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Journal of Neuro-Oncology
Erschienen in: Journal of Neuro-Oncology 3/2014

01.09.2014 | Topic Review

Medical therapy of gliomas

verfasst von: Manmeet S. Ahluwalia, Susan M. Chang

Erschienen in: Journal of Neuro-Oncology | Ausgabe 3/2014

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Abstract

Medical therapies are an important part of adjunctive therapy for gliomas. In this chapter we will review the chemotherapeutic and targeted agents that have been evaluated in clinical trials in grade II–IV gliomas in the last decade. A number of randomized phase III trials were completed and reported. There has been a clear success in oligodendroglial tumors and low grade glioma. Although some progress has been made in glioblastoma, considerable work involving the multidisciplinary collaboration of basic science, translational and clinical investigators needs to be done to improve the outcome of patients with anaplastic astrocytoma and glioblastoma. In addition, tailoring treatment based on molecular cytogenetic characteristics is a major focus of research into precision based medicine for glioma.
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Metadaten
Titel
Medical therapy of gliomas
verfasst von
Manmeet S. Ahluwalia
Susan M. Chang
Publikationsdatum
01.09.2014
Verlag
Springer US
Erschienen in
Journal of Neuro-Oncology / Ausgabe 3/2014
Print ISSN: 0167-594X
Elektronische ISSN: 1573-7373
DOI
https://doi.org/10.1007/s11060-014-1495-1

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