg | 69,341 (25.2) | 22,299 (8.1) | 5448 (2.0) |
Västernorrland | 60,339 (25.3) | 18,841 (7.9) | 4266 (1.8) |
Jämtland | 29,989 (24.1) | 9175 (7.4) | 2147 (1.7) |
Västerbotten | 58,062 (22.5) | 17,906 (6.9) | 4184 (1.6) |
Norrbotten | 60,861 (24.8) | 19,699 (8.0) | 4995 (2.0) |