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Quality of Life Research
Erschienen in: Quality of Life Research 6/2011

01.08.2011

Marginal differences in health-related quality of life of diabetic patients with and without macrovascular comorbid conditions in the United States

verfasst von: Alex Z. Fu, Ying Qiu, Larry Radican, Nan Luo

Erschienen in: Quality of Life Research | Ausgabe 6/2011

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Abstract

Purpose

To examine and quantify, at the US national level, the marginal differences in health-related quality of life (HRQoL) of diabetic patients with and without macrovascular comorbid conditions (MaVCC).

Methods

Using the pooled Medical Expenditure Panel Survey (MEPS) 2001 and 2003 data, a nationally representative community-dwelling adult sample (age ≥ 18) was included in the study. HRQoL measures included the preference-based EQ-5D index, Euroqol visual analogue scale (EQ-VAS), SF-12 physical component summary (PCS), and SF-12 mental component summary (MCS). Given the censored distribution of the data, a two-part model was used to identify the relationship between MaVCC and the EQ-5D index after controlling for age, sex, race, ethnicity, education, income, employment status, health insurance, smoking status, diabetes severity, and comorbidities. Censored least absolute deviation and ordinary least square models were employed to analyze EQ-VAS and SF-12 PCS/MCS, respectively.

Results

Compared to diabetic patients without MaVCC (N = 2431), those with MaVCC (N = 747) had significantly lower EQ-5D index (−0.062), EQ-VAS (−9.2), SF-12 PCS (−5.0), and MCS (−2.1) after controlling for differences in sociodemographics, smoking status, diabetes severity, and comorbidities (all P < 0.001).

Conclusions

MaVCC is consistently associated with lower HRQoL for patients with diabetes in the United States. Results of this study are valuable for future comparative-effectiveness and cost-effectiveness analyses in diabetes.
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Metadaten
Titel
Marginal differences in health-related quality of life of diabetic patients with and without macrovascular comorbid conditions in the United States
verfasst von
Alex Z. Fu
Ying Qiu
Larry Radican
Nan Luo
Publikationsdatum
01.08.2011
Verlag
Springer Netherlands
Erschienen in
Quality of Life Research / Ausgabe 6/2011
Print ISSN: 0962-9343
Elektronische ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-010-9819-x

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