This study examined patterns of between-generation continuity in substance use from generation 1 (G1) parents to generation 2 (G2) adolescents and from G2 adult substance use and G1 substance use to generation 3 (G3) problem behavior in childhood. Structural equation modeling of prospective, longitudinal data from 808 participants, their parents, and their children showed low levels of G1 to G2 cross-generational continuity in the general tendency to use drugs. This effect was fully mediated by G2 early adolescent behavior problems. Drug-specific residual effects were observed across generations for cigarette smoking. Once established in adolescence, substance use in G2 showed stability over time. G2 substance use at age 27 significantly predicted G3 problem behavior. G1 substance use also was related to G3 problem behavior indirectly. These findings highlight the importance of interrupting intergenerational cycles of substance use and problem behavior.
Similar content being viewed by others
Notes
A portion of the sample was exposed to a multicomponent preventive intervention in the elementary grades, consisting of teacher training, parenting classes, and social competence training for children (Hawkins, Catalano, Kosterman, Abbott, & Hill, 1999). While differences in prevalences and means have been observed between intervention and control groups, prior analyses have shown few differences in the covariance structures of the groups (Catalano, Kosterman, Hawkins, Newcomb, & Abbott, 1996; Huang, Kosterman, Catalano, Hawkins, & Abbott, 2001). Similarly, analyses for this report were based on the full sample after examining possible differences in measurement and covariance structures between a group that received all of the intervention components and a control group of participants who received no intervention. Previous analyses have shown that this “full” intervention group was most likely to demonstrate significant intervention effects on mean levels of behavior (Hawkins et al., 1999). The control group was compared to the full intervention group using multiple group structural equation modeling. Nonsignificant results of the DIFFTEST procedure in Mplus (Muthén & Muthén, 1998-2004) support measurement invariance and invariance in structural parameters between the control and full intervention groups.
REFERENCES
Achenbach, T. M., & Edelbrock, C. (1986). Manual for the Teacher's Report Form and Teacher Version of the Child Behavior Profile. Burlington: University of Vermont Press.
Achenbach, T. M., & Rescorla, L. A. (2001). Manual for the ASEBA School-Age Forms & Profiles. Burlington: University of Vermont, Research Center for Children, Youth, & Families.
Andrews, J. A., Hops, H., & Duncan, S. C. (1997). Adolescent modeling of parent substance use: The moderating effect of the relationship with the parent. Journal of Family Psychology, 11, 259–270.
Aneshensel, C. S., & Sucoff, C. A. (1996). The neighborhood context of adolescent mental health. Journal of Health and Social Behavior, 37, 293–310.
Bachman, J. G., Wadsworth, K. N., O’Malley, P. M., Johnston, L. D., & Schulenberg, J. E. (1997). Smoking, drinking, and drug use in young adulthood: The impacts of new freedoms and new responsibilities. Mahwah, NJ: Lawrence Earlbaum Associates.
Barnard, M., & McKeganey, N. (2004). The impact of parental problem drug use on children: What is the problem and what can be done to help. Addiction, 99, 552–559.
Biederman, J., Petty, C., Faraone, S. V., Hirshfeld-Becker, D. R., Henin, A., Pollack, M. H., & Rosenbaum, J. F. (2005). Patterns of comorbidity in panic disorder and major depression: Findings from a nonreferred sample. Depression and Anxiety, 21, 55–60.
Bongers, I. L., Koot, H. M., van der Ende, J., & Verhulst, F. C. (2003). The normative development of child and adolescent problem behavior. Journal of Abnormal Psychology, 112, 179–192.
Brook, D. W., Richter, L., Whiteman, M., & Cohen, P. (1999). Consequences of adolescent marijuana use: Incompatibility with the assumption of adult roles. Genetic, Social, and General Psychology Monographs, 125, 193–203.
Brook, J. S., Tseng, L. J., & Cohen, P. (1996). Toddler adjustment: Impact of parents’ drug use, personality, and parent-child relations. The Journal of Genetic Psychology, 157, 281–295.
Brook, J. S., Whiteman, M., Finch, S., & Cohen, P. (1996). Young adult drug use and delinquency: Childhood antecedents and adolescent mediators. Journal of the American Academy of Child and Adolescent Psychiatry, 35, 1584–1592.
Brook, J. S., Whiteman, M., Shapiro, J., & Cohen, P. (1996). Effects of parent drug use and personality on toddler adjustment. The Journal of Genetic Psychology, 157, 19–35.
Browning, K., & Huizinga, D. (1999). Highlights of findings from the Denver Youth Survey (OJJDP Fact Sheet 106). Washington, D.C: Office of Juvenile Justice and Delinquency Prevention.
Capaldi, D. M., Pears, K. C., Patterson, G. R., & Owen, L. D. (2003). Continuity of parenting practices across generations in an at-risk sample: A prosepective comparison of direct and mediated associations. Journal of Abnormal Child Psychology, 31, 127–142.
Catalano, R. F., Haggerty, K. P., Gainey, R. R., & Hoppe, M. J. (1997). Reducing parental risk factors for children's substance misuse: Preliminary outcomes with opiate-addicted parents. Substance Use and Misuse, 32, 699–721.
Catalano, R. F., & Hawkins, J. D. (1996). The social development model: A theory of antisocial behavior. In J. D. Hawkins (Ed.), Delinquency and crime: Current theories (pp. 149–197). New York: Cambridge University Press.
Catalano, R. F., Kosterman, R., Hawkins, J. D., Newcomb, M. D., & Abbott, R. D. (1996). Modeling the etiology of adolescent substance use: A test of the social development model. Journal of Drug Issues, 26, 429–455.
Chassin, L., & Barrera, J. M. (1993). Substance use escalation and substance use restraint among adolescent children of alcoholics. Psychology of Addictive Behaviors, 7, 3–20.
Chassin, L., Pillow, D. R., Curran, P. J., Molina, B. S. G., & Barrera, J. M. (1993). Relation of parental alcoholism to early adolescent substance use: A test of three mediating mechanisms. Journal of Abnormal Psychology, 102, 3–19.
Chassin, L., Presson, C., Rose, J., Sherman, S. J., & Prost, J. (2002). Parental smoking cessation and adolescent smoking. Journal of Pediatric Psychology, 27, 485–495.
Chassin, L., Presson, C., Todd, M., Rose, J. S., & Sherman, S. J. (1998). Maternal socialization of adolescent smoking: The intergenerational transmission of parenting and smoking. Developmental Psychology, 34, 1189–1201.
Chassin, L., Rogosch, F., & Barrera, J. M. (1991). Substance use and symptomatology among adolescent children of alcoholics. Journal of Abnormal Psychology, 100, 449–463.
Clark, D. B., Moss, H. B., Kirisci, L., Mezzich, A., Miles, R., & Ott, P. (1997). Psychopathology in preadolescent sons of fathers with substance use disorders. Journal of the American Academy of Child and Adolescent Psychiatry, 36, 495–502.
Cohen, C., Kodas, E., & Griebel, G. (2005). CB1 receptor antagonists for the treatment of nicotine addiction. Pharmacology, Biochemistry and Behavior, 81, 387–395.
Colder, C. R., & Stice, E. (1998). A longitudinal study of the interactive effects of impulsivity and anger on adolescent problem behavior. Journal of Youth and Adolescence, 27, 255–274.
Collins, L. M., Schafer, J. L., & Kam, C. M. (2001). A comparison of inclusive and restrictive strategies in modern missing data procedures. Psychological Methods, 6, 330–351.
Conduct Problems Prevention Research Group. (2002a). Evaluation of the first three years of the Fast Track Prevention Trial with children at high risk for adolescent conduct problems. Journal of Abnormal Child Psychology, 30, 19–35.
Conduct Problems Prevention Research Group. (2002b). Implementation of the Fast Track Program: An example of a large-scale prevention science efficacy trial. Journal of Abnormal Child Psychology, 30, 1–17.
Conduct Problems Prevention Research Group. (2002c). Predictor variables associated with positive Fast Track outcomes at the end of the third grade. Journal of Abnormal Child Psychology, 30, 37–52.
Conger, R. D., Neppl, T., Kim, K. J., & Scaramella, L. (2003). Angry and aggressive behavior across three generations: A prospective, longitudinal study of parents and children. Journal of Abnormal Child Psychology, 31, 143–160.
Dishion, T. J., Patterson, G. R., Stoolmiller, M., & Skinner, M. L. (1991). Family, school, and behavioral antecedents to early adolescent involvement with antisocial peers. Developmental Psychology, 27, 172–180.
Elliott, D. S., & Huizinga, D. (1987). Scales from the National Youth Survey (38). Boulder, CO: University of Colorado/Institute of Behavioral Science.
Elliott, D. S., Huizinga, D., & Menard, S. (1989). Multiple problem youth: Delinquency, substance use, and mental health problems. New York: Springer-Verlag.
Esbensen, F. A., & Elliott, D. S. (1994). Continuity and discontinuity in illicit drug use: Patterns and antecedents. Journal of Drug Issues, 24, 75–97.
Fagot, B. I., Pears, K. C., Capaldi, D. M., Crosby, L., & Leve, C. (1998). Becoming an adolescent father: Precursors and parenting. Developmental Psychology, 34, 1209–1219.
Farrington, D. P., Jolliffe, D., Loeber, R., Stouthamer-Loeber, M., & Kalb, L. M. (2001). The concentration of offenders in families, and family criminality in the prediciton of boys’ delinquency. Journal of Adolescence, 24, 579–596.
Foshee, V., & Bauman, K. E. (1992). Parental and peer characteristics as modifiers of the bond-behavior relationship: An elaboration of control theory. Journal of Health and Social Behavior, 33, 66–76.
Frick, P. J., Christian, R. E., & Wootton, J. M. (1999). Age trends in the association between parenting practices and conduct problems. Behavior Modification, 23, 106–128.
Fuller, B. E., Chermack, S. T., Cruise, K. A., Kirsch, E., Fitzgerald, H. E., & Zucker, R. A. (2003). Predictors of aggression across three generations among sons of alcoholics: Relationships involving grandparental and parental alcoholism, child aggression, marital aggession, and parenting practices. Journal of Studies on Alcohol, 64, 472–483.
Graham, J. W., Cumsille, P. E., & Elek-Fisk, E. (2003). Methods for handling missing data. In J. A. Schinka & W. F. Velicer, (Eds.), Handbook of psychology: Research methods in psychology. Hoboken, NJ: John Wiley & Sons, Inc.
Greenwood, P., Model, K. E., Rydell, C. P., & Chiesa, J. (1996). Diverting children from a life of crime: Measuring costs and benefits ((MR-699.0-UCB/RC/IF)): Rand.
Han, C., McGue, M. K., & Iacono, W. G. (1999). Lifetime tobacco, alcohol and other substance use in adolescent Minnesota twins: Univariate and multivariate behavior genetic analyses. Addiction, 94, 981–993.
Hawkins, J. D., & Catalano, R. F. (unpublished survey). Social Development of Youth Project, Third and Ninth Grade Survey. Seattle, WA: Center for Law and Justice.
Hawkins, J. D., Catalano, R. F., Kosterman, R., Abbott, R., & Hill, K. G. (1999). Preventing adolescent health-risk behaviors by strengthening protection during childhood. Archives of Pediatrics and Adolescent Medicine, 153, 226–234.
Hawkins, J. D., Catalano, R. F., & Miller, J. Y. (1992). Risk and protective factors for alcohol and other drug problems in adolescence and early adulthood: Implications for substance-abuse prevention. Psychological Bulletin, 112, 64–105.
Hawkins, J. D., Graham, J. W., Maguin, E., Abbott, R., Hill, K. G., & Catalano, R. F. (1997). Exploring the effects of age of alcohol use initiation and psychosocial risk factors on subsequent alcohol misuse. Journal of Studies on Alcohol, 58, 280–290.
Hill, K. G., Hawkins, J. D., Catalano, R. F., Abbott, R. D., & Guo, J. (2005). Family influences on the risk of daily smoking initiation. Journal of Adolescent Health, 37, 202–210.
Hill, K. G., White, H. R., Chung, I. J., Hawkins, J. D., & Catalano, R. F. (2000). Early adult outcomes of adolescent binge drinking: Person- and variable-centered analyses of binge drinking trajectories. Alcoholism: Clinical and Experimental Research, 24, 892–901.
Hoffmann, J. P., & Cerbone, F. G. (2002). Parental substance use disorder and the risk of adolescent drug abuse: An event history analysis. Drug and Alcohol Dependence, 66, 255–264.
Hops, H., Davis, B., Leve, C., & Sheeber, L. (2003). Cross-generational transmission of aggressive parent behavior: A prospective, mediational examination. Journal of Abnormal Child Psychology, 31, 161–169.
Huang, B., Kosterman, R., Catalano, R. F., Hawkins, J. D., & Abbott, R. D. (2001). Modeling mediation in the etiology of violent behavior and adolescence: A test of the social development model. Criminology, 39, 75–107.
Iacono, W. G., Carlson, S. R., Taylor, J., Elkins, I. J., & McGue, M. (1999). Behavioral disinhibition and the development of substance-use disorders: Findings from the Minnesota Twin Family Study. Development and Psychology, 11, 869–900.
Jennison, K. M., & Johnson, K. A. (1998). Alcohol dependence in adult children of alcoholics: Longitudinal evidence of early risk. Journal of Drug Education, 28, 19–37.
Jessor, R., & Jessor, S. L. (1977). Problem behavior and psychological development: A longitudinal study of youth. New York: Academic Press.
Johnson, J. L., & Leff, M. (1999). Children of substance abusers: Overview of research findings. Pediatrics, 1085–1099.
Kandel, D. B. (1990). Parenting styles, drug use, and children's adjustment in families of young adults. Journal of Marriage and the Family, 52, 183–196.
Kandel, D. B., & Wu, P. (1995). The contributions of mothers and fathers to the intergenerational transmission of cigarette smoking in adolescence. Journal of Research on Adolescence, 5, 225–252.
Kendler, K. S., Jacobson, K. C., Prescott, C. A., & Neale, M. C. (2003). Specificity of genetic and environmental risk factors for use and abuse/dependence of cannabis, cocaine, hallucinogens, sedatives, stimulants, and opiates in male twins. American Journal of Psychiatry, 160, 687–695.
Kendler, K. S., Karkowski, L. M., Neale, M. C., & Prescott, C. A. (2000). Illicit psychoactive substance use, heavy use, abuse, and dependence in a US population-based sample of male twins. Archives of General Psychiatry, 57, 261–269.
Kendler, K. S., Prescott, C. A., Myers, J., & Neale, M. C. (2003). The structure of genetic and environmental risk factors for common psychiatric and substance use disorders in men and women. Archives of General Psychiatry, 30, 929–937.
Kessler, R. C., McGonagle, K. A., Zhao, S., Nelson, C. B., Hughes, M., Eshleman, S., Wittchen, H.-U., & Kendler, K. S. (1994). Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States: Results from the National Comorbidity Survey. Archives of General Psychiatry, 51, 8–19.
Kim-Cohen, J., Moffitt, T. E., Taylor, A., Pawlby, S. J., & Caspi, A. (2005). Maternal depression and children's antisocial behavior: Nature and nurture effects. Archives of General Psychiatry, 62, 173–181.
Kuperman, S., Schlosser, S. S., & Lidral, J. (1999). Relationship of child psychopathology to parental alcoholism and antisocial personality disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 38, 686–692.
Labouvie, E. (1996). Maturing out of substance use: Selection and self-correction. Journal of Drug Issues, 26, 457–476.
Leib, R., Merikangas, K. R., Hofler, M., Pfister, H., Isensee, B., & Wittchen, H.-U. (2002). Parental alcohol use disorders and alcohol use and disorders in offspring: A community study. Psychological Medicine, 32, 63–78.
Lengua, L. J., Sadowski, C. A., Friedrich, W. N., & Fisher, J. (2001). Rationally and empirically derived dimensions of children's symptomatology: Expert ratings and confirmatory factor analyses of the CBCL. Journal of Consulting and Clinical Psychology, 69, 683–698.
Leupker, R. V., & Leyasmeyer, E. (1999). Proceedings from the International Symposium on Primoridal Prevention of Cardiovascular Disease Risk Factors: Introduction. Preventive Medicine, 29, s1–s2.
Linnett, K. M., Dalsgaard, S., Obel, C., Wisborg, K., Henriksen, T. B., Rodriguez, A., Kotimaa, A., Moilanen, I., Thomsen, P. H., Olsen, J., & Jarvelin, M. R. (2003). Maternal lifestyle factors in pregnancy risk of Attention Deficit Hyperactivity Disorder and associated behaviors: Review of the current evidence. American Journal of Psychiatry, 160, 1028–1040.
Mansvelder, H. D., & McGehee, D. S. (2002). Cellular and synaptic mechanisms of nicotine addiction. Journal of Neurobiology, 53, 606–617.
Marmorstein, N. R., Malone, S. M., & Iacono, W. G. (2004). Psychiatric disorders among offspring of depressed mothers: Associations with paternal psychopathology. American Journal of Psychiatry, 161, 1588–1594.
McGue, M. (1994). Genes, environment, and the etiology of alcoholism. In R. A. Zucker, G. M. Boyd,& J. Howard (Eds.), The development of alcohol problems: Exploring the biopsychosocial matrix of risk. National Institute on Alcohol Abuse and Alcoholism Research Monograph 26 (pp. 1–40). Washington, DC: U.S. Department of Health and Human Services.
McGue, M., Elkins, I. J., & Iacono, W. G. (2000). Genetic and environmental influences on adolescent substance use and abuse. American Journal of Medical Genetics, 96, 671–677.
McGue, M., Iacono, W. G., Legrand, L. N., Malone, S., & Elkins, I. J. (2001). Origins and consequences of age at first drink I: Associations with substance-use disorders, disinhibitory behavior and psychopathology, and P3 amplitude. Alcoholism: Clinical and Experimental Research, 25, 1156–1165.
McGue, M., Sharma, A., & Benson, P. (1996). Parent and sibling influences on adolescent alcohol use and misuse: Evidence from a U.S. adoption cohort. Journal of Studies on Alcohol, 57, 8–18.
Menard, S., Mihalic, S., & Huizinga, D. (2001). Drugs and crime revisited. Justice Quarterly, 18, 269–299.
Merikangas, K. R., & Avenevoli, S. (2000). Implications of genetic epidemiology for the prevention of substance use disorders. Addictive Behaviors, 25, 807–820.
Merikangas, K. R., Dierker, L. C., & Szatmari, P. (1998). Psychopathology among offspring of parents with substance abuse and/or anxiety disorders: A high-risk study. Journal of Child Psychology and Psychiatry, 39, 711–720.
Merikangas, K. R., Stolar, M., Stevens, D. E., Goulet, J., Preisig, M. A., Fenton, B., Zhang, H., O’Malley, S. S., & Rounsaville, B. J. (1998). Familial transmission of substance use disorders. Archives of General Psychiatry, 55, 973–979.
Milberger, S., Biederman, J., Faraone, S. V., Chen, L., & Jones, J. (1996). Is maternal smoking during pregnancy a risk factor for Attention Deficit Hyperactivity Disorder in children? American Journal of Psychiatry, 153, 1138–1142.
Milberger, S., Biederman, J., Faraone, S. V., Chen, L., & Jones, J. (1997). ADHD is associated with early initiation of cigarette smoking in children and adolescents. Journal of the American Academy of Child and Adolescent Psychiatry, 36, 37–44.
Moss, H. B., Vanyukov, M., Yao, J. K., & Kirillova, G. P. (1999). Salivary cortisol responses in prepubertal boys: The effects of parental substance abuse and association with drug use behavior during adolescence. Biological Psychiatry, 45, 1293–1299.
Muthen, L. K., & Muthen, B. O. (2003a). Mplus short course day 1 handout: Traditional latent variable modeling using Mplus. Los Angeles, CA: Muthen & Muthen.
Muthen, L. K., & Muthen, B. O. (2003b). Mplus short course day 3 handout: Special topics in latent variable modeling using Mplus. Los Angeles, CA: Muthen & Muthen.
Muthén, L. K., & Muthén, B. O. (1998–2004). Mplus user's guide (3rd edn.). Los Angeles, CA: Muthén & Muthén.
Neumark-Sztainer, D., Story, M., French, S. A., & Resnick, M. (1997). Psychosocial correlates of health compromising behaviors among adolescents. Health Education Research: Theory and Practice, 12, 37–52.
Obot, I. S., Wagner, F. A., & Anthony, J. C. (2000). Early onset and recent drug use among children of parents with alcohol problems: Data from a national epidemiologic survey. Drug and Alcohol Dependence, 65, 1–8.
O’Donnell, J., Hawkins, J. D., & Abbott, R. D. (1995). Predicting serious delinquency and substance use among aggressive boys. Journal of Consulting and Clinical Psychology, 63, 529–537.
Pelham, W. E., & Lang, A. R. (1999). Can your children drive you to drink? Stress and parenting in adults interacting with children with ADHD. Alcohol Research and Health, 23, 292–298.
Pelham, W. E., Lang, A. R., Atkeson, B., Murphy, D. A., Gnagy, E. M., Greiner, A. R., Vodde-Hamilton, M., & Greenslade, K. E. (1997). Effects of deviant child behavior on parental distress and alcohol consumption in laboratory interactions. Journal of Abnormal Child Psychology, 25, 413–424.
Rhee, S. H., & Waldman, I. D. (2002). Genetic and environmental influences on antisocial behavior: A meta-analysis of twin and adoption studies. Psychological Bulletin, 128, 490–529.
Rohde, P., Lewinsohn, P. M., Kahler, C. W., Seeley, J. R., & Brown, R. A. (2001). Natural course of alcohol use disorders from adolescence to young adulthood. Journal of the American Academy of Child and Adolescent Psychiatry, 40, 83–90.
Schafer, J. L., & Graham, J. W. (2002). Missing data: Our view of the state of the art. Psychological Methods, 7, 147–177.
Stein, J. A., Newcomb, M. D., & Bentler, P. M. (1993). Differential effects of parent and grandparent drug use on behavior problems of male and female children. Developmental Psychology, 29, 31–43.
Tarter, R., Vanukov, M., Giancola, P., Dawes, M., Blackson, T., Mezzich, A., & Clark, D. B. (1999). Etiology of early age onset substance use disorder: A maturational perspective. Development and Psychopathology, 11, 657–683.
Thornberry, T. P., Freeman-Gallant, A., Lizotte, A. J., Krohn, M. D., & Smith, C. A. (2003). Linked lives: The intergenerational transmission of antisocial behavior. Journal of Abnormal Child Psychology, 31, 171–184.
Tsuang, M. T., Bar, J. L., Harley, R. M., & Lyons, M. J. (2001). The Harvard Twin Study of substance abuse: What we have learned. Harvard Review of Psychiatry, 9, 267–279.
Walters, G. D. (2002). The heritability of alcohol abuse and dependence: A meta-analysis of behavior genetic research. American Journal of Drug and Alcohol Abuse, 28, 557–584.
Webster-Stratton, C., Mihalic, S., Fagan, A., Arnold, D., Taylor, T., & Tingley, C. (2001). Blueprints for Violence Prevention, Book Eleven: The Incredible Years: Parent, teacher, and children training series. Boulder, CO: Center for the Study and Prevention of Violence.
Zilberman, M. L., Tavares, H., Blume, S. B., & el-Guebaly, N. (2003). Substance use disorders: Sex differences and psychiatric comorbidities. Canadian Journal of Psychiatry, 48, 5–15.
ACKNOWLEDGMENTS
This research was supported by research grants # 1RO1DA12138 and #R01DA09679 from the National Institute on Drug Abuse. Points of view are those of the authors and are not the official positions of the funding agency. Portions of the findings reported here were presented at the 12th Annual Meeting of the Society for Prevention Research, Quebec, Canada. Correspondence concerning this article and requests for reprints should be addressed to Jennifer Bailey, Social Development Research Group, 9725 3rd Avenue NE, Suite 401, Seattle, WA 98115 (fax) 206-543-4507 or jabailey@u.washington.edu. We gratefully acknowledge the SDRG data collection team, as well as Tanya Williams for her help in editing this manuscript.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Bailey, J.A., Hill, K.G., Oesterle, S. et al. Linking Substance Use and Problem Behavior Across Three Generations. J Abnorm Child Psychol 34, 263–282 (2006). https://doi.org/10.1007/s10802-006-9033-z
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10802-006-9033-z