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Erschienen in: Journal of Behavioral Medicine 5/2009

01.10.2009

The relationship between neuropsychological functioning and HAART adherence in HIV-positive adults: a systematic review

verfasst von: Travis I. Lovejoy, Julie A. Suhr

Erschienen in: Journal of Behavioral Medicine | Ausgabe 5/2009

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Abstract

Combination antiretroviral therapy has helped extend the lives of persons infected with HIV; however, the efficacy of highly active antiretroviral therapy (HAART) regimens depends, in part, on the consistency with which the medications are taken. In this paper, we review 11 empirical studies conducted in Western developed nations that utilized psychometrically valid neuropsychological measures to examine the relationship between cognitive functioning and HAART adherence. In general, impaired neuropsychological functioning—particularly within the domains of executive functioning and problem solving, learning and memory, attention and working memory, and global cognitive functioning—was associated with lower medication adherence across studies. However, inconsistent operationalizations of neuropsychological impairment and medication adherence employed in these studies, as well as the paucity of longitudinal data to support temporal relationships, may attenuate these conclusions. We conclude with a set of research recommendations that may help to improve the rigor of future studies and clarify questions left unanswered due to methodological limitations of existing studies.
Literatur
Zurück zum Zitat Albert, S. M., Flater, S. R., Clouse, R., Todak, G., Stern, Y., & Marder, K. (2003). Medication management skill in HIV: I. Evidence for adaptation of medication management strategies in people with cognitive impairment. II. Evidence for a pervasive lay model of medication efficacy. AIDS and Behavior, 7, 329–338. doi:10.1023/A:1025404105378.PubMedCrossRef Albert, S. M., Flater, S. R., Clouse, R., Todak, G., Stern, Y., & Marder, K. (2003). Medication management skill in HIV: I. Evidence for adaptation of medication management strategies in people with cognitive impairment. II. Evidence for a pervasive lay model of medication efficacy. AIDS and Behavior, 7, 329–338. doi:10.​1023/​A:​1025404105378.PubMedCrossRef
Zurück zum Zitat Albert, S. M., Weber, C. M., Todak, G., Polanco, C., Clouse, R., McElhiney, M., et al. (1999). An observed performance test of medication management ability in HIV: Relation to neuropsychological status and medication adherence outcomes. AIDS and Behavior, 3, 121–128. doi:10.1023/A:1025483806464.CrossRef Albert, S. M., Weber, C. M., Todak, G., Polanco, C., Clouse, R., McElhiney, M., et al. (1999). An observed performance test of medication management ability in HIV: Relation to neuropsychological status and medication adherence outcomes. AIDS and Behavior, 3, 121–128. doi:10.​1023/​A:​1025483806464.CrossRef
Zurück zum Zitat Ammassari, A., Antinori, A., Aloisi, M. S., Trotta, M. P., Murri, R., Bartoli, L., et al. (2004). Depressive symptoms, neurocognitive impairment, and adherence to highly active antiretroviral therapy among HIV-infected patients. Psychosomatics, 45, 394–402. doi:10.1176/appi.psy.45.5.394.PubMedCrossRef Ammassari, A., Antinori, A., Aloisi, M. S., Trotta, M. P., Murri, R., Bartoli, L., et al. (2004). Depressive symptoms, neurocognitive impairment, and adherence to highly active antiretroviral therapy among HIV-infected patients. Psychosomatics, 45, 394–402. doi:10.​1176/​appi.​psy.​45.​5.​394.PubMedCrossRef
Zurück zum Zitat Ammassari, A., Trotta, M. P., Murri, R., Castelli, F., Narciso, P., Noto, P., et al. (2002). Correlates and predictors of adherence to highly active antiretroviral therapy: Overview of published literature. Journal of Acquired Immune Deficiency Syndromes, 31, S123–S127.PubMed Ammassari, A., Trotta, M. P., Murri, R., Castelli, F., Narciso, P., Noto, P., et al. (2002). Correlates and predictors of adherence to highly active antiretroviral therapy: Overview of published literature. Journal of Acquired Immune Deficiency Syndromes, 31, S123–S127.PubMed
Zurück zum Zitat Avants, S. K., Margolin, A., Warburton, L. A., Hawkins, K. A., & Shi, J. (2001). Predictors of nonadherence to HIV-related medication regimens during methadone stabilization. The American Journal on Addictions, 10, 69–78. doi:10.1080/105504901750160501.PubMedCrossRef Avants, S. K., Margolin, A., Warburton, L. A., Hawkins, K. A., & Shi, J. (2001). Predictors of nonadherence to HIV-related medication regimens during methadone stabilization. The American Journal on Addictions, 10, 69–78. doi:10.​1080/​1055049017501605​01.PubMedCrossRef
Zurück zum Zitat Bangsberg, D. R., Hecht, F. M., Charlebois, E. D., Zalopa, A. R., Holodniy, M., Sheiner, L., et al. (2000). Adherence to protease inhibitors, HIV-1 viral load, and development of drug resistance in an indigent population. AIDS (London, England), 14, 357–366. doi:10.1097/00002030-200003100-00008. Bangsberg, D. R., Hecht, F. M., Charlebois, E. D., Zalopa, A. R., Holodniy, M., Sheiner, L., et al. (2000). Adherence to protease inhibitors, HIV-1 viral load, and development of drug resistance in an indigent population. AIDS (London, England), 14, 357–366. doi:10.​1097/​00002030-200003100-00008.
Zurück zum Zitat Barclay, T. R., Hinkin, C. H., Castellon, S. A., Mason, K. I., Reinhard, M. J., Marion, S. D., et al. (2007). Age-associated predictors of medication adherence in HIV-positive adults: Health beliefs, self-efficacy, and neurocognitive status. Health Psychology, 26, 40–49. doi:10.1037/0278-6133.26.1.40.PubMedCrossRef Barclay, T. R., Hinkin, C. H., Castellon, S. A., Mason, K. I., Reinhard, M. J., Marion, S. D., et al. (2007). Age-associated predictors of medication adherence in HIV-positive adults: Health beliefs, self-efficacy, and neurocognitive status. Health Psychology, 26, 40–49. doi:10.​1037/​0278-6133.​26.​1.​40.PubMedCrossRef
Zurück zum Zitat Benton, A. L., Hamsher, K., & Sivan, A. B. (1983). Multilingual aphasia examination (3rd ed ed.). Iowa City, IA: AJA Associates. Benton, A. L., Hamsher, K., & Sivan, A. B. (1983). Multilingual aphasia examination (3rd ed ed.). Iowa City, IA: AJA Associates.
Zurück zum Zitat Brew, B. J. (2004). Evidence for a change in AIDS dementia complex in the era of highly active antiretroviral therapy and the possibility of new forms of AIDS dementia complex. AIDS (London, England), 18, S75–S78. doi:10.1097/00002030-200401001-00011. Brew, B. J. (2004). Evidence for a change in AIDS dementia complex in the era of highly active antiretroviral therapy and the possibility of new forms of AIDS dementia complex. AIDS (London, England), 18, S75–S78. doi:10.​1097/​00002030-200401001-00011.
Zurück zum Zitat Butters, N., Grant, I., Haxby, J., Judd, L. L., Martin, A., McClelland, J., et al. (1990). Assessment of AIDS-related cognitive changes: Recommendations of the NIMH workshop on neuropsychological assessment approaches. Journal of Clinical and Experimental Neuropsychology, 12, 963–978. doi:10.1080/01688639008401035.PubMedCrossRef Butters, N., Grant, I., Haxby, J., Judd, L. L., Martin, A., McClelland, J., et al. (1990). Assessment of AIDS-related cognitive changes: Recommendations of the NIMH workshop on neuropsychological assessment approaches. Journal of Clinical and Experimental Neuropsychology, 12, 963–978. doi:10.​1080/​0168863900840103​5.PubMedCrossRef
Zurück zum Zitat Casado, J. L., Sabido, R., Perez-Elias, M. J., Antela, A., Oliva, J., Dronda, F., et al. (1999). Percentage of adherence correlates with the risk of protease inhibitor (PI) treatment failure in HIV-infected patients. Antiviral Therapy, 4, 157–161.PubMed Casado, J. L., Sabido, R., Perez-Elias, M. J., Antela, A., Oliva, J., Dronda, F., et al. (1999). Percentage of adherence correlates with the risk of protease inhibitor (PI) treatment failure in HIV-infected patients. Antiviral Therapy, 4, 157–161.PubMed
Zurück zum Zitat Chesney, M. A., Ickovics, J. R., Chambers, D. B., Gifford, A. L., Neidig, J., Zwickl, B., et al. (2000). Self-reported adherence to antiretroviral medications among participants in HIV clinical trials: The AACTG adherence instruments. AIDS Care, 12, 255–266. doi:10.1080/09540120050042891.PubMedCrossRef Chesney, M. A., Ickovics, J. R., Chambers, D. B., Gifford, A. L., Neidig, J., Zwickl, B., et al. (2000). Self-reported adherence to antiretroviral medications among participants in HIV clinical trials: The AACTG adherence instruments. AIDS Care, 12, 255–266. doi:10.​1080/​0954012005004289​1.PubMedCrossRef
Zurück zum Zitat D’Elia, L., Satz, P., Uchiyama, C. L., & White, T. (1996). Color trails 1 and 2. Odessa, FL: Psychological Assessment Resources. D’Elia, L., Satz, P., Uchiyama, C. L., & White, T. (1996). Color trails 1 and 2. Odessa, FL: Psychological Assessment Resources.
Zurück zum Zitat Delis, D. C., Kramer, J. H., Kaplan, E., & Ober, B. A. (1987). CVLT adult version: California verbal learning test manual, version 1. San Antonio, TX: The Psychological Corporation, Harcourt Brace & Company. Delis, D. C., Kramer, J. H., Kaplan, E., & Ober, B. A. (1987). CVLT adult version: California verbal learning test manual, version 1. San Antonio, TX: The Psychological Corporation, Harcourt Brace & Company.
Zurück zum Zitat Falagas, M. E., Zarkadoulia, E. A., Pliatsika, P. A., & Panos, G. (2008). Socioeconomic status (SES) as a determinant of adherence to treatment in HIV infected patients: A systematic review of the literature. Retrovirology, 5, 13. doi:10.1186/1742-4690-5-13.PubMedCrossRef Falagas, M. E., Zarkadoulia, E. A., Pliatsika, P. A., & Panos, G. (2008). Socioeconomic status (SES) as a determinant of adherence to treatment in HIV infected patients: A systematic review of the literature. Retrovirology, 5, 13. doi:10.​1186/​1742-4690-5-13.PubMedCrossRef
Zurück zum Zitat Falutz, J. (2007). Therapy insight: Body-shape changes and metabolic complications associated with HIV and highly active antiretroviral therapy. Nature Clinical Practice. Endocrinology & Metabolism, 3, 651–661. doi:10.1038/ncpendmet0587.CrossRef Falutz, J. (2007). Therapy insight: Body-shape changes and metabolic complications associated with HIV and highly active antiretroviral therapy. Nature Clinical Practice. Endocrinology & Metabolism, 3, 651–661. doi:10.​1038/​ncpendmet0587.CrossRef
Zurück zum Zitat Flowers, K. A., & Robertson, C. (1985). The effects of Parkinson’s disease on the ability to maintain a mental set. Journal of Neurology, Neurosurgery, and Neuropsychiatry, 48, 517–529. doi:10.1136/jnnp.48.6.517.CrossRef Flowers, K. A., & Robertson, C. (1985). The effects of Parkinson’s disease on the ability to maintain a mental set. Journal of Neurology, Neurosurgery, and Neuropsychiatry, 48, 517–529. doi:10.​1136/​jnnp.​48.​6.​517.CrossRef
Zurück zum Zitat Fogarty, L., Roter, D., Larson, S., Burke, J., Gillespie, J., & Levy, R. (2002). Patient adherence to HIV medication regimens: A review of published and abstract reports. Patient Education and Counseling, 46, 93–108. doi:10.1016/S0738-3991(01)00219-1.PubMedCrossRef Fogarty, L., Roter, D., Larson, S., Burke, J., Gillespie, J., & Levy, R. (2002). Patient adherence to HIV medication regimens: A review of published and abstract reports. Patient Education and Counseling, 46, 93–108. doi:10.​1016/​S0738-3991(01)00219-1.PubMedCrossRef
Zurück zum Zitat Garcia de Olalla, P., Knobel, H., Carmona, A., Gnelar, A., Lopez-Colmes, J. L., & Cayla, J. A. (2002). Impact of adherence and highly active antiretroviral therapy on survival in HIV-infected patients. Journal of Acquired Immune Deficiency Syndrome, 23, 386–395. Garcia de Olalla, P., Knobel, H., Carmona, A., Gnelar, A., Lopez-Colmes, J. L., & Cayla, J. A. (2002). Impact of adherence and highly active antiretroviral therapy on survival in HIV-infected patients. Journal of Acquired Immune Deficiency Syndrome, 23, 386–395.
Zurück zum Zitat Grant, D. A., & Berg, E. A. (1948). A behavioral analysis of degree of reinforcement and ease of shifting to new responses in a Weigl-type card-sorting problem. Journal of Experimental Psychology, 38, 404–411. doi:10.1037/h0059831.PubMedCrossRef Grant, D. A., & Berg, E. A. (1948). A behavioral analysis of degree of reinforcement and ease of shifting to new responses in a Weigl-type card-sorting problem. Journal of Experimental Psychology, 38, 404–411. doi:10.​1037/​h0059831.PubMedCrossRef
Zurück zum Zitat Grober, E., & Sliwinski, M. (1991). A prospective study of predictors of adherence to combination antiretroviral medication. Journal of General Internal Medicine, 17, 756–765. Grober, E., & Sliwinski, M. (1991). A prospective study of predictors of adherence to combination antiretroviral medication. Journal of General Internal Medicine, 17, 756–765.
Zurück zum Zitat Heaton, R., Grant, I., & Matthews, C. (1991). Comprehensive norms for an expanded Halstead-Reitan battery: Demographic corrections, research findings, and clinical implications. Odessa, FL: Psychological Assessment Resources. Heaton, R., Grant, I., & Matthews, C. (1991). Comprehensive norms for an expanded Halstead-Reitan battery: Demographic corrections, research findings, and clinical implications. Odessa, FL: Psychological Assessment Resources.
Zurück zum Zitat Hinkin, C. H., Castellon, S. A., Durvasula, R. S., Hardy, D. J., Lam, M. N., Mason, K. I., et al. (2002). Medication adherence among HIV+ adults: Effects of cognitive dysfunction and regimen complexity. Neurology, 59, 1944–1950.PubMed Hinkin, C. H., Castellon, S. A., Durvasula, R. S., Hardy, D. J., Lam, M. N., Mason, K. I., et al. (2002). Medication adherence among HIV+ adults: Effects of cognitive dysfunction and regimen complexity. Neurology, 59, 1944–1950.PubMed
Zurück zum Zitat Hinkin, C. H., Hardy, D. J., Mason, K. I., Castellon, S. A., Durvasula, R. S., Lam, M. N., et al. (2004). Medication adherence in HIV-infected adults: Effects of patient age, cognitive status, and substance abuse. AIDS (London, England), 18, S19–S25. doi:10.1097/00002030-200401001-00004. Hinkin, C. H., Hardy, D. J., Mason, K. I., Castellon, S. A., Durvasula, R. S., Lam, M. N., et al. (2004). Medication adherence in HIV-infected adults: Effects of patient age, cognitive status, and substance abuse. AIDS (London, England), 18, S19–S25. doi:10.​1097/​00002030-200401001-00004.
Zurück zum Zitat Kalichman, S. C., Amaral, C. M., Stearns, H., White, D., Falnagan, J., Pope, H., et al. (2007). Adherence to antiretroviral therapy assessed by unannounced pill counts conducted by telephone. Journal of General Internal Medicine, 22, 1003–1006. doi:10.1007/s11606-007-0171-y.PubMedCrossRef Kalichman, S. C., Amaral, C. M., Stearns, H., White, D., Falnagan, J., Pope, H., et al. (2007). Adherence to antiretroviral therapy assessed by unannounced pill counts conducted by telephone. Journal of General Internal Medicine, 22, 1003–1006. doi:10.​1007/​s11606-007-0171-y.PubMedCrossRef
Zurück zum Zitat Kaufman, A. S., & Kaufman, N. L. (1993). Manual: KAIT Kaufman adolescent & adult intelligence test. Circle Pines, MN: American Guidance Service, Inc. Kaufman, A. S., & Kaufman, N. L. (1993). Manual: KAIT Kaufman adolescent & adult intelligence test. Circle Pines, MN: American Guidance Service, Inc.
Zurück zum Zitat Klove, H. (1963). Clinical neuropsychology. The Medical Clinics of North America, 46, 1647–1658. Klove, H. (1963). Clinical neuropsychology. The Medical Clinics of North America, 46, 1647–1658.
Zurück zum Zitat Levine, A. J., Hinkin, C. H., Castellon, S. A., Mason, K. I., Lam, M. N., Perkins, A., et al. (2005). Variations in patterns of highly active antiretroviral therapy (HAART) adherence. AIDS and Behavior, 9, 355–362. doi:10.1007/s10461-005-9009-y.PubMedCrossRef Levine, A. J., Hinkin, C. H., Castellon, S. A., Mason, K. I., Lam, M. N., Perkins, A., et al. (2005). Variations in patterns of highly active antiretroviral therapy (HAART) adherence. AIDS and Behavior, 9, 355–362. doi:10.​1007/​s10461-005-9009-y.PubMedCrossRef
Zurück zum Zitat Levine, A. J., Hinkin, C. H., Marion, S., Keuning, A., Castellon, S. A., Lam, M. N., et al. (2006). Adherence to antiretroviral medications in HIV: Differences in data collected via self-report and electronic monitoring. Health Psychology, 25, 329–335. doi:10.1037/0278-6133.25.3.329.PubMedCrossRef Levine, A. J., Hinkin, C. H., Marion, S., Keuning, A., Castellon, S. A., Lam, M. N., et al. (2006). Adherence to antiretroviral medications in HIV: Differences in data collected via self-report and electronic monitoring. Health Psychology, 25, 329–335. doi:10.​1037/​0278-6133.​25.​3.​329.PubMedCrossRef
Zurück zum Zitat Lezak, M. D., Howieson, D. B., & Loring, D. W. (2004). Neuropsychological assessment (4th ed.). New York: Oxford University Press. Lezak, M. D., Howieson, D. B., & Loring, D. W. (2004). Neuropsychological assessment (4th ed.). New York: Oxford University Press.
Zurück zum Zitat Maggiolo, F., Airoldi, M., Kleinloog, H. D., Callegaro, A., Ravasio, V., Arici, C., et al. (2007). Effect of adherence to HAART on virologic outcome and on the selection of resistance-conferring mutations in NNRTI- or PI-treated patients. HIV Clinical Trials, 8, 282–292. doi:10.1310/hct0805-282.PubMedCrossRef Maggiolo, F., Airoldi, M., Kleinloog, H. D., Callegaro, A., Ravasio, V., Arici, C., et al. (2007). Effect of adherence to HAART on virologic outcome and on the selection of resistance-conferring mutations in NNRTI- or PI-treated patients. HIV Clinical Trials, 8, 282–292. doi:10.​1310/​hct0805-282.PubMedCrossRef
Zurück zum Zitat Miller, E. N., Satz, P., & Visscher, B. (1991). Computerized and conventional neuropsychological assessment in HIV-1 infected homosexual men. Neurology, 41, 1608–1616.PubMed Miller, E. N., Satz, P., & Visscher, B. (1991). Computerized and conventional neuropsychological assessment in HIV-1 infected homosexual men. Neurology, 41, 1608–1616.PubMed
Zurück zum Zitat Murphy, E. L., Collier, A. C., Kalish, L. A., Assmann, S. F., Para, M. R., Flanigan, T. P., et al. (2001). Highly active antiretroviral therapy decreases mortality and morbidity in patients with advanced HIV disease. Annals of Internal Medicine, 135, 17–26.PubMed Murphy, E. L., Collier, A. C., Kalish, L. A., Assmann, S. F., Para, M. R., Flanigan, T. P., et al. (2001). Highly active antiretroviral therapy decreases mortality and morbidity in patients with advanced HIV disease. Annals of Internal Medicine, 135, 17–26.PubMed
Zurück zum Zitat Nicastri, E., Leone, S., Angeletti, C., Palmisano, L., Sarmati, L., Chiesi, A., et al. (2007). Sex issues in HIV-1-infected persons during highly active antiretroviral therapy: A systematic review. The Journal of Antimicrobial Chemotherapy, 60, 724–732. doi:10.1093/jac/dkm302.PubMedCrossRef Nicastri, E., Leone, S., Angeletti, C., Palmisano, L., Sarmati, L., Chiesi, A., et al. (2007). Sex issues in HIV-1-infected persons during highly active antiretroviral therapy: A systematic review. The Journal of Antimicrobial Chemotherapy, 60, 724–732. doi:10.​1093/​jac/​dkm302.PubMedCrossRef
Zurück zum Zitat Nieuwkerk, P. T., Sprangers, M. A. G., Burger, D. M., Hoetelmans, R. M. W., Hugen, P. W. H., Danner, S. A., et al. (2001). Limited patient adherence to highly active antiretroviral therapy for HIV-1 infection in an observational cohort study. Archives of Internal Medicine, 161, 1962–1968. doi:10.1001/archinte.161.16.1962.PubMedCrossRef Nieuwkerk, P. T., Sprangers, M. A. G., Burger, D. M., Hoetelmans, R. M. W., Hugen, P. W. H., Danner, S. A., et al. (2001). Limited patient adherence to highly active antiretroviral therapy for HIV-1 infection in an observational cohort study. Archives of Internal Medicine, 161, 1962–1968. doi:10.​1001/​archinte.​161.​16.​1962.PubMedCrossRef
Zurück zum Zitat Paterson, D. L., Swindells, S., Mohr, J., Brester, M., Vergis, E. N., Squier, C., et al. (2000). Adherence to protease inhibitor therapy and outcomes in patients with HIV infection. Annals of Internal Medicine, 133, 21–30.PubMed Paterson, D. L., Swindells, S., Mohr, J., Brester, M., Vergis, E. N., Squier, C., et al. (2000). Adherence to protease inhibitor therapy and outcomes in patients with HIV infection. Annals of Internal Medicine, 133, 21–30.PubMed
Zurück zum Zitat Rey, A. (1941). L’examen psychologique dans las cas d’encephalopathie traumatique. Archives de Psychologie, 28, 286–340. Rey, A. (1941). L’examen psychologique dans las cas d’encephalopathie traumatique. Archives de Psychologie, 28, 286–340.
Zurück zum Zitat Sacktor, N., McDermott, M. P., Marder, K., Schifitto, G., Selnes, O. A., McArthur, J. C., et al. (2002). HIV-associated cognitive impairment before and after the advent of combination therapy. Journal of Neurovirology, 8, 136–142. doi:10.1080/13550280290101094.PubMedCrossRef Sacktor, N., McDermott, M. P., Marder, K., Schifitto, G., Selnes, O. A., McArthur, J. C., et al. (2002). HIV-associated cognitive impairment before and after the advent of combination therapy. Journal of Neurovirology, 8, 136–142. doi:10.​1080/​1355028029010109​4.PubMedCrossRef
Zurück zum Zitat Santos, G., Puga, A. M., & Medina, C. (2004). HAART, adherence, and cultural issues in the US Latino community. The AIDS Reader, 14, S26–S29.PubMed Santos, G., Puga, A. M., & Medina, C. (2004). HAART, adherence, and cultural issues in the US Latino community. The AIDS Reader, 14, S26–S29.PubMed
Zurück zum Zitat Selnes, O. A., Jacobson, L., Machado, A. M., Becker, J. T., Wesch, J., Miller, E. N., et al. (1991). Normative data for a brief neuropsychological screening battery. Multicenter AIDS cohort study. Perceptual and Motor Skills, 73, 539–550. doi:10.2466/PMS.73.5.539-550.PubMedCrossRef Selnes, O. A., Jacobson, L., Machado, A. M., Becker, J. T., Wesch, J., Miller, E. N., et al. (1991). Normative data for a brief neuropsychological screening battery. Multicenter AIDS cohort study. Perceptual and Motor Skills, 73, 539–550. doi:10.​2466/​PMS.​73.​5.​539-550.PubMedCrossRef
Zurück zum Zitat Sidtis, J. J., Gatsonis, C., Price, R. W., Singer, E. J., Collier, A. C., Richman, D. D., et al. (1993). Zidovudine treatment of the AIDS dementia complex: Results of a placebo-controlled trial. Annals of Neurology, 33, 343–349. doi:10.1002/ana.410330403.PubMedCrossRef Sidtis, J. J., Gatsonis, C., Price, R. W., Singer, E. J., Collier, A. C., Richman, D. D., et al. (1993). Zidovudine treatment of the AIDS dementia complex: Results of a placebo-controlled trial. Annals of Neurology, 33, 343–349. doi:10.​1002/​ana.​410330403.PubMedCrossRef
Zurück zum Zitat Simoni, J. M., Kurth, A. E., Pearson, C. R., Pantalone, D. W., Merrill, J. O., & Frick, P. A. (2006). Self-report measures of antiretroviral therapy adherence: A review with recommendations for HIV research and clinical management. AIDS and Behavior, 10, 227–245. doi:10.1007/s10461-006-9078-6.PubMedCrossRef Simoni, J. M., Kurth, A. E., Pearson, C. R., Pantalone, D. W., Merrill, J. O., & Frick, P. A. (2006). Self-report measures of antiretroviral therapy adherence: A review with recommendations for HIV research and clinical management. AIDS and Behavior, 10, 227–245. doi:10.​1007/​s10461-006-9078-6.PubMedCrossRef
Zurück zum Zitat Smith, A. (1982). Symbol digit modalities test (SDMT) manual (revised). Los Angeles, CA: Western Psychological Association. Smith, A. (1982). Symbol digit modalities test (SDMT) manual (revised). Los Angeles, CA: Western Psychological Association.
Zurück zum Zitat Solomon, T. M., & Halkitis, P. N. (2008). Cognitive executive functioning in relation to HIV medication adherence among gay, bisexual, and other men who have sex with men. AIDS and Behavior, 12, 68–77. doi:10.1007/s10461-007-9273-0.PubMedCrossRef Solomon, T. M., & Halkitis, P. N. (2008). Cognitive executive functioning in relation to HIV medication adherence among gay, bisexual, and other men who have sex with men. AIDS and Behavior, 12, 68–77. doi:10.​1007/​s10461-007-9273-0.PubMedCrossRef
Zurück zum Zitat Starace, F., Ammassari, A., Trotta, M. P., Murri, R., De Longis, P., Izzo, C., et al. (2002). Depression is a risk factor for suboptimal adherence to highly active antiretroviral therapy. Journal of Acquired Immune Deficiency Syndromes, 31, S136–S139.PubMed Starace, F., Ammassari, A., Trotta, M. P., Murri, R., De Longis, P., Izzo, C., et al. (2002). Depression is a risk factor for suboptimal adherence to highly active antiretroviral therapy. Journal of Acquired Immune Deficiency Syndromes, 31, S136–S139.PubMed
Zurück zum Zitat Tiffin, J. (1968). Purdue Pegboard: Examiner manual. Chicago, IL: Science Research Associates. Tiffin, J. (1968). Purdue Pegboard: Examiner manual. Chicago, IL: Science Research Associates.
Zurück zum Zitat Waldrop-Valverde, D., Ownby, R. L., Wilkie, F. L., Mack, A., Kumar, M., & Metsch, L. (2006). Neurocognitive aspects of medication adherence in HIV-positive injecting drug users. AIDS and Behavior, 10, 287–297. doi:10.1007/s10461-005-9062-6.PubMedCrossRef Waldrop-Valverde, D., Ownby, R. L., Wilkie, F. L., Mack, A., Kumar, M., & Metsch, L. (2006). Neurocognitive aspects of medication adherence in HIV-positive injecting drug users. AIDS and Behavior, 10, 287–297. doi:10.​1007/​s10461-005-9062-6.PubMedCrossRef
Zurück zum Zitat Wechsler, D. (1981). Wechsler adult intelligence scale-revised. New York, NY: The Psychological Corporation. Wechsler, D. (1981). Wechsler adult intelligence scale-revised. New York, NY: The Psychological Corporation.
Zurück zum Zitat Wechsler, D. (1997). Wechsler adult intelligence scale manual (3rd ed.). New York, NY: The Psychological Corporation. Wechsler, D. (1997). Wechsler adult intelligence scale manual (3rd ed.). New York, NY: The Psychological Corporation.
Zurück zum Zitat Wetzel, L., & Boll, T. J. (1987). Short category test, booklet format. Los Angeles, CA: Western Psychological Association. Wetzel, L., & Boll, T. J. (1987). Short category test, booklet format. Los Angeles, CA: Western Psychological Association.
Zurück zum Zitat Woods, S. P., Moran, L. M., Carey, C. L., Dawson, M. S., Iudicello, J. E., Gibson, S., et al. (2008). Prospective memory in HIV infection: is “remembering to remember” a unique predictor of self-reported medication management? Archives of Clinical Neuropsychology, 23, 257–270. doi:10.1016/j.acn.2007.12.006.PubMedCrossRef Woods, S. P., Moran, L. M., Carey, C. L., Dawson, M. S., Iudicello, J. E., Gibson, S., et al. (2008). Prospective memory in HIV infection: is “remembering to remember” a unique predictor of self-reported medication management? Archives of Clinical Neuropsychology, 23, 257–270. doi:10.​1016/​j.​acn.​2007.​12.​006.PubMedCrossRef
Metadaten
Titel
The relationship between neuropsychological functioning and HAART adherence in HIV-positive adults: a systematic review
verfasst von
Travis I. Lovejoy
Julie A. Suhr
Publikationsdatum
01.10.2009
Verlag
Springer US
Erschienen in
Journal of Behavioral Medicine / Ausgabe 5/2009
Print ISSN: 0160-7715
Elektronische ISSN: 1573-3521
DOI
https://doi.org/10.1007/s10865-009-9212-9

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