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Journal of Clinical Immunology

Erschienen in:

01.08.2013 | Key Review Article

Chronic Recurrent Multifocal Osteomyelitis

verfasst von: Patrícia Costa-Reis, Kathleen E. Sullivan

Erschienen in: Journal of Clinical Immunology | Ausgabe 6/2013

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Abstract

Chronic recurrent multifocal osteomyelitis is a rare auto-inflammatory condition that primarily affects children and adolescents. It presents with recurrent episodes of pain related to the presence of foci of sterile bone inflammation. The long bones of the lower extremities are more frequently affected and the spine can also be involved. Imaging studies, including whole-body magnetic resonance, are important for diagnosis and detection of asymptomatic lesions. Bone biopsies may be necessary to exclude other diseases, including malignancy and infections. Non-steroidal anti-inflammatory drugs cause relief of symptoms in the majority of cases. Bisphosphonates and TNF-α blockers are alternatives for patients who do not respond or who have spinal involvement.

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Titel: Chronic Recurrent Multifocal Osteomyelitis
verfasst von: Patrícia Costa-Reis
Kathleen E. Sullivan
Publikationsdatum: 01.08.2013
Verlag: Springer US
Erschienen in: Journal of Clinical Immunology / Ausgabe 6/2013
Print ISSN: 0271-9142
Elektronische ISSN: 1573-2592
DOI: https://doi.org/10.1007/s10875-013-9902-5

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Chronic Recurrent Multifocal Osteomyelitis

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