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Erschienen in: Quality of Life Research 3/2008

01.04.2008

The effects of exercise training on quality of life in HAART-treated HIV-positive Rwandan subjects with body fat redistribution

verfasst von: Eugene Mutimura, Aimee Stewart, Nigel J. Crowther, Kevin E. Yarasheski, W. Todd Cade

Erschienen in: Quality of Life Research | Ausgabe 3/2008

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Abstract

Objective

Our objective was to examine the effects of exercise training (EXS) on quality of life (QoL) in highly active antiretroviral therapy (HAART)-treated HIV-positive (HIV+) subjects with body fat redistribution (BFR) in Rwanda.

Methods

The effects of a randomised controlled trial of EXS on QoL were measured using World Health Organisation Quality of Life (WHOQOL)-BREF in HIV+ subjects with BFR randomised to EXS (n = 50; BFR + EXS) or no exercise training (n = 50; BFR + noEXS).

Results

At 6 months, scores on the psychological [1.3 (0.3) vs. 0.5 (0.1); P < 0.0001], independence [0.6 (0.1) vs. 0.0 (0.0); P < 0.0001], social relationships [0.6 (0.2) vs. 0.0 (0.0); P < 0.0001] and HIV HAART-specific QoL domains [1.4 (0.2) vs. −0.1 (0.2); P < 0.0001] improved more in BFR + EXS than BFR + noEXS group, respectively. Self-esteem [1.3 (0.8) vs. 0.1 (0.6); P < 0.001], body image [1.5 (0.6) vs. 0.0 (0.5); P < 0.001] and emotional stress [1.6 (0.7) vs. 0.2 (0.5); P < 0.001] improved more in the BFR + EXS group than BFR + noEXS group, respectively. Psychological [1.5 (0.2) vs. 1.1 (0.3); P < 0.0001], social relationship [0.8 (0.2) vs. 0.4 (0.2); P < 0.0001], and HIV HAART-specific well-being [1.8 (0.2) vs. 1.0 (0.0); P < 0.0001] improved more in BFR + EXS female than male subjects.

Conclusions

Exercise training improved several components of QoL in HAART-treated HIV+ African subjects with BFR. Exercise training is an inexpensive and efficacious strategy for improving QoL in HIV+ African subjects, which may improve HAART adherence and treatment initiatives in resource-limited areas of sub-Saharan Africa.
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Metadaten
Titel
The effects of exercise training on quality of life in HAART-treated HIV-positive Rwandan subjects with body fat redistribution
verfasst von
Eugene Mutimura
Aimee Stewart
Nigel J. Crowther
Kevin E. Yarasheski
W. Todd Cade
Publikationsdatum
01.04.2008
Verlag
Springer Netherlands
Erschienen in
Quality of Life Research / Ausgabe 3/2008
Print ISSN: 0962-9343
Elektronische ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-008-9319-4

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