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Metabolic Brain Disease

Erschienen in:

01.06.2013 | Original Paper

In vivo studies of brain metabolism in animal models of Hepatic Encephalopathy using ¹H Magnetic Resonance Spectroscopy

verfasst von: Cristina Cudalbu

Erschienen in: Metabolic Brain Disease | Ausgabe 2/2013

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Abstract

Hepatic encephalopathy (HE) is a common and severe neuropsychiatric complication present in acute and chronic liver disease. The unique advantages of high field ¹H MRS provide a method for assessing pathogenic mechanism, diagnosis and monitoring of HE, as well as for treatment assessment or recovery after liver transplantation, in a reproducible and reliable non-invasive way. The purpose of the present review is to present some new features of in vivo proton Magnetic Resonance Spectroscopy (¹H MRS) at high magnetic fields combined with some basic requirements for reliable metabolic profiling. Finally, in vivo applications of ¹H MRS in different HE animal models are presented.

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Titel: In vivo studies of brain metabolism in animal models of Hepatic Encephalopathy using 1H Magnetic Resonance Spectroscopy
verfasst von: Cristina Cudalbu
Publikationsdatum: 01.06.2013
Verlag: Springer US
Erschienen in: Metabolic Brain Disease / Ausgabe 2/2013
Print ISSN: 0885-7490
Elektronische ISSN: 1573-7365
DOI: https://doi.org/10.1007/s11011-012-9368-9

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