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Journal of Genetic Counseling

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01.08.2014 | Next Generation Genetic Counseling

A Genetic Counselor’s Guide to Using Next-Generation Sequencing in Clinical Practice

verfasst von: Flavia M. Facio, Kristy Lee, Julianne M. O’Daniel

Erschienen in: Journal of Genetic Counseling | Ausgabe 4/2014

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Abstract

Advances in next-generation sequencing (NGS) and rapid reductions in cost have increased the use of such technologies in research and clinical practice. However, many barriers exist to translating NGS for routine clinical use, including issues related to the interpretation of results, and the potential to find results that are secondary or incidental to the specific application of NGS. Nonetheless, NGS has become sufficiently affordable to be offered by several clinical laboratories, and increasingly it is becoming an attractive and viable option for clinicians and patients. This article reviews current NGS technologies, highlighting the information genetic counselors need to know to make informed-decisions about utilizing NGS in the clinic, and underscoring the impact of this new testing modality on the practice of genetic counseling.

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Titel: A Genetic Counselor’s Guide to Using Next-Generation Sequencing in Clinical Practice
verfasst von: Flavia M. Facio
Kristy Lee
Julianne M. O’Daniel
Publikationsdatum: 01.08.2014
Verlag: Springer US
Erschienen in: Journal of Genetic Counseling / Ausgabe 4/2014
Print ISSN: 1059-7700
Elektronische ISSN: 1573-3599
DOI: https://doi.org/10.1007/s10897-013-9662-7

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A Genetic Counselor’s Guide to Using Next-Generation Sequencing in Clinical Practice

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