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Self-assembly of nanohydroxyapatite in mesoporous silica

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Abstract

A novel material hexagonal mesoporous silica-hydroxyapatite (HMS-HA) has been developed based on self-assembly of nanohydroxyapatite in mesoporous silica in situ. The structural and textural properties of the materials are, respectively, characterized via X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), N2 adsorption, thermogravimetic analysis, and high-resolution transmission electron spectroscopy (HRTEM). Variable crystallinity of HA involved in the mesopores yields from different sintering temperature, and correspondingly determines different degradation manners. This biocompatible new material hybridized nanoporosity to well acknowledge biofunctional scaffold (HA). It promises a high potential for application in drug and gene delivery.

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Acknowledgments

This research was supported by the National Basic Research Program of China (Grant 2005CB623902), the National Natural Science Foundation of China (Grant 50572029), the Natural Science Foundation Team Project of Guangdong (Grant 4205786), and the Key Programs of the Ministry of Education (Grant 305012). And we thank Dr. Dong-An Wang at Nanyang Technological University (Singapore) for helpful revision.

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Authors and Affiliations

  1. School of Materials Science and Engineering, South China University of Technology, Guangzhou, 510641, China

    Xuetao Shi, Yingjun Wang, Kun Wei, Li Ren & Chen Lai

  2. Key Laboratory of Specially Functional Materials and Advanced Manufacturing Technology, South China University of Technology, Ministry of Education, Guangzhou, 510641, China

    Xuetao Shi, Yingjun Wang, Kun Wei, Li Ren & Chen Lai

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  1. Xuetao Shi
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  2. Yingjun Wang
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  3. Kun Wei
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  4. Li Ren
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Correspondence to Yingjun Wang.

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Shi, X., Wang, Y., Wei, K. et al. Self-assembly of nanohydroxyapatite in mesoporous silica. J Mater Sci: Mater Med 19, 2933–2940 (2008). https://doi.org/10.1007/s10856-008-3424-3

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  • DOI: https://doi.org/10.1007/s10856-008-3424-3

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