Skip to main content
Erschienen in: Quality of Life Research 4/2009

01.05.2009

Quality of life of patients with irritable bowel syndrome in Korea

verfasst von: Jae Myung Park, Myung-Gyu Choi, Yong Sung Kim, Chang Hwan Choi, Suck Chei Choi, Su Jin Hong, Jeong Jo Jeong, Dong Ho Lee, Joon Seong Lee, Kwang Jae Lee, Hee Jung Son, In Kyung Sung

Erschienen in: Quality of Life Research | Ausgabe 4/2009

Einloggen, um Zugang zu erhalten

Abstract

Objective

The impact of irritable bowel syndrome (IBS) on HRQOL has been widely studied in the West. However, there are few data from Asian countries. The aim of this study was to assess the health-related quality of life (HRQOL) of patients suffering from IBS in Korea.

Methods

Consecutive patients from six secondary and six tertiary medical centers in Korea were enrolled and completed self-administered questionnaires on sociodemographics and IBS-associated symptoms. HRQOL was assessed using the generic Short Form 36 (SF-36) and the disease-specific IBS-QOL questionnaires.

Results

Of the 932 patients with abdominal pain and bowel symptoms, 664 IBS patients who fulfilled the Rome II criteria were analyzed. On all eight SF-36 scales, IBS patients had a significantly worse HRQOL than the general population (P < 0.01). The overall score for the IBS-QOL was 74.2. The health concern domain was most affected (mean score 64.2), and the sexual domain (mean score 86.7) was least affected in the IBS-QOL. Significant impairment of HRQOL was only observed in patients with severe symptoms both in the generic and specific HRQOL measurement, whereas patients with mild and moderate symptoms showed only mild impairment (P < 0.01). Female patients reported a significantly lower HRQOL than male patients (P < 0.05), but the difference was minimal. The IBS-QOL was significantly associated with female gender, total symptom score, self-reported symptom severity, and level of education in the multivariate analysis.

Conclusions

IBS-related symptoms had a great effect on the HRQOL of Korean patients. These results and the considerable prevalence of IBS in Korea indicate that IBS has a substantial social impact in this country.
Literatur
1.
Zurück zum Zitat Fitzpatrick, R., Fletcher, A., Gore, S., Jones, D., Spiegelhalter, D., & Cox, D. (1992). Quality of life measures in health care. I. Applications and issues in assessment. British Medical Journal, 305(6861), 1074–1077.PubMedCrossRef Fitzpatrick, R., Fletcher, A., Gore, S., Jones, D., Spiegelhalter, D., & Cox, D. (1992). Quality of life measures in health care. I. Applications and issues in assessment. British Medical Journal, 305(6861), 1074–1077.PubMedCrossRef
3.
Zurück zum Zitat Drossman, D. A. (1998). Presidential address: Gastrointestinal illness and biopsychosocial model. Psychosomatic Medicine, 60(3), 258–267.PubMed Drossman, D. A. (1998). Presidential address: Gastrointestinal illness and biopsychosocial model. Psychosomatic Medicine, 60(3), 258–267.PubMed
5.
Zurück zum Zitat Frank, L., Kleinman, L., Rentz, A., Ciesla, G., Kim, J. J., & Zacker, C. (2002). Health-related quality of life associated with irritable bowel syndrome: Comparison with other chronic diseases. Clinical Therapeutics, 24(4), 675–689. doi:10.1016/S0149-2918(02)85143-8.PubMedCrossRef Frank, L., Kleinman, L., Rentz, A., Ciesla, G., Kim, J. J., & Zacker, C. (2002). Health-related quality of life associated with irritable bowel syndrome: Comparison with other chronic diseases. Clinical Therapeutics, 24(4), 675–689. doi:10.​1016/​S0149-2918(02)85143-8.PubMedCrossRef
6.
Zurück zum Zitat Thompson, W. G., Longstreth, G. F., Drossman, D. A., Heaton, K. W., Irvine, E. J., & Muller-Lissner, S. A. (1999). Functional bowel disorders and functional abdominal pain. Gut, 45(Suppl 2), ii43–ii47.PubMedCrossRef Thompson, W. G., Longstreth, G. F., Drossman, D. A., Heaton, K. W., Irvine, E. J., & Muller-Lissner, S. A. (1999). Functional bowel disorders and functional abdominal pain. Gut, 45(Suppl 2), ii43–ii47.PubMedCrossRef
7.
Zurück zum Zitat Park, J. M., Choi, M. G., Oh, J. H., Cho, Y. K., Lee, I. S., Kim, S. W., et al. (2006). Cross-cultural validation of irritable bowel syndrome quality of life in Korea. Digestive Diseases and Sciences, 51(8), 1478–1484. doi:10.1007/s10620-006-9084-6.PubMedCrossRef Park, J. M., Choi, M. G., Oh, J. H., Cho, Y. K., Lee, I. S., Kim, S. W., et al. (2006). Cross-cultural validation of irritable bowel syndrome quality of life in Korea. Digestive Diseases and Sciences, 51(8), 1478–1484. doi:10.​1007/​s10620-006-9084-6.PubMedCrossRef
8.
Zurück zum Zitat Thompson, W. G., Longstreth, G. F., Drossman, D. A., Heaton, K. W., Irvine, E. J., Müller-Lissner, S. A.(2000). Functional bowel disorders and functional abdominal pain. In Rome II: The functional gastrointestinal disorders: Diagnosis, pathophysiology and treatment; A multinational consensus. McLean, VA: Degnon and Associates. Thompson, W. G., Longstreth, G. F., Drossman, D. A., Heaton, K. W., Irvine, E. J., Müller-Lissner, S. A.(2000). Functional bowel disorders and functional abdominal pain. In Rome II: The functional gastrointestinal disorders: Diagnosis, pathophysiology and treatment; A multinational consensus. McLean, VA: Degnon and Associates.
9.
Zurück zum Zitat Talley, N. J., Haque, M., Wyeth, J. W., Stace, N. H., Tytgat, G. N., Stanghellini, V., et al. (1998). Development of a new dyspepsia impact scale: the Nepean Dyspepsia Index. Alimentary Pharmacology and Therapeutics, 13(2), 225–235. doi:10.1046/j.1365-2036.1999.00445.x.CrossRef Talley, N. J., Haque, M., Wyeth, J. W., Stace, N. H., Tytgat, G. N., Stanghellini, V., et al. (1998). Development of a new dyspepsia impact scale: the Nepean Dyspepsia Index. Alimentary Pharmacology and Therapeutics, 13(2), 225–235. doi:10.​1046/​j.​1365-2036.​1999.​00445.​x.CrossRef
11.
Zurück zum Zitat Patrick, D. L., Drossman, D. A., Frederick, I. O., DiCesare, J., & Puder, K. L. (1998). Quality of life in persons with irritable bowel syndrome: Development of a new measure. Digestive Diseases and Sciences, 43(2), 400–411. doi:10.1023/A:1018831127942.PubMedCrossRef Patrick, D. L., Drossman, D. A., Frederick, I. O., DiCesare, J., & Puder, K. L. (1998). Quality of life in persons with irritable bowel syndrome: Development of a new measure. Digestive Diseases and Sciences, 43(2), 400–411. doi:10.​1023/​A:​1018831127942.PubMedCrossRef
12.
Zurück zum Zitat Drossman, D., Morris, C. B., Hu, Y., Toner, B. B., Diamant, N., Whitehead, W. E., et al. (2007). Characterization of health related quality of life (HRQOL) for patients with functional bowel disorder (FBD) and its response to treatment. The American Journal of Gastroenterology, 102(7), 1442–1453. doi:10.1111/j.1572-0241.2007.01283.x.PubMedCrossRef Drossman, D., Morris, C. B., Hu, Y., Toner, B. B., Diamant, N., Whitehead, W. E., et al. (2007). Characterization of health related quality of life (HRQOL) for patients with functional bowel disorder (FBD) and its response to treatment. The American Journal of Gastroenterology, 102(7), 1442–1453. doi:10.​1111/​j.​1572-0241.​2007.​01283.​x.PubMedCrossRef
13.
Zurück zum Zitat Kanazawa, M., Drossman, D. A., Shinozaki, M., Sagami, Y., Endo, Y., Palsson, O. S., et al. (2007). Translation and validation of a Japanese version of the irritable bowel syndrome-quality of life measure (IBS-QOL-J). BioPsychoSocial Medicine, 3, 1–6. Kanazawa, M., Drossman, D. A., Shinozaki, M., Sagami, Y., Endo, Y., Palsson, O. S., et al. (2007). Translation and validation of a Japanese version of the irritable bowel syndrome-quality of life measure (IBS-QOL-J). BioPsychoSocial Medicine, 3, 1–6.
14.
Zurück zum Zitat Kanazawa, M., Endo, Y., Whitehead, W. E., Kano, M., Hongo, M., & Fukudo, S. (2004). Patients and nonconsulters with irritable bowel syndrome reporting a parental history of bowel problems have more impaired psychological distress. Digestive Diseases and Sciences, 49(6), 1046–1053. doi:10.1023/B:DDAS.0000034570.52305.10.PubMedCrossRef Kanazawa, M., Endo, Y., Whitehead, W. E., Kano, M., Hongo, M., & Fukudo, S. (2004). Patients and nonconsulters with irritable bowel syndrome reporting a parental history of bowel problems have more impaired psychological distress. Digestive Diseases and Sciences, 49(6), 1046–1053. doi:10.​1023/​B:​DDAS.​0000034570.​52305.​10.PubMedCrossRef
15.
16.
Zurück zum Zitat Huang, W. W., Zhou, F. S., Bushnell, D. M., Diakite, C., & Yang, X. H. (2007). Cultural adaptation and application of the IBS-QOL in China: A disease-specific quality-of-life questionnaire. Quality of Life Research, 16(6), 991–996. doi:10.1007/s11136-006-9141-9.PubMedCrossRef Huang, W. W., Zhou, F. S., Bushnell, D. M., Diakite, C., & Yang, X. H. (2007). Cultural adaptation and application of the IBS-QOL in China: A disease-specific quality-of-life questionnaire. Quality of Life Research, 16(6), 991–996. doi:10.​1007/​s11136-006-9141-9.PubMedCrossRef
18.
Zurück zum Zitat Whitehead, W. E., Burnett, C. K., Cook, E. W., III., & Taub, E. (1996). Impact of irritable bowel syndrome on quality of life. Digestive Diseases and Sciences, 41(11), 2248–2253. doi:10.1007/BF02071408.PubMedCrossRef Whitehead, W. E., Burnett, C. K., Cook, E. W., III., & Taub, E. (1996). Impact of irritable bowel syndrome on quality of life. Digestive Diseases and Sciences, 41(11), 2248–2253. doi:10.​1007/​BF02071408.PubMedCrossRef
19.
Zurück zum Zitat Creed, F., Ratcliffe, J., Fernandez, L., Tomenson, B., Palmer, S., Rigby, C., et al. (2001). Health-related quality of life and health care costs in severe, refractory irritable bowel syndrome. Annals of Internal Medicine, 134(9), 860–868.PubMed Creed, F., Ratcliffe, J., Fernandez, L., Tomenson, B., Palmer, S., Rigby, C., et al. (2001). Health-related quality of life and health care costs in severe, refractory irritable bowel syndrome. Annals of Internal Medicine, 134(9), 860–868.PubMed
20.
Zurück zum Zitat Hahn, B. A., Yan, S., & Strassels, S. (1999). Impact of irritable bowel syndrome on quality of life and resource use in the United States and the United Kingdom. Digestion, 60(1), 77–81. doi:10.1159/000007593.PubMedCrossRef Hahn, B. A., Yan, S., & Strassels, S. (1999). Impact of irritable bowel syndrome on quality of life and resource use in the United States and the United Kingdom. Digestion, 60(1), 77–81. doi:10.​1159/​000007593.PubMedCrossRef
21.
Zurück zum Zitat Brun-Strang, C., Dapoigny, M., Lafuma, A., Wainsten, J. P., & Fagnani, F. (2007). Irritable bowel syndrome in France: Quality of life, medical management, and costs: The Encoli study. European Journal of Gastroenterology and Hepatology, 19(12), 1097–1103.PubMedCrossRef Brun-Strang, C., Dapoigny, M., Lafuma, A., Wainsten, J. P., & Fagnani, F. (2007). Irritable bowel syndrome in France: Quality of life, medical management, and costs: The Encoli study. European Journal of Gastroenterology and Hepatology, 19(12), 1097–1103.PubMedCrossRef
22.
Zurück zum Zitat Heaton, K. W., O’Donnell, L. J., Braddon, F. E., Mountford, R. A., Hughes, A. O., & Cripps, P. J. (1992). Symptoms of irritable bowel syndrome in a British urban community: Consulters and nonconsulters. Gastroenterology, 102(6), 1962–1967.PubMed Heaton, K. W., O’Donnell, L. J., Braddon, F. E., Mountford, R. A., Hughes, A. O., & Cripps, P. J. (1992). Symptoms of irritable bowel syndrome in a British urban community: Consulters and nonconsulters. Gastroenterology, 102(6), 1962–1967.PubMed
23.
Zurück zum Zitat Drossman, D. A., McKee, D. C., Sandler, R. S., Mitchell, C. M., Cramer, E. M., Lowman, B. C., et al. (1998). Psychosocial factors in the irritable bowel syndrome. A multivariate study of patients and nonpatients with irritable bowel syndrome. Gastroenterology, 95(3), 701–708. Drossman, D. A., McKee, D. C., Sandler, R. S., Mitchell, C. M., Cramer, E. M., Lowman, B. C., et al. (1998). Psychosocial factors in the irritable bowel syndrome. A multivariate study of patients and nonpatients with irritable bowel syndrome. Gastroenterology, 95(3), 701–708.
24.
Zurück zum Zitat Akehurst, R. L., Brazier, J. E., Mathers, N., O’Keefe, C., Kaltenthaler, E., Morgan, A., et al. (2002). Health-related quality of life and cost impact of irritable bowel syndrome in a UK primary care setting. PharmacoEconomics, 20(7), 455–462. doi:10.2165/00019053-200220070-00003.PubMedCrossRef Akehurst, R. L., Brazier, J. E., Mathers, N., O’Keefe, C., Kaltenthaler, E., Morgan, A., et al. (2002). Health-related quality of life and cost impact of irritable bowel syndrome in a UK primary care setting. PharmacoEconomics, 20(7), 455–462. doi:10.​2165/​00019053-200220070-00003.PubMedCrossRef
25.
Zurück zum Zitat Corney, R. H., & Stanton, R. (1990). Physical symptom severity, psychological and social dysfunction in a series of outpatients with irritable bowel syndrome. Journal of Psychosomatic Research, 34(5), 483–491. doi:10.1016/0022-3999(90)90022-V.PubMedCrossRef Corney, R. H., & Stanton, R. (1990). Physical symptom severity, psychological and social dysfunction in a series of outpatients with irritable bowel syndrome. Journal of Psychosomatic Research, 34(5), 483–491. doi:10.​1016/​0022-3999(90)90022-V.PubMedCrossRef
26.
Zurück zum Zitat Spiegel, B. M., Gralnek, I. M., Bolus, R., Chang, L., Dulai, G. S., Mayer, E. A., et al. (2004). Clinical determinants of health-related quality of life in patients with irritable bowel syndrome. Archives of Internal Medicine, 164(16), 1773–1780. doi:10.1001/archinte.164.16.1773.PubMedCrossRef Spiegel, B. M., Gralnek, I. M., Bolus, R., Chang, L., Dulai, G. S., Mayer, E. A., et al. (2004). Clinical determinants of health-related quality of life in patients with irritable bowel syndrome. Archives of Internal Medicine, 164(16), 1773–1780. doi:10.​1001/​archinte.​164.​16.​1773.PubMedCrossRef
29.
Zurück zum Zitat Houghton, L. A., Lea, R., Jackson, N., & Whorwell, P. J. (2002). The menstrual cycle affects rectal sensitivity in patients with irritable bowel syndrome but not healthy volunteers. Gut, 50(4), 471–474. doi:10.1136/gut.50.4.471.PubMedCrossRef Houghton, L. A., Lea, R., Jackson, N., & Whorwell, P. J. (2002). The menstrual cycle affects rectal sensitivity in patients with irritable bowel syndrome but not healthy volunteers. Gut, 50(4), 471–474. doi:10.​1136/​gut.​50.​4.​471.PubMedCrossRef
30.
Zurück zum Zitat Whitehead, W. E., Cheskin, L. J., Heller, B. R., Robinson, J. C., Crowell, M. D., Benjamin, C., et al. (1990). Evidence for exacerbation of irritable bowel syndrome during menses. Gastroenterology, 98(6), 1485–1489.PubMed Whitehead, W. E., Cheskin, L. J., Heller, B. R., Robinson, J. C., Crowell, M. D., Benjamin, C., et al. (1990). Evidence for exacerbation of irritable bowel syndrome during menses. Gastroenterology, 98(6), 1485–1489.PubMed
31.
Zurück zum Zitat Blanchard, E. B., Keefer, L., Galovski, T. E., Taylor, A. E., & Turner, S. M. (2001). Gender differences in psychological distress among patients with irritable bowel syndrome. Journal of Psychosomatic Research, 50(5), 271–275. doi:10.1016/S0022-3999(01)00207-0.PubMedCrossRef Blanchard, E. B., Keefer, L., Galovski, T. E., Taylor, A. E., & Turner, S. M. (2001). Gender differences in psychological distress among patients with irritable bowel syndrome. Journal of Psychosomatic Research, 50(5), 271–275. doi:10.​1016/​S0022-3999(01)00207-0.PubMedCrossRef
32.
Zurück zum Zitat Taylor, S. E., Klein, L. C., Lewis, B. P., Gruenewald, T. L., Gurung, R. A., & Updegraff, J. A. (2000). Biobehavioral responses to stress in females: Tend-and-befriend, not fight-or-flight. Psychological Review, 107(3), 411–429. doi:10.1037/0033-295X.107.3.411.PubMedCrossRef Taylor, S. E., Klein, L. C., Lewis, B. P., Gruenewald, T. L., Gurung, R. A., & Updegraff, J. A. (2000). Biobehavioral responses to stress in females: Tend-and-befriend, not fight-or-flight. Psychological Review, 107(3), 411–429. doi:10.​1037/​0033-295X.​107.​3.​411.PubMedCrossRef
33.
Zurück zum Zitat Hahn, B. A., Kirchdoerfer, L. J., Fullerton, S., & Mayer, E. (1997). Patient-perceived severity of irritable bowel syndrome in relation to symptoms, health resource utilization and quality of life. Alimentary Pharmacology and Therapeutics, 11(3), 553–559. doi:10.1046/j.1365-2036.1997.00160.x.PubMedCrossRef Hahn, B. A., Kirchdoerfer, L. J., Fullerton, S., & Mayer, E. (1997). Patient-perceived severity of irritable bowel syndrome in relation to symptoms, health resource utilization and quality of life. Alimentary Pharmacology and Therapeutics, 11(3), 553–559. doi:10.​1046/​j.​1365-2036.​1997.​00160.​x.PubMedCrossRef
34.
Zurück zum Zitat Sprangers, M. A., de Regt, E. B., Andries, F., van Agt, H. M., Bijl, R. V., de Boer, J. B., et al. (2000). Which chronic conditions are associated with better or poorer quality of life? Journal of Clinical Epidemiology, 53(9), 895–907. doi:10.1016/S0895-4356(00)00204-3.PubMedCrossRef Sprangers, M. A., de Regt, E. B., Andries, F., van Agt, H. M., Bijl, R. V., de Boer, J. B., et al. (2000). Which chronic conditions are associated with better or poorer quality of life? Journal of Clinical Epidemiology, 53(9), 895–907. doi:10.​1016/​S0895-4356(00)00204-3.PubMedCrossRef
35.
Zurück zum Zitat Tillisch, K., Labus, J. S., Naliboff, B. D., Bolus, R., Shetzline, M., Mayer, E. A., et al. (2005). Characterization of the alternating bowel habit subtype in patients with irritable bowel syndrome. The American Journal of Gastroenterology, 100(4), 896–904. doi:10.1111/j.1572-0241.2005.41211.x.PubMedCrossRef Tillisch, K., Labus, J. S., Naliboff, B. D., Bolus, R., Shetzline, M., Mayer, E. A., et al. (2005). Characterization of the alternating bowel habit subtype in patients with irritable bowel syndrome. The American Journal of Gastroenterology, 100(4), 896–904. doi:10.​1111/​j.​1572-0241.​2005.​41211.​x.PubMedCrossRef
Metadaten
Titel
Quality of life of patients with irritable bowel syndrome in Korea
verfasst von
Jae Myung Park
Myung-Gyu Choi
Yong Sung Kim
Chang Hwan Choi
Suck Chei Choi
Su Jin Hong
Jeong Jo Jeong
Dong Ho Lee
Joon Seong Lee
Kwang Jae Lee
Hee Jung Son
In Kyung Sung
Publikationsdatum
01.05.2009
Verlag
Springer Netherlands
Erschienen in
Quality of Life Research / Ausgabe 4/2009
Print ISSN: 0962-9343
Elektronische ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-009-9461-7

Weitere Artikel der Ausgabe 4/2009

Quality of Life Research 4/2009 Zur Ausgabe